Publications

Mechanisms of Genome Stability

Morariu EM, McCoy KL, Chiosea SI, Nikitski AV, Manroa P, Nikiforova MN, Nikiforov YE. Clinicopathologic Characteristics of Thyroid Nodules Positive for the THADA-IGF2BP3 Fusion on Preoperative Molecular Analysis. Thyroid. 2021-08-01;31(8):1212-1218. doi: 10.1089/thy.2020.0589. PubMed PMID: 33487086.
Van Houten B, Schnable B, Kumar N. Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage detection hand-offs during nucleotide excision repair. Bioessays. 2021-05-01;43(5):e2100011. doi: 10.1002/bies.202100011. PubMed PMID: 33620094.
Chong AS, Nikiforov YE, Condello V, Wald AI, Nikiforova MN, Foulkes WD, Rivera B. Prevalence and Spectrum of DICER1 Mutations in Adult-onset Thyroid Nodules with Indeterminate Cytology. J Clin Endocrinol Metab. 2021-03-25;106(4):968-977. doi: 10.1210/clinem/dgab025. PubMed PMID: 33460435.
Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. Chromothripsis drives the evolution of gene amplification in cancer. Nature. 2021-03-01;591(7848):137-141. doi: 10.1038/s41586-020-03064-z. PubMed PMID: 33361815; PMCID: PMC7933129.
Karapetyan L, Yang X, Wang H, Sander CA, Moyer A, Wilson M, Karunamurthy A, Kirkwood JM. Indoor tanning exposure in association with multiple primary melanoma. Cancer. 2021-02-15;127(4):560-568. doi: 10.1002/cncr.33307. PubMed PMID: 33170961.
Stabile LP, Kumar V, Gaither-Davis A, Huang EH, Vendetti FP, Devadassan P, Dacic S, Bao R, Steinman RA, Burns TF, Bakkenist CJ. Syngeneic tobacco carcinogen-induced mouse lung adenocarcinoma model exhibits PD-L1 expression and high tumor mutational burden. JCI Insight. 2021-02-08;6(3): doi: 10.1172/jci.insight.145307. PubMed PMID: 33351788; PMCID: PMC7934870.
Anthonymuthu TS, Tyurina YY, Sun WY, Mikulska-Ruminska K, Shrivastava IH, Tyurin VA, Cinemre FB, Dar HH, VanDemark AP, Holman TR, Sadovsky Y, Stockwell BR, He RR, Bahar I, Bayır H, Kagan VE. Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis. Redox Biol. 2021-01-01;38101744. doi: 10.1016/j.redox.2020.101744. PubMed PMID: 33126055; PMCID: PMC7596334.
Duncan AW. Hepatocyte ploidy modulation in liver cancer. EMBO Rep. 2020-12-03;21(12):e51922. doi: 10.15252/embr.202051922. PubMed PMID: 33237586; PMCID: PMC7726811.
Hu XT, Xing W, Zhao RS, Tan Y, Wu XF, Ao LQ, Li Z, Yao MW, Yuan M, Guo W, Li SZ, Yu J, Ao X, Xu X. HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer. J Exp Clin Cancer Res. 2020-12-02;39(1):270. doi: 10.1186/s13046-020-01783-9. PubMed PMID: 33267897; PMCID: PMC7709355.
Perego M, Tyurin VA, Tyurina YY, Yellets J, Nacarelli T, Lin C, Nefedova Y, Kossenkov A, Liu Q, Sreedhar S, Pass H, Roth J, Vogl T, Feldser D, Zhang R, Kagan VE, Gabrilovich DI. Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils. Sci Transl Med. 2020-12-02;12(572): doi: 10.1126/scitranslmed.abb5817. PubMed PMID: 33268511; PMCID: PMC8085740.
Hoang SM, Kaminski N, Bhargava R, Barroso-González J, Lynskey ML, García-Expósito L, Roncaioli JL, Wondisford AR, Wallace CT, Watkins SC, James DI, Waddell ID, Ogilvie D, Smith KM, da Veiga Leprevost F, Mellacharevu D, Nesvizhskii AI, Li J, Ray-Gallet D, Sobol RW, Almouzni G, O'Sullivan RJ. Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nat Struct Mol Biol. 2020-12-01;27(12):1152-1164. doi: 10.1038/s41594-020-0512-7. PubMed PMID: 33046907; PMCID: PMC7809635.
