The central mission of CEPP is to reduce cancer burden and mortality in humans. CEPP investigators conduct research in support of this mission, with two primary aims: 1) discover and characterize environmental and genetic risk factors for cancer, 2) develop and test strategies for primary and secondary cancer prevention. The research activities and scientific accomplishments of the CEPP are organized around two programmatic groups:
- Cancer Epidemiology
- Cancer Prevention
Interacting with investigators from basic and clinical sciences, the two groups maintain a translational focus by working in population settings and generating new knowledge with direct and immediate relevance to human applications.
The Cancer Prevention research group focuses on the discovery and testing of novel cancer preventive agents and approaches for primary and secondary cancer prevention. Areas of emphasis include:
1. Pre-clinical studies for discovery of new chemo- and biological agents for cancer prevention;
2. Discovery and testing novel chemo- and biological agents for primary cancer prevention in human populations; and
3. Discovery and testing biomarkers and imaging approaches for cancer screening and early detection.
The Cancer Epidemiology research identifies primary risk and preventive factors for cancer that can be translated to cancer interventions. CEPP members conduct novel epidemiologic research across many cancer types and employ state-of-the-art study designs and modern technologies to quantify biomarkers as in vivo exposure dose measures of specific environmental and physiologic agents. Areas of emphasis include:
1. The role of environmental and lifestyle exposures in the etiology of cancer; and
2. Molecular epidemiology of investigating biomarkers for environmental exposures and host response, genetic susceptibility, and gene-environmental interaction on risk of cancer.