Publications

Genotoxic Stress Responses

Maxwell JH, Mehta V, Wang H, Cunningham D, Duvvuri U, Kim S, Johnson JT, Ferris RL. Quality of life in head and neck cancer patients: impact of HPV and primary treatment modality. Laryngoscope. 2014 Jul;124(7):1592-7. doi: 10.1002/lary.24508. PubMed PMID: 24353066.
Van Houten B, Kad N. Investigation of bacterial nucleotide excision repair using single-molecule techniques. DNA Repair (Amst). 2014 Aug;2041-48. doi: 10.1016/j.dnarep.2013.10.012. PubMed PMID: 24472181; PMCID: PMC5053424.
Chen X, Meng J, Yue W, Yu J, Yang J, Yao Z, Zhang L. Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion. Carcinogenesis. 2014 Aug;35(8):1707-16. doi: 10.1093/carcin/bgu023. PubMed PMID: 24480807; PMCID: PMC4123641.
Lin J, Kaur P, Countryman P, Opresko PL, Wang H. Unraveling secrets of telomeres: one molecule at a time. DNA Repair (Amst). 2014 Aug;20142-153. doi: 10.1016/j.dnarep.2014.01.012. PubMed PMID: 24569170; PMCID: PMC4833095.
Chen D, Wei L, Yu J, Zhang L. Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis. Clin Cancer Res. 2014 Jul 1;20(13):3472-84. doi: 10.1158/1078-0432.CCR-13-2944. PubMed PMID: 24763611; PMCID: PMC4079733.
Hartman KG, Bortner JD Jr, Falk GW, Ginsberg GG, Jhala N, Yu J, Martín MG, Rustgi AK, Lynch JP. Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems. Exp Biol Med (Maywood). 2014 Sep;239(9):1108-23. doi: 10.1177/1535370214529388. PubMed PMID: 24781339; PMCID: PMC4156523.
Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN. Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase. J Immunol. 2014 Jun 15;192(12):5933-42. doi: 10.4049/jimmunol.1303470. PubMed PMID: 24799566; PMCID: PMC4078001.
Armstrong MJ, Yang H, Yip L, Ohori NP, McCoy KL, Stang MT, Hodak SP, Nikiforova MN, Carty SE, Nikiforov YE. PAX8/PPARγ rearrangement in thyroid nodules predicts follicular-pattern carcinomas, in particular the encapsulated follicular variant of papillary carcinoma. Thyroid. 2014 Sep;24(9):1369-74. doi: 10.1089/thy.2014.0067. PubMed PMID: 24798894; PMCID: PMC4148057.
Chakraborty S, Umasankar PK, Preston GM, Khandelwal P, Apodaca G, Watkins SC, Traub LM. A phosphotyrosine switch for cargo sequestration at clathrin-coated buds. J Biol Chem. 2014 Jun 20;289(25):17497-514. doi: 10.1074/jbc.M114.556589. PubMed PMID: 24798335; PMCID: PMC4067187.
Hughes CD, Simons M, Mackenzie CE, Van Houten B, Kad NM. Single molecule techniques in DNA repair: a primer. DNA Repair (Amst). 2014 Aug;202-13. doi: 10.1016/j.dnarep.2014.02.003. PubMed PMID: 24819596; PMCID: PMC5125534.
Hsiao SJ, Nikiforov YE. Molecular approaches to thyroid cancer diagnosis. Endocr Relat Cancer. 2014 Oct;21(5):T301-13. doi: 10.1530/ERC-14-0166. PubMed PMID: 24829266; PMCID: PMC4160369.
Hartman DJ, Krasinskas AM, Uttam S, Staton K, Bista R, Rizvi S, Slivka A, Brand R, Liu Y. Assessment of nuclear nanomorphology marker to improve the detection of malignancy from bile duct biopsy specimens. Am J Clin Pathol. 2014 Jun;141(6):884-91. doi: 10.1309/AJCPXQD0NSJNK0CX. PubMed PMID: 24838334; PMCID: PMC4131989.
Hwang H, Kreig A, Calvert J, Lormand J, Kwon Y, Daley JM, Sung P, Opresko PL, Myong S. Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins. Structure. 2014 Jun 10;22(6):842-53. doi: 10.1016/j.str.2014.03.013. PubMed PMID: 24836024; PMCID: PMC4067947.
Long OS, Benson JA, Kwak JH, Luke CJ, Gosai SJ, O'Reilly LP, Wang Y, Li J, Vetica AC, Miedel MT, Stolz DB, Watkins SC, Züchner S, Perlmutter DH, Silverman GA, Pak SC. A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover. Hum Mol Genet. 2014 Oct 1;23(19):5109-22. doi: 10.1093/hmg/ddu235. PubMed PMID: 24838286; PMCID: PMC4159155.
Nakatsukasa K, Kamura T, Brodsky JL. Recent technical developments in the study of ER-associated degradation. Curr Opin Cell Biol. 2014 Aug;2982-91. doi: 10.1016/j.ceb.2014.04.008. PubMed PMID: 24867671; PMCID: PMC4130770.
Yip L, Wharry LI, Armstrong MJ, Silbermann A, McCoy KL, Stang MT, Ohori NP, LeBeau SO, Coyne C, Nikiforova MN, Bauman JE, Johnson JT, Tublin ME, Hodak SP, Nikiforov YE, Carty SE. A clinical algorithm for fine-needle aspiration molecular testing effectively guides the appropriate extent of initial thyroidectomy. Ann Surg. 2014 Jul;260(1):163-8. doi: 10.1097/SLA.0000000000000215. PubMed PMID: 24901361.
Katz TA, Vasilatos SN, Harrington E, Oesterreich S, Davidson NE, Huang Y. Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells. Breast Cancer Res Treat. 2014 Jul;146(1):99-108. doi: 10.1007/s10549-014-3012-9. PubMed PMID: 24924415.
Berhane H, Shinde A, Kalash R, Xu K, Epperly MW, Goff J, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Li S, Gao X, Greenberger JS. Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039. Radiat Res. 2014 Jul;182(1):35-49. doi: 10.1667/RR13633.1. PubMed PMID: 24932534; PMCID: PMC4101533.
Tang D, Kang R, Van Houten B, Zeh HJ, Billiar TR, Lotze MT. High mobility group box 1 (HMGB1) phenotypic role revealed with stress. Mol Med. 2014 Aug 19;20359-62. doi: 10.2119/molmed.2014.00063. PubMed PMID: 24937773; PMCID: PMC4153844.
Muller L, Hong CS, Stolz DB, Watkins SC, Whiteside TL. Isolation of biologically-active exosomes from human plasma. J Immunol Methods. 2014 Sep;41155-65. doi: 10.1016/j.jim.2014.06.007. PubMed PMID: 24952243; PMCID: PMC4260336.
Qian W, Wang J, Roginskaya V, McDermott LA, Edwards RP, Stolz DB, Llambi F, Green DR, Van Houten B. Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells. Oncotarget. 2014 Jun 30;5(12):4180-94. doi: 10.18632/oncotarget.1944. PubMed PMID: 24952704; PMCID: PMC4147315.
Xu Y, Lin Z, Zhao N, Zhou L, Liu F, Cichacz Z, Zhang L, Zhan Q, Zhao X. Receptor interactive protein kinase 3 promotes Cisplatin-triggered necrosis in apoptosis-resistant esophageal squamous cell carcinoma cells. PLoS One. 2014;9(6):e100127. doi: 10.1371/journal.pone.0100127. PubMed PMID: 24959694; PMCID: PMC4069059.
Shinde A, Epperly MW, Cao S, Franicola D, Shields D, Wang H, Wipf P, Sprachman MM, Greenberger JS. Effects of the bifunctional sulfoxide MMS350, a radiation mitigator, on hematopoiesis in long-term bone marrow cultures and on radioresistance of marrow stromal cell lines. In Vivo. 2014 Jul-Aug;28(4):457-65. PubMed PMID: 24982210; PMCID: PMC6591577.
Epperly MW, Goff JP, Franicola D, Wang H, Wipf P, Li S, Greenberger JS. Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors. In Vivo. 2014 Jul-Aug;28(4):435-40. PubMed PMID: 24982207; PMCID: PMC6436097.
Katz TA, Huang Y, Davidson NE, Jankowitz RC. Epigenetic reprogramming in breast cancer: from new targets to new therapies. Ann Med. 2014 Sep;46(6):397-408. doi: 10.3109/07853890.2014.923740. PubMed PMID: 25058177.
Murphy CT, Gupta A, Armitage BA, Opresko PL. Hybridization of G-quadruplex-forming peptide nucleic acids to guanine-rich DNA templates inhibits DNA polymerase η extension. Biochemistry. 2014 Aug 19;53(32):5315-22. doi: 10.1021/bi5006859. PubMed PMID: 25068499.
Pham HH, Murphy CT, Sureshkumar G, Ly DH, Opresko PL, Armitage BA. Cooperative hybridization of γPNA miniprobes to a repeating sequence motif and application to telomere analysis. Org Biomol Chem. 2014 Oct 7;12(37):7345-7354. doi: 10.1039/c4ob00953c. PubMed PMID: 25115693; PMCID: PMC4162129.
Nakajima EC, Laymon C, Oborski M, Hou W, Wang L, Grandis JR, Ferris RL, Mountz JM, Van Houten B. Quantifying metabolic heterogeneity in head and neck tumors in real time: 2-DG uptake is highest in hypoxic tumor regions. PLoS One. 2014;9(8):e102452. doi: 10.1371/journal.pone.0102452. PubMed PMID: 25127378; PMCID: PMC4134191.
Radkay LA, Chiosea SI, Seethala RR, Hodak SP, LeBeau SO, Yip L, McCoy KL, Carty SE, Schoedel KE, Nikiforova MN, Nikiforov YE, Ohori NP. Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics. Cancer Cytopathol. 2014 Dec;122(12):873-82. doi: 10.1002/cncy.21474. PubMed PMID: 25132659.
Böhm S, Bernstein KA. The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair. DNA Repair (Amst). 2014 Oct;22123-32. doi: 10.1016/j.dnarep.2014.07.007. PubMed PMID: 25150915; PMCID: PMC4175148.
de Moura MB, Uppala R, Zhang Y, Van Houten B, Goetzman ES. Overexpression of mitochondrial sirtuins alters glycolysis and mitochondrial function in HEK293 cells. PLoS One. 2014;9(8):e106028. doi: 10.1371/journal.pone.0106028. PubMed PMID: 25165814; PMCID: PMC4148395.
O'Sullivan RJ, Almouzni G. Assembly of telomeric chromatin to create ALTernative endings. Trends Cell Biol. 2014 Nov;24(11):675-85. doi: 10.1016/j.tcb.2014.07.007. PubMed PMID: 25172551.
Shinde A, Epperly MW, Cao S, Holt D, Goff J, Shields D, Franicola D, Wipf P, Wang H, Greenberger JS. Improved hematopoiesis in GS-nitroxide (JP4-039)-treated mouse long-term bone marrow cultures and radioresistance of derived bone marrow stromal cell lines. In Vivo. 2014 Sep-Oct;28(5):699-708. PubMed PMID: 25189880; PMCID: PMC6477534.
Nikiforov YE, Carty SE, Chiosea SI, Coyne C, Duvvuri U, Ferris RL, Gooding WE, Hodak SP, LeBeau SO, Ohori NP, Seethala RR, Tublin ME, Yip L, Nikiforova MN. Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay. Cancer. 2014 Dec 1;120(23):3627-34. doi: 10.1002/cncr.29038. PubMed PMID: 25209362.
Fouquerel E, Goellner EM, Yu Z, Gagné JP, Barbi de Moura M, Feinstein T, Wheeler D, Redpath P, Li J, Romero G, Migaud M, Van Houten B, Poirier GG, Sobol RW. ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. Cell Rep. 2014 Sep 25;8(6):1819-1831. doi: 10.1016/j.celrep.2014.08.036. PubMed PMID: 25220464; PMCID: PMC4177344.
Chen D, Ming L, Zou F, Peng Y, Van Houten B, Yu J, Zhang L. TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity. Oncotarget. 2014 Sep 30;5(18):8107-22. doi: 10.18632/oncotarget.2440. PubMed PMID: 25237903; PMCID: PMC4226670.
Surlow BA, Cooley BM, Needham PG, Brodsky JL, Patton-Vogt J. Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation. J Biol Chem. 2014 Nov 7;289(45):31591-604. doi: 10.1074/jbc.M114.581157. PubMed PMID: 25258318; PMCID: PMC4223355.
Hwang H, Opresko P, Myong S. Single-molecule real-time detection of telomerase extension activity. Sci Rep. 2014 Sep 29;46391. doi: 10.1038/srep06391. PubMed PMID: 25263700; PMCID: PMC4178293.
Yanamala N, Kapralov AA, Djukic M, Peterson J, Mao G, Klein-Seetharaman J, Stoyanovsky DA, Stursa J, Neuzil J, Kagan VE. Structural re-arrangement and peroxidase activation of cytochrome c by anionic analogues of vitamin E, tocopherol succinate and tocopherol phosphate. J Biol Chem. 2014 Nov 21;289(47):32488-98. doi: 10.1074/jbc.M114.601377. PubMed PMID: 25278024; PMCID: PMC4239604.
Shao H, Li S, Watkins SC, Wells A. α-Actinin-4 is required for amoeboid-type invasiveness of melanoma cells. J Biol Chem. 2014 Nov 21;289(47):32717-28. doi: 10.1074/jbc.M114.579185. PubMed PMID: 25296750; PMCID: PMC4239623.
Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins SC, Sarkar SN, Okada H. STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment. Cancer Immunol Res. 2014 Dec;2(12):1199-208. doi: 10.1158/2326-6066.CIR-14-0099. PubMed PMID: 25300859; PMCID: PMC4258479.
Pope-Varsalona H, Liu FJ, Guzik L, Opresko PL. Polymerase η suppresses telomere defects induced by DNA damaging agents. Nucleic Acids Res. 2014 Dec 1;42(21):13096-109. doi: 10.1093/nar/gku1030. PubMed PMID: 25355508; PMCID: PMC4245935.
Leibowitz B, Qiu W, Buchanan ME, Zou F, Vernon P, Moyer MP, Yin XM, Schoen RE, Yu J, Zhang L. BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16520-5. doi: 10.1073/pnas.1415178111. PubMed PMID: 25368155; PMCID: PMC4246283.
Rhieu BH, Shinde A, Epperly MW, Dixon T, Wang H, Chaillet R, Greenberger JS. Organ-specific responses of total body irradiated doxycycline-inducible manganese superoxide dismutase Tet/Tet mice. In Vivo. 2014 Nov-Dec;28(6):1033-43. PubMed PMID: 25398796; PMCID: PMC6436100.
Buck TM, Brodsky JL. Escaping the endoplasmic reticulum: why does a molecular chaperone leave home for greener pastures? EMBO J. 2015 Jan 2;34(1):1-3. doi: 10.15252/embj.201490462. PubMed PMID: 25425576; PMCID: PMC4291476.
Brodsky JL, Clark PL. Protein folding in the cell, from atom to organism. FASEB J. 2014 Dec;28(12):5034-8. doi: 10.1096/fj.14-1202ufm. PubMed PMID: 25451678; PMCID: PMC6190966.
Ireland AW, Gobillot TA, Gupta T, Seguin SP, Liang M, Resnick L, Goldberg MT, Manos-Turvey A, Pipas JM, Wipf P, Brodsky JL. Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target. Bioorg Med Chem. 2014 Nov 15;22(22):6490-6502. doi: 10.1016/j.bmc.2014.09.019. PubMed PMID: 25440730; PMCID: PMC4293281.
Howe MK, Bodoor K, Carlson DA, Hughes PF, Alwarawrah Y, Loiselle DR, Jaeger AM, Darr DB, Jordan JL, Hunter LM, Molzberger ET, Gobillot TA, Thiele DJ, Brodsky JL, Spector NL, Haystead TA. Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70. Chem Biol. 2014 Dec 18;21(12):1648-59. doi: 10.1016/j.chembiol.2014.10.016. PubMed PMID: 25500222; PMCID: PMC4272656.
Stoyanovsky DA, Jiang J, Murphy MP, Epperly M, Zhang X, Li S, Greenberger J, Kagan V, Bayır H. Design and Synthesis of a Mitochondria-Targeted Mimic of Glutathione Peroxidase, MitoEbselen-2, as a Radiation Mitigator. ACS Med Chem Lett. 2014 Dec 11;5(12):1304-1307. doi: 10.1021/ml5003635. PubMed PMID: 25530831; PMCID: PMC4266336.
Dralle H, Machens A, Basa J, Fatourechi V, Franceschi S, Hay ID, Nikiforov YE, Pacini F, Pasieka JL, Sherman SI. Follicular cell-derived thyroid cancer. Nat Rev Dis Primers. 2015 Dec 10;115077. doi: 10.1038/nrdp.2015.77. PubMed PMID: 27188261.
Teng PN, Bateman NW, Darcy KM, Hamilton CA, Maxwell GL, Bakkenist CJ, Conrads TP. Pharmacologic inhibition of ATR and ATM offers clinically important distinctions to enhancing platinum or radiation response in ovarian, endometrial, and cervical cancer cells. Gynecol Oncol. 2015 Mar;136(3):554-61. doi: 10.1016/j.ygyno.2014.12.035. PubMed PMID: 25560806; PMCID: PMC4382918.
Chen X, Velmurugu Y, Zheng G, Park B, Shim Y, Kim Y, Liu L, Van Houten B, He C, Ansari A, Min JH. Kinetic gating mechanism of DNA damage recognition by Rad4/XPC. Nat Commun. 2015 Jan 6;65849. doi: 10.1038/ncomms6849. PubMed PMID: 25562780; PMCID: PMC4354021.
Kagan VE, Tyurina YY, Tyurin VA, Mohammadyani D, Angeli JP, Baranov SV, Klein-Seetharaman J, Friedlander RM, Mallampalli RK, Conrad M, Bayir H. Cardiolipin signaling mechanisms: collapse of asymmetry and oxidation. Antioxid Redox Signal. 2015 Jun 20;22(18):1667-80. doi: 10.1089/ars.2014.6219. PubMed PMID: 25566681; PMCID: PMC4486147.
Qian W, Salamoun J, Wang J, Roginskaya V, Van Houten B, Wipf P. The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak. Bioorg Med Chem Lett. 2015 Feb 15;25(4):856-63. doi: 10.1016/j.bmcl.2014.12.072. PubMed PMID: 25582599; PMCID: PMC4318771.
Böhm S, Mihalevic MJ, Casal MA, Bernstein KA. Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells. DNA Repair (Amst). 2015 Feb;261-14. doi: 10.1016/j.dnarep.2014.12.004. PubMed PMID: 25588990; PMCID: PMC4308569.
Buryk MA, Simons JP, Picarsic J, Monaco SE, Ozolek JA, Joyce J, Gurtunca N, Nikiforov YE, Feldman Witchel S. Can malignant thyroid nodules be distinguished from benign thyroid nodules in children and adolescents by clinical characteristics? A review of 89 pediatric patients with thyroid nodules. Thyroid. 2015 Apr;25(4):392-400. doi: 10.1089/thy.2014.0312. PubMed PMID: 25627462.
Crum TS, Gleixner AM, Posimo JM, Mason DM, Broeren MT, Heinemann SD, Wipf P, Brodsky JL, Leak RK. Heat shock protein responses to aging and proteotoxicity in the olfactory bulb. J Neurochem. 2015 Jun;133(6):780-794. doi: 10.1111/jnc.13041. PubMed PMID: 25640060; PMCID: PMC4464935.
Godin SK, Meslin C, Kabbinavar F, Bratton-Palmer DS, Hornack C, Mihalevic MJ, Yoshida K, Sullivan M, Clark NL, Bernstein KA. Evolutionary and functional analysis of the invariant SWIM domain in the conserved Shu2/SWS1 protein family from Saccharomyces cerevisiae to Homo sapiens. Genetics. 2015 Apr;199(4):1023-33. doi: 10.1534/genetics.114.173518. PubMed PMID: 25659377; PMCID: PMC4391554.
Li H, Wu HC, Liu Z, Zacchi LF, Brodsky JL, Zolkiewski M. Intracellular complexes of the early-onset torsion dystonia-associated AAA+ ATPase TorsinA. Springerplus. 2014;3743. doi: 10.1186/2193-1801-3-743. PubMed PMID: 25674472; PMCID: PMC4320221.
Argani P, Lewin JR, Edmonds P, Netto GJ, Prieto-Granada C, Zhang L, Jungbluth AA, Antonescu CR. Primary renal sclerosing epithelioid fibrosarcoma: report of 2 cases with EWSR1-CREB3L1 gene fusion. Am J Surg Pathol. 2015 Mar;39(3):365-73. doi: 10.1097/PAS.0000000000000338. PubMed PMID: 25353281; PMCID: PMC4326586.
Shvedova AA, Kisin ER, Yanamala N, Tkach AV, Gutkin DW, Star A, Shurin GV, Kagan VE, Shurin MR. MDSC and TGFβ Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes. Cancer Res. 2015 Apr 15;75(8):1615-23. doi: 10.1158/0008-5472.CAN-14-2376. PubMed PMID: 25744719; PMCID: PMC4401633.
Arndt KM, Reines D. Termination of Transcription of Short Noncoding RNAs by RNA Polymerase II. Annu Rev Biochem. 2015;84381-404. doi: 10.1146/annurev-biochem-060614-034457. PubMed PMID: 25747400; PMCID: PMC5104496.
Buryk MA, Picarsic JL, Creary SE, Shaw PH, Simons JP, Deutsch M, Monaco SE, Nikiforov YE, Witchel SF. Identification of Unique, Heterozygous Germline Mutation, STK11 (p.F354L), in a Child with an Encapsulated Follicular Variant of Papillary Thyroid Carcinoma within Six Months of Completing Treatment for Neuroblastoma. Pediatr Dev Pathol. 2015 Jul-Aug;18(4):318-23. doi: 10.2350/15-01-1597-CR.1. PubMed PMID: 25751324.
An P, Brodsky JL, Pipas JM. The conserved core enzymatic activities and the distinct dynamics of polyomavirus large T antigens. Arch Biochem Biophys. 2015 May 1;57323-31. doi: 10.1016/j.abb.2015.02.033. PubMed PMID: 25752954; PMCID: PMC4865250.
Buck TM, Jordan R, Lyons-Weiler J, Adelman JL, Needham PG, Kleyman TR, Brodsky JL. Expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae. Physiol Genomics. 2015 Jun;47(6):198-214. doi: 10.1152/physiolgenomics.00101.2014. PubMed PMID: 25759377; PMCID: PMC4451388.
Posimo JM, Weilnau JN, Gleixner AM, Broeren MT, Weiland NL, Brodsky JL, Wipf P, Leak RK. Heat shock protein defenses in the neocortex and allocortex of the telencephalon. Neurobiol Aging. 2015 May;36(5):1924-37. doi: 10.1016/j.neurobiolaging.2015.02.011. PubMed PMID: 25771395; PMCID: PMC4417007.