Lizardo DY, Kuang C, Hao S, Yu J, Huang Y, Zhang L. Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside. Biochim Biophys Acta Rev Cancer. 2020-12-01;1874(2):188447. doi: 10.1016/j.bbcan.2020.188447. PubMed PMID: 33035640; PMCID: PMC7886024.
Toptan T, Cantrell PS, Zeng X, Liu Y, Sun M, Yates NA, Chang Y, Moore PS. Proteomic approach to discover human cancer viruses from formalin-fixed tissues. JCI Insight. 2020-11-19;5(22): doi: 10.1172/jci.insight.143003. PubMed PMID: 33055416; PMCID: PMC7710300.
Kumar N, Raja S, Van Houten B. The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage. Nucleic Acids Res. 2020-11-18;48(20):11227-11243. doi: 10.1093/nar/gkaa777. PubMed PMID: 33010169; PMCID: PMC7672477.
Ruan H, Li X, Xu X, Leibowitz BJ, Tong J, Chen L, Ao L, Xing W, Luo J, Yu Y, Schoen RE, Sonenberg N, Lu X, Zhang L, Yu J. eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis. Elife. 2020-11-02;9 doi: 10.7554/eLife.60151. PubMed PMID: 33135632; PMCID: PMC7665890.
Houston R, Sekine S, Calderon MJ, Seifuddin F, Wang G, Kawagishi H, Malide DA, Li Y, Gucek M, Pirooznia M, Nelson AJ, Stokes MP, Stewart-Ornstein J, Mullett SJ, Wendell SG, Watkins SC, Finkel T, Sekine Y. Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. PLoS Biol. 2020-11-01;18(11):e3000981. doi: 10.1371/journal.pbio.3000981. PubMed PMID: 33253182; PMCID: PMC7728262.
Zhu RY, Majumdar C, Khuu C, De Rosa M, Opresko PL, David SS, Kool ET. Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity. ACS Cent Sci. 2020-10-28;6(10):1735-1742. doi: 10.1021/acscentsci.0c00369. PubMed PMID: 33145410; PMCID: PMC7596860.
Pham D, Deter CJ, Reinard MC, Gibson GA, Kiselyov K, Yu W, Sandulache VC, St Croix CM, Koide K. Using Ligand-Accelerated Catalysis to Repurpose Fluorogenic Reactions for Platinum or Copper. ACS Cent Sci. 2020-10-28;6(10):1772-1788. doi: 10.1021/acscentsci.0c00676. PubMed PMID: 33145414; PMCID: PMC7596870.
Wiernicki B, Dubois H, Tyurina YY, Hassannia B, Bayir H, Kagan VE, Vandenabeele P, Wullaert A, Vanden Berghe T. Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis. Cell Death Dis. 2020-10-27;11(10):922. doi: 10.1038/s41419-020-03118-0. PubMed PMID: 33110056; PMCID: PMC7591475.
Sanford SL, Welfer GA, Freudenthal BD, Opresko PL. Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs. Nat Commun. 2020-10-20;11(1):5288. doi: 10.1038/s41467-020-19115-y. PubMed PMID: 33082336; PMCID: PMC7576608.
Liu J, Zuo Z, Zou M, Finkel T, Liu S. Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen. PLoS Genet. 2020-10-01;16(10):e1009068. doi: 10.1371/journal.pgen.1009068. PubMed PMID: 33057331; PMCID: PMC7591051.
Kong M, Beckwitt EC, Van Houten B. Dynamic action of DNA repair proteins as revealed by single molecule techniques: Seeing is believing. DNA Repair (Amst). 2020-09-01;93102909. doi: 10.1016/j.dnarep.2020.102909. PubMed PMID: 33087275; PMCID: PMC7586736.
Grundy MK, Buckanovich RJ, Bernstein KA. Regulation and pharmacological targeting of RAD51 in cancer. NAR Cancer. 2020-09-01;2(3):zcaa024. doi: 10.1093/narcan/zcaa024. PubMed PMID: 33015624; PMCID: PMC7520849.
Ma H, Wang P, Shang D, Liu Y. Spatial-domain low-coherence quantitative phase microscopy to improve the cytological diagnosis of pancreatic cancer. J Investig Med. 2020-01-01;68(1):60-67. doi: 10.1136/jim-2019-000997. PubMed PMID: 31324696.
