Publications

Walter Storkus

Hao X, Falo Iii LD, Chen G, Zhang J, Carey CD, Storkus WJ, Falo LD Jr, You Z. Skin immunization for effective treatment of multifocal melanoma refractory to PD1 blockade and Braf inhibitors. J Immunother Cancer. 2021 Jan;9(1): doi: 10.1136/jitc-2020-001179. PubMed PMID: 33408093; PMCID: PMC7789470.
Close DA, Kirkwood JM, Fecek RJ, Storkus WJ, Johnston PA. Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines. SLAS Discov. 2021 Jun;26(5):712-729. doi: 10.1177/2472555220970917. PubMed PMID: 33208016; PMCID: PMC8128935.
Maurer DM, Adamik J, Santos PM, Shi J, Shurin MR, Kirkwood JM, Storkus WJ, Butterfield LH. Dysregulated NF-κB-Dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Patients with Melanoma. Cancer Immunol Res. 2020 Dec;8(12):1554-1567. doi: 10.1158/2326-6066.CIR-20-0274. PubMed PMID: 33051240; PMCID: PMC8018573.
Razzo BM, Ludwig N, Hong CS, Sharma P, Fabian KP, Fecek RJ, Storkus WJ, Whiteside TL. Tumor-derived exosomes promote carcinogenesis of murine oral squamous cell carcinoma. Carcinogenesis. 2020 Jul 10;41(5):625-633. doi: 10.1093/carcin/bgz124. PubMed PMID: 31245809; PMCID: PMC7350555.
Ludwig S, Hong CS, Razzo BM, Fabian KPL, Chelvanambi M, Lang S, Storkus WJ, Whiteside TL. Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma. Cancer Immunol Immunother. 2019 Jul;68(7):1133-1141. doi: 10.1007/s00262-019-02348-2. PubMed PMID: 31139925.
Russell KL, Gorgulho CM, Allen A, Vakaki M, Wang Y, Facciabene A, Lee D, Roy P, Buchser WJ, Appleman LJ, Maranchie J, Storkus WJ, Lotze MT. Inhibiting Autophagy in Renal Cell Cancer and the Associated Tumor Endothelium. Cancer J. 2019 May/Jun;25(3):165-177. doi: 10.1097/PPO.0000000000000374. PubMed PMID: 31135523.
Guo ZS, Lu B, Guo Z, Giehl E, Feist M, Dai E, Liu W, Storkus WJ, He Y, Liu Z, Bartlett DL. Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics. J Immunother Cancer. 2019 Jan 9;7(1):6. doi: 10.1186/s40425-018-0495-7. PubMed PMID: 30626434; PMCID: PMC6325819.
Weinstein AM, Giraldo NA, Petitprez F, Julie C, Lacroix L, Peschaud F, Emile JF, Marisa L, Fridman WH, Storkus WJ, Sautès-Fridman C. Association of IL-36γ with tertiary lymphoid structures and inflammatory immune infiltrates in human colorectal cancer. Cancer Immunol Immunother. 2019 Jan;68(1):109-120. doi: 10.1007/s00262-018-2259-0. PubMed PMID: 30315348; PMCID: PMC7185158.
Choi J, Beaino W, Fecek RJ, Fabian KPL, Laymon CM, Kurland BF, Storkus WJ, Anderson CJ. Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma. J Nucl Med. 2018 Dec;59(12):1843-1849. doi: 10.2967/jnumed.118.209510. PubMed PMID: 29959213; PMCID: PMC6278902.
Fabian KL, Storkus WJ. Immunotherapeutic Targeting of Tumor-Associated Blood Vessels. Adv Exp Med Biol. 2017;1036191-211. doi: 10.1007/978-3-319-67577-0_13. PubMed PMID: 29275473.
Liu Z, Hao X, Zhang Y, Zhang J, Carey CD, Falo LD Jr, Storkus WJ, You Z. Intratumoral delivery of tumor antigen-loaded DC and tumor-primed CD4+ T cells combined with agonist α-GITR mAb promotes durable CD8+ T-cell-dependent antitumor immunity. Oncoimmunology. 2017;6(6):e1315487. doi: 10.1080/2162402X.2017.1315487. PubMed PMID: 28680744; PMCID: PMC5486177.
Weinstein AM, Chen L, Brzana EA, Patil PR, Taylor JL, Fabian KL, Wallace CT, Jones SD, Watkins SC, Lu B, Stroncek DF, Denning TL, Fu YX, Cohen PA, Storkus WJ. Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment. Oncoimmunology. 2017;6(6):e1322238. doi: 10.1080/2162402X.2017.1322238. PubMed PMID: 28680760; PMCID: PMC5486180.
Guo ZS, Liu Z, Kowalsky S, Feist M, Kalinski P, Lu B, Storkus WJ, Bartlett DL. Oncolytic Immunotherapy: Conceptual Evolution, Current Strategies, and Future Perspectives. Front Immunol. 2017;8555. doi: 10.3389/fimmu.2017.00555. PubMed PMID: 28555136; PMCID: PMC5430078.
