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Yvonne Chao

Yvonne Chao

Program: Cancer Biology

(412) 623-2211 chaoyl@upmc.edu 5150 Centre Ave, 5th floor
Pittsburgh PA
Summary

Because metastases account for the majority of mortality from cancer, my research interests center on elucidating the pathobiology of metastasis and using these discoveries to develop therapeutic targets. I am also interested in developing more sophisticated models of cancer metastasis that better incorporate the tumor microenvironment. In my research career thus far I have developed novel models and techniques for studying metastasis that have revealed mechanisms of how the liver, lymph node, and immune microenvironments may uniquely impact cancer cells. We are currently exploring the roles of a class of non-coding RNAs called small nucleolar RNAs (snoRNAs) in metastasis from lymph nodes in breast and lung cancer.

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