Malik N, Nikitski AV, Klam E, Hunt J, Witt B, Chadwick B, Nikiforov YE, Abraham D. MOLECULAR PROFILE AND CLINICAL OUTCOMES IN DIFFERENTIATED THYROID CANCER PATIENTS PRESENTING WITH BONE METASTASIS. Endocr Pract. 2019-12-01;25(12):1255-1262. doi: 10.4158/EP-2019-0265. PubMed PMID: 31412230.
Nikitski AV, Rominski SL, Condello V, Kaya C, Wankhede M, Panebianco F, Yang H, Altschuler DL, Nikiforov YE. Mouse Model of Thyroid Cancer Progression and Dedifferentiation Driven by STRN-ALK Expression and Loss of p53: Evidence for the Existence of Two Types of Poorly Differentiated Carcinoma. Thyroid. 2019-10-01;29(10):1425-1437. doi: 10.1089/thy.2019.0284. PubMed PMID: 31298630; PMCID: PMC6797076.
Panebianco F, Nikitski AV, Nikiforova MN, Nikiforov YE. Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer. Cancer Med. 2019-10-01;8(13):5831-5839. doi: 10.1002/cam4.2467. PubMed PMID: 31408918; PMCID: PMC6792496.
Cucinotta CE, Hildreth AE, McShane BM, Shirra MK, Arndt KM. The nucleosome acidic patch directly interacts with subunits of the Paf1 and FACT complexes and controls chromatin architecture in vivo. Nucleic Acids Res. 2019-09-19;47(16):8410-8423. doi: 10.1093/nar/gkz549. PubMed PMID: 31226204; PMCID: PMC6895269.
Werner HM, Estabrooks SK, Preston GM, Brodsky JL, Horne WS. Exploring the Functional Consequences of Protein Backbone Alteration in Ubiquitin through Native Chemical Ligation. Chembiochem. 2019-09-16;20(18):2346-2350. doi: 10.1002/cbic.201900225. PubMed PMID: 31059184; PMCID: PMC6752966.
Nikiforova MN, Nikiforov YE, Ohori NP. GLIS rearrangements in thyroid nodules: A key to preoperative diagnosis of hyalinizing trabecular tumor. Cancer Cytopathol. 2019-09-01;127(9):560-566. doi: 10.1002/cncy.22163. PubMed PMID: 31373774.
Borrelli N, Panebianco F, Condello V, Barletta JA, Kaya C, Yip L, Nikiforova MN, Nikiforov YE. Characterization of Activating Mutations of the MEK1 Gene in Papillary Thyroid Carcinomas. Thyroid. 2019-09-01;29(9):1279-1285. doi: 10.1089/thy.2019.0065. PubMed PMID: 31407636; PMCID: PMC6913803.
Bakkenist CJ, Czambel RK, Lin Y, Yates NA, Zeng X, Shogan J, Schmitz JC. Quantitative analysis of ATM phosphorylation in lymphocytes. DNA Repair (Amst). 2019-08-01;801-7. doi: 10.1016/j.dnarep.2019.06.002. PubMed PMID: 31176958; PMCID: PMC6708498.
Shao L, Hou W, Scharping NE, Vendetti FP, Srivastava R, Roy CN, Menk AV, Wang Y, Chauvin JM, Karukonda P, Thorne SH, Hornung V, Zarour HM, Bakkenist CJ, Delgoffe GM, Sarkar SN. IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell. Cancer Immunol Res. 2019-08-01;7(8):1258-1266. doi: 10.1158/2326-6066.CIR-18-0711. PubMed PMID: 31239318; PMCID: PMC6677597.
Leonard BC, Lee ED, Bhola NE, Li H, Sogaard KK, Bakkenist CJ, Grandis JR, Johnson DE. ATR inhibition sensitizes HPV- and HPV+ head and neck squamous cell carcinoma to cisplatin. Oral Oncol. 2019-08-01;9535-42. doi: 10.1016/j.oraloncology.2019.05.028. PubMed PMID: 31345392; PMCID: PMC6827881.
Uttam S, Hashash JG, LaFace J, Binion D, Regueiro M, Hartman DJ, Brand RE, Liu Y. Three-Dimensional Nanoscale Nuclear Architecture Mapping of Rectal Biopsies Detects Colorectal Neoplasia in Patients with Inflammatory Bowel Disease. Cancer Prev Res (Phila). 2019-08-01;12(8):527-538. doi: 10.1158/1940-6207.CAPR-19-0024. PubMed PMID: 31164345; PMCID: PMC6677599.