Zeng Y, Liu Y, Shang J, Ma J, Wang R, Deng L, Guo Y, Zhong F, Bai M, Zhang S, Wu D. Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound. PLoS One. 2015;10(3):e0121293. doi: 10.1371/journal.pone.0121293. PubMed PMID: 25786221; PMCID: PMC4365010.
Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, Schmitt-Graeff A, Nakae S, Follo M, Wertheimer T, Schwab L, Devlin J, Watkins SC, Duyster J, Ferrara JL, Turnquist HR, Zeiser R, Blazar BR. The IL-33/ST2 axis augments effector T-cell responses during acute GVHD. Blood. 2015 May 14;125(20):3183-92. doi: 10.1182/blood-2014-10-606830. PubMed PMID: 25814531; PMCID: PMC4432012.
Knickelbein K, Zhang L. Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer. Genes Dis. 2015 Mar;2(1):4-12. doi: 10.1016/j.gendis.2014.10.002. PubMed PMID: 25815366; PMCID: PMC4372129.
Li F, Chen G, Sheng C, Gusdon AM, Huang Y, Lv Z, Xu H, Xing M, Qu S. BRAFV600E mutation in papillary thyroid microcarcinoma: a meta-analysis. Endocr Relat Cancer. 2015 Apr;22(2):159-68. doi: 10.1530/ERC-14-0531. PubMed PMID: 25593071; PMCID: PMC4629836.
Jackson TC, Bayir H, Ikonomovic MD, Janesko-Feldman K, Mi Z, Gao T, Jackson EK, Kochanek PM. Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies. Sci Rep. 2015 Apr 1;59377. doi: 10.1038/srep09377. PubMed PMID: 25827478; PMCID: PMC4649889.
Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JCY, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Sci Rep. 2015 Apr 10;58566. doi: 10.1038/srep08566. PubMed PMID: 25858503; PMCID: PMC4392360.
Seo W, Kapralov AA, Shurin GV, Shurin MR, Kagan VE, Star A. Payload drug vs. nanocarrier biodegradation by myeloperoxidase- and peroxynitrite-mediated oxidations: pharmacokinetic implications. Nanoscale. 2015 May 21;7(19):8689-94. doi: 10.1039/c5nr00251f. PubMed PMID: 25902750; PMCID: PMC4582775.
Chen X, Song X, Yue W, Chen D, Yu J, Yao Z, Zhang L. Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer. Oncotarget. 2015 Jun 20;6(17):15022-34. doi: 10.18632/oncotarget.3609. PubMed PMID: 25909283; PMCID: PMC4558133.
Needham PG, Patel HJ, Chiosis G, Thibodeau PH, Brodsky JL. Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions. J Mol Biol. 2015 Sep 11;427(18):2948-65. doi: 10.1016/j.jmb.2015.04.010. PubMed PMID: 25913688; PMCID: PMC4569534.
Maxwell JH, Rath TJ, Byrd JK, Albergotti WG, Wang H, Duvvuri U, Kim S, Johnson JT, Branstetter BF 4th, Ferris RL. Accuracy of computed tomography to predict extracapsular spread in p16-positive squamous cell carcinoma. Laryngoscope. 2015 Jul;125(7):1613-8. doi: 10.1002/lary.25140. PubMed PMID: 25946149.
Gomez-Casal R, Bhattacharya C, Epperly MW, Basse PH, Wang H, Wang X, Proia DA, Greenberger JS, Socinski MA, Levina V. The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells. Cancers (Basel). 2015 May 22;7(2):876-907. doi: 10.3390/cancers7020814. PubMed PMID: 26010604; PMCID: PMC4491689.
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. PubMed PMID: 25939062; PMCID: PMC4862411.
Wang T, Guan W, Lin J, Boutaoui N, Canino G, Luo J, Celedón JC, Chen W. A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data. Epigenetics. 2015;10(7):662-9. doi: 10.1080/15592294.2015.1057384. PubMed PMID: 26036609; PMCID: PMC4623491.
Del Portillo A, Lagana SM, Yao Y, Uehara T, Jhala N, Ganguly T, Nagy P, Gutierrez J, Luna A, Abrams J, Liu Y, Brand R, Sepulveda JL, Falk GW, Sepulveda AR. Evaluation of Mutational Testing of Preneoplastic Barrett's Mucosa by Next-Generation Sequencing of Formalin-Fixed, Paraffin-Embedded Endoscopic Samples for Detection of Concurrent Dysplasia and Adenocarcinoma in Barrett's Esophagus. J Mol Diagn. 2015 Jul;17(4):412-9. doi: 10.1016/j.jmoldx.2015.02.006. PubMed PMID: 26068095; PMCID: PMC4484205.
Bakan A, Kapralov AA, Bayir H, Hu F, Kagan VE, Bahar I. Inhibition of Peroxidase Activity of Cytochrome c: De Novo Compound Discovery and Validation. Mol Pharmacol. 2015 Sep;88(3):421-7. doi: 10.1124/mol.115.097816. PubMed PMID: 26078313; PMCID: PMC4551054.
Sun L, Tan R, Xu J, LaFace J, Gao Y, Xiao Y, Attar M, Neumann C, Li GM, Su B, Liu Y, Nakajima S, Levine AS, Lan L. Targeted DNA damage at individual telomeres disrupts their integrity and triggers cell death. Nucleic Acids Res. 2015 Jul 27;43(13):6334-47. doi: 10.1093/nar/gkv598. PubMed PMID: 26082495; PMCID: PMC4513870.
Bakkenist CJ, Czambel RK, Hershberger PA, Tawbi H, Beumer JH, Schmitz JC. A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells. Oncoscience. 2015;2(5):542-54. doi: 10.18632/oncoscience.162. PubMed PMID: 26097887; PMCID: PMC4468340.
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3495-504. doi: 10.1073/pnas.1507105112. PubMed PMID: 26100862; PMCID: PMC4500203.
Marcoline FV, Bethel N, Guerriero CJ, Brodsky JL, Grabe M. Membrane Protein Properties Revealed through Data-Rich Electrostatics Calculations. Structure. 2015 Aug 4;23(8):1526-1537. doi: 10.1016/j.str.2015.05.014. PubMed PMID: 26118532; PMCID: PMC4527966.
Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015 Jul 7;67531. doi: 10.1038/ncomms8531. PubMed PMID: 26151572; PMCID: PMC4498276.
Ma J, Lim C, Sacher JR, Van Houten B, Qian W, Wipf P. Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4828-4833. doi: 10.1016/j.bmcl.2015.06.073. PubMed PMID: 26159482; PMCID: PMC4607627.
Pardee AD, Yano H, Weinstein AM, Ponce AA, Ethridge AD, Normolle DP, Vujanovic L, Mizejewski GJ, Watkins SC, Butterfield LH. Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma. J Immunother Cancer. 2015;332. doi: 10.1186/s40425-015-0077-x. PubMed PMID: 26199728; PMCID: PMC4509479.
Gaines WA, Godin SK, Kabbinavar FF, Rao T, VanDemark AP, Sung P, Bernstein KA. Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. Nat Commun. 2015 Jul 28;67834. doi: 10.1038/ncomms8834. PubMed PMID: 26215801; PMCID: PMC4525180.
Wipf P, Eyer BR, Yamaguchi Y, Zhang F, Neal MD, Sodhi CP, Good M, Branca M, Prindle T Jr, Lu P, Brodsky JL, Hackam DJ. Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4). Tetrahedron Lett. 2015 Jun 3;56(23):3097-3100. doi: 10.1016/j.tetlet.2014.11.048. PubMed PMID: 26236050; PMCID: PMC4518473.
Cucinotta CE, Young AN, Klucevsek KM, Arndt KM. The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae. PLoS Genet. 2015 Aug;11(8):e1005420. doi: 10.1371/journal.pgen.1005420. PubMed PMID: 26241481; PMCID: PMC4524731.
Schoedel KE, Wolfe J, Hodak SP, Lebeau SO, Yip L, Carty SE, Nikiforova MN, Nikiforov YE, Ohori NP. Significance of what is not sampled: Characteristics of thyroid nonmicrocarcinomas (>1.0 cm) that were not targeted. Cancer Cytopathol. 2015 Nov;123(11):678-83. doi: 10.1002/cncy.21603. PubMed PMID: 26242638.
Fortian A, Dionne LK, Hong SH, Kim W, Gygi SP, Watkins SC, Sorkin A. Endocytosis of Ubiquitylation-Deficient EGFR Mutants via Clathrin-Coated Pits is Mediated by Ubiquitylation. Traffic. 2015 Nov;16(11):1137-54. doi: 10.1111/tra.12314. PubMed PMID: 26251007; PMCID: PMC4607634.
Yip L, Nikiforova MN, Yoo JY, McCoy KL, Stang MT, Armstrong MJ, Nicholson KJ, Ohori NP, Coyne C, Hodak SP, Ferris RL, LeBeau SO, Nikiforov YE, Carty SE. Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients. Ann Surg. 2015 Sep;262(3):519-25; discussion 524-5. doi: 10.1097/SLA.0000000000001420. PubMed PMID: 26258321; PMCID: PMC5264519.
Tong GX, Mody K, Wang Z, Hamele-Bena D, Nikiforova MN, Nikiforov YE. Mutations of TSHR and TP53 Genes in an Aggressive Clear Cell Follicular Carcinoma of the Thyroid. Endocr Pathol. 2015 Dec;26(4):315-9. doi: 10.1007/s12022-015-9388-1. PubMed PMID: 26260781.
Wallace CT, St Croix CM, Watkins SC. Data management and archiving in a large microscopy-and-imaging, multi-user facility: Problems and solutions. Mol Reprod Dev. 2015 Sep;82(9):630-4. doi: 10.1002/mrd.22538. PubMed PMID: 26284826; PMCID: PMC4878693.
Planas-Iglesias J, Dwarakanath H, Mohammadyani D, Yanamala N, Kagan VE, Klein-Seetharaman J. Cardiolipin Interactions with Proteins. Biophys J. 2015 Sep 15;109(6):1282-94. doi: 10.1016/j.bpj.2015.07.034. PubMed PMID: 26300339; PMCID: PMC4576322.
Rolyan H, Tyurina YY, Hernandez M, Amoscato AA, Sparvero LJ, Nmezi BC, Lu Y, Estécio MR, Lin K, Chen J, He RR, Gong P, Rigatti LH, Dupree J, Bayır H, Kagan VE, Casaccia P, Padiath QS. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci. 2015 Aug 26;35(34):12002-17. doi: 10.1523/JNEUROSCI.1668-15.2015. PubMed PMID: 26311780; PMCID: PMC4549407.
Lu S, Lu KN, Cheng SY, Hu B, Ma X, Nystrom N, Lu X. Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets. PLoS Comput Biol. 2015 Aug;11(8):e1004257. doi: 10.1371/journal.pcbi.1004257. PubMed PMID: 26317392; PMCID: PMC4552843.
Glassford WJ, Johnson WC, Dall NR, Smith SJ, Liu Y, Boll W, Noll M, Rebeiz M. Co-option of an Ancestral Hox-Regulated Network Underlies a Recently Evolved Morphological Novelty. Dev Cell. 2015 Sep 14;34(5):520-31. doi: 10.1016/j.devcel.2015.08.005. PubMed PMID: 26343453; PMCID: PMC4573913.
Parikh D, Fouquerel E, Murphy CT, Wang H, Opresko PL. Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts. Nat Commun. 2015 Sep 9;68214. doi: 10.1038/ncomms9214. PubMed PMID: 26351258; PMCID: PMC4566151.
Nikiforov YE, Carty SE, Chiosea SI, Coyne C, Duvvuri U, Ferris RL, Gooding WE, LeBeau SO, Ohori NP, Seethala RR, Tublin ME, Yip L, Nikiforova MN. Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Cytology. Thyroid. 2015 Nov;25(11):1217-23. doi: 10.1089/thy.2015.0305. PubMed PMID: 26356635; PMCID: PMC4652198.
Dickson R, Kim JO, Huq MS, Bednarz G, Suyama J, Yealy DM, Wang H, Greenberger JS. A Mobile Alert System for Preparing the Delivery of Radiation Mitigators. In Vivo. 2015 Sep-Oct;29(5):505-13. PubMed PMID: 26359406.
Shrestha RT, Karunamurthy A, Amin K, Nikiforov YE, Caramori ML. Multiple Mutations Detected Preoperatively May Predict Aggressive Behavior of Papillary Thyroid Cancer and Guide Management--A Case Report. Thyroid. 2015 Dec;25(12):1375-8. doi: 10.1089/thy.2015.0278. PubMed PMID: 26355276.
Picarsic JL, Buryk MA, Ozolek J, Ranganathan S, Monaco SE, Simons JP, Witchel SF, Gurtunca N, Joyce J, Zhong S, Nikiforova MN, Nikiforov YE. Molecular Characterization of Sporadic Pediatric Thyroid Carcinoma with the DNA/RNA ThyroSeq v2 Next-Generation Sequencing Assay. Pediatr Dev Pathol. 2016 Mar-Apr;19(2):115-22. doi: 10.2350/15-07-1667-OA.1. PubMed PMID: 26367451; PMCID: PMC5894824.
Uttam S, Pham HV, LaFace J, Leibowitz B, Yu J, Brand RE, Hartman DJ, Liu Y. Early Prediction of Cancer Progression by Depth-Resolved Nanoscale Mapping of Nuclear Architecture from Unstained Tissue Specimens. Cancer Res. 2015 Nov 15;75(22):4718-27. doi: 10.1158/0008-5472.CAN-15-1274. PubMed PMID: 26383164; PMCID: PMC4651746.
Bakkenist CJ, Kastan MB. Chromatin perturbations during the DNA damage response in higher eukaryotes. DNA Repair (Amst). 2015 Dec;368-12. doi: 10.1016/j.dnarep.2015.09.002. PubMed PMID: 26391293; PMCID: PMC4727245.
Balasubramanian K, Maeda A, Lee JS, Mohammadyani D, Dar HH, Jiang JF, St Croix CM, Watkins S, Tyurin VA, Tyurina YY, Klöditz K, Polimova A, Kapralova VI, Xiong Z, Ray P, Klein-Seetharaman J, Mallampalli RK, Bayir H, Fadeel B, Kagan VE. Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity. Sci Signal. 2015 Sep 22;8(395):ra95. doi: 10.1126/scisignal.aaa6179. PubMed PMID: 26396268; PMCID: PMC4760701.
Ma H, Xu J, Jin J, Gao Y, Lan L, Liu Y. Fast and Precise 3D Fluorophore Localization based on Gradient Fitting. Sci Rep. 2015 Sep 22;514335. doi: 10.1038/srep14335. PubMed PMID: 26390959; PMCID: PMC4585720.
Misale S, Bozic I, Tong J, Peraza-Penton A, Lallo A, Baldi F, Lin KH, Truini M, Trusolino L, Bertotti A, Di Nicolantonio F, Nowak MA, Zhang L, Wood KC, Bardelli A. Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers. Nat Commun. 2015 Sep 22;68305. doi: 10.1038/ncomms9305. PubMed PMID: 26392303; PMCID: PMC4595628.
Wang X, Fan F, Wang J, Wang H, Tao S, Yang A, Liu Y, Beng Chew H, Mao SX, Zhu T, Xia S. High damage tolerance of electrochemically lithiated silicon. Nat Commun. 2015 Sep 24;68417. doi: 10.1038/ncomms9417. PubMed PMID: 26400671; PMCID: PMC4598720.
Afkhami M, Karunamurthy A, Chiosea S, Nikiforova MN, Seethala R, Nikiforov YE, Coyne C. Histopathologic and Clinical Characterization of Thyroid Tumors Carrying the BRAF(K601E) Mutation. Thyroid. 2016 Feb;26(2):242-7. doi: 10.1089/thy.2015.0227. PubMed PMID: 26422023.
Khoo NKH, Cantu-Medellin N, St Croix C, Kelley EE. In Vivo Immuno-Spin Trapping: Imaging the Footprints of Oxidative Stress. Curr Protoc Cytom. 2015 Oct 1;7412.42.1-12.42.11. doi: 10.1002/0471142956.cy1242s74. PubMed PMID: 26423693; PMCID: PMC4889111.
Beumer JH, Fu KY, Anyang BN, Siegfried JM, Bakkenist CJ. Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma. BMC Cancer. 2015 Oct 5;15649. doi: 10.1186/s12885-015-1649-3. PubMed PMID: 26438152; PMCID: PMC4595318.
Phinney DG, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix CM, Stolz DB, Watkins SC, Di YP, Leikauf GD, Kolls J, Riches DW, Deiuliis G, Kaminski N, Boregowda SV, McKenna DH, Ortiz LA. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun. 2015 Oct 7;68472. doi: 10.1038/ncomms9472. PubMed PMID: 26442449; PMCID: PMC4598952.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PubMed PMID: 26462967; PMCID: PMC4739132.
Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, Menon R, Krämer A, Roncaioli JL, Sand F, Heuckmann JM, Ikram F, Schmidt R, Ackermann S, Engesser A, Kahlert Y, Vogel W, Altmüller J, Nürnberg P, Thierry-Mieg J, Thierry-Mieg D, Mariappan A, Heynck S, Mariotti E, Henrich KO, Gloeckner C, Bosco G, Leuschner I, Schweiger MR, Savelyeva L, Watkins SC, Shao C, Bell E, Höfer T, Achter V, Lang U, Theissen J, Volland R, Saadati M, Eggert A, de Wilde B, Berthold F, Peng Z, Zhao C, Shi L, Ortmann M, Büttner R, Perner S, Hero B, Schramm A, Schulte JH, Herrmann C, O'Sullivan RJ, Westermann F, Thomas RK, Fischer M. Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature. 2015 Oct 29;526(7575):700-4. doi: 10.1038/nature14980. PubMed PMID: 26466568; PMCID: PMC4881306.
Prosser DC, Pannunzio AE, Brodsky JL, Thorner J, Wendland B, O'Donnell AF. α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. J Cell Sci. 2015 Nov 15;128(22):4220-34. doi: 10.1242/jcs.175372. PubMed PMID: 26459639; PMCID: PMC4712785.
Zhang X, Peng Y, Jin Z, Huang W, Cheng Y, Liu Y, Feng X, Yang M, Huang Y, Zhao Z, Wang L, Wei Y, Fan X, Zheng D, Meltzer SJ. Integrated miRNA profiling and bioinformatics analyses reveal potential causative miRNAs in gastric adenocarcinoma. Oncotarget. 2015 Oct 20;6(32):32878-89. doi: 10.18632/oncotarget.5419. PubMed PMID: 26460735; PMCID: PMC4741736.
Vendetti FP, Lau A, Schamus S, Conrads TP, O'Connor MJ, Bakkenist CJ. The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo. Oncotarget. 2015 Dec 29;6(42):44289-305. doi: 10.18632/oncotarget.6247. PubMed PMID: 26517239; PMCID: PMC4792557.
Gomez-Casal R, Epperly MW, Wang H, Proia DA, Greenberger JS, Levina V. Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition. Oncotarget. 2015 Dec 29;6(42):44306-22. doi: 10.18632/oncotarget.6248. PubMed PMID: 26517240; PMCID: PMC4792558.
Bakkenist CJ, Beumer JH, Schmitz JC. ATM serine-1981 phosphorylation is a plausible biomarker. Cell Cycle. 2015;14(20):3207-8. doi: 10.1080/15384101.2015.1084205. PubMed PMID: 26517194; PMCID: PMC4825586.
Mandal A, Hoop CL, DeLucia M, Kodali R, Kagan VE, Ahn J, van der Wel PC. Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c. Biophys J. 2015 Nov 3;109(9):1873-84. doi: 10.1016/j.bpj.2015.09.016. PubMed PMID: 26536264; PMCID: PMC4643272.
Liu S, Tsai WH, Ding Y, Chen R, Fang Z, Huo Z, Kim S, Ma T, Chang TY, Priedigkeit NM, Lee AV, Luo J, Wang HW, Chung IF, Tseng GC. Comprehensive evaluation of fusion transcript detection algorithms and a meta-caller to combine top performing methods in paired-end RNA-seq data. Nucleic Acids Res. 2016 Mar 18;44(5):e47. doi: 10.1093/nar/gkv1234. PubMed PMID: 26582927; PMCID: PMC4797269.
Phong BL, Avery L, Sumpter TL, Gorman JV, Watkins SC, Colgan JD, Kane LP. Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation. J Exp Med. 2015 Dec 14;212(13):2289-304. doi: 10.1084/jem.20150388. PubMed PMID: 26598760; PMCID: PMC4689164.
Zou C, Synan MJ, Li J, Xiong S, Manni ML, Liu Y, Chen BB, Zhao Y, Shiva S, Tyurina YY, Jiang J, Lee JS, Das S, Ray A, Ray P, Kagan VE, Mallampalli RK. LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1. J Cell Sci. 2016 Jan 1;129(1):51-64. doi: 10.1242/jcs.176701. PubMed PMID: 26604221; PMCID: PMC4732295.
Barneda D, Planas-Iglesias J, Gaspar ML, Mohammadyani D, Prasannan S, Dormann D, Han GS, Jesch SA, Carman GM, Kagan V, Parker MG, Ktistakis NT, Klein-Seetharaman J, Dixon AM, Henry SA, Christian M. The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix. Elife. 2015 Nov 26;4e07485. doi: 10.7554/eLife.07485. PubMed PMID: 26609809; PMCID: PMC4755750.
Bogdanova TI, Zurnadzhy LY, Nikiforov YE, Leeman-Neill RJ, Tronko MD, Chanock S, Mabuchi K, Likhtarov IA, Kovgan LM, Drozdovitch V, Little MP, Hatch M, Zablotska LB, Shpak VM, McConnell RJ, Brenner AV. Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort. Br J Cancer. 2015 Dec 1;113(11):1556-64. doi: 10.1038/bjc.2015.372. PubMed PMID: 26625214; PMCID: PMC4705885.
Nikiforov YE. Thyroid cancer in 2015: Molecular landscape of thyroid cancer continues to be deciphered. Nat Rev Endocrinol. 2016 Feb;12(2):67-8. doi: 10.1038/nrendo.2015.217. PubMed PMID: 26668120.
Pasta S, Phillippi JA, Tsamis A, D'Amore A, Raffa GM, Pilato M, Scardulla C, Watkins SC, Wagner WR, Gleason TG, Vorp DA. Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters. Med Eng Phys. 2016 Feb;38(2):121-30. doi: 10.1016/j.medengphy.2015.11.001. PubMed PMID: 26669606; PMCID: PMC4755864.
Nikiforova MN, Wald AI, Melan MA, Roy S, Zhong S, Hamilton RL, Lieberman FS, Drappatz J, Amankulor NM, Pollack IF, Nikiforov YE, Horbinski C. Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors. Neuro Oncol. 2016 Mar;18(3):379-87. doi: 10.1093/neuonc/nov289. PubMed PMID: 26681766; PMCID: PMC4767245.
