Publications

Preclinical%20Discovery%20/%20Development%20of%20Novel%20Targets%20/%20Pathways%20and%20Novel%20Agents

Bardhan A, Brown W, Albright S, Tsang M, Davidson L, Deiters A. Direct Activation of Nucleobases with Small Molecules for the Conditional Control of Antisense Function. Angew Chem Int Ed Engl. 2024-04-22;e202318773. doi: 10.1002/anie.202318773. PubMed PMID: 38411401.
Butrovich MA, Qin J, Xue X, Ivy SP, Nolin TD, Beumer JH. Impact of the 2021 CKD-EPI equation on anticancer pharmacotherapy in black and non-black cancer patients. Cancer Lett. 2024-04-01;216679. doi: 10.1016/j.canlet.2024.216679. PubMed PMID: 38307411; PMCID: PMC10939791.
Hertz DL, Joerger M, Bang YJ, Mathijssen RH, Zhou C, Zhang L, Gandara D, Stahl M, Monk BJ, Jaehde U, Beumer JH. Paclitaxel therapeutic drug monitoring - International association of therapeutic drug monitoring and clinical toxicology recommendations. Eur J Cancer. 2024-03-19;202114024. doi: 10.1016/j.ejca.2024.114024. PubMed PMID: 38513383.
Chen Y, Chen CY, Huang H, Luo Z, Mu Y, Li S, Li S. Knocking down of Xkr8 enhances chemotherapy efficacy through modulating tumor immune microenvironment. J Control Release. 2024-03-10; doi: 10.1016/j.jconrel.2024.03.011. PubMed PMID: 38471639.
Xu P, Xi Y, Kim JW, Zhu J, Zhang M, Xu M, Ren S, Yang D, Ma X, Xie W. Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis. Acta Pharm Sin B. 2024-03-01;14(3):1241-1256. doi: 10.1016/j.apsb.2023.12.006. PubMed PMID: 38487006; PMCID: PMC10935170.
Chao Y, Chen Y, Zheng W, Demanelis K, Liu Y, Connelly JA, Wang H, Li S, Wang QJ. Synthetic lethal combination of CHK1 and WEE1 inhibition for treatment of castration-resistant prostate cancer. Oncogene. 2024-03-01; doi: 10.1038/s41388-024-02939-z. PubMed PMID: 38273024.
Beumer JH, Salamone SJ. Project Confirm: Accelerated Drug Approvals for CML-Letter. Clin Cancer Res. 2024-01-05;30(1):235-236. doi: 10.1158/1078-0432.CCR-23-2630. PubMed PMID: 38178775; PMCID: PMC10783536.
Luo Z, Huang Y, Batra N, Chen Y, Huang H, Wang Y, Zhang Z, Li S, Chen CY, Wang Z, Sun J, Wang QJ, Yang D, Lu B, Conway JF, Li LY, Yu AM, Li S. Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy. Nat Commun. 2024-01-04;15(1):255. doi: 10.1038/s41467-023-44572-6. PubMed PMID: 38177179; PMCID: PMC10766965.
Beard JP, Bressin RK, Markaj PL, Schmitz JC, Koide K. Synthesis and Conformational Analysis of FR901464-Based RNA Splicing Modulators and Their Synergism in Drug-Resistant Cancers. J Med Chem. 2023-11-09; doi: 10.1021/acs.jmedchem.3c00733. PubMed PMID: 37870431; PMCID: PMC10641826.
Xu P, Cai X, Guan X, Xie W. Sulfoconjugation of protein peptides and glycoproteins in physiology and diseases. Pharmacol Ther. 2023-11-01;108540. doi: 10.1016/j.pharmthera.2023.108540. PubMed PMID: 37777160; PMCID: PMC10842354.
Albright S, Cacace M, Tivon Y, Deiters A. Cell Surface Labeling and Detection of Protein Tyrosine Kinase 7 via Covalent Aptamers. J Am Chem Soc. 2023-08-02;145(30):16458-16463. doi: 10.1021/jacs.3c02752. PubMed PMID: 37473438; PMCID: PMC10401710.