Xu J, Liu Y. A guide to visualizing the spatial epigenome with super-resolution microscopy. FEBS J. 2019-08-01;286(16):3095-3109. doi: 10.1111/febs.14938. PubMed PMID: 31127980; PMCID: PMC6699889.
Needham PG, Guerriero CJ, Brodsky JL. Chaperoning Endoplasmic Reticulum-Associated Degradation (ERAD) and Protein Conformational Diseases. Cold Spring Harb Perspect Biol. 2019-08-01;11(8): doi: 10.1101/cshperspect.a033928. PubMed PMID: 30670468; PMCID: PMC6671943.
Sun J, Wang C, Zhang Y, Xu L, Fang W, Zhu Y, Zheng Y, Chen X, Xie X, Hu X, Hu W, Zheng J, Li P, Yu J, Mei Z, Cai X, Wang B, Hu Z, Shu Y, Shen H, Gu Y. Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases. Nat Commun. 2019-07-18;10(1):3190. doi: 10.1038/s41467-019-10987-3. PubMed PMID: 31320627; PMCID: PMC6639368.
Han S, Ehrhardt J Jr, Shukla S, Elkbuli A, Nikiforov YE, Gulec SA. A Case of Papillary Thyroid Carcinoma and Kostmann Syndrome: A Genomic Theranostic Approach for Comprehensive Treatment. Am J Case Rep. 2019-07-16;201027-1034. doi: 10.12659/AJCR.916143. PubMed PMID: 31308356; PMCID: PMC6647623.
Fouquerel E, Barnes RP, Uttam S, Watkins SC, Bruchez MP, Opresko PL. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019-07-11;75(1):117-130.e6. doi: 10.1016/j.molcel.2019.04.024. PubMed PMID: 31101499; PMCID: PMC6625854.
Yu C, Liu Q, Chen C, Yu J, Wang J. Landscape perspectives of tumor, EMT, and development. Phys Biol. 2019-07-05;16(5):051003. doi: 10.1088/1478-3975/ab2029. PubMed PMID: 31067516.
Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H, Brodsky JL, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 2019-07-05;365(6448):53-60. doi: 10.1126/science.aau9263. PubMed PMID: 31273116; PMCID: PMC7062386.
Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E, Watkins SC, Bakkenist CJ. An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication. Proc Natl Acad Sci U S A. 2019-07-02;116(27):13374-13383. doi: 10.1073/pnas.1903418116. PubMed PMID: 31209037; PMCID: PMC6613105.
Piccirillo AR, Hyzny EJ, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM. The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection. J Immunol. 2019-07-01;203(1):117-126. doi: 10.4049/jimmunol.1801585. PubMed PMID: 31127034; PMCID: PMC6581627.
Sehrawat A, Samanta SK, Hahm ER, St Croix C, Watkins S, Singh SV. Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics. Mitochondrion. 2019-07-01;47282-293. doi: 10.1016/j.mito.2019.01.003. PubMed PMID: 30685490; PMCID: PMC6599725.
Hamsanathan S, Alder JK, Sellares J, Rojas M, Gurkar AU, Mora AL. Cellular Senescence: The Trojan Horse in Chronic Lung Diseases. Am J Respir Cell Mol Biol. 2019-07-01;61(1):21-30. doi: 10.1165/rcmb.2018-0410TR. PubMed PMID: 30965013; PMCID: PMC6604222.
Doonan LM, Guerriero CJ, Preston GM, Buck TM, Khazanov N, Fisher EA, Senderowitz H, Brodsky JL. Hsp104 facilitates the endoplasmic-reticulum-associated degradation of disease-associated and aggregation-prone substrates. Protein Sci. 2019-07-01;28(7):1290-1306. doi: 10.1002/pro.3636. PubMed PMID: 31050848; PMCID: PMC6566541.
Tyurina YY, Tyurin VA, Anthonymuthu T, Amoscato AA, Sparvero LJ, Nesterova AM, Baynard ML, Sun W, He R, Khaitovich P, Vladimirov YA, Gabrilovich DI, Bayır H, Kagan VE. "Redox lipidomics technology: Looking for a needle in a haystack". Chem Phys Lipids. 2019-07-01;22193-107. doi: 10.1016/j.chemphyslip.2019.03.012. PubMed PMID: 30928338; PMCID: PMC6714565.
