Publications

Anthony Schwacha

Ngo M, Wechter N, Tsai E, Shun TY, Gough A, Schurdak ME, Schwacha A, Vogt A. A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics. SLAS Discov. 2019 Jul;24(6):669-681. doi: 10.1177/2472555219829740. PubMed PMID: 30802412; PMCID: PMC6586513.
Vijayraghavan S, Tsai FL, Schwacha A. A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/M. PLoS Genet. 2016 Aug;12(8):e1006277. doi: 10.1371/journal.pgen.1006277. PubMed PMID: 27556397; PMCID: PMC4996524.
Bochman ML, Schwacha A. DNA replication: Strand separation unravelled. Nature. 2015 Aug 13;524(7564):166-7. doi: 10.1038/nature14643. PubMed PMID: 26222029.
Tsai FL, Vijayraghavan S, Prinz J, MacAlpine HK, MacAlpine DM, Schwacha A. Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. Mol Cell Biol. 2015 Jun;35(12):2131-43. doi: 10.1128/MCB.01357-14. PubMed PMID: 25870112; PMCID: PMC4438241.
Simon NE, Schwacha A. The Mcm2-7 replicative helicase: a promising chemotherapeutic target. Biomed Res Int. 2014;2014549719. doi: 10.1155/2014/549719. PubMed PMID: 25243149; PMCID: PMC4163376.

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