Brown W, Wesalo J, Tsang M, Deiters A. Engineering Small Molecule Switches of Protein Function in Zebrafish Embryos. J Am Chem Soc. 2023-02-01;145(4):2395-2403. doi: 10.1021/jacs.2c11366. PubMed PMID: 36662675.
Chen Y, Huang Y, Li Q, Luo Z, Zhang Z, Huang H, Sun J, Zhang L, Sun R, Bain DJ, Conway JF, Lu B, Li S. Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy. Nat Nanotechnol. 2023-02-01;18(2):193-204. doi: 10.1038/s41565-022-01266-2. PubMed PMID: 36424448; PMCID: PMC9974593.
Brown W, Galpin JD, Rosenblum C, Tsang M, Ahern CA, Deiters A. Chemically Acylated tRNAs are Functional in Zebrafish Embryos. J Am Chem Soc. 2023-02-01;145(4):2414-2420. doi: 10.1021/jacs.2c11452. PubMed PMID: 36669466; PMCID: PMC10155198.
Pizzoni A, Zhang X, Naim N, Altschuler DL. Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation. Proc Natl Acad Sci U S A. 2023-01-24;120(4):e2208749120. doi: 10.1073/pnas.2208749120. PubMed PMID: 36656863; PMCID: PMC9942871.
Zhang Y, Li J, Huang Y, Chen Y, Luo Z, Huang H, West RE 3rd, Nolin TD, Wang Z, Li S. Improved antitumor activity against prostate cancer via synergistic targeting of Myc and GFAT-1. Theranostics. 2023-01-01;13(2):578-595. doi: 10.7150/thno.76614. PubMed PMID: 36632215; PMCID: PMC9830436.
Emanuelson C, Ankenbruck N, Kumbhare R, Thomas M, Connelly C, Baktash Y, Randall G, Deiters A. Transcriptional Inhibition of MicroRNA miR-122 by Small Molecules Reduces Hepatitis C Virus Replication in Liver Cells. J Med Chem. 2022-12-22;65(24):16338-16352. doi: 10.1021/acs.jmedchem.2c01141. PubMed PMID: 36449366; PMCID: PMC9942140.
Atiya HI, Frisbie L, Goldfeld E, Orellana T, Donnellan N, Modugno F, Calderon M, Watkins S, Zhang R, Elishaev E, Soong TR, Vlad A, Coffman L. Endometriosis-Associated Mesenchymal Stem Cells Support Ovarian Clear Cell Carcinoma through Iron Regulation. Cancer Res. 2022-12-16;82(24):4680-4693. doi: 10.1158/0008-5472.CAN-22-1294. PubMed PMID: 36219681; PMCID: PMC9755968.
Beumer JH, Chu E, Salamone SJ. All Optimal Dosing Roads Lead to Therapeutic Drug Monitoring-Why Take the Slow Lane. JAMA Oncol. 2022-12-01;8(12):1733-1735. doi: 10.1001/jamaoncol.2022.4452. PubMed PMID: 36264552; PMCID: PMC9772116.
Brown W, Bardhan A, Darrah K, Tsang M, Deiters A. Optical Control of MicroRNA Function in Zebrafish Embryos. J Am Chem Soc. 2022-09-21;144(37):16819-16826. doi: 10.1021/jacs.2c04479. PubMed PMID: 36073798.
Xu P, Xi Y, Wang P, Luka Z, Xu M, Tung HC, Wang J, Ren S, Feng D, Gao B, Singhi AD, Monga SP, York JD, Ma X, Huang Z, Xie W. Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure. Gastroenterology. 2022-04-01;162(4):1226-1241. doi: 10.1053/j.gastro.2021.12.260. PubMed PMID: 34954226; PMCID: PMC8934304.
Moharil P, Wan Z, Pardeshi A, Li J, Huang H, Luo Z, Rathod S, Zhang Z, Chen Y, Zhang B, Fernandez CA, Sun J, Li S. Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy: Dual targeting of tumor cells and tumor-associated macrophages. Acta Pharm Sin B. 2022-03-01;12(3):1148-1162. doi: 10.1016/j.apsb.2021.09.024. PubMed PMID: 35530140; PMCID: PMC9072252.