Cai C, Cooper GF, Lu KN, Ma X, Xu S, Zhao Z, Chen X, Xue Y, Lee AV, Clark N, Chen V, Lu S, Chen L, Yu L, Hochheiser HS, Jiang X, Wang QJ, Lu X. Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference. PLoS Comput Biol. 2019-07-01;15(7):e1007088. doi: 10.1371/journal.pcbi.1007088. PubMed PMID: 31276486; PMCID: PMC6650088.
Ngo M, Wechter N, Tsai E, Shun TY, Gough A, Schurdak ME, Schwacha A, Vogt A. A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics. SLAS Discov. 2019-07-01;24(6):669-681. doi: 10.1177/2472555219829740. PubMed PMID: 30802412; PMCID: PMC6586513.
Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death. J Leukoc Biol. 2019-07-01;106(1):57-81. doi: 10.1002/JLB.3MIR0119-004RR. PubMed PMID: 31071242; PMCID: PMC6626990.
Ellison MA, Lederer AR, Warner MH, Mavrich TN, Raupach EA, Heisler LE, Nislow C, Lee MT, Arndt KM. The Paf1 Complex Broadly Impacts the Transcriptome of Saccharomyces cerevisiae. Genetics. 2019-07-01;212(3):711-728. doi: 10.1534/genetics.119.302262. PubMed PMID: 31092540; PMCID: PMC6614894.
Boos LA, Schmitt A, Moch H, Komminoth P, Simillion C, Marinoni I, Nikiforov YE, Nikiforova MN, Perren A, Dettmer MS. MiRNAs Are Involved in Tall Cell Morphology in Papillary Thyroid Carcinoma. Cancers (Basel). 2019-06-25;11(6): doi: 10.3390/cancers11060885. PubMed PMID: 31242620; PMCID: PMC6628239.
Griffith AS, Zhang TD, Burkert SC, Adiguzel Z, Acilan C, Star A, Saunders WS. Characterizing the Cellular Response to Nitrogen-Doped Carbon Nanocups. Nanomaterials (Basel). 2019-06-16;9(6): doi: 10.3390/nano9060887. PubMed PMID: 31208132; PMCID: PMC6631063.
Roy S, Agnihotri S, El Hallani S, Ernst WL, Wald AI, Santana Dos Santos L, Hamilton RL, Horbinski CM, Wadhwani NR, Born DE, Pollack IF, Nikiforov YE, Nikiforova MN. Clinical Utility of GlioSeq Next-Generation Sequencing Test in Pediatric and Young Adult Patients With Brain Tumors. J Neuropathol Exp Neurol. 2019-06-10; doi: 10.1093/jnen/nlz055. PubMed PMID: 31298284.
Wilkinson PD, Alencastro F, Delgado ER, Leek MP, Weirich MP, Otero PA, Roy N, Brown WK, Oertel M, Duncan AW. Polyploid Hepatocytes Facilitate Adaptation and Regeneration to Chronic Liver Injury. Am J Pathol. 2019-06-01;189(6):1241-1255. doi: 10.1016/j.ajpath.2019.02.008. PubMed PMID: 30928253; PMCID: PMC6547059.
Nechemia-Arbely Y, Miga KH, Shoshani O, Aslanian A, McMahon MA, Lee AY, Fachinetti D, Yates JR 3rd, Ren B, Cleveland DW. DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres. Nat Cell Biol. 2019-06-01;21(6):743-754. doi: 10.1038/s41556-019-0331-4. PubMed PMID: 31160708; PMCID: PMC7015266.
Singh M, Tian XJ, Donnenberg VS, Watson AM, Zhang J, Stabile LP, Watkins SC, Xing J, Sant S. Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration. Cancer Res. 2019-06-01;79(11):2962-2977. doi: 10.1158/0008-5472.CAN-18-3151. PubMed PMID: 30952634; PMCID: PMC6548579.
Mikulska-Ruminska K, Shrivastava I, Krieger J, Zhang S, Li H, Bayır H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I. Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members. J Chem Inf Model. 2019-05-28;59(5):2496-2508. doi: 10.1021/acs.jcim.9b00006. PubMed PMID: 30762363; PMCID: PMC6541894.
