An NCI-designated Comprehensive Cancer Center, affiliated with the University of Pittsburgh School of Medicine
Research
Medicaid is the largest insurance program in the United States and provides health care coverage for many low-income individuals. Medicaid is administered at the state level, and therefore, the structure and extent of coverage provided in each state varies across…
Immunotherapy drugs that utilize the immune system to detect and kill cancer cells have been successful against several cancers, yet they are still only effective in approximately 10 to 30 percent of patients with certain tumor types. UPMC Hillman Cancer…
A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing “fusion genes” and improves survival in mouse models of aggressive liver and prostate cancers, UPCI researchers reported in a study published this month in Nature Biotechnology. Fusion genes,…
Oncolytic viruses can selectively kill cancer cells and cancer-promoting cells, either directly by binding and infecting them, or indirectly by eliciting a targeted immune response against them. UPCI investigators have been examining the anti-cancer efficacy of an immune-stimulating vaccinia virus,…
The Metastatic Breast Cancer Network is a volunteer, patient-led advocacy organization that seeks to address the unique needs and concerns of women and men who are living with metastatic or stage IV breast cancer. One of the ways in which…
Pittsburgh scientists and doctors are embarking on the first-ever clinical trial to determine if a genetic test they pioneered could successfully spare patients with nonaggressive thyroid cancer from complete removal of their thyroid, a butterfly-shaped gland in the neck that…
While it is commonly known that vaccines can be used to prevent infectious diseases, researchers have also been exploring the use of vaccines for cancer prevention. Olivera Finn, PhD, Distinguished Professor of Immunology and Surgery, has dedicated her career to…
Skin cancer is the most common type of cancer worldwide. The most deadly form of skin cancer, melanoma, kills about 10,000 Americans per year. Routine screening enables earlier detection of skin lesions, when they are thinner and localized and can…
A team of researchers led by Patricia Opresko, PhD, Associate Professor of Environmental and Occupational Health at Pitt, and member of the UPCI Molecular and Cellular Cancer Biology Program and Carnegie Mellon University Center for Nucleic Acids Science and Technology,…
Stanley Marks, MD, a leading UPMC oncologist and advocate for cancer patients throughout the western Pennsylvania region, was honored this month by UPMC and his medical partners at Oncology Hematology Association (OHA) through the establishment of the Stanley M. Marks…