Wan Z, Sun R, Liu YW, Li S, Sun J, Li J, Zhu J, Moharil P, Zhang B, Ren P, Ren G, Zhang M, Ma X, Dai S, Yang D, Lu B, Li S. Targeting metabotropic glutamate receptor 4 for cancer immunotherapy. Sci Adv. 2021-12-10;7(50):eabj4226. doi: 10.1126/sciadv.abj4226. PubMed PMID: 34890233; PMCID: PMC8664261.
Darrah KE, Deiters A. Translational control of gene function through optically regulated nucleic acids. Chem Soc Rev. 2021-11-29;50(23):13253-13267. doi: 10.1039/d1cs00257k. PubMed PMID: 34739027; PMCID: PMC8900068.
Darrah K, Wesalo J, Lukasak B, Tsang M, Chen JK, Deiters A. Small Molecule Control of Morpholino Antisense Oligonucleotide Function through Staudinger Reduction. J Am Chem Soc. 2021-11-10;143(44):18665-18671. doi: 10.1021/jacs.1c08723. PubMed PMID: 34705461; PMCID: PMC9014490.
Burrows J, Kamo S, Koide K. Scalable Birch reduction with lithium and ethylenediamine in tetrahydrofuran. Science. 2021-11-05;374(6568):741-746. doi: 10.1126/science.abk3099. PubMed PMID: 34735232.
Xi Y, Li Y, Xu P, Li S, Liu Z, Tung HC, Cai X, Wang J, Huang H, Wang M, Xu M, Ren S, Li S, Zhang M, Lee YJ, Huang L, Yang D, He J, Huang Z, Xie W. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021-09-03;7(36):eabg9241. doi: 10.1126/sciadv.abg9241. PubMed PMID: 34516906; PMCID: PMC8442864.
Tivon Y, Falcone G, Deiters A. Protein Labeling and Crosslinking by Covalent Aptamers. Angew Chem Int Ed Engl. 2021-07-12;60(29):15899-15904. doi: 10.1002/anie.202101174. PubMed PMID: 33928724; PMCID: PMC8260448.
Xu P, Xi Y, Zhu J, Zhang M, Luka Z, Stolz DB, Cai X, Xie Y, Xu M, Ren S, Huang Z, Yang D, York JD, Ma X, Xie W. Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. Gastroenterology. 2021-07-01;161(1):271-286.e11. doi: 10.1053/j.gastro.2021.03.048. PubMed PMID: 33819483; PMCID: PMC8238844.
Colen RR, Rolfo C, Ak M, Ayoub M, Ahmed S, Elshafeey N, Mamindla P, Zinn PO, Ng C, Vikram R, Bakas S, Peterson CB, Rodon Ahnert J, Subbiah V, Karp DD, Stephen B, Hajjar J, Naing A. Author response to Cunha et al. J Immunother Cancer. 2021-07-01;9(7): doi: 10.1136/jitc-2021-003299. PubMed PMID: 34315823; PMCID: PMC8317086.
Ryan A, Liu J, Deiters A. Targeted Protein Degradation through Fast Optogenetic Activation and Its Application to the Control of Cell Signaling. J Am Chem Soc. 2021-06-23;143(24):9222-9229. doi: 10.1021/jacs.1c04324. PubMed PMID: 34121391.
Zhang X, Pizzoni A, Hong K, Naim N, Qi C, Korkhov V, Altschuler DL. CAP1 binds and activates adenylyl cyclase in mammalian cells. Proc Natl Acad Sci U S A. 2021-06-15;118(24): doi: 10.1073/pnas.2024576118. PubMed PMID: 34099549; PMCID: PMC8214675.