Simons M, Pollard MR, Hughes CD, Ward AD, Van Houten B, Towrie M, Botchway SW, Parker AW, Kad NM. Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optically trapped nanoprobe. Sci Rep. 2015 Dec 22;518486. doi: 10.1038/srep18486. PubMed PMID: 26691010; PMCID: PMC4686980.
Mao G, Qu F, St Croix CM, Tyurina YY, Planas-Iglesias J, Jiang J, Huang Z, Amoscato AA, Tyurin VA, Kapralov AA, Cheikhi A, Maguire J, Klein-Seetharaman J, Bayır H, Kagan VE. Mitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals. ACS Chem Biol. 2016 Feb 19;11(2):530-40. doi: 10.1021/acschembio.5b00737. PubMed PMID: 26697918; PMCID: PMC5741079.
Bostanci Z, Mack RP Jr, Enomoto LM, Alam S, Brown A, Neumann C, Soybel DI, Kelleher SL. Marginal zinc intake reduces the protective effect of lactation on mammary gland carcinogenesis in a DMBA-induced tumor model in mice. Oncol Rep. 2016 Mar;35(3):1409-16. doi: 10.3892/or.2015.4508. PubMed PMID: 26707944.
Van Houten B, Hunter SE, Meyer JN. Mitochondrial DNA damage induced autophagy, cell death, and disease. Front Biosci (Landmark Ed). 2016 Jan 1;2142-54. doi: 10.2741/4375. PubMed PMID: 26709760; PMCID: PMC4750375.
Xie Y, Wang H, Cheng X, Wu Y, Cao L, Wu M, Xie W, Wang G, Hao H. Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming. Sci Rep. 2016 Jan 5;618751. doi: 10.1038/srep18751. PubMed PMID: 26728993; PMCID: PMC4700422.
Böhm S, Szakal B, Herken BW, Sullivan MR, Mihalevic MJ, Kabbinavar FF, Branzei D, Clark NL, Bernstein KA. The Budding Yeast Ubiquitin Protease Ubp7 Is a Novel Component Involved in S Phase Progression. J Biol Chem. 2016 Feb 26;291(9):4442-52. doi: 10.1074/jbc.M115.671057. PubMed PMID: 26740628; PMCID: PMC4813472.
Tong GX, Chang Q, Hamele-Bena D, Carew J, Hoffman RS, Nikiforova MN, Nikiforov YE. Targeted Next-Generation Sequencing Analysis of a Pendred Syndrome-Associated Thyroid Carcinoma. Endocr Pathol. 2016 Mar;27(1):70-5. doi: 10.1007/s12022-015-9413-4. PubMed PMID: 26744121.
Beadling C, Wald AI, Warrick A, Neff TL, Zhong S, Nikiforov YE, Corless CL, Nikiforova MN. A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing. J Mol Diagn. 2016 Mar;18(2):165-75. doi: 10.1016/j.jmoldx.2015.10.002. PubMed PMID: 26747586.
Vlasova II, Kapralov AA, Michael ZP, Burkert SC, Shurin MR, Star A, Shvedova AA, Kagan VE. Enzymatic oxidative biodegradation of nanoparticles: Mechanisms, significance and applications. Toxicol Appl Pharmacol. 2016 May 15;29958-69. doi: 10.1016/j.taap.2016.01.002. PubMed PMID: 26768553; PMCID: PMC4811710.
Greenberger J, Kagan V, Bayir H, Wipf P, Epperly M. Antioxidant Approaches to Management of Ionizing Irradiation Injury. Antioxidants (Basel). 2015 Jan 23;4(1):82-101. doi: 10.3390/antiox4010082. PubMed PMID: 26785339; PMCID: PMC4665573.
Prasad ML, Vyas M, Horne MJ, Virk RK, Morotti R, Liu Z, Tallini G, Nikiforova MN, Christison-Lagay ER, Udelsman R, Dinauer CA, Nikiforov YE. NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States. Cancer. 2016 Apr 1;122(7):1097-107. doi: 10.1002/cncr.29887. PubMed PMID: 26784937.
Shinde A, Berhane H, Rhieu BH, Kalash R, Xu K, Goff J, Epperly MW, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Parmar K, Guinan E, Kagan V, Tyurin V, Ferris RL, Zhang X, Li S, Greenberger JS. Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(-/-) (C57BL/6) Mice. Radiat Res. 2016 Feb;185(2):134-50. doi: 10.1667/RR14035.1. PubMed PMID: 26789701; PMCID: PMC4773657.
Mehta K, Appleman L, Wang H, Tarhini AA, Parikh RA. Annual Hospital Volume of High Dose Interleukin-2 and Inpatient Mortality in Melanoma and Renal Cell Carcinoma Patients. PLoS One. 2016;11(1):e0147153. doi: 10.1371/journal.pone.0147153. PubMed PMID: 26799322; PMCID: PMC4723120.
Huang Z, Epperly M, Watkins SC, Greenberger JS, Kagan VE, Bayır H. Necrostatin-1 rescues mice from lethal irradiation. Biochim Biophys Acta. 2016 Apr;1862(4):850-856. doi: 10.1016/j.bbadis.2016.01.014. PubMed PMID: 26802452; PMCID: PMC4788560.
Godin SK, Lee AG, Baird JM, Herken BW, Bernstein KA. Tryptophan biosynthesis is important for resistance to replicative stress in Saccharomyces cerevisiae. Yeast. 2016 May;33(5):183-9. doi: 10.1002/yea.3150. PubMed PMID: 26804060; PMCID: PMC4856547.
He J, Wang Y, Missinato MA, Onuoha E, Perkins LA, Watkins SC, St Croix CM, Tsang M, Bruchez MP. A genetically targetable near-infrared photosensitizer. Nat Methods. 2016 Mar;13(3):263-8. doi: 10.1038/nmeth.3735. PubMed PMID: 26808669; PMCID: PMC4916159.
Kaur P, Wu D, Lin J, Countryman P, Bradford KC, Erie DA, Riehn R, Opresko PL, Wang H. Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2. Sci Rep. 2016 Feb 9;620513. doi: 10.1038/srep20513. PubMed PMID: 26856421; PMCID: PMC4746636.
Pinilla-Macua I, Watkins SC, Sorkin A. Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2122-7. doi: 10.1073/pnas.1520301113. PubMed PMID: 26858456; PMCID: PMC4776482.
Gurda GT, Ambros T, Nikiforova MN, Nikiforov YE, Lucas PC, Dabbs DJ, Lee AV, Brufsky AM, Puhalla SL, Bhargava R. Characterizing Molecular Variants and Clinical Utilization of Next-generation Sequencing in Advanced Breast Cancer. Appl Immunohistochem Mol Morphol. 2017 Jul;25(6):392-398. doi: 10.1097/PAI.0000000000000322. PubMed PMID: 26862949.
Roy S, LaFramboise WA, Nikiforov YE, Nikiforova MN, Routbort MJ, Pfeifer J, Nagarajan R, Carter AB, Pantanowitz L. Next-Generation Sequencing Informatics: Challenges and Strategies for Implementation in a Clinical Environment. Arch Pathol Lab Med. 2016 Sep;140(9):958-75. doi: 10.5858/arpa.2015-0507-RA. PubMed PMID: 26901284.
Shvedova A, Pietroiusti A, Kagan V. Nanotoxicology ten years later: Lights and shadows. Toxicol Appl Pharmacol. 2016 May 15;2991-2. doi: 10.1016/j.taap.2016.02.014. PubMed PMID: 26908175; PMCID: PMC5370549.
Gertz RJ, Nikiforov Y, Rehrauer W, McDaniel L, Lloyd RV. Mutation in BRAF and Other Members of the MAPK Pathway in Papillary Thyroid Carcinoma in the Pediatric Population. Arch Pathol Lab Med. 2016 Feb;140(2):134-9. doi: 10.5858/arpa.2014-0612-OA. PubMed PMID: 26910217.
Karunamurthy A, Panebianco F, J Hsiao S, Vorhauer J, Nikiforova MN, Chiosea S, Nikiforov YE. Prevalence and phenotypic correlations of EIF1AX mutations in thyroid nodules. Endocr Relat Cancer. 2016 Apr;23(4):295-301. doi: 10.1530/ERC-16-0043. PubMed PMID: 26911375; PMCID: PMC5494715.
Tejero J, Kapralov AA, Baumgartner MP, Sparacino-Watkins CE, Anthonymutu TS, Vlasova II, Camacho CJ, Gladwin MT, Bayir H, Kagan VE. Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences. Biochim Biophys Acta. 2016 May;1861(5):391-401. doi: 10.1016/j.bbalip.2016.02.022. PubMed PMID: 26928591; PMCID: PMC4821708.
Lee S, Opresko P, Pappo A, Kirkwood JM, Bahrami A. Association of TERT promoter mutations with telomerase expression in melanoma. Pigment Cell Melanoma Res. 2016 May;29(3):391-3. doi: 10.1111/pcmr.12471. PubMed PMID: 26928778; PMCID: PMC5248652.
McClendon TB, Sullivan MR, Bernstein KA, Yanowitz JL. Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans. Genetics. 2016 May;203(1):133-45. doi: 10.1534/genetics.115.185827. PubMed PMID: 26936927; PMCID: PMC4858769.
Chen D, Yu J, Zhang L. Necroptosis: an alternative cell death program defending against cancer. Biochim Biophys Acta. 2016 Apr;1865(2):228-36. doi: 10.1016/j.bbcan.2016.03.003. PubMed PMID: 26968619; PMCID: PMC4860077.
Nikiforov YE, Seethala RR, Tallini G, Baloch ZW, Basolo F, Thompson LD, Barletta JA, Wenig BM, Al Ghuzlan A, Kakudo K, Giordano TJ, Alves VA, Khanafshar E, Asa SL, El-Naggar AK, Gooding WE, Hodak SP, Lloyd RV, Maytal G, Mete O, Nikiforova MN, Nosé V, Papotti M, Poller DN, Sadow PM, Tischler AS, Tuttle RM, Wall KB, LiVolsi VA, Randolph GW, Ghossein RA. Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A Paradigm Shift to Reduce Overtreatment of Indolent Tumors. JAMA Oncol. 2016 Aug 1;2(8):1023-9. doi: 10.1001/jamaoncol.2016.0386. PubMed PMID: 27078145; PMCID: PMC5539411.
Maletta F, Massa F, Torregrossa L, Duregon E, Casadei GP, Basolo F, Tallini G, Volante M, Nikiforov YE, Papotti M. Cytological features of "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" and their correlation with tumor histology. Hum Pathol. 2016 Aug;54134-42. doi: 10.1016/j.humpath.2016.03.014. PubMed PMID: 27085556.
Stoner MW, Thapa D, Zhang M, Gibson GA, Calderon MJ, St Croix CM, Scott I. α-Lipoic acid promotes α-tubulin hyperacetylation and blocks the turnover of mitochondria through mitophagy. Biochem J. 2016 Jun 15;473(12):1821-30. doi: 10.1042/BCJ20160281. PubMed PMID: 27099338; PMCID: PMC6040678.
Wang Y, Wang X, Flores ER, Yu J, Chang S. Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation. Aging Cell. 2016 Aug;15(4):646-60. doi: 10.1111/acel.12476. PubMed PMID: 27113195; PMCID: PMC4933665.
Lu S, Mandava G, Yan G, Lu X. An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem. Algorithms Mol Biol. 2016;1111. doi: 10.1186/s13015-016-0073-9. PubMed PMID: 27148394; PMCID: PMC4855522.
Pham HV, Pantanowitz L, Liu Y. Quantitative phase imaging to improve the diagnostic accuracy of urine cytology. Cancer Cytopathol. 2016 Sep;124(9):641-50. doi: 10.1002/cncy.21734. PubMed PMID: 27177072; PMCID: PMC5026558.
Hodak S, Tuttle RM, Maytal G, Nikiforov YE, Randolph G. Changing the Cancer Diagnosis: The Case of Follicular Variant of Papillary Thyroid Cancer-Primum Non Nocere and NIFTP. Thyroid. 2016 Jul;26(7):869-71. doi: 10.1089/thy.2016.0205. PubMed PMID: 27184034.
Khare A, Raundhal M, Chakraborty K, Das S, Corey C, Kamga CK, Quesnelle K, St Croix C, Watkins SC, Morse C, Oriss TB, Huff R, Hannum R, Ray P, Shiva S, Ray A. Mitochondrial H2O2 in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation. Cell Rep. 2016 May 24;15(8):1700-14. doi: 10.1016/j.celrep.2016.04.060. PubMed PMID: 27184852; PMCID: PMC4880515.
Lu X, Yan C, Huang Y, Shi D, Fu Z, Qiu J, Yin Y. Mouse double minute 2 (MDM2) upregulates Snail expression and induces epithelial-to-mesenchymal transition in breast cancer cells in vitro and in vivo. Oncotarget. 2016 Jun 14;7(24):37177-37191. doi: 10.18632/oncotarget.9287. PubMed PMID: 27184007; PMCID: PMC5095067.
Yu C, Yan S, Khambu B, Chen X, Dong Z, Luo J, Michalopoulos GK, Wu S, Yin XM. Gene Expression Analysis Indicates Divergent Mechanisms in DEN-Induced Carcinogenesis in Wild Type and Bid-Deficient Livers. PLoS One. 2016;11(5):e0155211. doi: 10.1371/journal.pone.0155211. PubMed PMID: 27196317; PMCID: PMC4873180.
Baloch ZW, Seethala RR, Faquin WC, Papotti MG, Basolo F, Fadda G, Randolph GW, Hodak SP, Nikiforov YE, Mandel SJ. Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): A changing paradigm in thyroid surgical pathology and implications for thyroid cytopathology. Cancer Cytopathol. 2016 Sep;124(9):616-20. doi: 10.1002/cncy.21744. PubMed PMID: 27203786.
Opresko PL, Shay JW. Telomere-associated aging disorders. Ageing Res Rev. 2017 Jan;3352-66. doi: 10.1016/j.arr.2016.05.009. PubMed PMID: 27215853.
Godin SK, Sullivan MR, Bernstein KA. Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication. Biochem Cell Biol. 2016 Oct;94(5):407-418. doi: 10.1139/bcb-2016-0012. PubMed PMID: 27224545; PMCID: PMC5045787.
Keskinov AA, Tapias V, Watkins SC, Ma Y, Shurin MR, Shurin GV. Impact of the Sensory Neurons on Melanoma Growth In Vivo. PLoS One. 2016;11(5):e0156095. doi: 10.1371/journal.pone.0156095. PubMed PMID: 27227315; PMCID: PMC4882065.
Moiseeva TN, Gamper AM, Hood BL, Conrads TP, Bakkenist CJ. Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. DNA Repair (Amst). 2016 Jul;439-17. doi: 10.1016/j.dnarep.2016.04.007. PubMed PMID: 27235625; PMCID: PMC4917431.
Buland JR, Wasserloos KJ, Tyurin VA, Tyurina YY, Amoscato AA, Mallampalli RK, Chen BB, Zhao J, Zhao Y, Ofori-Acquah S, Kagan VE, Pitt BR. Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L303-16. doi: 10.1152/ajplung.00038.2016. PubMed PMID: 27233995; PMCID: PMC5142456.
Fouquerel E, Parikh D, Opresko P. DNA damage processing at telomeres: The ends justify the means. DNA Repair (Amst). 2016 Aug;44159-168. doi: 10.1016/j.dnarep.2016.05.022. PubMed PMID: 27233113.
Ma L, Umasankar PK, Wrobel AG, Lymar A, McCoy AJ, Holkar SS, Jha A, Pradhan-Sundd T, Watkins SC, Owen DJ, Traub LM. Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding. Dev Cell. 2016 Jun 6;37(5):428-43. doi: 10.1016/j.devcel.2016.05.003. PubMed PMID: 27237791; PMCID: PMC4921775.
Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ. ATM protein is deficient in over 40% of lung adenocarcinomas. Oncotarget. 2016 Sep 6;7(36):57714-57725. doi: 10.18632/oncotarget.9757. PubMed PMID: 27259260; PMCID: PMC5295384.
Houten BV, Kuper J, Kisker C. Role of XPD in cellular functions: To TFIIH and beyond. DNA Repair (Amst). 2016 Aug;44136-142. doi: 10.1016/j.dnarep.2016.05.019. PubMed PMID: 27262611.
Hagos FT, Daood MJ, Ocque JA, Nolin TD, Bayir H, Poloyac SM, Kochanek PM, Clark RS, Empey PE. Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine. Xenobiotica. 2017 Apr;47(4):346-353. doi: 10.1080/00498254.2016.1187777. PubMed PMID: 27278858; PMCID: PMC5572076.
Godin SK, Zhang Z, Herken BW, Westmoreland JW, Lee AG, Mihalevic MJ, Yu Z, Sobol RW, Resnick MA, Bernstein KA. The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products. Nucleic Acids Res. 2016 Sep 30;44(17):8199-215. doi: 10.1093/nar/gkw535. PubMed PMID: 27298254; PMCID: PMC5041462.
Lin J, Countryman P, Chen H, Pan H, Fan Y, Jiang Y, Kaur P, Miao W, Gurgel G, You C, Piehler J, Kad NM, Riehn R, Opresko PL, Smith S, Tao YJ, Wang H. Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing. Nucleic Acids Res. 2016 Jul 27;44(13):6363-76. doi: 10.1093/nar/gkw518. PubMed PMID: 27298259; PMCID: PMC5291270.
Scuba W, Tharp M, Mowery D, Tseytlin E, Liu Y, Drews FA, Chapman WW. Knowledge Author: facilitating user-driven, domain content development to support clinical information extraction. J Biomed Semantics. 2016 Jun 23;7(1):42. doi: 10.1186/s13326-016-0086-9. PubMed PMID: 27338146; PMCID: PMC4919842.
He K, Chen D, Ruan H, Li X, Tong J, Xu X, Zhang L, Yu J. BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells. Oncotarget. 2016 Jul 26;7(30):47699-47710. doi: 10.18632/oncotarget.10277. PubMed PMID: 27351224; PMCID: PMC5216972.
Zerbato JM, Serrao E, Lenzi G, Kim B, Ambrose Z, Watkins SC, Engelman AN, Sluis-Cremer N. Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro. J Virol. 2016 Sep 15;90(18):8059-73. doi: 10.1128/JVI.00553-16. PubMed PMID: 27356901; PMCID: PMC5008097.
Sehrawat A, Croix CS, Baty CJ, Watkins S, Tailor D, Singh RP, Singh SV. Inhibition of mitochondrial fusion is an early and critical event in breast cancer cell apoptosis by dietary chemopreventative benzyl isothiocyanate. Mitochondrion. 2016 Sep;3067-77. doi: 10.1016/j.mito.2016.06.006. PubMed PMID: 27374852; PMCID: PMC5023488.
Poller DN, Nikiforov YE. Non-invasive follicular thyroid neoplasm with papillary-like nuclei: reducing overtreatment by reclassifying an indolent variant of papillary thyroid cancer. J Clin Pathol. 2016 Jul 7; doi: 10.1136/jclinpath-2016-203930. PubMed PMID: 27387983.
Singhi AD, Liu TC, Roncaioli JL, Cao D, Zeh HJ, Zureikat AH, Tsung A, Marsh JW, Lee KK, Hogg ME, Bahary N, Brand RE, McGrath KM, Slivka A, Cressman KL, Fuhrer K, O'Sullivan RJ. Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors. Clin Cancer Res. 2017 Jan 15;23(2):600-609. doi: 10.1158/1078-0432.CCR-16-1113. PubMed PMID: 27407094; PMCID: PMC6560642.
Tippana R, Hwang H, Opresko PL, Bohr VA, Myong S. Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8448-53. doi: 10.1073/pnas.1603724113. PubMed PMID: 27407146; PMCID: PMC4968719.
Raupach EA, Martens JA, Arndt KM. Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic Transcription in Saccharomyces cerevisiae. G3 (Bethesda). 2016 Sep 8;6(9):2971-81. doi: 10.1534/g3.116.033118. PubMed PMID: 27449519; PMCID: PMC5015954.
Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. doi: 10.1073/pnas.1603883113. PubMed PMID: 27450084; PMCID: PMC4987817.
Kao YC, Sung YS, Zhang L, Huang SC, Argani P, Chung CT, Graf NS, Wright DC, Kellie SJ, Agaram NP, Ludwig K, Zin A, Alaggio R, Antonescu CR. Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy: Overlapping Genetic Features With Clear Cell Sarcoma of Kidney. Am J Surg Pathol. 2016 Aug;40(8):1009-20. doi: 10.1097/PAS.0000000000000629. PubMed PMID: 26945340; PMCID: PMC4942366.
Maguire JJ, Tyurina YY, Mohammadyani D, Kapralov AA, Anthonymuthu TS, Qu F, Amoscato AA, Sparvero LJ, Tyurin VA, Planas-Iglesias J, He RR, Klein-Seetharaman J, Bayır H, Kagan VE. Known unknowns of cardiolipin signaling: The best is yet to come. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jan;1862(1):8-24. doi: 10.1016/j.bbalip.2016.08.001. PubMed PMID: 27498292; PMCID: PMC5323096.
Scharping NE, Menk AV, Moreci RS, Whetstone RD, Dadey RE, Watkins SC, Ferris RL, Delgoffe GM. The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction. Immunity. 2016 Aug 16;45(2):374-88. doi: 10.1016/j.immuni.2016.07.009. PubMed PMID: 27496732; PMCID: PMC5207350.
Sallmyr A, Matsumoto Y, Roginskaya V, Van Houten B, Tomkinson AE. Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells. Cancer Res. 2016 Sep 15;76(18):5431-41. doi: 10.1158/0008-5472.CAN-15-3243. PubMed PMID: 27503931; PMCID: PMC5036517.
Cucinotta CE, Arndt KM. SnapShot: Transcription Elongation. Cell. 2016 Aug 11;166(4):1058-1058.e1. doi: 10.1016/j.cell.2016.07.039. PubMed PMID: 27518568.
Nikiforov YE. Ramifications of New Terminology for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma-Reply. JAMA Oncol. 2016 Aug 1;2(8):1098-9. doi: 10.1001/jamaoncol.2016.2205. PubMed PMID: 27533609.
Helfield B, Chen X, Watkins SC, Villanueva FS. Biophysical insight into mechanisms of sonoporation. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9983-8. doi: 10.1073/pnas.1606915113. PubMed PMID: 27551081; PMCID: PMC5018802.
Martino J, Bernstein KA. The Shu complex is a conserved regulator of homologous recombination. FEMS Yeast Res. 2016 Sep;16(6): doi: 10.1093/femsyr/fow073. PubMed PMID: 27589940; PMCID: PMC5976032.
Chen Q, Qin S, Liu Y, Hong M, Qian CN, Keller ET, Zhang J, Lu Y. IGFBP6 is a novel nasopharyngeal carcinoma prognostic biomarker. Oncotarget. 2016 Oct 18;7(42):68140-68150. doi: 10.18632/oncotarget.11886. PubMed PMID: 27623076; PMCID: PMC5356544.