Vujanovic L, Stahl EC, Pardee AD, Geller DA, Tsung A, Watkins SC, Gibson GA, Storkus WJ, Butterfield LH. Tumor-Derived α-Fetoprotein Directly Drives Human Natural Killer-Cell Activation and Subsequent Cell Death. Cancer Immunol Res. 2017 Jun;5(6):493-502. doi: 10.1158/2326-6066.CIR-16-0216. PubMed PMID: 28468916.
Fabian KP, Chi-Sabins N, Taylor JL, Fecek R, Weinstein A, Storkus WJ. Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice. Oncoimmunology. 2017;6(3):e1290035. doi: 10.1080/2162402X.2017.1290035. PubMed PMID: 28405524; PMCID: PMC5384378.
Tarhini AA, Tawbi H, Storkus WJ. Vaccine therapy + dasatinib for the treatment of patients with stage IIIB-IV melanoma. Melanoma Manag. 2016 Dec;3(4):251-254. doi: 10.2217/mmt-2016-0016. PubMed PMID: 30190895; PMCID: PMC6094598.
Fecek RJ, Storkus WJ. Combination strategies to enhance the potency of monocyte-derived dendritic cell-based cancer vaccines. Immunotherapy. 2016 Oct;8(10):1205-18. doi: 10.2217/imt-2016-0071. PubMed PMID: 27605069; PMCID: PMC5619021.
Weinstein AM, Storkus WJ. Biosynthesis and Functional Significance of Peripheral Node Addressin in Cancer-Associated TLO. Front Immunol. 2016;7301. doi: 10.3389/fimmu.2016.00301. PubMed PMID: 27555845; PMCID: PMC4977569.
Raïch-Regué D, Fabian KP, Watson AR, Fecek RJ, Storkus WJ, Thomson AW. Intratumoral delivery of mTORC2-deficient dendritic cells inhibits B16 melanoma growth by promoting CD8(+) effector T cell responses. Oncoimmunology. 2016 Jun;5(6):e1146841. doi: 10.1080/2162402X.2016.1146841. PubMed PMID: 27471613; PMCID: PMC4938309.
Ghosh T, Barik S, Bhuniya A, Dhar J, Dasgupta S, Ghosh S, Sarkar M, Guha I, Sarkar K, Chakrabarti P, Saha B, Storkus WJ, Baral R, Bose A. Tumor-associated mesenchymal stem cells inhibit naïve T cell expansion by blocking cysteine export from dendritic cells. Int J Cancer. 2016 Nov 1;139(9):2068-81. doi: 10.1002/ijc.30265. PubMed PMID: 27405489.
Gigante M, Pontrelli P, Herr W, Gigante M, D'Avenia M, Zaza G, Cavalcanti E, Accetturo M, Lucarelli G, Carrieri G, Battaglia M, Storkus WJ, Gesualdo L, Ranieri E. miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction. J Transl Med. 2016 Apr 11;1484. doi: 10.1186/s12967-016-0841-9. PubMed PMID: 27063186; PMCID: PMC4827202.
Wang X, Zhao X, Feng C, Weinstein A, Xia R, Wen W, Lv Q, Zuo S, Tang P, Yang X, Chen X, Wang H, Zang S, Stollings L, Denning TL, Jiang J, Fan J, Zhang G, Zhang X, Zhu Y, Storkus W, Lu B. IL-36γ Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses. Cancer Cell. 2015 Sep 14;28(3):296-306. doi: 10.1016/j.ccell.2015.07.014. PubMed PMID: 26321222; PMCID: PMC4573903.
Weinstein AM, Storkus WJ. Therapeutic Lymphoid Organogenesis in the Tumor Microenvironment. Adv Cancer Res. 2015;128197-233. doi: 10.1016/bs.acr.2015.04.003. PubMed PMID: 26216634; PMCID: PMC4853818.
Zhang Y, Chen G, Liu Z, Tian S, Zhang J, Carey CD, Murphy KM, Storkus WJ, Falo LD Jr, You Z. Genetic vaccines to potentiate the effective CD103+ dendritic cell-mediated cross-priming of antitumor immunity. J Immunol. 2015 Jun 15;194(12):5937-47. doi: 10.4049/jimmunol.1500089. PubMed PMID: 25972487; PMCID: PMC4458448.
Zhang Y, Tian S, Liu Z, Zhang J, Zhang M, Bosenberg MW, Kedl RM, Waldmann TA, Storkus WJ, Falo LD Jr, You Z. Dendritic cell-derived interleukin-15 is crucial for therapeutic cancer vaccine potency. Oncoimmunology. 2014 Nov;3(10):e959321. doi: 10.4161/21624011.2014.959321. PubMed PMID: 25941586; PMCID: PMC4292719.
Wesa AK, Mandic M, Taylor JL, Moschos S, Kirkwood JM, Kwok WW, Finke JH, Storkus WJ. Circulating Type-1 Anti-Tumor CD4(+) T Cells are Preferentially Pro-Apoptotic in Cancer Patients. Front Oncol. 2014;4266. doi: 10.3389/fonc.2014.00266. PubMed PMID: 25325015; PMCID: PMC4178427.
Vujanovic L, Shi J, Kirkwood JM, Storkus WJ, Butterfield LH. Molecular mimicry of MAGE-A6 and Mycoplasma penetrans HF-2 epitopes in the induction of antitumor CD8+ T-cell responses. Oncoimmunology. 2014;3(8):e954501. doi: 10.4161/21624011.2014.954501. PubMed PMID: 25960935; PMCID: PMC4368152.

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