Camidge DR, Otterson GA, Clark JW, Ignatius Ou SH, Weiss J, Ades S, Shapiro GI, Socinski MA, Murphy DA, Conte U, Tang Y, Wang SC, Wilner KD, Villaruz LC. Crizotinib in Patients With MET-Amplified NSCLC. J Thorac Oncol. 2021-06-01;16(6):1017-1029. doi: 10.1016/j.jtho.2021.02.010. PubMed PMID: 33676017.
Gough A, Soto-Gutierrez A, Vernetti L, Ebrahimkhani MR, Stern AM, Taylor DL. Human biomimetic liver microphysiology systems in drug development and precision medicine. Nat Rev Gastroenterol Hepatol. 2021-04-01;18(4):252-268. doi: 10.1038/s41575-020-00386-1. PubMed PMID: 33335282; PMCID: PMC9106093.
Colen RR, Rolfo C, Ak M, Ayoub M, Ahmed S, Elshafeey N, Mamindla P, Zinn PO, Ng C, Vikram R, Bakas S, Peterson CB, Rodon Ahnert J, Subbiah V, Karp DD, Stephen B, Hajjar J, Naing A. Radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers. J Immunother Cancer. 2021-04-01;9(4): doi: 10.1136/jitc-2020-001752. PubMed PMID: 33849924; PMCID: PMC8051405.
Huang H, Huang Y, Chen Y, Luo Z, Zhang Z, Sun R, Wan Z, Sun J, Lu B, Zhang L, Hu J, Li S. A novel immunochemotherapy based on targeting of cyclooxygenase and induction of immunogenic cell death. Biomaterials. 2021-03-01;270120708. doi: 10.1016/j.biomaterials.2021.120708. PubMed PMID: 33578254; PMCID: PMC7910750.
Cai X, Feng Y, Xu M, Yu C, Xie W. Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR). Acta Pharm Sin B. 2021-02-01;11(2):434-441. doi: 10.1016/j.apsb.2020.08.015. PubMed PMID: 33643822; PMCID: PMC7893119.
Sun J, Wan Z, Xu J, Luo Z, Ren P, Zhang B, Diao D, Huang Y, Li S. Tumor size-dependent abscopal effect of polydopamine-coated all-in-one nanoparticles for immunochemo-photothermal therapy of early- and late-stage metastatic cancer. Biomaterials. 2021-02-01;269120629. doi: 10.1016/j.biomaterials.2020.120629. PubMed PMID: 33387938; PMCID: PMC8466812.
Darrah K, Deiters A. Targeted Drug Delivery through Optical Control of Cell Lysis. ACS Cent Sci. 2021-01-27;7(1):11-13. doi: 10.1021/acscentsci.0c01562. PubMed PMID: 33532563; PMCID: PMC7844846.
Pham D, Deter CJ, Reinard MC, Gibson GA, Kiselyov K, Yu W, Sandulache VC, St Croix CM, Koide K. Using Ligand-Accelerated Catalysis to Repurpose Fluorogenic Reactions for Platinum or Copper. ACS Cent Sci. 2020-10-28;6(10):1772-1788. doi: 10.1021/acscentsci.0c00676. PubMed PMID: 33145414; PMCID: PMC7596870.
Fang Z, Wang Y, Wang Z, Xu M, Ren S, Yang D, Hong M, Xie W. ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway. Cancer Res. 2020-10-15;80(20):4399-4413. doi: 10.1158/0008-5472.CAN-20-1031. PubMed PMID: 32826278; PMCID: PMC7572695.
Pham D, Basu U, Pohorilets I, St Croix CM, Watkins SC, Koide K. Fluorogenic Probe Using a Mislow-Evans Rearrangement for Real-Time Imaging of Hydrogen Peroxide. Angew Chem Int Ed Engl. 2020-09-28;59(40):17435-17441. doi: 10.1002/anie.202007104. PubMed PMID: 32585075.
Silva Barbosa AC, Zhou D, Xie Y, Choi YJ, Tung HC, Chen X, Xu M, Gibbs RB, Poloyac SM, Liu S, Yu Y, Luo J, Liu Y, Xie W. Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice. J Am Soc Nephrol. 2020-07-01;31(7):1496-1508. doi: 10.1681/ASN.2019080767. PubMed PMID: 32424001; PMCID: PMC7351010.