Manos-Turvey A, Al-Ashtal HA, Needham PG, Hartline CB, Prichard MN, Wipf P, Brodsky JL. Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5087-5091. doi: 10.1016/j.bmcl.2016.08.080. PubMed PMID: 27624078; PMCID: PMC5050167.
Zhang X, Hou W, Epperly MW, Rigatti L, Wang H, Franicola D, Sivanathan A, Greenberger JS. Evolution of malignant plasmacytoma cell lines from K14E7 Fancd2-/- mouse long-term bone marrow cultures. Oncotarget. 2016 Oct 18;7(42):68449-68472. doi: 10.18632/oncotarget.12036. PubMed PMID: 27637088; PMCID: PMC5356567.
Chiosea S, Asa SL, Berman MA, Carty SE, Currence L, Hodak S, Nikiforov YE, Richardson MS, Seethala RR, Sholl LM, Thompson LD, Wenig BM, Worden F, Members of the Cancer Biomarker Reporting Committee, College of American Pathologists.. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Thyroid Carcinoma. Arch Pathol Lab Med. 2017 Apr;141(4):559-563. doi: 10.5858/arpa.2016-0326-CP. PubMed PMID: 27681332.
Klei LR, Hu D, Panek R, Alfano DN, Bridwell RE, Bailey KM, Oravecz-Wilson KI, Concel VJ, Hess EM, Van Beek M, Delekta PC, Gu S, Watkins SC, Ting AT, Gough PJ, Foley KP, Bertin J, McAllister-Lucas LM, Lucas PC. MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage. Cell Rep. 2016 Sep 27;17(1):221-232. doi: 10.1016/j.celrep.2016.08.080. PubMed PMID: 27681433; PMCID: PMC5087334.
Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016 Oct 4;712885. doi: 10.1038/ncomms12885. PubMed PMID: 27698350; PMCID: PMC5059456.
Kelly NJ, Dandachi N, Goncharov DA, Pena AZ, Radder JE, Gregory AD, Lai YC, Leme AS, Gladwin MT, Goncharova EA, St Croix CM, Shapiro SD. Automated Measurement of Blood Vessels in Tissues from Microscopy Images. Curr Protoc Cytom. 2016 Oct 10;7812.44.1-12.44.13. doi: 10.1002/cpcy.10. PubMed PMID: 27723088; PMCID: PMC6431235.
Lu S, Cai C, Yan G, Zhou Z, Wan Y, Chen V, Chen L, Cooper GF, Obeid LM, Hannun YA, Lee AV, Lu X. Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations. Cancer Res. 2016 Dec 1;76(23):6785-6794. doi: 10.1158/0008-5472.CAN-16-1740. PubMed PMID: 27758891; PMCID: PMC5165695.
Kong M, Liu L, Chen X, Driscoll KI, Mao P, Böhm S, Kad NM, Watkins SC, Bernstein KA, Wyrick JJ, Min JH, Van Houten B. Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition Process. Mol Cell. 2016 Oct 20;64(2):376-387. doi: 10.1016/j.molcel.2016.09.005. PubMed PMID: 27720644; PMCID: PMC5123691.
Van Der Kraak L, Goel G, Ramanan K, Kaltenmeier C, Zhang L, Normolle DP, Freeman GJ, Tang D, Nason KS, Davison JM, Luketich JD, Dhupar R, Lotze MT. 5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers. J Immunother Cancer. 2016;465. doi: 10.1186/s40425-016-0163-8. PubMed PMID: 27777774; PMCID: PMC5067917.
Ouyang Y, Bayer A, Chu T, Tyurin VA, Kagan VE, Morelli AE, Coyne CB, Sadovsky Y. Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity. Placenta. 2016 Nov;4786-95. doi: 10.1016/j.placenta.2016.09.008. PubMed PMID: 27780544; PMCID: PMC5123854.
Brand RM, Epperly MW, Stottlemyer JM, Skoda EM, Gao X, Li S, Huq S, Wipf P, Kagan VE, Greenberger JS, Falo LD Jr. A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage. J Invest Dermatol. 2017 Mar;137(3):576-586. doi: 10.1016/j.jid.2016.09.033. PubMed PMID: 27794421; PMCID: PMC5466072.
Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL. Oxidative guanine base damage regulates human telomerase activity. Nat Struct Mol Biol. 2016 Dec;23(12):1092-1100. doi: 10.1038/nsmb.3319. PubMed PMID: 27820808; PMCID: PMC5140714.
Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ. Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres. Cell Rep. 2016 Nov 8;17(7):1858-1871. doi: 10.1016/j.celrep.2016.10.048. PubMed PMID: 27829156; PMCID: PMC5406014.
Van Oss SB, Shirra MK, Bataille AR, Wier AD, Yen K, Vinayachandran V, Byeon IL, Cucinotta CE, Héroux A, Jeon J, Kim J, VanDemark AP, Pugh BF, Arndt KM. The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6. Mol Cell. 2016 Nov 17;64(4):815-825. doi: 10.1016/j.molcel.2016.10.008. PubMed PMID: 27840029; PMCID: PMC5131541.
Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nat Chem Biol. 2017 Jan;13(1):81-90. doi: 10.1038/nchembio.2238. PubMed PMID: 27842066; PMCID: PMC5506843.
Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. PubMed PMID: 27842070; PMCID: PMC5610546.
Kad NM, Van Houten B. DNA repair: Clamping down on copy errors. Nature. 2016 Nov 24;539(7630):498-499. doi: 10.1038/nature20475. PubMed PMID: 27851733; PMCID: PMC5641404.
Patel SG, Carty SE, McCoy KL, Ohori NP, LeBeau SO, Seethala RR, Nikiforova MN, Nikiforov YE, Yip L. Preoperative detection of RAS mutation may guide extent of thyroidectomy. Surgery. 2017 Jan;161(1):168-175. doi: 10.1016/j.surg.2016.04.054. PubMed PMID: 27863786; PMCID: PMC5497309.
Fouquerel E, Opresko PL. Convergence of The Nobel Fields of Telomere Biology and DNA Repair. Photochem Photobiol. 2017 Jan;93(1):229-237. doi: 10.1111/php.12672. PubMed PMID: 27861975; PMCID: PMC5315637.
Kao YC, Sung YS, Zhang L, Jungbluth AA, Huang SC, Argani P, Agaram NP, Zin A, Alaggio R, Antonescu CR. BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic Abnormalities. Am J Surg Pathol. 2016 Dec;40(12):1670-1678. doi: 10.1097/PAS.0000000000000697. PubMed PMID: 27428733; PMCID: PMC5106294.
Shah AA, La Fortune K, Miller C, Mills SE, Baloch Z, LiVolsi V, Dacic S, Mahaffey AL, Nikiforova M, Nikiforov YE, Seethala RR. Thyroid sclerosing mucoepidermoid carcinoma with eosinophilia: a clinicopathologic and molecular analysis of a distinct entity. Mod Pathol. 2017 Mar;30(3):329-339. doi: 10.1038/modpathol.2016.180. PubMed PMID: 27910944; PMCID: PMC5497311.
Buck TM, Jordahl AS, Yates ME, Preston GM, Cook E, Kleyman TR, Brodsky JL. Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein. Biochem J. 2017 Feb 1;474(3):357-376. doi: 10.1042/BCJ20160760. PubMed PMID: 27903760; PMCID: PMC5423784.
Kong M, Van Houten B. Rad4 recognition-at-a-distance: Physical basis of conformation-specific anomalous diffusion of DNA repair proteins. Prog Biophys Mol Biol. 2017 Aug;12793-104. doi: 10.1016/j.pbiomolbio.2016.12.004. PubMed PMID: 27939760; PMCID: PMC5462892.
Weidhaas JB, Harris J, Schaue D, Chen AM, Chin R, Axelrod R, El-Naggar AK, Singh AK, Galloway TJ, Raben D, Wang D, Matthiesen C, Avizonis VN, Manon RR, Yumen O, Nguyen-Tan PF, Trotti A, Skinner H, Zhang Q, Ferris RL, Sidransky D, Chung CH. The KRAS-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2017 Apr 1;3(4):483-491. doi: 10.1001/jamaoncol.2016.5478. PubMed PMID: 28006059; PMCID: PMC5470422.
Braganza A, Li J, Zeng X, Yates NA, Dey NB, Andrews J, Clark J, Zamani L, Wang XH, St Croix C, O'Sullivan R, Garcia-Exposito L, Brodsky JL, Sobol RW. UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase. J Biol Chem. 2017 Feb 10;292(6):2470-2484. doi: 10.1074/jbc.M116.766824. PubMed PMID: 28003368; PMCID: PMC5313114.
Mischler SE, Cauda EG, Di Giuseppe M, McWilliams LJ, St Croix C, Sun M, Franks J, Ortiz LA. Differential activation of RAW 264.7 macrophages by size-segregated crystalline silica. J Occup Med Toxicol. 2016;1157. doi: 10.1186/s12995-016-0145-2. PubMed PMID: 28018477; PMCID: PMC5159951.
Li X, Li M, Ruan H, Qiu W, Xu X, Zhang L, Yu J. Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress. Oncotarget. 2017 Feb 7;8(6):9280-9292. doi: 10.18632/oncotarget.14063. PubMed PMID: 28030835; PMCID: PMC5354731.
Zhou Z, Luo A, Shrivastava I, He M, Huang Y, Bahar I, Liu Z, Wan Y. Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis. EBioMedicine. 2017 Feb;1548-61. doi: 10.1016/j.ebiom.2016.12.014. PubMed PMID: 28040451; PMCID: PMC5233825.
Zhao J, Fuhrmann-Stroissnigg H, Gurkar AU, Flores RR, Dorronsoro A, Stolz DB, St Croix CM, Niedernhofer LJ, Robbins PD. Quantitative Analysis of Cellular Senescence in Culture and In Vivo. Curr Protoc Cytom. 2017 Jan 5;799.51.1-9.51.25. doi: 10.1002/cpcy.16. PubMed PMID: 28055114.
Epperly MW, Sacher JR, Krainz T, Zhang X, Wipf P, Liang M, Fisher R, Li S, Wang H, Greenberger JS. Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators. In Vivo. 2017 Jan 2;31(1):39-43. doi: 10.21873/invivo.11022. PubMed PMID: 28064218; PMCID: PMC5267945.
Huang Y, Davidson NE. Targeting tumorigenicity of breast cancer stem-like cells using combination epigenetic therapy: something old and something new. J Thorac Dis. 2016 Nov;8(11):2971-2974. doi: 10.21037/jtd.2016.11.18. PubMed PMID: 28066560; PMCID: PMC5179425.
Lehman CE, Dillon LW, Nikiforov YE, Wang YH. DNA fragile site breakage as a measure of chemical exposure and predictor of individual susceptibility to form oncogenic rearrangements. Carcinogenesis. 2017 Mar 1;38(3):293-301. doi: 10.1093/carcin/bgw210. PubMed PMID: 28069693; PMCID: PMC5862292.
Yilmaz E, Watkins SC, Gold MS. Paclitaxel-induced increase in mitochondrial volume mediates dysregulation of intracellular Ca2+ in putative nociceptive glabrous skin neurons from the rat. Cell Calcium. 2017 Mar;6216-28. doi: 10.1016/j.ceca.2017.01.005. PubMed PMID: 28109678; PMCID: PMC5365154.
Wang Y, Ballou B, Schmidt BF, Andreko S, St Croix CM, Watkins SC, Bruchez MP. Affibody-targeted fluorogen activating protein for in vivo tumor imaging. Chem Commun (Camb). 2017 Feb 7;53(12):2001-2004. doi: 10.1039/c6cc09137g. PubMed PMID: 28120951; PMCID: PMC5340305.
Luo J, Kong M, Liu L, Samanta S, Van Houten B, Deiters A. Optical Control of DNA Helicase Function through Genetic Code Expansion. Chembiochem. 2017 Mar 2;18(5):466-469. doi: 10.1002/cbic.201600624. PubMed PMID: 28120472; PMCID: PMC5516474.
Adamik J, Jin S, Sun Q, Zhang P, Weiss KR, Anderson JL, Silbermann R, Roodman GD, Galson DL. EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation. Mol Cancer Res. 2017 Apr;15(4):405-417. doi: 10.1158/1541-7786.MCR-16-0242-T. PubMed PMID: 28119431; PMCID: PMC5524543.
Seethala RR, Chiosea SI, Liu CZ, Nikiforova M, Nikiforov YE. Clinical and Morphologic Features of ETV6-NTRK3 Translocated Papillary Thyroid Carcinoma in an Adult Population Without Radiation Exposure. Am J Surg Pathol. 2017 Apr;41(4):446-457. doi: 10.1097/PAS.0000000000000814. PubMed PMID: 28125451; PMCID: PMC5384267.
Peng Y, Zhang X, Ma Q, Yan R, Qin Y, Zhao Y, Cheng Y, Yang M, Wang Q, Feng X, Huang Y, Huang W, Zhao Z, Wang L, Wei Y, He Z, Fan X, Li S, Jin Z, Meltzer SJ. MiRNA-194 activates the Wnt/β-catenin signaling pathway in gastric cancer by targeting the negative Wnt regulator, SUFU. Cancer Lett. 2017 Jan 28;385117-127. doi: 10.1016/j.canlet.2016.10.035. PubMed PMID: 27810403.
Vendetti FP, Leibowitz BJ, Barnes J, Schamus S, Kiesel BF, Abberbock S, Conrads T, Clump DA, Cadogan E, O'Connor MJ, Yu J, Beumer JH, Bakkenist CJ. Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation. Sci Rep. 2017 Feb 1;741892. doi: 10.1038/srep41892. PubMed PMID: 28145510; PMCID: PMC5286430.
Preston GM, Brodsky JL. The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation. Biochem J. 2017 Feb 15;474(4):445-469. doi: 10.1042/BCJ20160582. PubMed PMID: 28159894; PMCID: PMC5425155.
Ohori NP, Seethala RR, Nikiforov YE. Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary-like nuclear features. Cancer Cytopathol. 2017 Apr;125(4):292-293. doi: 10.1002/cncy.21830. PubMed PMID: 28170166.
Montecalvo A, Watkins SC, Orange J, Kane LP. Inducible turnover of optineurin regulates T cell activation. Mol Immunol. 2017 May;859-17. doi: 10.1016/j.molimm.2017.01.027. PubMed PMID: 28192730; PMCID: PMC5385146.
Panebianco F, Kelly LM, Liu P, Zhong S, Dacic S, Wang X, Singhi AD, Dhir R, Chiosea SI, Kuan SF, Bhargava R, Dabbs D, Trivedi S, Gandhi M, Diaz R, Wald AI, Carty SE, Ferris RL, Lee AV, Nikiforova MN, Nikiforov YE. THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2307-2312. doi: 10.1073/pnas.1614265114. PubMed PMID: 28193878; PMCID: PMC5338560.
Tong J, Wang P, Tan S, Chen D, Nikolovska-Coleska Z, Zou F, Yu J, Zhang L. Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells. Cancer Res. 2017 May 1;77(9):2512-2521. doi: 10.1158/0008-5472.CAN-16-3242. PubMed PMID: 28202514; PMCID: PMC5626525.
Kiesel BF, Shogan JC, Rachid M, Parise RA, Vendetti FP, Bakkenist CJ, Beumer JH. LC-MS/MS assay for the simultaneous quantitation of the ATM inhibitor AZ31 and the ATR inhibitor AZD6738 in mouse plasma. J Pharm Biomed Anal. 2017 May 10;138158-165. doi: 10.1016/j.jpba.2017.01.055. PubMed PMID: 28213176; PMCID: PMC5357441.
Kagan VE, Bayır H, Tyurina YY, Bolevich SB, Maguire JJ, Fadeel B, Balasubramanian K. Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids. Biochem Biophys Res Commun. 2017 Jan 15;482(3):482-490. doi: 10.1016/j.bbrc.2016.11.005. PubMed PMID: 28212735; PMCID: PMC5319735.
Muthuswamy R, Okada NJ, Jenkins FJ, McGuire K, McAuliffe PF, Zeh HJ, Bartlett DL, Wallace C, Watkins S, Henning JD, Bovbjerg DH, Kalinski P. Epinephrine promotes COX-2-dependent immune suppression in myeloid cells and cancer tissues. Brain Behav Immun. 2017 May;6278-86. doi: 10.1016/j.bbi.2017.02.008. PubMed PMID: 28212885.
Zhang Y, Hu K, Beumer JH, Bakkenist CJ, D'Argenio DZ. RAD-ADAPT: Software for modelling clonogenic assay data in radiation biology. DNA Repair (Amst). 2017 Apr;5224-30. doi: 10.1016/j.dnarep.2017.02.004. PubMed PMID: 28254357; PMCID: PMC5396547.
Epperly MW, Rhieu BH, Franicola D, Dixon T, Cao S, Zhang X, Shields D, Wang H, Wipf P, Greenberger JS. Induction of TGF-β by Irradiation or Chemotherapy in Fanconi Anemia (FA) Mouse Bone Marrow Is Modulated by Small Molecule Radiation Mitigators JP4-039 and MMS350. In Vivo. 2017 Mar-Apr;31(2):159-168. doi: 10.21873/invivo.11040. PubMed PMID: 28358695; PMCID: PMC5411740.
Huang Y, Zhu H. Protein Array-based Approaches for Biomarker Discovery in Cancer. Genomics Proteomics Bioinformatics. 2017 Apr;15(2):73-81. doi: 10.1016/j.gpb.2017.03.001. PubMed PMID: 28392481; PMCID: PMC5414965.
Franks J, Wallace CT, Shibata M, Suga M, Erdman N, Stolz DB, Watkins SC. Correlative Fluorescence and Electron Microscopy in 3D-Scanning Electron Microscope Perspective. Curr Protoc Cytom. 2017 Apr 3;8012.45.1-12.45.15. doi: 10.1002/cpcy.18. PubMed PMID: 28369763.
Capello M, Bantis LE, Scelo G, Zhao Y, Li P, Dhillon DS, Patel NJ, Kundnani DL, Wang H, Abbruzzese JL, Maitra A, Tempero MA, Brand R, Firpo MA, Mulvihill SJ, Katz MH, Brennan P, Feng Z, Taguchi A, Hanash SM. Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 Apr 1;109(4): doi: 10.1093/jnci/djw266. PubMed PMID: 28376157; PMCID: PMC5441297.
Hopkins BL, Nadler M, Skoko JJ, Bertomeu T, Pelosi A, Shafaei PM, Levine K, Schempf A, Pennarun B, Yang B, Datta D, Bucur O, Ndebele K, Oesterreich S, Yang D, Giulia Rizzo M, Khosravi-Far R, Neumann CA. A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7. Antioxid Redox Signal. 2018 Jan 1;28(1):62-77. doi: 10.1089/ars.2016.6871. PubMed PMID: 28398822; PMCID: PMC5695745.
Liu D, Wang H, Schwender H, Marazita ML, Wang Z, Yuan Y, Wang P, Liang KY, Wu-Chou YH, Wang M, Shi B, Zhu H, Wu T, Beaty TH. Gene-gene interaction of single nucleotide polymorphisms in 16p13.3 may contribute to the risk of non-syndromic cleft lip with or without cleft palate in Chinese case-parent trios. Am J Med Genet A. 2017 Jun;173(6):1489-1494. doi: 10.1002/ajmg.a.38190. PubMed PMID: 28402597; PMCID: PMC5559727.
Gao Y, Li C, Wei L, Teng Y, Nakajima S, Chen X, Xu J, Leger B, Ma H, Spagnol ST, Wan Y, Dahl KN, Liu Y, Levine AS, Lan L. SSRP1 Cooperates with PARP and XRCC1 to Facilitate Single-Strand DNA Break Repair by Chromatin Priming. Cancer Res. 2017 May 15;77(10):2674-2685. doi: 10.1158/0008-5472.CAN-16-3128. PubMed PMID: 28416484; PMCID: PMC5500382.
Quang TT, Kim HY, Bao FS, Papay FA, Edwards WB, Liu Y. Fluorescence Imaging Topography Scanning System for intraoperative multimodal imaging. PLoS One. 2017;12(4):e0174928. doi: 10.1371/journal.pone.0174928. PubMed PMID: 28437441; PMCID: PMC5402944.
Epperly MW, Zhang X, Fisher R, Hou W, Franicola D, Shields D, Quickel M, Hankey-Giblin P, Wang H, Greenberger JS. Reduced Competitive Repopulation Capacity of Multipotential Hematopoietic Stem Cells in the Bone Marrow of Friend Virus-infected Fv2-resistant Mice. In Vivo. 2017 May-Jun;31(3):313-320. doi: 10.21873/invivo.11061. PubMed PMID: 28438857; PMCID: PMC5461439.
Chiu CF, Dar HH, Kapralov AA, Robinson RAS, Kagan VE, Star A. Nanoemitters and innate immunity: the role of surfactants and bio-coronas in myeloperoxidase-catalyzed oxidation of pristine single-walled carbon nanotubes. Nanoscale. 2017 May 11;9(18):5948-5956. doi: 10.1039/c6nr07706d. PubMed PMID: 28440832; PMCID: PMC6584033.
Vujanovic L, Stahl EC, Pardee AD, Geller DA, Tsung A, Watkins SC, Gibson GA, Storkus WJ, Butterfield LH. Tumor-Derived α-Fetoprotein Directly Drives Human Natural Killer-Cell Activation and Subsequent Cell Death. Cancer Immunol Res. 2017 Jun;5(6):493-502. doi: 10.1158/2326-6066.CIR-16-0216. PubMed PMID: 28468916.
Zhong L, Liu Y, Han WQ, Huang JY, Mao SX. In Situ Observation of Single-Phase Lithium Intercalation in Sub-25-nm Nanoparticles. Adv Mater. 2017 Jul;29(26): doi: 10.1002/adma.201700236. PubMed PMID: 28474747.
Malapelle U, Mayo-de-Las-Casas C, Molina-Vila MA, Rosell R, Savic S, Bihl M, Bubendorf L, Salto-Tellez M, de Biase D, Tallini G, Hwang DH, Sholl LM, Luthra R, Weynand B, Vander Borght S, Missiaglia E, Bongiovanni M, Stieber D, Vielh P, Schmitt F, Rappa A, Barberis M, Pepe F, Pisapia P, Serra N, Vigliar E, Bellevicine C, Fassan M, Rugge M, de Andrea CE, Lozano MD, Basolo F, Fontanini G, Nikiforov YE, Kamel-Reid S, da Cunha Santos G, Nikiforova MN, Roy-Chowdhuri S, Troncone G, Molecular Cytopathology Meeting Group.. Consistency and reproducibility of next-generation sequencing and other multigene mutational assays: A worldwide ring trial study on quantitative cytological molecular reference specimens. Cancer Cytopathol. 2017 Aug;125(8):615-626. doi: 10.1002/cncy.21868. PubMed PMID: 28475299.
