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October 30, 2019 @ 12:00 pm – 1:00 pm
Magee-Womens Research Institute, Conference Center, 1st Floor
Speaker: Moses Turkle Bility, PhD
Title: Assistant Professor, Dept of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh
Lecture Title: Modeling sexually transmitted diseases and immuno-oncology in rodents with human organ systems
It is well established that species differences exist in susceptibility to infectious diseases. Additionally, significant species-specific differences exist in the immune response to infectious agents and neoplasia. To overcome the species-specific difference between rodents and humans, we have reconstituted immunodeficient rodents with requisite human organ systems for investigating sexually transmitted diseases (i.e. HIV) and immuno-oncology (i.e. ovarian cancer).