Zhou W, Brown W, Bardhan A, Delaney M, Ilk AS, Rauen RR, Kahn SI, Tsang M, Deiters A. Spatiotemporal Control of CRISPR/Cas9 Function in Cells and Zebrafish using Light-Activated Guide RNA. Angew Chem Int Ed Engl. 2020-06-02;59(23):8998-9003. doi: 10.1002/anie.201914575. PubMed PMID: 32160370; PMCID: PMC7250724.
Somasundaram A, Socinski MA, Villaruz LC. Immune Checkpoint Blockade in Oncogene-Driven Non-Small-Cell Lung Cancer. Drugs. 2020-06-01;80(9):883-892. doi: 10.1007/s40265-020-01320-0. PubMed PMID: 32436070; PMCID: PMC8579493.
Sun J, Wan Z, Chen Y, Xu J, Luo Z, Parise RA, Diao D, Ren P, Beumer JH, Lu B, Li S. Triple drugs co-delivered by a small gemcitabine-based carrier for pancreatic cancer immunochemotherapy. Acta Biomater. 2020-04-01;106289-300. doi: 10.1016/j.actbio.2020.01.039. PubMed PMID: 32004652; PMCID: PMC7183357.
Luo Z, Xu J, Sun J, Huang H, Zhang Z, Ma W, Wan Z, Liu Y, Pardeshi A, Li S. Co-delivery of 2-Deoxyglucose and a glutamine metabolism inhibitor V9302 via a prodrug micellar formulation for synergistic targeting of metabolism in cancer. Acta Biomater. 2020-03-15;105239-252. doi: 10.1016/j.actbio.2020.01.019. PubMed PMID: 31958597; PMCID: PMC7105957.
Naro Y, Darrah K, Deiters A. Optical Control of Small Molecule-Induced Protein Degradation. J Am Chem Soc. 2020-02-05;142(5):2193-2197. doi: 10.1021/jacs.9b12718. PubMed PMID: 31927988; PMCID: PMC7229639.
Ma W, Sun J, Xu J, Luo Z, Diao D, Zhang Z, Oberly PJ, Minnigh MB, Xie W, Poloyac SM, Huang Y, Li S. Sensitizing Triple Negative Breast Cancer to Tamoxifen Chemotherapy via a Redox-Responsive Vorinostat-containing Polymeric Prodrug Nanocarrier. Theranostics. 2020-01-20;10(6):2463-2478. doi: 10.7150/thno.38973. PubMed PMID: 32194813; PMCID: PMC7052901.
Sun J, Chen Y, Xu J, Song X, Wan Z, Du Y, Ma W, Li X, Zhang L, Li S. High Loading of Hydrophobic and Hydrophilic Agents via Small Immunostimulatory Carrier for Enhanced Tumor Penetration and Combinational Therapy. Theranostics. 2020-01-01;10(3):1136-1150. doi: 10.7150/thno.38287. PubMed PMID: 31938056; PMCID: PMC6956803.
Xie W. Editorial of Special Issue on Drug Metabolism and Disposition in Diseases. Acta Pharm Sin B. 2020-01-01;10(1):2. doi: 10.1016/j.apsb.2019.12.016. PubMed PMID: 31993303; PMCID: PMC6977160.
Wang Y, Fang Z, Hong M, Yang D, Xie W. Long-noncoding RNAs (lncRNAs) in drug metabolism and disposition, implications in cancer chemo-resistance. Acta Pharm Sin B. 2020-01-01;10(1):105-112. doi: 10.1016/j.apsb.2019.09.011. PubMed PMID: 31993309; PMCID: PMC6976993.
Courtney TM, Deiters A. Optical control of protein phosphatase function. Nat Commun. 2019-09-26;10(1):4384. doi: 10.1038/s41467-019-12260-z. PubMed PMID: 31558717; PMCID: PMC6763421.