Ma H, Fu R, Xu J, Liu Y. A simple and cost-effective setup for super-resolution localization microscopy. Sci Rep. 2017 May 8;7(1):1542. doi: 10.1038/s41598-017-01606-6. PubMed PMID: 28484239; PMCID: PMC5431525.
Ye Z, Needham PG, Estabrooks SK, Whitaker SK, Garcia BL, Misra S, Brodsky JL, Camacho CJ. Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase. Sci Rep. 2017 May 11;7(1):1789. doi: 10.1038/s41598-017-01880-4. PubMed PMID: 28496195; PMCID: PMC5431976.
Garcia-Exposito L, O'Sullivan RJ. TZAP-ing telomeres down to size. EMBO Rep. 2017 Jun;18(6):861-863. doi: 10.15252/embr.201744354. PubMed PMID: 28500256; PMCID: PMC5452027.
Ma H, Xu J, Jin J, Huang Y, Liu Y. A Simple Marker-Assisted 3D Nanometer Drift Correction Method for Superresolution Microscopy. Biophys J. 2017 May 23;112(10):2196-2208. doi: 10.1016/j.bpj.2017.04.025. PubMed PMID: 28538156; PMCID: PMC5444076.
Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M, Brodsky JL. Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates. Mol Biol Cell. 2017 Jul 15;28(15):2076-2090. doi: 10.1091/mbc.E17-03-0184. PubMed PMID: 28539401; PMCID: PMC5509421.
Kinner-Bibeau LB, Sedlacek AL, Messmer MN, Watkins SC, Binder RJ. HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells. Nat Commun. 2017 May 31;815648. doi: 10.1038/ncomms15648. PubMed PMID: 28561043; PMCID: PMC5460028.
Kondrashova O, Nguyen M, Shield-Artin K, Tinker AV, Teng NNH, Harrell MI, Kuiper MJ, Ho GY, Barker H, Jasin M, Prakash R, Kass EM, Sullivan MR, Brunette GJ, Bernstein KA, Coleman RL, Floquet A, Friedlander M, Kichenadasse G, O'Malley DM, Oza A, Sun J, Robillard L, Maloney L, Bowtell D, Giordano H, Wakefield MJ, Kaufmann SH, Simmons AD, Harding TC, Raponi M, McNeish IA, Swisher EM, Lin KK, Scott CL, AOCS Study Group.. Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma. Cancer Discov. 2017 Sep;7(9):984-998. doi: 10.1158/2159-8290.CD-17-0419. PubMed PMID: 28588062; PMCID: PMC5612362.
Tong J, Tan S, Nikolovska-Coleska Z, Yu J, Zou F, Zhang L. FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors. Mol Cancer Ther. 2017 Sep;16(9):1979-1988. doi: 10.1158/1535-7163.MCT-17-0032. PubMed PMID: 28619760; PMCID: PMC5587378.
Yang S, Zhang L, Thomas S, Hu Y, Li S, Cipollo J, Zhang H. Modification of Sialic Acids on Solid Phase: Accurate Characterization of Protein Sialylation. Anal Chem. 2017 Jun 20;89(12):6330-6335. doi: 10.1021/acs.analchem.7b01048. PubMed PMID: 28505427; PMCID: PMC5583724.
Kong M, Beckwitt EC, Springall L, Kad NM, Van Houten B. Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Time. Methods Enzymol. 2017;592213-257. doi: 10.1016/bs.mie.2017.03.027. PubMed PMID: 28668122; PMCID: PMC5656006.
Beckwitt EC, Kong M, Van Houten B. Studying protein-DNA interactions using atomic force microscopy. Semin Cell Dev Biol. 2018 Jan;73220-230. doi: 10.1016/j.semcdb.2017.06.028. PubMed PMID: 28673677; PMCID: PMC5762137.
Xu J, Ma H, Liu Y. Stochastic Optical Reconstruction Microscopy (STORM). Curr Protoc Cytom. 2017 Jul 5;8112.46.1-12.46.27. doi: 10.1002/cpcy.23. PubMed PMID: 28678417; PMCID: PMC5663316.
Ohori NP, Wolfe J, Carty SE, Yip L, LeBeau SO, Berg AN, Schoedel KE, Nikiforov YE, Seethala RR. The influence of the noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) resection diagnosis on the false-positive thyroid cytology rate relates to quality assurance thresholds and the application of NIFTP criteria. Cancer Cytopathol. 2017 Sep;125(9):692-700. doi: 10.1002/cncy.21892. PubMed PMID: 28678437.
Weinstein AM, Chen L, Brzana EA, Patil PR, Taylor JL, Fabian KL, Wallace CT, Jones SD, Watkins SC, Lu B, Stroncek DF, Denning TL, Fu YX, Cohen PA, Storkus WJ. Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment. Oncoimmunology. 2017;6(6):e1322238. doi: 10.1080/2162402X.2017.1322238. PubMed PMID: 28680760; PMCID: PMC5486180.
Watson AM, Rose AH, Gibson GA, Gardner CL, Sun C, Reed DS, Lam LKM, St Croix CM, Strick PL, Klimstra WB, Watkins SC. Ribbon scanning confocal for high-speed high-resolution volume imaging of brain. PLoS One. 2017;12(7):e0180486. doi: 10.1371/journal.pone.0180486. PubMed PMID: 28686653; PMCID: PMC5501561.
Jenkins FJ, Kerr CM, Fouquerel E, Bovbjerg DH, Opresko PL. Modified Terminal Restriction Fragment Analysis for Quantifying Telomere Length Using In-gel Hybridization. J Vis Exp. 2017 Jul 10;(125): doi: 10.3791/56001. PubMed PMID: 28715381; PMCID: PMC5612054.
Zhao J, Minami Y, Etling E, Coleman JM, Lauder SN, Tyrrell V, Aldrovandi M, O'Donnell V, Claesson HE, Kagan V, Wenzel S. Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2017 Dec;57(6):692-701. doi: 10.1165/rcmb.2017-0031OC. PubMed PMID: 28723225; PMCID: PMC5765418.
O'Donnell BM, Mackie TD, Brodsky JL. Linking chanelopathies with endoplasmic reticulum associated degradation. Channels (Austin). 2017 Nov 2;11(6):499-501. doi: 10.1080/19336950.2017.1357944. PubMed PMID: 28723237; PMCID: PMC5786258.
Tourkova IL, Liu L, Sutjarit N, Larrouture QC, Luo J, Robinson LJ, Blair HC. Adrenocorticotropic hormone and 1,25-dihydroxyvitamin D3 enhance human osteogenesis in vitro by synergistically accelerating the expression of bone-specific genes. Lab Invest. 2017 Sep;97(9):1072-1083. doi: 10.1038/labinvest.2017.62. PubMed PMID: 28737765; PMCID: PMC5844701.
Li Y, Li J, Wang Y, Zhang Y, Chu J, Sun C, Fu Z, Huang Y, Zhang H, Yuan H, Yin Y. Roles of cancer/testis antigens (CTAs) in breast cancer. Cancer Lett. 2017 Jul 28;39964-73. doi: 10.1016/j.canlet.2017.02.031. PubMed PMID: 28274891.
Zacchi LF, Dittmar JC, Mihalevic MJ, Shewan AM, Schulz BL, Brodsky JL, Bernstein KA. Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE. Dis Model Mech. 2017 Sep 1;10(9):1129-1140. doi: 10.1242/dmm.029926. PubMed PMID: 28768697; PMCID: PMC5611967.
Akiyama H, Ramirez NP, Gibson G, Kline C, Watkins S, Ambrose Z, Gummuluru S. Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon. J Virol. 2017 Nov 1;91(21): doi: 10.1128/JVI.00972-17. PubMed PMID: 28794041; PMCID: PMC5640826.
Xie Y, Zhu S, Song X, Sun X, Fan Y, Liu J, Zhong M, Yuan H, Zhang L, Billiar TR, Lotze MT, Zeh HJ 3rd, Kang R, Kroemer G, Tang D. The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. Cell Rep. 2017 Aug 15;20(7):1692-1704. doi: 10.1016/j.celrep.2017.07.055. PubMed PMID: 28813679.
Gleixner AM, Hutchison DF, Sannino S, Bhatia TN, Leak LC, Flaherty PT, Wipf P, Brodsky JL, Leak RK. N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione. Mol Pharmacol. 2017 Nov;92(5):564-575. doi: 10.1124/mol.117.109926. PubMed PMID: 28830914; PMCID: PMC5635514.
Tyurina YY, Shrivastava I, Tyurin VA, Mao G, Dar HH, Watkins S, Epperly M, Bahar I, Shvedova AA, Pitt B, Wenzel SE, Mallampalli RK, Sadovsky Y, Gabrilovich D, Greenberger JS, Bayır H, Kagan VE. "Only a Life Lived for Others Is Worth Living": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions. Antioxid Redox Signal. 2018 Nov 1;29(13):1333-1358. doi: 10.1089/ars.2017.7124. PubMed PMID: 28835115; PMCID: PMC6157439.
Helfield BL, Chen X, Qin B, Watkins SC, Villanueva FS. Mechanistic Insight into Sonoporation with Ultrasound-Stimulated Polymer Microbubbles. Ultrasound Med Biol. 2017 Nov;43(11):2678-2689. doi: 10.1016/j.ultrasmedbio.2017.07.017. PubMed PMID: 28847500; PMCID: PMC5644032.
Zhou J, Chan J, Lambelé M, Yusufzai T, Stumpff J, Opresko PL, Thali M, Wallace SS. NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis. Cell Rep. 2017 Aug 29;20(9):2044-2056. doi: 10.1016/j.celrep.2017.08.020. PubMed PMID: 28854357; PMCID: PMC5606162.
Yan G, Chen V, Lu X, Lu S. A signal-based method for finding driver modules of breast cancer metastasis to the lung. Sci Rep. 2017 Aug 30;7(1):10023. doi: 10.1038/s41598-017-09951-2. PubMed PMID: 28855549; PMCID: PMC5577160.
Boyiadzis M, Agha M, Redner RL, Sehgal A, Im A, Hou JZ, Farah R, Dorritie KA, Raptis A, Lim SH, Wang H, Lapteva N, Mei Z, Butterfield LH, Rooney CM, Whiteside TL. Phase 1 clinical trial of adoptive immunotherapy using "off-the-shelf" activated natural killer cells in patients with refractory and relapsed acute myeloid leukemia. Cytotherapy. 2017 Oct;19(10):1225-1232. doi: 10.1016/j.jcyt.2017.07.008. PubMed PMID: 28864289.
Van Oss SB, Cucinotta CE, Arndt KM. Emerging Insights into the Roles of the Paf1 Complex in Gene Regulation. Trends Biochem Sci. 2017 Oct;42(10):788-798. doi: 10.1016/j.tibs.2017.08.003. PubMed PMID: 28870425; PMCID: PMC5658044.
Kiesel BF, Scemama J, Parise RA, Villaruz L, Iffland A, Doyle A, Ivy P, Chu E, Bakkenist CJ, Beumer JH. LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma. J Pharm Biomed Anal. 2017 Nov 30;146244-250. doi: 10.1016/j.jpba.2017.08.037. PubMed PMID: 28888173; PMCID: PMC5632222.
Muller L, Simms P, Hong CS, Nishimura MI, Jackson EK, Watkins SC, Whiteside TL. Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms. Oncoimmunology. 2017;6(8):e1261243. doi: 10.1080/2162402X.2016.1261243. PubMed PMID: 28919985; PMCID: PMC5593709.
Beckwitt EC, Van Houten B. Molecular cartography of mutational landscapes in melanomas. EMBO J. 2017 Oct 2;36(19):2812-2814. doi: 10.15252/embj.201797944. PubMed PMID: 28931563; PMCID: PMC5623845.
Geric I, Tyurina YY, Krysko O, Krysko DV, De Schryver E, Kagan VE, Van Veldhoven PP, Baes M, Verheijden S. Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal β-oxidation deficiency. Immunology. 2018 Mar;153(3):342-356. doi: 10.1111/imm.12844. PubMed PMID: 28940384; PMCID: PMC5795189.
Eiseman JL, Sciullo M, Wang H, Beumer JH, Horn CC. Estimation of body surface area in the musk shrew ( Suncus murinus): a small animal for testing chemotherapy-induced emesis. Lab Anim. 2017 Oct;51(5):534-537. doi: 10.1177/0023677217695851. PubMed PMID: 28948895; PMCID: PMC5654602.
Tian L, Eldridge L, Chaudhari P, Zhang L, Anders RA, Schwarz KB, Ye Z, Jang YY. Derivation of a disease-specific human induced pluripotent stem cell line from a biliary atresia patient. Stem Cell Res. 2017 Oct;2425-28. doi: 10.1016/j.scr.2017.08.001. PubMed PMID: 29034890; PMCID: PMC5881114.
Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy RJ, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin K, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov. 2018 Jan;8(1):37-48. doi: 10.1158/2159-8290.CD-17-0395. PubMed PMID: 28978556; PMCID: PMC5894850.
Lee HT, Bose A, Lee CY, Opresko PL, Myong S. Molecular mechanisms by which oxidative DNA damage promotes telomerase activity. Nucleic Acids Res. 2017 Nov 16;45(20):11752-11765. doi: 10.1093/nar/gkx789. PubMed PMID: 28981887; PMCID: PMC5714237.
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. PubMed PMID: 28985560; PMCID: PMC5685180.
Varlakhanova NV, Mihalevic MJ, Bernstein KA, Ford MGJ. Pib2 and the EGO complex are both required for activation of TORC1. J Cell Sci. 2017 Nov 15;130(22):3878-3890. doi: 10.1242/jcs.207910. PubMed PMID: 28993463; PMCID: PMC5702048.
Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP. Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis. Hepatology. 2018 Jun;67(6):2320-2337. doi: 10.1002/hep.29585. PubMed PMID: 29023813; PMCID: PMC5893443.
Hernandez-Prera JC, Machado RA, Asa SL, Baloch Z, Faquin WC, Ghossein R, LiVolsi VA, Lloyd RV, Mete O, Nikiforov YE, Seethala RR, Suster S, Thompson LD, Turk AT, Sadow PM, Urken ML, Wenig BM. Pathologic Reporting of Tall-Cell Variant of Papillary Thyroid Cancer: Have We Reached a Consensus? Thyroid. 2017 Dec;27(12):1498-1504. doi: 10.1089/thy.2017.0280. PubMed PMID: 29020884.
Krysko O, Aaes TL, Kagan VE, D'Herde K, Bachert C, Leybaert L, Vandenabeele P, Krysko DV. Necroptotic cell death in anti-cancer therapy. Immunol Rev. 2017 Nov;280(1):207-219. doi: 10.1111/imr.12583. PubMed PMID: 29027225.
Schlattner U, Tokarska-Schlattner M, Epand RM, Boissan M, Lacombe ML, Kagan VE. NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy. Lab Invest. 2018 Feb;98(2):228-232. doi: 10.1038/labinvest.2017.113. PubMed PMID: 29035377.
Rudich P, Snoznik C, Watkins SC, Monaghan J, Pandey UB, Lamitina ST. Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans. Hum Mol Genet. 2017 Dec 15;26(24):4916-4928. doi: 10.1093/hmg/ddx372. PubMed PMID: 29036691; PMCID: PMC5886095.
Seethala RR, Baloch ZW, Barletta JA, Khanafshar E, Mete O, Sadow PM, LiVolsi VA, Nikiforov YE, Tallini G, Thompson LD. Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: a review for pathologists. Mod Pathol. 2018 Jan;31(1):39-55. doi: 10.1038/modpathol.2017.130. PubMed PMID: 29052599.
Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044. PubMed PMID: 29053969; PMCID: PMC5683852.
Hildreth AE, Arndt KM. A transcriptional switch controls meiosis. Elife. 2017 Oct 24;6 doi: 10.7554/eLife.31911. PubMed PMID: 29063829; PMCID: PMC5655149.
Washington MA, Balmert SC, Fedorchak MV, Little SR, Watkins SC, Meyer TY. Monomer sequence in PLGA microparticles: Effects on acidic microclimates and in vivo inflammatory response. Acta Biomater. 2018 Jan;65259-271. doi: 10.1016/j.actbio.2017.10.043. PubMed PMID: 29101019.
Duangkhae P, Erdos G, Ryman KD, Watkins SC, Falo LD Jr, Marques ETA Jr, Barratt-Boyes SM. Interplay between Keratinocytes and Myeloid Cells Drives Dengue Virus Spread in Human Skin. J Invest Dermatol. 2018 Mar;138(3):618-626. doi: 10.1016/j.jid.2017.10.018. PubMed PMID: 29106931.
Liu L, Kong M, Gassman NR, Freudenthal BD, Prasad R, Zhen S, Watkins SC, Wilson SH, Van Houten B. PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1. Nucleic Acids Res. 2017 Dec 15;45(22):12834-12847. doi: 10.1093/nar/gkx1047. PubMed PMID: 29121337; PMCID: PMC5728402.
Moiseeva T, Hood B, Schamus S, O'Connor MJ, Conrads TP, Bakkenist CJ. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nat Commun. 2017 Nov 9;8(1):1392. doi: 10.1038/s41467-017-01401-x. PubMed PMID: 29123096; PMCID: PMC5680267.
Uttam S, Liu Y. Fourier phase based depth-resolved nanoscale nuclear architecture mapping for cancer detection. Methods. 2018 Mar 1;136134-151. doi: 10.1016/j.ymeth.2017.10.011. PubMed PMID: 29127043; PMCID: PMC5857421.
Kaufman BA, Van Houten B. POLB: A new role of DNA polymerase beta in mitochondrial base excision repair. DNA Repair (Amst). 2017 Dec;60A1-A5. doi: 10.1016/j.dnarep.2017.11.002. PubMed PMID: 29129598; PMCID: PMC5713914.
Steinman J, Epperly M, Hou W, Willis J, Wang H, Fisher R, Liu B, Bahar I, McCaw T, Kagan V, Bayir H, Yu J, Wipf P, Li S, Huq MS, Greenberger JS. Improved Total-Body Irradiation Survival by Delivery of Two Radiation Mitigators that Target Distinct Cell Death Pathways. Radiat Res. 2018 Jan;189(1):68-83. doi: 10.1667/RR14787.1. PubMed PMID: 29140165; PMCID: PMC5808408.
Chen L, Vasilatos SN, Qin Y, Katz TA, Cao C, Wu H, Tasdemir N, Levine KM, Oesterreich S, Davidson NE, Huang Y. Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression. Oncotarget. 2017 Oct 10;8(47):81737-81753. doi: 10.18632/oncotarget.19387. PubMed PMID: 29137219; PMCID: PMC5669845.
Sannino S, Brodsky JL. Targeting protein quality control pathways in breast cancer. BMC Biol. 2017 Nov 16;15(1):109. doi: 10.1186/s12915-017-0449-4. PubMed PMID: 29145850; PMCID: PMC5689203.
Nakasone MA, Lewis TA, Walker O, Thakur A, Mansour W, Castañeda CA, Goeckeler-Fried JL, Parlati F, Chou TF, Hayat O, Zhang D, Camara CM, Bonn SM, Nowicka UK, Krueger S, Glickman MH, Brodsky JL, Deshaies RJ, Fushman D. Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway. Structure. 2017 Dec 5;25(12):1839-1855.e11. doi: 10.1016/j.str.2017.10.007. PubMed PMID: 29153505; PMCID: PMC5731780.
Woodcock CC, Huang Y, Woodcock SR, Salvatore SR, Singh B, Golin-Bisello F, Davidson NE, Neumann CA, Freeman BA, Wendell SG. Nitro-fatty acid inhibition of triple-negative breast cancer cell viability, migration, invasion, and tumor growth. J Biol Chem. 2018 Jan 26;293(4):1120-1137. doi: 10.1074/jbc.M117.814368. PubMed PMID: 29158255; PMCID: PMC5787792.
Van Houten B, Santa-Gonzalez GA, Camargo M. DNA repair after oxidative stress: current challenges. Curr Opin Toxicol. 2018 Feb;79-16. doi: 10.1016/j.cotox.2017.10.009. PubMed PMID: 29159324; PMCID: PMC5693256.
Efanov AA, Brenner AV, Bogdanova TI, Kelly LM, Liu P, Little MP, Wald AI, Hatch M, Zurnadzy LY, Nikiforova MN, Drozdovitch V, Leeman-Neill R, Mabuchi K, Tronko MD, Chanock SJ, Nikiforov YE. Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer. J Natl Cancer Inst. 2018 Apr 1;110(4):371-378. doi: 10.1093/jnci/djx209. PubMed PMID: 29165687; PMCID: PMC6059206.
Argani P, Kao YC, Zhang L, Bacchi C, Matoso A, Alaggio R, Epstein JI, Antonescu CR. Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues. Am J Surg Pathol. 2017 Dec;41(12):1702-1712. doi: 10.1097/PAS.0000000000000926. PubMed PMID: 28817404; PMCID: PMC5680139.
Schultz MA, Diaz AM, Smite S, Lay AR, DeCant B, McKinney R, Mascarinas WE, Xia Y, Neumann C, Bentrem D, Dawson DW, Grippo PJ. Thioredoxin system-mediated regulation of mutant Kras associated pancreatic neoplasia and cancer. Oncotarget. 2017 Nov 3;8(54):92667-92681. doi: 10.18632/oncotarget.21539. PubMed PMID: 29190947; PMCID: PMC5696213.
Geskin LJ, Akilov OE, Kwon S, Schowalter M, Watkins S, Whiteside TL, Butterfield LH, Falo LD Jr. Therapeutic reduction of cell-mediated immunosuppression in mycosis fungoides and Sézary syndrome. Cancer Immunol Immunother. 2018 Mar;67(3):423-434. doi: 10.1007/s00262-017-2090-z. PubMed PMID: 29204699.
Orenstein A, Berlyoung AS, Rastede EE, Pham HH, Fouquerel E, Murphy CT, Leibowitz BJ, Yu J, Srivastava T, Armitage BA, Opresko PL. γPNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue. Molecules. 2017 Dec 2;22(12): doi: 10.3390/molecules22122117. PubMed PMID: 29207465; PMCID: PMC5895088.
Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 2017 Dec 11;32(6):840-855.e8. doi: 10.1016/j.ccell.2017.11.005. PubMed PMID: 29232556; PMCID: PMC5734934.
Hampton MB, Vick KA, Skoko JJ, Neumann CA. Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer. Antioxid Redox Signal. 2018 Mar 1;28(7):591-608. doi: 10.1089/ars.2017.7422. PubMed PMID: 29237274.
Springall L, Hughes CD, Simons M, Azinas S, Van Houten B, Kad NM. Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival. Nucleic Acids Res. 2018 Feb 16;46(3):1256-1265. doi: 10.1093/nar/gkx1244. PubMed PMID: 29240933; PMCID: PMC5814901.
