Publications

Deborah Galson, PhD

Adamik J, Roodman GD, Galson DL. Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease. JBMR Plus. 2019 Mar;3(3):e10183. doi: 10.1002/jbm4.10183. PubMed PMID: 30918921; PMCID: PMC6419609.
Adamik J, Galson DL, Roodman GD. Osteoblast suppression in multiple myeloma bone disease. J Bone Oncol. 2018 Nov;1362-70. doi: 10.1016/j.jbo.2018.09.001. PubMed PMID: 30591859; PMCID: PMC6303385.
Pulugulla SH, Workman R, Rutter NW, Yang Z, Adamik J, Lupish B, Macar DA, El Abdouni S, Esposito EX, Galson DL, Camacho CJ, Madura JD, Auron PE. A combined computational and experimental approach reveals the structure of a C/EBPβ-Spi1 interaction required for IL1B gene transcription. J Biol Chem. 2018 Dec 28;293(52):19942-19956. doi: 10.1074/jbc.RA118.005627. PubMed PMID: 30355733; PMCID: PMC6311527.
Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 2018 Nov;111373-381. doi: 10.1016/j.cyto.2018.10.001. PubMed PMID: 30300855; PMCID: PMC6364691.
Petrusca DN, Toscani D, Wang FM, Park C, Crean CD, Anderson JL, Marino S, Mohammad KS, Zhou D, Silbermann R, Sun Q, Kurihara N, Galson DL, Giuliani N, Roodman GD. Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis. J Hematol Oncol. 2018 Oct 4;11(1):123. doi: 10.1186/s13045-018-0666-5. PubMed PMID: 30286780; PMCID: PMC6172782.
Adamik J, Silbermann R, Marino S, Sun Q, Anderson JL, Zhou D, Xie XQ, Roodman GD, Galson DL. XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression. Front Endocrinol (Lausanne). 2018;9344. doi: 10.3389/fendo.2018.00344. PubMed PMID: 30008697; PMCID: PMC6033965.
Lontos K, Adamik J, Tsagianni A, Galson DL, Chirgwin JM, Suvannasankha A. The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis. Front Endocrinol (Lausanne). 2018;9322. doi: 10.3389/fendo.2018.00322. PubMed PMID: 29971044; PMCID: PMC6018527.
Adamik J, Jin S, Sun Q, Zhang P, Weiss KR, Anderson JL, Silbermann R, Roodman GD, Galson DL. EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation. Mol Cancer Res. 2017 Apr;15(4):405-417. doi: 10.1158/1541-7786.MCR-16-0242-T. PubMed PMID: 28119431; PMCID: PMC5524543.
Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015 Jul 7;67531. doi: 10.1038/ncomms8531. PubMed PMID: 26151572; PMCID: PMC4498276.

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