Yan J, Tung HC, Li S, Niu Y, Garbacz WG, Lu P, Bi Y, Li Y, He J, Xu M, Ren S, Monga SP, Schwabe RF, Yang D, Xie W. Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice. Gastroenterology. 2019-09-01;157(3):793-806.e14. doi: 10.1053/j.gastro.2019.05.066. PubMed PMID: 31170413; PMCID: PMC6707837.
Xie Y, Xu M, Deng M, Li Z, Wang P, Ren S, Guo Y, Ma X, Fan J, Billiar TR, Xie W. Activation of Pregnane X Receptor Sensitizes Mice to Hemorrhagic Shock-Induced Liver Injury. Hepatology. 2019-09-01;70(3):995-1010. doi: 10.1002/hep.30691. PubMed PMID: 31038762; PMCID: PMC6717545.
Elshafeey N, Kotrotsou A, Hassan A, Elshafei N, Hassan I, Ahmed S, Abrol S, Agarwal A, El Salek K, Bergamaschi S, Acharya J, Moron FE, Law M, Fuller GN, Huse JT, Zinn PO, Colen RR. Multicenter study demonstrates radiomic features derived from magnetic resonance perfusion images identify pseudoprogression in glioblastoma. Nat Commun. 2019-07-18;10(1):3170. doi: 10.1038/s41467-019-11007-0. PubMed PMID: 31320621; PMCID: PMC6639324.
Xu J, Sun J, Ho PY, Luo Z, Ma W, Zhao W, Rathod SB, Fernandez CA, Venkataramanan R, Xie W, Yu AM, Li S. Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis. Biomaterials. 2019-07-01;21025-40. doi: 10.1016/j.biomaterials.2019.04.025. PubMed PMID: 31054369; PMCID: PMC6538300.
Wan Z, Sun J, Xu J, Moharil P, Chen J, Xu J, Zhu J, Li J, Huang Y, Xu P, Ma X, Xie W, Lu B, Li S. Dual functional immunostimulatory polymeric prodrug carrier with pendent indoximod for enhanced cancer immunochemotherapy. Acta Biomater. 2019-05-01;90300-313. doi: 10.1016/j.actbio.2019.03.048. PubMed PMID: 30930305; PMCID: PMC6513707.
Clump DA, Pickering CR, Skinner HD. Predicting Outcome in Head and Neck Cancer: miRNAs with Potentially Big Effects. Clin Cancer Res. 2019-03-01;25(5):1441-1442. doi: 10.1158/1078-0432.CCR-18-3078. PubMed PMID: 30413524; PMCID: PMC6415532.
Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV, Barkardottir RB, Barnes DR, Batra J, Beckmann MW, Benitez J, Benlloch S, Berchuck A, Berndt SI, Bickeböller H, Bien SA, Blomqvist C, Boccia S, Bogdanova NV, Bojesen SE, Bolla MK, Brauch H, Brenner H, Brenton JD, Brook MN, Brunet J, Brunnström H, Buchanan DD, Burwinkel B, Butzow R, Cadoni G, Caldés T, Caligo MA, Campbell I, Campbell PT, Cancel-Tassin G, Cannon-Albright L, Campa D, Caporaso N, Carvalho AL, Chan AT, Chang-Claude J, Chanock SJ, Chen C, Christiani DC, Claes KBM, Claessens F, Clements J, Collée JM, Correa MC, Couch FJ, Cox A, Cunningham JM, Cybulski C, Czene K, Daly MB, deFazio A, Devilee P, Diez O, Gago-Dominguez M, Donovan JL, Dörk T, Duell EJ, Dunning AM, Dwek M, Eccles DM, Edlund CK, Edwards DRV, Ellberg C, Evans DG, Fasching PA, Ferris RL, Liloglou T, Figueiredo JC, Fletcher O, Fortner RT, Fostira F, Franceschi S, Friedman E, Gallinger SJ, Ganz PA, Garber J, García-Sáenz JA, Gayther