Liu B, Oltvai ZN, Bayır H, Silverman GA, Pak SC, Perlmutter DH, Bahar I. Quantitative assessment of cell fate decision between autophagy and apoptosis. Sci Rep. 2017 Dec 14;7(1):17605. doi: 10.1038/s41598-017-18001-w. PubMed PMID: 29242632; PMCID: PMC5730598.
Veglia F, Tyurin VA, Mohammadyani D, Blasi M, Duperret EK, Donthireddy L, Hashimoto A, Kapralov A, Amoscato A, Angelini R, Patel S, Alicea-Torres K, Weiner D, Murphy ME, Klein-Seetharaman J, Celis E, Kagan VE, Gabrilovich DI. Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer. Nat Commun. 2017 Dec 14;8(1):2122. doi: 10.1038/s41467-017-02186-9. PubMed PMID: 29242535; PMCID: PMC5730553.
Westmoreland JW, Mihalevic MJ, Bernstein KA, Resnick MA. The global role for Cdc13 and Yku70 in preventing telomere resection across the genome. DNA Repair (Amst). 2018 Feb;628-17. doi: 10.1016/j.dnarep.2017.11.010. PubMed PMID: 29247743; PMCID: PMC5989325.
Achkar T, Arjunan A, Wang H, Saul M, Davar D, Appleman LJ, Friedland D, Parikh RA. High-dose interleukin 2 in patients with metastatic renal cell carcinoma with sarcomatoid features. PLoS One. 2017;12(12):e0190084. doi: 10.1371/journal.pone.0190084. PubMed PMID: 29261796; PMCID: PMC5738119.
Pinilla-Macua I, Grassart A, Duvvuri U, Watkins SC, Sorkin A. EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo. Elife. 2017 Dec 21;6 doi: 10.7554/eLife.31993. PubMed PMID: 29268862; PMCID: PMC5741375.
Perkins LA, Yan Q, Schmidt BF, Kolodieznyi D, Saurabh S, Larsen MB, Watkins SC, Kremer L, Bruchez MP. Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking. Biochemistry. 2018 Feb 6;57(5):861-871. doi: 10.1021/acs.biochem.7b01135. PubMed PMID: 29283245.
Mohammadyani D, Yanamala N, Samhan-Arias AK, Kapralov AA, Stepanov G, Nuar N, Planas-Iglesias J, Sanghera N, Kagan VE, Klein-Seetharaman J. Structural characterization of cardiolipin-driven activation of cytochrome c into a peroxidase and membrane perturbation. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1057-1068. doi: 10.1016/j.bbamem.2018.01.009. PubMed PMID: 29317202.
Yuan JM, Beckman KB, Wang R, Bull C, Adams-Haduch J, Huang JY, Jin A, Opresko P, Newman AB, Zheng YL, Fenech M, Koh WP. Leukocyte telomere length in relation to risk of lung adenocarcinoma incidence: Findings from the Singapore Chinese Health Study. Int J Cancer. 2018 Jun 1;142(11):2234-2243. doi: 10.1002/ijc.31251. PubMed PMID: 29318605; PMCID: PMC5893405.
Mehta K, Im A, Rahman F, Wang H, Veldkamp P. Epidemiology and Outcomes of Hematopoietic Stem Cell Transplantation in Human Immunodeficiency Virus-Positive Patients From 1998 to 2012: A Nationwide Analysis. Clin Infect Dis. 2018 Jun 18;67(1):128-133. doi: 10.1093/cid/ciy010. PubMed PMID: 29325063.
He YM, Li X, Perego M, Nefedova Y, Kossenkov AV, Jensen EA, Kagan V, Liu YF, Fu SY, Ye QJ, Zhou YH, Wei L, Gabrilovich DI, Zhou J. Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation. Nat Med. 2018 Feb;24(2):224-231. doi: 10.1038/nm.4467. PubMed PMID: 29334374; PMCID: PMC5803434.
Lloyd RV, Asa SL, LiVolsi VA, Sadow PM, Tischler AS, Ghossein RA, Tuttle RM, Nikiforov YE. The evolving diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Hum Pathol. 2018 Apr;741-4. doi: 10.1016/j.humpath.2017.12.027. PubMed PMID: 29339178.
Nikiforova MN, Mercurio S, Wald AI, Barbi de Moura M, Callenberg K, Santana-Santos L, Gooding WE, Yip L, Ferris RL, Nikiforov YE. Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules. Cancer. 2018 Apr 15;124(8):1682-1690. doi: 10.1002/cncr.31245. PubMed PMID: 29345728; PMCID: PMC5891361.
Leipnitz G, Mohsen AW, Karunanidhi A, Seminotti B, Roginskaya VY, Markantone DM, Grings M, Mihalik SJ, Wipf P, Van Houten B, Vockley J. Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency. Sci Rep. 2018 Jan 18;8(1):1165. doi: 10.1038/s41598-018-19543-3. PubMed PMID: 29348607; PMCID: PMC5773529.
Huang Y, Yin Y, Sun M. Targeting LSD2 in breast cancer. Aging (Albany NY). 2018 Jan 20;10(1):11-12. doi: 10.18632/aging.101371. PubMed PMID: 29356682; PMCID: PMC5811254.
Bueno M, Brands J, Voltz L, Fiedler K, Mays B, St Croix C, Sembrat J, Mallampalli RK, Rojas M, Mora AL. ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. Aging Cell. 2018 Apr;17(2): doi: 10.1111/acel.12720. PubMed PMID: 29363258; PMCID: PMC5847866.
Wei L, Leibowitz BJ, Epperly M, Bi C, Li A, Steinman J, Wipf P, Li S, Zhang L, Greenberger J, Yu J. The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice. Sci Rep. 2018 Feb 1;8(1):2072. doi: 10.1038/s41598-018-20370-9. PubMed PMID: 29391546; PMCID: PMC5794877.
Fletcher R, Wang YJ, Schoen RE, Finn OJ, Yu J, Zhang L. Colorectal cancer prevention: Immune modulation taking the stage. Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):138-148. doi: 10.1016/j.bbcan.2017.12.002. PubMed PMID: 29391185; PMCID: PMC5955808.
Leibowitz BJ, Yang L, Wei L, Buchanan ME, Rachid M, Parise RA, Beumer JH, Eiseman JL, Schoen RE, Zhang L, Yu J. Targeting p53-dependent stem cell loss for intestinal chemoprotection. Sci Transl Med. 2018 Feb 7;10(427): doi: 10.1126/scitranslmed.aam7610. PubMed PMID: 29437148; PMCID: PMC5827930.
Ma J, Salamoun J, Wipf P, Edwards R, Van Houten B, Qian W. Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential. Oncotarget. 2018 Jan 19;9(5):6042-6054. doi: 10.18632/oncotarget.23679. PubMed PMID: 29464053; PMCID: PMC5814193.
Bo W, Schoedel KE, Carty SE, Radkay LA, Ohori NP, Nikiforov YE, Nikiforova MN, Yip L. Incidental Diagnosis of Parathyroid Lesions by Preoperative Use of Next-Generation Molecular Testing. World J Surg. 2018 Sep;42(9):2840-2845. doi: 10.1007/s00268-018-4548-3. PubMed PMID: 29470700.
Li X, Li M, Ruan H, Qiu W, Xu X, Lin Z, Yu J. Correction: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress. Oncotarget. 2018 Jan 23;9(6):7271. doi: 10.18632/oncotarget.24288. PubMed PMID: 29467964; PMCID: PMC5805550.
Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology. 2018 Jun;154(8):2060-2063.e8. doi: 10.1053/j.gastro.2018.02.026. PubMed PMID: 29486199; PMCID: PMC5985217.
Thompson LDR, Poller DN, Kakudo K, Burchette R, Nikiforov YE, Seethala RR. An International Interobserver Variability Reporting of the Nuclear Scoring Criteria to Diagnose Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: a Validation Study. Endocr Pathol. 2018 Sep;29(3):242-249. doi: 10.1007/s12022-018-9520-0. PubMed PMID: 29508145.
Menk AV, Scharping NE, Rivadeneira DB, Calderon MJ, Watson MJ, Dunstane D, Watkins SC, Delgoffe GM. 4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses. J Exp Med. 2018 Apr 2;215(4):1091-1100. doi: 10.1084/jem.20171068. PubMed PMID: 29511066; PMCID: PMC5881463.
Mon SY, Riedlinger G, Abbott CE, Seethala R, Ohori NP, Nikiforova MN, Nikiforov YE, Hodak SP. Cancer risk and clinicopathological characteristics of thyroid nodules harboring thyroid-stimulating hormone receptor gene mutations. Diagn Cytopathol. 2018 May;46(5):369-377. doi: 10.1002/dc.23915. PubMed PMID: 29516685.
Sadahiro H, Kang KD, Gibson JT, Minata M, Yu H, Shi J, Chhipa R, Chen Z, Lu S, Simoni Y, Furuta T, Sabit H, Zhang S, Bastola S, Yamaguchi S, Alsheikh H, Komarova S, Wang J, Kim SH, Hambardzumyan D, Lu X, Newell EW, DasGupta B, Nakada M, Lee LJ, Nabors B, Norian LA, Nakano I. Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma. Cancer Res. 2018 Jun 1;78(11):3002-3013. doi: 10.1158/0008-5472.CAN-17-2433. PubMed PMID: 29531161; PMCID: PMC5984695.
Luthra S, Chandran U, Diergaarde B, Becich M, Lee AV, Neumann CA. Expression of reactive species related genes is associated with patient survival in luminal B breast cancer. Free Radic Biol Med. 2018 May 20;120170-180. doi: 10.1016/j.freeradbiomed.2018.03.011. PubMed PMID: 29545070; PMCID: PMC5940524.
Sutera P, Bernard ME, Wang H, Bahary N, Burton S, Zeh H, Heron DE. Stereotactic Body Radiation Therapy for Locally Progressive and Recurrent Pancreatic Cancer after Prior Radiation. Front Oncol. 2018;852. doi: 10.3389/fonc.2018.00052. PubMed PMID: 29564223; PMCID: PMC5845878.
Evdokimova VN, Gandhi M, Nikitski AV, Bakkenist CJ, Nikiforov YE. Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements. Oncotarget. 2018 Mar 2;9(17):13612-13622. doi: 10.18632/oncotarget.24434. PubMed PMID: 29568381; PMCID: PMC5862602.
Willis J, Epperly MW, Fisher R, Zhang X, Shields D, Hou W, Wang H, Li S, Wipf P, Parmar K, Guinan E, Steinman J, Greenberger JS. Amelioration of Head and Neck Radiation-Induced Mucositis and Distant Marrow Suppression in Fanca-/- and Fancg-/- Mice by Intraoral Administration of GS-Nitroxide (JP4-039). Radiat Res. 2018 Jun;189(6):560-578. doi: 10.1667/RR14878.1. PubMed PMID: 29584588; PMCID: PMC5973476.
Chen D, Tong J, Yang L, Wei L, Stolz DB, Yu J, Zhang J, Zhang L. PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3930-3935. doi: 10.1073/pnas.1717190115. PubMed PMID: 29581256; PMCID: PMC5899441.
Gao Y, Tan J, Jin J, Ma H, Chen X, Leger B, Xu J, Spagnol ST, Dahl KN, Levine AS, Liu Y, Lan L. SIRT6 facilitates directional telomere movement upon oxidative damage. Sci Rep. 2018 Mar 29;8(1):5407. doi: 10.1038/s41598-018-23602-0. PubMed PMID: 29599436; PMCID: PMC5876328.
Barnes RP, Fouquerel E, Opresko PL. The impact of oxidative DNA damage and stress on telomere homeostasis. Mech Ageing Dev. 2019 Jan;17737-45. doi: 10.1016/j.mad.2018.03.013. PubMed PMID: 29604323; PMCID: PMC6162185.
Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. PubMed PMID: 29610484; PMCID: PMC5899674.
Cao C, Wu H, Vasilatos SN, Chandran U, Qin Y, Wan Y, Oesterreich S, Davidson NE, Huang Y. HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells. Int J Cancer. 2018 Sep 15;143(6):1388-1401. doi: 10.1002/ijc.31419. PubMed PMID: 29633255; PMCID: PMC6105499.
Ning J, Zhong Z, Fischer DK, Harris G, Watkins SC, Ambrose Z, Zhang P. Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid. J Virol. 2018 Jul 1;92(13): doi: 10.1128/JVI.00368-18. PubMed PMID: 29643241; PMCID: PMC6002704.
Watkins SC, St Croix CM. Light sheet imaging comes of age. J Cell Biol. 2018 May 7;217(5):1567-1569. doi: 10.1083/jcb.201804016. PubMed PMID: 29653995; PMCID: PMC5940317.
Choy CH, Saffi G, Gray MA, Wallace C, Dayam RM, Ou ZA, Lenk G, Puertollano R, Watkins SC, Botelho RJ. Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence. J Cell Sci. 2018 May 21;131(10): doi: 10.1242/jcs.213587. PubMed PMID: 29661845; PMCID: PMC6031331.
Kakudo K, El-Naggar AK, Hodak SP, Khanafshar E, Nikiforov YE, Nosé V, Thompson LDR. Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in thyroid tumor classification. Pathol Int. 2018 Jun;68(6):327-333. doi: 10.1111/pin.12673. PubMed PMID: 29675873.
Preston GM, Guerriero CJ, Metzger MB, Michaelis S, Brodsky JL. Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation. Mol Cell. 2018 Apr 19;70(2):242-253.e6. doi: 10.1016/j.molcel.2018.03.016. PubMed PMID: 29677492; PMCID: PMC5912696.
Sun Z, Brodsky JL. The degradation pathway of a model misfolded protein is determined by aggregation propensity. Mol Biol Cell. 2018 Jun 15;29(12):1422-1434. doi: 10.1091/mbc.E18-02-0117. PubMed PMID: 29688814; PMCID: PMC6014095.
Li Y, Chu J, Li J, Feng W, Yang F, Wang Y, Zhang Y, Sun C, Yang M, Vasilatos SN, Huang Y, Fu Z, Yin Y. Cancer/testis antigen-Plac1 promotes invasion and metastasis of breast cancer through Furin/NICD/PTEN signaling pathway. Mol Oncol. 2018 Aug;12(8):1233-1248. doi: 10.1002/1878-0261.12311. PubMed PMID: 29704427; PMCID: PMC6068355.
Kao YC, Owosho AA, Sung YS, Zhang L, Fujisawa Y, Lee JC, Wexler L, Argani P, Swanson D, Dickson BC, Fletcher CDM, Antonescu CR. BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas. Am J Surg Pathol. 2018 May;42(5):604-615. doi: 10.1097/PAS.0000000000000965. PubMed PMID: 29300189; PMCID: PMC5893395.
Du T, Zhu L, Levine KM, Tasdemir N, Lee AV, Vignali DAA, Houten BV, Tseng GC, Oesterreich S. Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism. Sci Rep. 2018 May 8;8(1):7205. doi: 10.1038/s41598-018-25357-0. PubMed PMID: 29739984; PMCID: PMC5940770.
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ. Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biol. 2018 Jul;17259-273. doi: 10.1016/j.redox.2018.04.007. PubMed PMID: 29747066; PMCID: PMC6006678.
Knickelbein K, Tong J, Chen D, Wang YJ, Misale S, Bardelli A, Yu J, Zhang L. Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer. Oncogene. 2018 Aug;37(33):4599-4610. doi: 10.1038/s41388-018-0289-x. PubMed PMID: 29755130; PMCID: PMC6195818.
Kumar D, New J, Vishwakarma V, Joshi R, Enders J, Lin F, Dasari S, Gutierrez WR, Leef G, Ponnurangam S, Chavan H, Ganaden L, Thornton MM, Dai H, Tawfik O, Straub J, Shnayder Y, Kakarala K, Tsue TT, Girod DA, Van Houten B, Anant S, Krishnamurthy P, Thomas SM. Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression. Cancer Res. 2018 Jul 15;78(14):3769-3782. doi: 10.1158/0008-5472.CAN-17-1076. PubMed PMID: 29769197; PMCID: PMC6050074.
Hager NA, Krasowski CJ, Mackie TD, Kolb AR, Needham PG, Augustine AA, Dempsey A, Szent-Gyorgyi C, Bruchez MP, Bain DJ, Kwiatkowski AV, O'Donnell AF, Brodsky JL. Select α-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. J Biol Chem. 2018 Jul 13;293(28):11006-11021. doi: 10.1074/jbc.RA117.001293. PubMed PMID: 29784874; PMCID: PMC6052216.
Alves VAF, Kakudo K, LiVolsi V, Lloyd RV, Nikiforov YE, Nosé V, Papotti M, Thompson LDR. Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features (NIFTP): Achieving Better Agreement By Refining Diagnostic Criteria. Clinics (Sao Paulo). 2018 May 21;73e576. doi: 10.6061/clinics/2018/e576. PubMed PMID: 29791602; PMCID: PMC5952051.
Joshi S, Wang T, Araujo TLS, Sharma S, Brodsky JL, Chiosis G. Adapting to stress - chaperome networks in cancer. Nat Rev Cancer. 2018 Sep;18(9):562-575. doi: 10.1038/s41568-018-0020-9. PubMed PMID: 29795326; PMCID: PMC6108944.
Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR. Regulation of lipid peroxidation and ferroptosis in diverse species. Genes Dev. 2018 May 1;32(9-10):602-619. doi: 10.1101/gad.314674.118. PubMed PMID: 29802123; PMCID: PMC6004068.
Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 2018 May 29;7 doi: 10.7554/eLife.37018. PubMed PMID: 29809151; PMCID: PMC5995541.
Zhang J, Tian XJ, Chen YJ, Wang W, Watkins S, Xing J. Pathway crosstalk enables cells to interpret TGF-β duration. NPJ Syst Biol Appl. 2018;418. doi: 10.1038/s41540-018-0060-5. PubMed PMID: 29872541; PMCID: PMC5972147.
Zhao J, Zhang L, Mu X, Doebelin C, Nguyen W, Wallace C, Reay DP, McGowan SJ, Corbo L, Clemens PR, Wilson GM, Watkins SC, Solt LA, Cameron MD, Huard J, Niedernhofer LJ, Kamenecka TM, Robbins PD. Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation. PLoS Biol. 2018 Jun;16(6):e2004663. doi: 10.1371/journal.pbio.2004663. PubMed PMID: 29889904; PMCID: PMC6013238.
Tong J, Zheng X, Tan X, Fletcher R, Nikolovska-Coleska Z, Yu J, Zhang L. Mcl-1 Phosphorylation without Degradation Mediates Sensitivity to HDAC Inhibitors by Liberating BH3-Only Proteins. Cancer Res. 2018 Aug 15;78(16):4704-4715. doi: 10.1158/0008-5472.CAN-18-0399. PubMed PMID: 29895675; PMCID: PMC6298746.
Nikiforov YE, Baloch ZW, Hodak SP, Giordano TJ, Lloyd RV, Seethala RR, Wenig BM. Change in Diagnostic Criteria for Noninvasive Follicular Thyroid Neoplasm With Papillarylike Nuclear Features. JAMA Oncol. 2018 Aug 1;4(8):1125-1126. doi: 10.1001/jamaoncol.2018.1446. PubMed PMID: 29902314; PMCID: PMC6584712.
Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga SP. Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma. Am J Pathol. 2018 Aug;188(8):1895-1909. doi: 10.1016/j.ajpath.2018.05.006. PubMed PMID: 29920228; PMCID: PMC6099390.
Pangeni RP, Zhang Z, Alvarez AA, Wan X, Sastry N, Lu S, Shi T, Huang T, Lei CX, James CD, Kessler JA, Brennan CW, Nakano I, Lu X, Hu B, Zhang W, Cheng SY. Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma. Epigenetics. 2018;13(4):432-448. doi: 10.1080/15592294.2018.1469892. PubMed PMID: 29927689; PMCID: PMC6140806.
Lou W, Ting HC, Reynolds CA, Tyurina YY, Tyurin VA, Li Y, Ji J, Yu W, Liang Z, Stoyanovsky DA, Anthonymuthu TS, Frasso MA, Wipf P, Greenberger JS, Bayır H, Kagan VE, Greenberg ML. Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1354-1368. doi: 10.1016/j.bbalip.2018.06.016. PubMed PMID: 29935382; PMCID: PMC6641546.
Callenberg KM, Santana-Santos L, Chen L, Ernst WL, De Moura MB, Nikiforov YE, Nikiforova MN, Roy S. Clinical Implementation and Validation of Automated Human Genome Variation Society (HGVS) Nomenclature System for Next-Generation Sequencing-Based Assays for Cancer. J Mol Diagn. 2018 Sep;20(5):628-634. doi: 10.1016/j.jmoldx.2018.05.006. PubMed PMID: 29936258.
Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T. Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma. J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. PubMed PMID: 29939160; PMCID: PMC6063467.
Ferris RL, Nikiforov Y, Terris D, Seethala RR, Ridge JA, Angelos P, Duh QY, Wong R, Sabra MM, Fagin JA, McIver B, Bernet VJ, Harrell RM, Busaidy N, Cibas ES, Faquin WC, Sadow P, Baloch Z, Shindo M, Orloff L, Davies L, Randolph GW. AHNS Series: Do you know your guidelines? AHNS Endocrine Section Consensus Statement: State-of-the-art thyroid surgical recommendations in the era of noninvasive follicular thyroid neoplasm with papillary-like nuclear features. Head Neck. 2018 Sep;40(9):1881-1888. doi: 10.1002/hed.25141. PubMed PMID: 29947030; PMCID: PMC6175359.
Van Houten B, Kad NM. Single-cell mutagenic responses and cell death revealed in real time. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7168-7170. doi: 10.1073/pnas.1808986115. PubMed PMID: 29946022; PMCID: PMC6048557.
Vendetti FP, Karukonda P, Clump DA, Teo T, Lalonde R, Nugent K, Ballew M, Kiesel BF, Beumer JH, Sarkar SN, Conrads TP, O'Connor MJ, Ferris RL, Tran PT, Delgoffe GM, Bakkenist CJ. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. J Clin Invest. 2018 Aug 31;128(9):3926-3940. doi: 10.1172/JCI96519. PubMed PMID: 29952768; PMCID: PMC6118586.
Pradhan-Sundd T, Vats R, Russell JO, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P. Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice. Gastroenterology. 2018 Oct;155(4):1218-1232.e24. doi: 10.1053/j.gastro.2018.06.048. PubMed PMID: 29964040; PMCID: PMC6174089.
Lontos K, Adamik J, Tsagianni A, Galson DL, Chirgwin JM, Suvannasankha A. The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis. Front Endocrinol (Lausanne). 2018;9322. doi: 10.3389/fendo.2018.00322. PubMed PMID: 29971044; PMCID: PMC6018527.
Adamik J, Silbermann R, Marino S, Sun Q, Anderson JL, Zhou D, Xie XQ, Roodman GD, Galson DL. XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression. Front Endocrinol (Lausanne). 2018;9344. doi: 10.3389/fendo.2018.00344. PubMed PMID: 30008697; PMCID: PMC6033965.
