Publications

Joseph Glorioso

Wirsching HG, Arora S, Zhang H, Szulzewsky F, Cimino PJ, Quéva C, Houghton AM, Glorioso JC, Weller M, Holland EC. Cooperation of oncolytic virotherapy with VEGF-neutralizing antibody treatment in IDH wildtype glioblastoma depends on MMP9. Neuro Oncol. 2019 Dec 17;21(12):1607-1609. doi: 10.1093/neuonc/noz145. PubMed PMID: 31412117; PMCID: PMC6917394.
Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019 Jul 11;4(13): doi: 10.1172/jci.insight.128217. PubMed PMID: 31292299; PMCID: PMC6629248.
Artusi S, Miyagawa Y, Goins WF, Cohen JB, Glorioso JC. Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System. Diseases. 2018 Aug 14;6(3): doi: 10.3390/diseases6030074. PubMed PMID: 30110885; PMCID: PMC6164475.
Han F, Miyagawa Y, Verlengia G, Ingusci S, Soukupova M, Simonato M, Glorioso JC, Cohen JB. Cellular Antisilencing Elements Support Transgene Expression from Herpes Simplex Virus Vectors in the Absence of Immediate Early Gene Expression. J Virol. 2018 Sep 1;92(17): doi: 10.1128/JVI.00536-18. PubMed PMID: 29950408; PMCID: PMC6096828.
Miyagawa Y, Verlengia G, Reinhart B, Han F, Uchida H, Zucchini S, Goins WF, Simonato M, Cohen JB, Glorioso JC. Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes. Mol Ther Methods Clin Dev. 2017 Sep 15;679-90. doi: 10.1016/j.omtm.2017.06.001. PubMed PMID: 28702475; PMCID: PMC5493822.
Verlengia G, Miyagawa Y, Ingusci S, Cohen JB, Simonato M, Glorioso JC. Engineered HSV vector achieves safe long-term transgene expression in the central nervous system. Sci Rep. 2017 May 4;7(1):1507. doi: 10.1038/s41598-017-01635-1. PubMed PMID: 28473703; PMCID: PMC5431452.
Uchida H, Hamada H, Nakano K, Kwon H, Tahara H, Cohen JB, Glorioso JC. Oncolytic Herpes Simplex Virus Vectors Fully Retargeted to Tumor- Associated Antigens. Curr Cancer Drug Targets. 2018;18(2):162-170. doi: 10.2174/1568009617666170206105855. PubMed PMID: 28176649.
Okubo Y, Uchida H, Wakata A, Suzuki T, Shibata T, Ikeda H, Yamaguchi M, Cohen JB, Glorioso JC, Tagaya M, Hamada H, Tahara H. Syncytial Mutations Do Not Impair the Specificity of Entry and Spread of a Glycoprotein D Receptor-Retargeted Herpes Simplex Virus. J Virol. 2016 Dec 15;90(24):11096-11105. doi: 10.1128/JVI.01456-16. PubMed PMID: 27707922; PMCID: PMC5126368.
Goins WF, Hall B, Cohen JB, Glorioso JC. Retargeting of herpes simplex virus (HSV) vectors. Curr Opin Virol. 2016 Dec;2193-101. doi: 10.1016/j.coviro.2016.08.007. PubMed PMID: 27614209; PMCID: PMC5138136.
Reinhart B, Goins WF, Harel A, Chaudhry S, Goss JR, Yoshimura N, de Groat WC, Cohen JB, Glorioso JC. An HSV-based library screen identifies PP1α as a negative TRPV1 regulator with analgesic activity in models of pain. Mol Ther Methods Clin Dev. 2016;316040. doi: 10.1038/mtm.2016.40. PubMed PMID: 27382601; PMCID: PMC4916946.
Han J, Chu J, Keung Chan W, Zhang J, Wang Y, Cohen JB, Victor A, Meisen WH, Kim SH, Grandi P, Wang QE, He X, Nakano I, Chiocca EA, Glorioso Iii JC, Kaur B, Caligiuri MA, Yu J. CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells. Sci Rep. 2015 Jul 9;511483. doi: 10.1038/srep11483. PubMed PMID: 26155832; PMCID: PMC4496728.
Guedon JM, Wu S, Zheng X, Churchill CC, Glorioso JC, Liu CH, Liu S, Vulchanova L, Bekker A, Tao YX, Kinchington PR, Goins WF, Fairbanks CA, Hao S. Current gene therapy using viral vectors for chronic pain. Mol Pain. 2015 May 13;1127. doi: 10.1186/s12990-015-0018-1. PubMed PMID: 25962909; PMCID: PMC4446851.
Miyagawa Y, Marino P, Verlengia G, Uchida H, Goins WF, Yokota S, Geller DA, Yoshida O, Mester J, Cohen JB, Glorioso JC. Herpes simplex viral-vector design for efficient transduction of nonneuronal cells without cytotoxicity. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1632-41. doi: 10.1073/pnas.1423556112. PubMed PMID: 25775541; PMCID: PMC4386379.
Leddon JL, Chen CY, Currier MA, Wang PY, Jung FA, Denton NL, Cripe KM, Haworth KB, Arnold MA, Gross AC, Eubank TD, Goins WF, Glorioso JC, Cohen JB, Grandi P, Hildeman DA, Cripe TP. Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity. Mol Ther Oncolytics. 2015;114010. doi: 10.1038/mto.2014.10. PubMed PMID: 27119100; PMCID: PMC4782947.

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