SA, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, Goode EL, Goodman MT, Goodman G, Grankvist K, Greene MH, Gronberg H, Gronwald J, Guénel P, Håkansson N, Hall P, Hamann U, Hamdy FC, Hamilton RJ, Hampe J, Haugen A, Heitz F, Herrero R, Hillemanns P, Hoffmeister M, Høgdall E, Hong YC, Hopper JL, Houlston R, Hulick PJ, Hunter DJ, Huntsman DG, Idos G, Imyanitov EN, Ingles SA, Isaacs C, Jakubowska A, James P, Jenkins MA, Johansson M, Johansson M, John EM, Joshi AD, Kaneva R, Karlan BY, Kelemen LE, Kühl T, Khaw KT, Khusnutdinova E, Kibel AS, Kiemeney LA, Kim J, Kjaer SK, Knight JA, Kogevinas M, Kote-Jarai Z, Koutros S, Kristensen VN, Kupryjanczyk J, Lacko M, Lam S, Lambrechts D, Landi MT, Lazarus P, Le ND, Lee E, Lejbkowicz F, Lenz HJ, Leslie G, Lessel D, Lester J, Levine DA, Li L, Li CI, Lindblom A, Lindor NM, Liu G, Loupakis F, Lubiński J, Maehle L, Maier C, Mannermaa A, Marchand LL, Margolin S, May T, McGuffog L, Meindl A, Middha P, Miller A, Milne RL, MacInnis RJ, Modugno F, Montagna M, Moreno V, Moysich KB, Mucci L, Muir K, Mulligan AM, Nathanson KL, Neal DE, Ness AR, Neuhausen SL, Nevanlinna H, Newcomb PA, Newcomb LF, Nielsen FC, Nikitina-Zake L, Nordestgaard BG, Nussbaum RL, Offit K, Olah E, Olama AAA, Olopade OI, Olshan AF, Olsson H, Osorio A, Pandha H, Park JY, Pashayan N, Parsons MT, Pejovic T, Penney KL, Peters WHM, Phelan CM, Phipps AI, Plaseska-Karanfilska D, Pring M, Prokofyeva D, Radice P, Stefansson K, Ramus SJ, Raskin L, Rennert G, Rennert HS, van Rensburg EJ, Riggan MJ, Risch HA, Risch A, Roobol MJ, Rosenstein BS, Rossing MA, De Ruyck K, Saloustros E, Sandler DP, Sawyer EJ, Schabath MB, Schleutker J, Schmidt MK, Setiawan VW, Shen H, Siegel EM, Sieh W, Singer CF, Slattery ML, Sorensen KD, Southey MC, Spurdle AB, Stanford JL, Stevens VL, Stintzing S, Stone J, Sundfeldt K, Sutphen R, Swerdlow AJ, Tajara EH, Tangen CM, Tardon A, Taylor JA, Teare MD, Teixeira MR, Terry MB, Terry KL, Thibodeau SN, Thomassen M, Bjørge L, Tischkowitz M, Toland AE, Torres D, Townsend PA, Travis RC, Tung N, Tworoger SS, Ulrich CM, Usmani N, Vachon CM, Van Nieuwenhuysen E, Vega A, Aguado-Barrera ME, Wang Q, Webb PM, Weinberg CR, Weinstein S, Weissler MC, Weitzel JN, West CML, White E, Whittemore AS, Wichmann HE, Wiklund F, Winqvist R, Wolk A, Woll P, Woods M, Wu AH, Wu X, Yannoukakos D, Zheng W, Zienolddiny S, Ziogas A, Zorn KK, Lane JM, Saxena R, Thomas D, Hung RJ, Diergaarde B, McKay J, Peters U, Hsu L, García-Closas M, Eeles RA, Chenevix-Trench G, Brennan PJ, Haiman CA, Simard J, Easton DF, Gruber SB, Pharoah PDP, Price AL, Pasaniuc B, Amos CI, Kraft P, Lindström S. Shared heritability and functional enrichment across six solid cancers. Nat Commun. 2019-01-25;10(1):431. doi: 10.1038/s41467-018-08054-4. PubMed PMID: 30683880; PMCID: PMC6347624.
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