Chu J, Li Y, Fan X, Ma J, Li J, Lu G, Zhang Y, Huang Y, Li W, Huang X, Fu Z, Yin Y, Yuan H. MiR-4319 Suppress the Malignancy of Triple-Negative Breast Cancer by Regulating Self-Renewal and Tumorigenesis of Stem Cells. Cell Physiol Biochem. 2018;48(2):593-604. doi: 10.1159/000491888. PubMed PMID: 30021199.
Caves EA, Cook SA, Lee N, Stoltz D, Watkins S, Shair KHY. Air-Liquid Interface Method To Study Epstein-Barr Virus Pathogenesis in Nasopharyngeal Epithelial Cells. mSphere. 2018 Jul 18;3(4): doi: 10.1128/mSphere.00152-18. PubMed PMID: 30021875; PMCID: PMC6052337.
Van Laar VS, Arnold B, Howlett EH, Calderon MJ, St Croix CM, Greenamyre JT, Sanders LH, Berman SB. Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress. J Neurosci. 2018 Aug 22;38(34):7505-7515. doi: 10.1523/JNEUROSCI.0541-18.2018. PubMed PMID: 30030401; PMCID: PMC6104298.
Xu J, Ma H, Jin J, Uttam S, Fu R, Huang Y, Liu Y. Super-Resolution Imaging of Higher-Order Chromatin Structures at Different Epigenomic States in Single Mammalian Cells. Cell Rep. 2018 Jul 24;24(4):873-882. doi: 10.1016/j.celrep.2018.06.085. PubMed PMID: 30044984; PMCID: PMC6154382.
Fourcade J, Sun Z, Chauvin JM, Ka M, Davar D, Pagliano O, Wang H, Saada S, Menna C, Amin R, Sander C, Kirkwood JM, Korman AJ, Zarour HM. CD226 opposes TIGIT to disrupt Tregs in melanoma. JCI Insight. 2018 Jul 26;3(14): doi: 10.1172/jci.insight.121157. PubMed PMID: 30046006; PMCID: PMC6124410.
Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, Lin R, Maier TJ, Goldbach-Mansky R, Miner CA, Qian W, Miner JJ, Rigby RE, Rehwinkel J, Jakobsen MR, Arai H, Taguchi T, Schopfer FJ, Olagnier D, Holm CK. Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7768-E7775. doi: 10.1073/pnas.1806239115. PubMed PMID: 30061387; PMCID: PMC6099880.
Gomes-Lima CJ, Nikiforov YE, Lee W, Burman KD. Synchronous Independent Papillary Thyroid Carcinomas in Struma Ovarii and the Thyroid Gland With Different RAS Mutations. J Endocr Soc. 2018 Aug 1;2(8):944-948. doi: 10.1210/js.2018-00132. PubMed PMID: 30087949; PMCID: PMC6065485.
Sutera PA, Bernard ME, Wang H, Heron DE. Prognostic Factors for Elderly Patients Treated With Stereotactic Body Radiation Therapy for Pancreatic Adenocarcinoma. Front Oncol. 2018;8282. doi: 10.3389/fonc.2018.00282. PubMed PMID: 30101127; PMCID: PMC6072866.
Ganly I, Makarov V, Deraje S, Dong Y, Reznik E, Seshan V, Nanjangud G, Eng S, Bose P, Kuo F, Morris LGT, Landa I, Carrillo Albornoz PB, Riaz N, Nikiforov YE, Patel K, Umbricht C, Zeiger M, Kebebew E, Sherman E, Ghossein R, Fagin JA, Chan TA. Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes. Cancer Cell. 2018 Aug 13;34(2):256-270.e5. doi: 10.1016/j.ccell.2018.07.002. PubMed PMID: 30107176; PMCID: PMC6247912.
Pearlstein S, Lahouti AH, Opher E, Nikiforov YE, Kuriloff DB. Thyroseq V3 Molecular Profiling for Tailoring the Surgical Management of Hürthle Cell Neoplasms. Case Rep Endocrinol. 2018;20189329035. doi: 10.1155/2018/9329035. PubMed PMID: 30105107; PMCID: PMC6076910.
Qin Y, Vasilatos SN, Chen L, Wu H, Cao Z, Fu Y, Huang M, Vlad AM, Lu B, Oesterreich S, Davidson NE, Huang Y. Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade. Oncogene. 2019 Jan;38(3):390-405. doi: 10.1038/s41388-018-0451-5. PubMed PMID: 30111819; PMCID: PMC6336685.
Nikitski AV, Rominski SL, Wankhede M, Kelly LM, Panebianco F, Barila G, Altschuler DL, Nikiforov YE. Mouse Model of Poorly Differentiated Thyroid Carcinoma Driven by STRN-ALK Fusion. Am J Pathol. 2018 Nov;188(11):2653-2661. doi: 10.1016/j.ajpath.2018.07.012. PubMed PMID: 30125543; PMCID: PMC6222272.
Tantikanlayaporn D, Tourkova IL, Larrouture Q, Luo J, Piyachaturawat P, Witt MR, Blair HC, Robinson LJ. Sphingosine-1-Phosphate Modulates the Effect of Estrogen in Human Osteoblasts. JBMR Plus. 2018 Jul;2(4):217-226. doi: 10.1002/jbm4.10037. PubMed PMID: 30123862; PMCID: PMC6095197.
Sannino S, Guerriero CJ, Sabnis AJ, Stolz DB, Wallace CT, Wipf P, Watkins SC, Bivona TG, Brodsky JL. Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells. J Cell Sci. 2018 Sep 5;131(17): doi: 10.1242/jcs.217760. PubMed PMID: 30131440; PMCID: PMC6140321.
Saydmohammed M, Yagi H, Calderon M, Clark MJ, Feinstein T, Sun M, Stolz DB, Watkins SC, Amack JD, Lo CW, Tsang M. Vertebrate myosin 1d regulates left-right organizer morphogenesis and laterality. Nat Commun. 2018 Aug 23;9(1):3381. doi: 10.1038/s41467-018-05866-2. PubMed PMID: 30139971; PMCID: PMC6107537.
Sutera P, Clump DA, Kalash R, D'Ambrosio D, Mihai A, Wang H, Petro DP, Burton SA, Heron DE. Initial Results of a Multicenter Phase 2 Trial of Stereotactic Ablative Radiation Therapy for Oligometastatic Cancer. Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):116-122. doi: 10.1016/j.ijrobp.2018.08.027. PubMed PMID: 30149056.
Lee YS, Lee DH, Jeong SY, Park SH, Oh SC, Park YS, Yu J, Choudry HA, Bartlett DL, Lee YJ. Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5. J Cell Biochem. 2019 Jan;120(1):928-939. doi: 10.1002/jcb.27456. PubMed PMID: 30160785; PMCID: PMC6249082.
Krainz T, Lamade AM, Du L, Maskrey TS, Calderon MJ, Watkins SC, Epperly MW, Greenberger JS, Bayır H, Wipf P, Clark RSB. Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor. ACS Chem Biol. 2018 Oct 19;13(10):2868-2879. doi: 10.1021/acschembio.8b00423. PubMed PMID: 30184433; PMCID: PMC6402482.
Du T, Sikora MJ, Levine KM, Tasdemir N, Riggins RB, Wendell SG, Van Houten B, Oesterreich S. Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer. Breast Cancer Res. 2018 Sep 4;20(1):106. doi: 10.1186/s13058-018-1041-8. PubMed PMID: 30180878; PMCID: PMC6124012.
Lu S, Fan X, Chen L, Lu X. A novel method of using Deep Belief Networks and genetic perturbation data to search for yeast signaling pathways. PLoS One. 2018;13(9):e0203871. doi: 10.1371/journal.pone.0203871. PubMed PMID: 30208101; PMCID: PMC6135403.
Burkert SC, Shurin GV, White DL, He X, Kapralov AA, Kagan VE, Shurin MR, Star A. Targeting myeloid regulators by paclitaxel-loaded enzymatically degradable nanocups. Nanoscale. 2018 Sep 27;10(37):17990-18000. doi: 10.1039/c8nr04437f. PubMed PMID: 30226240; PMCID: PMC6563927.
Zhang J, Zhang S, Liu Y, Su M, Ling X, Liu F, Ge Y, Bai M. Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer. Photodiagnosis Photodyn Ther. 2018 Dec;24185-191. doi: 10.1016/j.pdpdt.2018.09.006. PubMed PMID: 30240926; PMCID: PMC6289793.
Moiseeva TN, Bakkenist CJ. Regulation of the initiation of DNA replication in human cells. DNA Repair (Amst). 2018 Dec;7299-106. doi: 10.1016/j.dnarep.2018.09.003. PubMed PMID: 30266203; PMCID: PMC6261693.
Petrusca DN, Toscani D, Wang FM, Park C, Crean CD, Anderson JL, Marino S, Mohammad KS, Zhou D, Silbermann R, Sun Q, Kurihara N, Galson DL, Giuliani N, Roodman GD. Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis. J Hematol Oncol. 2018 Oct 4;11(1):123. doi: 10.1186/s13045-018-0666-5. PubMed PMID: 30286780; PMCID: PMC6172782.
Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 2018 Nov;111373-381. doi: 10.1016/j.cyto.2018.10.001. PubMed PMID: 30300855; PMCID: PMC6364691.
Teng Y, Yadav T, Duan M, Tan J, Xiang Y, Gao B, Xu J, Liang Z, Liu Y, Nakajima S, Shi Y, Levine AS, Zou L, Lan L. ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB. Nat Commun. 2018 Oct 8;9(1):4115. doi: 10.1038/s41467-018-06586-3. PubMed PMID: 30297739; PMCID: PMC6175878.
Deng M, Tang Y, Li W, Wang X, Zhang R, Zhang X, Zhao X, Liu J, Tang C, Liu Z, Huang Y, Peng H, Xiao L, Tang D, Scott MJ, Wang Q, Liu J, Xiao X, Watkins S, Li J, Yang H, Wang H, Chen F, Tracey KJ, Billiar TR, Lu B. The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis. Immunity. 2018 Oct 16;49(4):740-753.e7. doi: 10.1016/j.immuni.2018.08.016. PubMed PMID: 30314759; PMCID: PMC6300139.
Bakkenist CJ, Lee JJ, Schmitz JC. ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer. Clin Colorectal Cancer. 2018 Dec;17(4):255-257. doi: 10.1016/j.clcc.2018.09.001. PubMed PMID: 30316683; PMCID: PMC6561466.
Wang YJ, Fletcher R, Yu J, Zhang L. Immunogenic effects of chemotherapy-induced tumor cell death. Genes Dis. 2018 Sep;5(3):194-203. doi: 10.1016/j.gendis.2018.05.003. PubMed PMID: 30320184; PMCID: PMC6176216.
Ling X, Zhang S, Liu Y, Bai M. Light-activatable cannabinoid prodrug for combined and target-specific photodynamic and cannabinoid therapy. J Biomed Opt. 2018 Oct;23(10):1-9. doi: 10.1117/1.JBO.23.10.108001. PubMed PMID: 30334393.
Yang F, Wang F, Liu Y, Wang S, Li X, Huang Y, Xia Y, Cao C. Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells. Life Sci. 2018 Nov 15;213149-157. doi: 10.1016/j.lfs.2018.10.034. PubMed PMID: 30352240.
Pulugulla SH, Workman R, Rutter NW, Yang Z, Adamik J, Lupish B, Macar DA, El Abdouni S, Esposito EX, Galson DL, Camacho CJ, Madura JD, Auron PE. A combined computational and experimental approach reveals the structure of a C/EBPβ-Spi1 interaction required for IL1B gene transcription. J Biol Chem. 2018 Dec 28;293(52):19942-19956. doi: 10.1074/jbc.RA118.005627. PubMed PMID: 30355733; PMCID: PMC6311527.
Davar D, Wang H, Chauvin JM, Pagliano O, Fourcade JJ, Ka M, Menna C, Rose A, Sander C, Borhani AA, Karunamurthy A, Tarhini AA, Tawbi HA, Zhao Q, Moreno BH, Ebbinghaus S, Ibrahim N, Kirkwood JM, Zarour HM. Phase Ib/II Study of Pembrolizumab and Pegylated-Interferon Alfa-2b in Advanced Melanoma. J Clin Oncol. 2018 Oct 25;JCO1800632. doi: 10.1200/JCO.18.00632. PubMed PMID: 30359157; PMCID: PMC6286160.
Clump DA, Pickering CR, Skinner HD. Predicting Outcome in Head and Neck Cancer: miRNAs with Potentially Big Effects. Clin Cancer Res. 2019 Mar 1;25(5):1441-1442. doi: 10.1158/1078-0432.CCR-18-3078. PubMed PMID: 30413524; PMCID: PMC6415532.
D'Aiuto L, McNulty J, Hartline C, Demers M, Kalkeri R, Wood J, McClain L, Chattopadhyay A, Zhi Y, Naciri J, Smith A, Yolken R, Chowdari K, Zepeda-Velazquez C, Dokuburra CB, Marques E, Ptak R, Kinchington P, Watkins S, Prichard M, Bloom D, Nimgaonkar V. R430: A potent inhibitor of DNA and RNA viruses. Sci Rep. 2018 Nov 9;8(1):16662. doi: 10.1038/s41598-018-33904-y. PubMed PMID: 30413769; PMCID: PMC6226428.
Steward DL, Carty SE, Sippel RS, Yang SP, Sosa JA, Sipos JA, Figge JJ, Mandel S, Haugen BR, Burman KD, Baloch ZW, Lloyd RV, Seethala RR, Gooding WE, Chiosea SI, Gomes-Lima C, Ferris RL, Folek JM, Khawaja RA, Kundra P, Loh KS, Marshall CB, Mayson S, McCoy KL, Nga ME, Ngiam KY, Nikiforova MN, Poehls JL, Ringel MD, Yang H, Yip L, Nikiforov YE. Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology: A Prospective Blinded Multicenter Study. JAMA Oncol. 2019 Feb 1;5(2):204-212. doi: 10.1001/jamaoncol.2018.4616. PubMed PMID: 30419129; PMCID: PMC6439562.
Seminotti B, Leipnitz G, Karunanidhi A, Kochersperger C, Roginskaya VY, Basu S, Wang Y, Wipf P, Van Houten B, Mohsen AW, Vockley J. Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers. Hum Mol Genet. 2019 Mar 15;28(6):928-941. doi: 10.1093/hmg/ddy403. PubMed PMID: 30445591; PMCID: PMC6400046.
Cheikhi A, Wallace C, St Croix C, Cohen C, Tang WY, Wipf P, Benos PV, Ambrosio F, Barchowsky A. Mitochondria are a substrate of cellular memory. Free Radic Biol Med. 2019 Jan;130528-541. doi: 10.1016/j.freeradbiomed.2018.11.028. PubMed PMID: 30472365.
Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA. Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells. J Biol Chem. 2019 Jan 11;294(2):397-404. doi: 10.1074/jbc.AC118.005899. PubMed PMID: 30478172; PMCID: PMC6333886.
Kenny EM, Fidan E, Yang Q, Anthonymuthu TS, New LA, Meyer EA, Wang H, Kochanek PM, Dixon CE, Kagan VE, Bayir H. Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury. Crit Care Med. 2019 Mar;47(3):410-418. doi: 10.1097/CCM.0000000000003555. PubMed PMID: 30531185; PMCID: PMC6449247.
Pabon NA, Xia Y, Estabrooks SK, Ye Z, Herbrand AK, Süß E, Biondi RM, Assimon VA, Gestwicki JE, Brodsky JL, Camacho CJ, Bar-Joseph Z. Predicting protein targets for drug-like compounds using transcriptomics. PLoS Comput Biol. 2018 Dec;14(12):e1006651. doi: 10.1371/journal.pcbi.1006651. PubMed PMID: 30532261; PMCID: PMC6300300.
Chiang AN, Liang M, Dominguez-Meijide A, Masaracchia C, Goeckeler-Fried JL, Mazzone CS, Newhouse DW, Kendsersky NM, Yates ME, Manos-Turvey A, Needham PG, Outeiro TF, Wipf P, Brodsky JL. Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorg Med Chem. 2019 Jan 1;27(1):79-91. doi: 10.1016/j.bmc.2018.11.011. PubMed PMID: 30528127; PMCID: PMC6298824.
Anthonymuthu TS, Kenny EM, Shrivastava I, Tyurina YY, Hier ZE, Ting HC, Dar HH, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Zhao J, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayır H. Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE. J Am Chem Soc. 2018 Dec 26;140(51):17835-17839. doi: 10.1021/jacs.8b09913. PubMed PMID: 30525572; PMCID: PMC6622169.
Ackermann S, Cartolano M, Hero B, Welte A, Kahlert Y, Roderwieser A, Bartenhagen C, Walter E, Gecht J, Kerschke L, Volland R, Menon R, Heuckmann JM, Gartlgruber M, Hartlieb S, Henrich KO, Okonechnikov K, Altmüller J, Nürnberg P, Lefever S, de Wilde B, Sand F, Ikram F, Rosswog C, Fischer J, Theissen J, Hertwig F, Singhi AD, Simon T, Vogel W, Perner S, Krug B, Schmidt M, Rahmann S, Achter V, Lang U, Vokuhl C, Ortmann M, Büttner R, Eggert A, Speleman F, O'Sullivan RJ, Thomas RK, Berthold F, Vandesompele J, Schramm A, Westermann F, Schulte JH, Peifer M, Fischer M. A mechanistic classification of clinical phenotypes in neuroblastoma. Science. 2018 Dec 7;362(6419):1165-1170. doi: 10.1126/science.aat6768. PubMed PMID: 30523111.
Sullivan MR, Bernstein KA. RAD-ical New Insights into RAD51 Regulation. Genes (Basel). 2018 Dec 13;9(12): doi: 10.3390/genes9120629. PubMed PMID: 30551670; PMCID: PMC6316741.
Chen D, Ni HM, Wang L, Ma X, Yu J, Ding WX, Zhang L. p53 Up-regulated Modulator of Apoptosis Induction Mediates Acetaminophen-Induced Necrosis and Liver Injury in Mice. Hepatology. 2019 May;69(5):2164-2179. doi: 10.1002/hep.30422. PubMed PMID: 30552702; PMCID: PMC6461480.
Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S. Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA. Nat Commun. 2018 Dec 17;9(1):5351. doi: 10.1038/s41467-018-07798-3. PubMed PMID: 30559436; PMCID: PMC6297235.
Ohori NP, Landau MS, Carty SE, Yip L, LeBeau SO, Manroa P, Seethala RR, Schoedel KE, Nikiforova MN, Nikiforov YE. Benign call rate and molecular test result distribution of ThyroSeq v3. Cancer Cytopathol. 2019 Mar;127(3):161-168. doi: 10.1002/cncy.22088. PubMed PMID: 30561907.
Baranov SV, Baranova OV, Yablonska S, Suofu Y, Vazquez AL, Kozai TDY, Cui XT, Ferrando LM, Larkin TM, Tyurina YY, Kagan VE, Carlisle DL, Kristal BS, Friedlander RM. Mitochondria modulate programmed neuritic retraction. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):650-659. doi: 10.1073/pnas.1811021116. PubMed PMID: 30584104; PMCID: PMC6329959.
Surve SV, Myers PJ, Clayton SA, Watkins SC, Lazzara MJ, Sorkin A. Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells. Mol Biol Cell. 2019 Feb 15;30(4):506-523. doi: 10.1091/mbc.E18-08-0512. PubMed PMID: 30586319; PMCID: PMC6594441.
Adamik J, Galson DL, Roodman GD. Osteoblast suppression in multiple myeloma bone disease. J Bone Oncol. 2018 Nov;1362-70. doi: 10.1016/j.jbo.2018.09.001. PubMed PMID: 30591859; PMCID: PMC6303385.
Li Y, Chu J, Feng W, Yang M, Zhang Y, Zhang Y, Qin Y, Xu J, Li J, Vasilatos SN, Fu Z, Huang Y, Yin Y. EPHA5 mediates trastuzumab resistance in HER2-positive breast cancers through regulating cancer stem cell-like properties. FASEB J. 2019 Apr;33(4):4851-4865. doi: 10.1096/fj.201701561RRRR. PubMed PMID: 30620624.
Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, Li Z, Bao Z, Chen H, You Y, Kochanek PM, Yin H, Liu N, Kagan VE, Bayır H, Ji J. Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury. J Neurosci. 2019 Mar 6;39(10):1930-1943. doi: 10.1523/JNEUROSCI.3415-17.2018. PubMed PMID: 30626699; PMCID: PMC6407296.
Ghosh A, Shao L, Sampath P, Zhao B, Patel NV, Zhu J, Behl B, Parise RA, Beumer JH, O'Sullivan RJ, DeLuca NA, Thorne SH, Rathinam VAK, Li P, Sarkar SN. Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production. Immunity. 2019 Jan 15;50(1):51-63.e5. doi: 10.1016/j.immuni.2018.12.013. PubMed PMID: 30635239; PMCID: PMC6342484.
Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nat Commun. 2019 Jan 11;10(1):175. doi: 10.1038/s41467-018-08073-1. PubMed PMID: 30635586; PMCID: PMC6329807.
Nikiforova MN, Nikitski AV, Panebianco F, Kaya C, Yip L, Williams M, Chiosea SI, Seethala RR, Roy S, Condello V, Santana-Santos L, Wald AI, Carty SE, Ferris RL, El-Naggar AK, Nikiforov YE. GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland. Thyroid. 2019 Feb;29(2):161-173. doi: 10.1089/thy.2018.0791. PubMed PMID: 30648929; PMCID: PMC6389773.
Capello M, Vykoukal JV, Katayama H, Bantis LE, Wang H, Kundnani DL, Aguilar-Bonavides C, Aguilar M, Tripathi SC, Dhillon DS, Momin AA, Peters H, Katz MH, Alvarez H, Bernard V, Ferri-Borgogno S, Brand R, Adler DG, Firpo MA, Mulvihill SJ, Molldrem JJ, Feng Z, Taguchi A, Maitra A, Hanash SM. Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. Nat Commun. 2019 Jan 16;10(1):254. doi: 10.1038/s41467-018-08109-6. PubMed PMID: 30651550; PMCID: PMC6335434.
Klein HL, Ang KKH, Arkin MR, Beckwitt EC, Chang YH, Fan J, Kwon Y, Morten MJ, Mukherjee S, Pambos OJ, El Sayyed H, Thrall ES, Vieira-da-Rocha JP, Wang Q, Wang S, Yeh HY, Biteen JS, Chi P, Heyer WD, Kapanidis AN, Loparo JJ, Strick TR, Sung P, Van Houten B, Niu H, Rothenberg E. Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes. Microb Cell. 2019 Jan 7;6(1):65-101. doi: 10.15698/mic2019.01.665. PubMed PMID: 30652106; PMCID: PMC6334232.
Needham PG, Guerriero CJ, Brodsky JL. Chaperoning Endoplasmic Reticulum-Associated Degradation (ERAD) and Protein Conformational Diseases. Cold Spring Harb Perspect Biol. 2019 Aug 1;11(8): doi: 10.1101/cshperspect.a033928. PubMed PMID: 30670468; PMCID: PMC6671943.