Luu HN, Qi M, Wang R, Adams-Haduch J, Miljkovic I, Opresko PL, Jin A, Koh WP, Yuan JM. Association Between Leukocyte Telomere Length and Colorectal Cancer Risk in the Singapore Chinese Health Study. Clin Transl Gastroenterol. 2019-05-22;10(5):1-9. doi: 10.14309/ctg.0000000000000043. PubMed PMID: 31117113; PMCID: PMC6602767.
Larsen MB, Perez Verdaguer M, Schmidt BF, Bruchez MP, Watkins SC, Sorkin A. Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis. Elife. 2019-05-08;8 doi: 10.7554/eLife.46135. PubMed PMID: 31066673; PMCID: PMC6533059.
Li M, Mandal A, Tyurin VA, DeLucia M, Ahn J, Kagan VE, van der Wel PCA. Surface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized Dynamics. Structure. 2019-05-07;27(5):806-815.e4. doi: 10.1016/j.str.2019.02.007. PubMed PMID: 30879887; PMCID: PMC6615723.
Braganza A, Quesnelle K, Bickta J, Reyes C, Wang Y, Jessup M, St Croix C, Arlotti J, Singh SV, Shiva S. Myoglobin induces mitochondrial fusion, thereby inhibiting breast cancer cell proliferation. J Biol Chem. 2019-05-03;294(18):7269-7282. doi: 10.1074/jbc.RA118.006673. PubMed PMID: 30872402; PMCID: PMC6509513.
Liang L, Chen V, Zhu K, Fan X, Lu X, Lu S. Integrating data and knowledge to identify functional modules of genes: a multilayer approach. BMC Bioinformatics. 2019-05-02;20(1):225. doi: 10.1186/s12859-019-2800-y. PubMed PMID: 31046665; PMCID: PMC6498600.
Chen D, Ni HM, Wang L, Ma X, Yu J, Ding WX, Zhang L. p53 Up-regulated Modulator of Apoptosis Induction Mediates Acetaminophen-Induced Necrosis and Liver Injury in Mice. Hepatology. 2019-05-01;69(5):2164-2179. doi: 10.1002/hep.30422. PubMed PMID: 30552702; PMCID: PMC6461480.
Veglia F, Tyurin VA, Blasi M, De Leo A, Kossenkov AV, Donthireddy L, To TKJ, Schug Z, Basu S, Wang F, Ricciotti E, DiRusso C, Murphy ME, Vonderheide RH, Lieberman PM, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Lin C, Nefedova Y, Black P, Kagan VE, Gabrilovich DI. Fatty acid transport protein 2 reprograms neutrophils in cancer. Nature. 2019-05-01;569(7754):73-78. doi: 10.1038/s41586-019-1118-2. PubMed PMID: 30996346; PMCID: PMC6557120.
Pisapia P, Malapelle U, Roma G, Saddar S, Zheng Q, Pepe F, Bruzzese D, Vigliar E, Bellevicine C, Luthra R, Nikiforov YE, Mayo-de-Las-Casas C, Molina-Vila MA, Rosell R, Bihl M, Savic S, Bubendorf L, de Biase D, Tallini G, Hwang DH, Sholl LM, Vander Borght S, Weynand B, Stieber D, Vielh P, Rappa A, Barberis M, Fassan M, Rugge M, De Andrea CE, Lozano MD, Lupi C, Fontanini G, Schmitt F, Dumur CI, Bisig B, Bongiovanni M, Merkelbach-Bruse S, Büttner R, Nikiforova MN, Roy-Chowdhuri S, Troncone G, Molecular Cytopathology Meeting Group.. Consistency and reproducibility of next-generation sequencing in cytopathology: A second worldwide ring trial study on improved cytological molecular reference specimens. Cancer Cytopathol. 2019-05-01;127(5):285-296. doi: 10.1002/cncy.22134. PubMed PMID: 31021538.
Fischer DK, Saito A, Kline C, Cohen R, Watkins SC, Yamashita M, Ambrose Z. CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes. J Virol. 2019-05-01;93(9): doi: 10.1128/JVI.00214-19. PubMed PMID: 30814280; PMCID: PMC6475785.
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Adamik J, Roodman GD, Galson DL. Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease. JBMR Plus. 2019-03-01;3(3):e10183. doi: 10.1002/jbm4.10183. PubMed PMID: 30918921; PMCID: PMC6419609.