Tan X, Tong J, Wang YJ, Fletcher R, Schoen RE, Yu J, Shen L, Zhang L. BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5. Cancer Res. 2019 Mar 15;79(6):1191-1203. doi: 10.1158/0008-5472.CAN-18-3223. PubMed PMID: 30674532; PMCID: PMC6420862.
Tian H, Sparvero LJ, Blenkinsopp P, Amoscato AA, Watkins SC, Bayır H, Kagan VE, Winograd N. Secondary-Ion Mass Spectrometry Images Cardiolipins and Phosphatidylethanolamines at the Subcellular Level. Angew Chem Int Ed Engl. 2019 Mar 4;58(10):3156-3161. doi: 10.1002/anie.201814256. PubMed PMID: 30680861; PMCID: PMC6622167.
Skoko JJ, Attaran S, Neumann CA. Signals Getting Crossed in the Entanglement of Redox and Phosphorylation Pathways: Phosphorylation of Peroxiredoxin Proteins Sparks Cell Signaling. Antioxidants (Basel). 2019 Jan 23;8(2): doi: 10.3390/antiox8020029. PubMed PMID: 30678096; PMCID: PMC6406269.
Sehrawat A, Samanta SK, Hahm ER, St Croix C, Watkins S, Singh SV. Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics. Mitochondrion. 2019 Jul;47282-293. doi: 10.1016/j.mito.2019.01.003. PubMed PMID: 30685490; PMCID: PMC6599725.
Hopkins BL, Neumann CA. Redoxins as gatekeepers of the transcriptional oxidative stress response. Redox Biol. 2019 Feb;21101104. doi: 10.1016/j.redox.2019.101104. PubMed PMID: 30690320; PMCID: PMC6351230.
Smith NG, Gyanchandani R, Shah OS, Gurda GT, Lucas PC, Hartmaier RJ, Brufsky AM, Puhalla S, Bahreini A, Kota K, Wald AI, Nikiforov YE, Nikiforova MN, Oesterreich S, Lee AV. Targeted mutation detection in breast cancer using MammaSeq™. Breast Cancer Res. 2019 Feb 8;21(1):22. doi: 10.1186/s13058-019-1102-7. PubMed PMID: 30736836; PMCID: PMC6368740.
Minata M, Audia A, Shi J, Lu S, Bernstock J, Pavlyukov MS, Das A, Kim SH, Shin YJ, Lee Y, Koo H, Snigdha K, Waghmare I, Guo X, Mohyeldin A, Gallego-Perez D, Wang J, Chen D, Cheng P, Mukheef F, Contreras M, Reyes JF, Vaillant B, Sulman EP, Cheng SY, Markert JM, Tannous BA, Lu X, Kango-Singh M, Lee LJ, Nam DH, Nakano I, Bhat KP. Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation. Cell Rep. 2019 Feb 12;26(7):1893-1905.e7. doi: 10.1016/j.celrep.2019.01.076. PubMed PMID: 30759398; PMCID: PMC6594377.
Mikulska-Ruminska K, Shrivastava I, Krieger J, Zhang S, Li H, Bayır H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I. Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members. J Chem Inf Model. 2019 May 28;59(5):2496-2508. doi: 10.1021/acs.jcim.9b00006. PubMed PMID: 30762363; PMCID: PMC6541894.
Raza Q, Choi JY, Li Y, O'Dowd RM, Watkins SC, Chikina M, Hong Y, Clark NL, Kwiatkowski AV. Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila. PLoS Genet. 2019 Feb;15(2):e1007720. doi: 10.1371/journal.pgen.1007720. PubMed PMID: 30763317; PMCID: PMC6375579.
Nmezi B, Xu J, Fu R, Armiger TJ, Rodriguez-Bey G, Powell JS, Ma H, Sullivan M, Tu Y, Chen NY, Young SG, Stolz DB, Dahl KN, Liu Y, Padiath QS. Concentric organization of A- and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4307-4315. doi: 10.1073/pnas.1810070116. PubMed PMID: 30765529; PMCID: PMC6410836.
Fan XN, Zhang SW, Zhang SY, Zhu K, Lu S. Prediction of lncRNA-disease associations by integrating diverse heterogeneous information sources with RWR algorithm and positive pointwise mutual information. BMC Bioinformatics. 2019 Feb 19;20(1):87. doi: 10.1186/s12859-019-2675-y. PubMed PMID: 30782113; PMCID: PMC6381749.
D'Aiuto L, Bloom DC, Naciri JN, Smith A, Edwards TG, McClain L, Callio JA, Jessup M, Wood J, Chowdari K, Demers M, Abrahamson EE, Ikonomovic MD, Viggiano L, De Zio R, Watkins S, Kinchington PR, Nimgaonkar VL. Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells. J Virol. 2019 May 1;93(9): doi: 10.1128/JVI.00111-19. PubMed PMID: 30787148; PMCID: PMC6475775.
Zhang X, Fisher R, Shields D, Hou W, Franicola D, Wang H, Epperly MW, Rigatti L, Greenberger JS. Malignant Transformation of Fanconi Anemia Complementation Group D2-deficient (Fancd2 -/-) Hematopoietic Progenitor Cells by a Single HPV16 Oncogene. In Vivo. 2019 Mar-Apr;33(2):303-311. doi: 10.21873/invivo.11476. PubMed PMID: 30804107; PMCID: PMC6506306.
Morosky S, Wells AI, Lemon K, Evans AS, Schamus S, Bakkenist CJ, Coyne CB. The neonatal Fc receptor is a pan-echovirus receptor. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3758-3763. doi: 10.1073/pnas.1817341116. PubMed PMID: 30808762; PMCID: PMC6397586.
Nikiforov YE, Baloch ZW. Clinical validation of the ThyroSeq v3 genomic classifier in thyroid nodules with indeterminate FNA cytology. Cancer Cytopathol. 2019 Apr;127(4):225-230. doi: 10.1002/cncy.22112. PubMed PMID: 30811896; PMCID: PMC6519348.
Fischer DK, Saito A, Kline C, Cohen R, Watkins SC, Yamashita M, Ambrose Z. CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes. J Virol. 2019 May 1;93(9): doi: 10.1128/JVI.00214-19. PubMed PMID: 30814280; PMCID: PMC6475785.
Baldock RA, Pressimone CA, Baird JM, Khodakov A, Luong TT, Grundy MK, Smith CM, Karpenshif Y, Bratton-Palmer DS, Prakash R, Jasin M, Garcin EB, Gon S, Modesti M, Bernstein KA. RAD51D splice variants and cancer-associated mutations reveal XRCC2 interaction to be critical for homologous recombination. DNA Repair (Amst). 2019 Apr;7699-107. doi: 10.1016/j.dnarep.2019.02.008. PubMed PMID: 30836272; PMCID: PMC6508892.
Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, Gao X, Amoscato AA, Straub AC, Kagan VE, Dezfulian C, Bayır H. Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated With Outcome After Cardiac Arrest. Crit Care Med. 2019 Apr;47(4):e292-e300. doi: 10.1097/CCM.0000000000003636. PubMed PMID: 30855329; PMCID: PMC6622168.
Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, Yoon E, Lombard DB, Bild A, Mehta G, Romero I, Chiang CY, Landen C, Cravatt B, Hurley TD, Larsen SD, Buckanovich RJ. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6. doi: 10.1016/j.celrep.2019.02.032. PubMed PMID: 30865894.
Xu J, Liu Y. Imaging Higher-order Chromatin Structures in Single Cells Using Stochastic Optical Reconstruction Microscopy. Bio Protoc. 2019 Feb 5;9(3): doi: 10.21769/BioProtoc.3160. PubMed PMID: 30873426; PMCID: PMC6414075.
Braganza A, Quesnelle K, Bickta J, Reyes C, Wang Y, Jessup M, St Croix C, Arlotti J, Singh SV, Shiva S. Myoglobin induces mitochondrial fusion, thereby inhibiting breast cancer cell proliferation. J Biol Chem. 2019 May 3;294(18):7269-7282. doi: 10.1074/jbc.RA118.006673. PubMed PMID: 30872402; PMCID: PMC6509513.
Li M, Mandal A, Tyurin VA, DeLucia M, Ahn J, Kagan VE, van der Wel PCA. Surface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized Dynamics. Structure. 2019 May 7;27(5):806-815.e4. doi: 10.1016/j.str.2019.02.007. PubMed PMID: 30879887; PMCID: PMC6615723.
Harms A, Kansara S, Stach C, Richardson PA, Chen G, Lai S, Sikora AG, Parke R, Donovan D, Chiao E, Skinner H, Sandulache VC. Swallowing Function in Survivors of Oropharyngeal Cancer Is Associated With Advanced T Classification. Ann Otol Rhinol Laryngol. 2019 Aug;128(8):696-703. doi: 10.1177/0003489419839091. PubMed PMID: 30913911.
Adamik J, Roodman GD, Galson DL. Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease. JBMR Plus. 2019 Mar;3(3):e10183. doi: 10.1002/jbm4.10183. PubMed PMID: 30918921; PMCID: PMC6419609.
Tyurina YY, Tyurin VA, Anthonymuthu T, Amoscato AA, Sparvero LJ, Nesterova AM, Baynard ML, Sun W, He R, Khaitovich P, Vladimirov YA, Gabrilovich DI, Bayır H, Kagan VE. "Redox lipidomics technology: Looking for a needle in a haystack". Chem Phys Lipids. 2019 Jul;22193-107. doi: 10.1016/j.chemphyslip.2019.03.012. PubMed PMID: 30928338; PMCID: PMC6714565.
Singh M, Tian XJ, Donnenberg VS, Watson AM, Zhang J, Stabile LP, Watkins SC, Xing J, Sant S. Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration. Cancer Res. 2019 Jun 1;79(11):2962-2977. doi: 10.1158/0008-5472.CAN-18-3151. PubMed PMID: 30952634; PMCID: PMC6548579.
Veglia F, Tyurin VA, Blasi M, De Leo A, Kossenkov AV, Donthireddy L, To TKJ, Schug Z, Basu S, Wang F, Ricciotti E, DiRusso C, Murphy ME, Vonderheide RH, Lieberman PM, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Lin C, Nefedova Y, Black P, Kagan VE, Gabrilovich DI. Fatty acid transport protein 2 reprograms neutrophils in cancer. Nature. 2019 May;569(7754):73-78. doi: 10.1038/s41586-019-1118-2. PubMed PMID: 30996346; PMCID: PMC6557120.
Wang W, Taft DA, Chen YJ, Zhang J, Wallace CT, Xu M, Watkins SC, Xing J. Learn to segment single cells with deep distance estimator and deep cell detector. Comput Biol Med. 2019 May;108133-141. doi: 10.1016/j.compbiomed.2019.04.006. PubMed PMID: 31005005; PMCID: PMC6781873.
Pisapia P, Malapelle U, Roma G, Saddar S, Zheng Q, Pepe F, Bruzzese D, Vigliar E, Bellevicine C, Luthra R, Nikiforov YE, Mayo-de-Las-Casas C, Molina-Vila MA, Rosell R, Bihl M, Savic S, Bubendorf L, de Biase D, Tallini G, Hwang DH, Sholl LM, Vander Borght S, Weynand B, Stieber D, Vielh P, Rappa A, Barberis M, Fassan M, Rugge M, De Andrea CE, Lozano MD, Lupi C, Fontanini G, Schmitt F, Dumur CI, Bisig B, Bongiovanni M, Merkelbach-Bruse S, Büttner R, Nikiforova MN, Roy-Chowdhuri S, Troncone G, Molecular Cytopathology Meeting Group.. Consistency and reproducibility of next-generation sequencing in cytopathology: A second worldwide ring trial study on improved cytological molecular reference specimens. Cancer Cytopathol. 2019 May;127(5):285-296. doi: 10.1002/cncy.22134. PubMed PMID: 31021538.
Ma H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019 Apr;5(4):eaaw0683. doi: 10.1126/sciadv.aaw0683. PubMed PMID: 31032419; PMCID: PMC6486217.
Liang L, Chen V, Zhu K, Fan X, Lu X, Lu S. Integrating data and knowledge to identify functional modules of genes: a multilayer approach. BMC Bioinformatics. 2019 May 2;20(1):225. doi: 10.1186/s12859-019-2800-y. PubMed PMID: 31046665; PMCID: PMC6498600.
Doonan LM, Guerriero CJ, Preston GM, Buck TM, Khazanov N, Fisher EA, Senderowitz H, Brodsky JL. Hsp104 facilitates the endoplasmic-reticulum-associated degradation of disease-associated and aggregation-prone substrates. Protein Sci. 2019 Jul;28(7):1290-1306. doi: 10.1002/pro.3636. PubMed PMID: 31050848; PMCID: PMC6566541.
Werner HM, Estabrooks SK, Preston GM, Brodsky JL, Horne WS. Exploring the Functional Consequences of Protein Backbone Alteration in Ubiquitin through Native Chemical Ligation. Chembiochem. 2019 Sep 16;20(18):2346-2350. doi: 10.1002/cbic.201900225. PubMed PMID: 31059184; PMCID: PMC6752966.
Larsen MB, Perez Verdaguer M, Schmidt BF, Bruchez MP, Watkins SC, Sorkin A. Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis. Elife. 2019 May 8;8 doi: 10.7554/eLife.46135. PubMed PMID: 31066673; PMCID: PMC6533059.
Yu C, Liu Q, Chen C, Yu J, Wang J. Landscape perspectives of tumor, EMT, and development. Phys Biol. 2019 Jul 5;16(5):051003. doi: 10.1088/1478-3975/ab2029. PubMed PMID: 31067516.
Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death. J Leukoc Biol. 2019 Jul;106(1):57-81. doi: 10.1002/JLB.3MIR0119-004RR. PubMed PMID: 31071242; PMCID: PMC6626990.
Ellison MA, Lederer AR, Warner MH, Mavrich TN, Raupach EA, Heisler LE, Nislow C, Lee MT, Arndt KM. The Paf1 Complex Broadly Impacts the Transcriptome of Saccharomyces cerevisiae. Genetics. 2019 Jul;212(3):711-728. doi: 10.1534/genetics.119.302262. PubMed PMID: 31092540; PMCID: PMC6614894.
Fouquerel E, Barnes RP, Uttam S, Watkins SC, Bruchez MP, Opresko PL. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019 Jul 11;75(1):117-130.e6. doi: 10.1016/j.molcel.2019.04.024. PubMed PMID: 31101499; PMCID: PMC6625854.
Luu HN, Qi M, Wang R, Adams-Haduch J, Miljkovic I, Opresko PL, Jin A, Koh WP, Yuan JM. Association Between Leukocyte Telomere Length and Colorectal Cancer Risk in the Singapore Chinese Health Study. Clin Transl Gastroenterol. 2019 May 22;10(5):1-9. doi: 10.14309/ctg.0000000000000043. PubMed PMID: 31117113; PMCID: PMC6602767.
Piccirillo AR, Hyzny EJ, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM. The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection. J Immunol. 2019 Jul 1;203(1):117-126. doi: 10.4049/jimmunol.1801585. PubMed PMID: 31127034; PMCID: PMC6581627.
Xu J, Liu Y. A guide to visualizing the spatial epigenome with super-resolution microscopy. FEBS J. 2019 Aug;286(16):3095-3109. doi: 10.1111/febs.14938. PubMed PMID: 31127980; PMCID: PMC6699889.
Fouquerel E, Barnes RP, Wang H, Opresko PL. Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA. Methods Mol Biol. 2019;1999295-306. doi: 10.1007/978-1-4939-9500-4_20. PubMed PMID: 31127586; PMCID: PMC6886745.
Nechemia-Arbely Y, Miga KH, Shoshani O, Aslanian A, McMahon MA, Lee AY, Fachinetti D, Yates JR 3rd, Ren B, Cleveland DW. DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres. Nat Cell Biol. 2019 Jun;21(6):743-754. doi: 10.1038/s41556-019-0331-4. PubMed PMID: 31160708; PMCID: PMC7015266.
Uttam S, Hashash JG, LaFace J, Binion D, Regueiro M, Hartman DJ, Brand RE, Liu Y. Three-Dimensional Nanoscale Nuclear Architecture Mapping of Rectal Biopsies Detects Colorectal Neoplasia in Patients with Inflammatory Bowel Disease. Cancer Prev Res (Phila). 2019 Aug;12(8):527-538. doi: 10.1158/1940-6207.CAPR-19-0024. PubMed PMID: 31164345; PMCID: PMC6677599.
Bakkenist CJ, Czambel RK, Lin Y, Yates NA, Zeng X, Shogan J, Schmitz JC. Quantitative analysis of ATM phosphorylation in lymphocytes. DNA Repair (Amst). 2019 Aug;801-7. doi: 10.1016/j.dnarep.2019.06.002. PubMed PMID: 31176958; PMCID: PMC6708498.
Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E, Watkins SC, Bakkenist CJ. An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13374-13383. doi: 10.1073/pnas.1903418116. PubMed PMID: 31209037; PMCID: PMC6613105.
Cucinotta CE, Hildreth AE, McShane BM, Shirra MK, Arndt KM. The nucleosome acidic patch directly interacts with subunits of the Paf1 and FACT complexes and controls chromatin architecture in vivo. Nucleic Acids Res. 2019 Sep 19;47(16):8410-8423. doi: 10.1093/nar/gkz549. PubMed PMID: 31226204; PMCID: PMC6895269.
Shao L, Hou W, Scharping NE, Vendetti FP, Srivastava R, Roy CN, Menk AV, Wang Y, Chauvin JM, Karukonda P, Thorne SH, Hornung V, Zarour HM, Bakkenist CJ, Delgoffe GM, Sarkar SN. IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell. Cancer Immunol Res. 2019 Aug;7(8):1258-1266. doi: 10.1158/2326-6066.CIR-18-0711. PubMed PMID: 31239318; PMCID: PMC6677597.
Boos LA, Schmitt A, Moch H, Komminoth P, Simillion C, Marinoni I, Nikiforov YE, Nikiforova MN, Perren A, Dettmer MS. MiRNAs Are Involved in Tall Cell Morphology in Papillary Thyroid Carcinoma. Cancers (Basel). 2019 Jun 25;11(6): doi: 10.3390/cancers11060885. PubMed PMID: 31242620; PMCID: PMC6628239.
Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H, Brodsky JL, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science. 2019 Jul 5;365(6448):53-60. doi: 10.1126/science.aau9263. PubMed PMID: 31273116.
Cai C, Cooper GF, Lu KN, Ma X, Xu S, Zhao Z, Chen X, Xue Y, Lee AV, Clark N, Chen V, Lu S, Chen L, Yu L, Hochheiser HS, Jiang X, Wang QJ, Lu X. Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference. PLoS Comput Biol. 2019 Jul;15(7):e1007088. doi: 10.1371/journal.pcbi.1007088. PubMed PMID: 31276486; PMCID: PMC6650088.
Nikitski AV, Rominski SL, Condello V, Kaya C, Wankhede M, Panebianco F, Yang H, Altschuler DL, Nikiforov YE. Mouse Model of Thyroid Cancer Progression and Dedifferentiation Driven by STRN-ALK Expression and Loss of p53: Evidence for the Existence of Two Types of Poorly Differentiated Carcinoma. Thyroid. 2019 Oct;29(10):1425-1437. doi: 10.1089/thy.2019.0284. PubMed PMID: 31298630; PMCID: PMC6797076.
Roy S, Agnihotri S, El Hallani S, Ernst WL, Wald AI, Santana Dos Santos L, Hamilton RL, Horbinski CM, Wadhwani NR, Born DE, Pollack IF, Nikiforov YE, Nikiforova MN. Clinical Utility of GlioSeq Next-Generation Sequencing Test in Pediatric and Young Adult Patients With Brain Tumors. J Neuropathol Exp Neurol. 2019 Jun 10; doi: 10.1093/jnen/nlz055. PubMed PMID: 31298284.
Han S, Ehrhardt J Jr, Shukla S, Elkbuli A, Nikiforov YE, Gulec SA. A Case of Papillary Thyroid Carcinoma and Kostmann Syndrome: A Genomic Theranostic Approach for Comprehensive Treatment. Am J Case Rep. 2019 Jul 16;201027-1034. doi: 10.12659/AJCR.916143. PubMed PMID: 31308356; PMCID: PMC6647623.
Sun J, Wang C, Zhang Y, Xu L, Fang W, Zhu Y, Zheng Y, Chen X, Xie X, Hu X, Hu W, Zheng J, Li P, Yu J, Mei Z, Cai X, Wang B, Hu Z, Shu Y, Shen H, Gu Y. Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases. Nat Commun. 2019 Jul 18;10(1):3190. doi: 10.1038/s41467-019-10987-3. PubMed PMID: 31320627; PMCID: PMC6639368.
Ma H, Wang P, Shang D, Liu Y. Spatial-domain low-coherence quantitative phase microscopy to improve the cytological diagnosis of pancreatic cancer. J Investig Med. 2020 Jan;68(1):60-67. doi: 10.1136/jim-2019-000997. PubMed PMID: 31324696.
Leonard BC, Lee ED, Bhola NE, Li H, Sogaard KK, Bakkenist CJ, Grandis JR, Johnson DE. ATR inhibition sensitizes HPV- and HPV+ head and neck squamous cell carcinoma to cisplatin. Oral Oncol. 2019 Aug;9535-42. doi: 10.1016/j.oraloncology.2019.05.028. PubMed PMID: 31345392; PMCID: PMC6827881.
Nikiforova MN, Nikiforov YE, Ohori NP. GLIS rearrangements in thyroid nodules: A key to preoperative diagnosis of hyalinizing trabecular tumor. Cancer Cytopathol. 2019 Sep;127(9):560-566. doi: 10.1002/cncy.22163. PubMed PMID: 31373774.
Panebianco F, Nikitski AV, Nikiforova MN, Nikiforov YE. Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer. Cancer Med. 2019 Oct;8(13):5831-5839. doi: 10.1002/cam4.2467. PubMed PMID: 31408918; PMCID: PMC6792496.
Borrelli N, Panebianco F, Condello V, Barletta JA, Kaya C, Yip L, Nikiforova MN, Nikiforov YE. Characterization of Activating Mutations of the MEK1 Gene in Papillary Thyroid Carcinomas. Thyroid. 2019 Sep;29(9):1279-1285. doi: 10.1089/thy.2019.0065. PubMed PMID: 31407636; PMCID: PMC6913803.
Malik N, Nikitski AV, Klam E, Hunt J, Witt B, Chadwick B, Nikiforov YE, Abraham D. MOLECULAR PROFILE AND CLINICAL OUTCOMES IN DIFFERENTIATED THYROID CANCER PATIENTS PRESENTING WITH BONE METASTASIS. Endocr Pract. 2019 Dec;25(12):1255-1262. doi: 10.4158/EP-2019-0265. PubMed PMID: 31412230.
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