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Zhang X, Fisher R, Shields D, Hou W, Franicola D, Wang H, Epperly MW, Rigatti L, Greenberger JS. Malignant Transformation of Fanconi Anemia Complementation Group D2-deficient (Fancd2 -/-) Hematopoietic Progenitor Cells by a Single HPV16 Oncogene. In Vivo. 2019-03-01;33(2):303-311. doi: 10.21873/invivo.11476. PubMed PMID: 30804107; PMCID: PMC6506306.
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Raza Q, Choi JY, Li Y, O'Dowd RM, Watkins SC, Chikina M, Hong Y, Clark NL, Kwiatkowski AV. Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila. PLoS Genet. 2019-02-01;15(2):e1007720. doi: 10.1371/journal.pgen.1007720. PubMed PMID: 30763317; PMCID: PMC6375579.
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Lee YS, Lee DH, Jeong SY, Park SH, Oh SC, Park YS, Yu J, Choudry HA, Bartlett DL, Lee YJ. Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5. J Cell Biochem. 2019-01-01;120(1):928-939. doi: 10.1002/jcb.27456. PubMed PMID: 30160785; PMCID: PMC6249082.
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Fouquerel E, Barnes RP, Wang H, Opresko PL. Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA. Methods Mol Biol. 2019-01-01;1999295-306. doi: 10.1007/978-1-4939-9500-4_20. PubMed PMID: 31127586; PMCID: PMC6886745.
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Qin Y, Vasilatos SN, Chen L, Wu H, Cao Z, Fu Y, Huang M, Vlad AM, Lu B, Oesterreich S, Davidson NE, Huang Y. Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade. Oncogene. 2019-01-01;38(3):390-405. doi: 10.1038/s41388-018-0451-5. PubMed PMID: 30111819; PMCID: PMC6336685.
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Anthonymuthu TS, Kenny EM, Shrivastava I, Tyurina YY, Hier ZE, Ting HC, Dar HH, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Zhao J, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayır H. Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE. J Am Chem Soc. 2018-12-26;140(51):17835-17839. doi: 10.1021/jacs.8b09913. PubMed PMID: 30525572; PMCID: PMC6622169.
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Bakkenist CJ, Lee JJ, Schmitz JC. ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer. Clin Colorectal Cancer. 2018-12-01;17(4):255-257. doi: 10.1016/j.clcc.2018.09.001. PubMed PMID: 30316683; PMCID: PMC6561466.
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Zhang J, Zhang S, Liu Y, Su M, Ling X, Liu F, Ge Y, Bai M. Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer. Photodiagnosis Photodyn Ther. 2018-12-01;24185-191. doi: 10.1016/j.pdpdt.2018.09.006. PubMed PMID: 30240926; PMCID: PMC6289793.
Pabon NA, Xia Y, Estabrooks SK, Ye Z, Herbrand AK, Süß E, Biondi RM, Assimon VA, Gestwicki JE, Brodsky JL, Camacho CJ, Bar-Joseph Z. Predicting protein targets for drug-like compounds using transcriptomics. PLoS Comput Biol. 2018-12-01;14(12):e1006651. doi: 10.1371/journal.pcbi.1006651. PubMed PMID: 30532261; PMCID: PMC6300300.
Yang F, Wang F, Liu Y, Wang S, Li X, Huang Y, Xia Y, Cao C. Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells. Life Sci. 2018-11-15;213149-157. doi: 10.1016/j.lfs.2018.10.034. PubMed PMID: 30352240.
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Adamik J, Galson DL, Roodman GD. Osteoblast suppression in multiple myeloma bone disease. J Bone Oncol. 2018-11-01;1362-70. doi: 10.1016/j.jbo.2018.09.001. PubMed PMID: 30591859; PMCID: PMC6303385.
Nikitski AV, Rominski SL, Wankhede M, Kelly LM, Panebianco F, Barila G, Altschuler DL, Nikiforov YE. Mouse Model of Poorly Differentiated Thyroid Carcinoma Driven by STRN-ALK Fusion. Am J Pathol. 2018-11-01;188(11):2653-2661. doi: 10.1016/j.ajpath.2018.07.012. PubMed PMID: 30125543; PMCID: PMC6222272.
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Tong J, Wang P, Tan S, Chen D, Nikolovska-Coleska Z, Zou F, Yu J, Zhang L. Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells. Cancer Res. 2017-05-01;77(9):2512-2521. doi: 10.1158/0008-5472.CAN-16-3242. PubMed PMID: 28202514; PMCID: PMC5626525.
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