Viral Markers
. High IgG titers against EBV glycoprotein 42 correlate with lower risk of nasopharyngeal carcinoma. J Clin Invest. 2025-02-17;135(4): doi: 10.1172/JCI189207. PubMed PMID: 39959976; PMCID: PMC11827836.
. The Epstein-Barr virus nuclear antigen 1 variant associated with nasopharyngeal carcinoma defines the sequence criteria for serologic risk prediction. Clin Cancer Res. 2024-11-15; doi: 10.1158/1078-0432.CCR-24-1142. PubMed PMID: 39264275; PMCID: PMC11567791.
. The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation. Immunity. 2024-08-13; doi: 10.1016/j.immuni.2024.06.003. PubMed PMID: 38955184; PMCID: PMC11324410.
. An IRF2-Expressing Oncolytic Virus Changes the Susceptibility of Tumor Cells to Antitumor T cells and Promotes Tumor Clearance. Cancer Immunol Res. 2024-06-04; doi: 10.1158/2326-6066.CIR-23-0573. PubMed PMID: 38517470; PMCID: PMC11150089.
. Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production. Immunity. 2024-03-12;57(3):446-461.e7. doi: 10.1016/j.immuni.2024.02.002. PubMed PMID: 38423012; PMCID: PMC10939734.
. Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases. Proc Natl Acad Sci U S A. 2023-12-19;120(51):e2316467120. doi: 10.1073/pnas.2316467120. PubMed PMID: 38079542; PMCID: PMC10740393.
. METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle. Cell Death Dis. 2023-09-06;14(9):591. doi: 10.1038/s41419-023-06121-3. PubMed PMID: 37673880; PMCID: PMC10482891.
. Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity. Proc Natl Acad Sci U S A. 2023-07-25;120(30):e2308010120. doi: 10.1073/pnas.2308010120. PubMed PMID: 37459531; PMCID: PMC10372695.
. Long-acting antiretrovirals and HIV treatment adherence. Lancet HIV. 2023-05-01;10(5):e332-e342. doi: 10.1016/S2352-3018(23)00051-6. PubMed PMID: 37062293; PMCID: PMC10734401.
. Characterization of Viruses in Phase 3 and Phase 3b Trials (the Ring Study and the Dapivirine Ring Extended Access and Monitoring Trial) of the Dapivirine Vaginal Ring for Human Immunodeficiency Virus Type 1 Infection Risk Reduction. Clin Infect Dis. 2023-03-21;76(6):996-1002. doi: 10.1093/cid/ciac875. PubMed PMID: 36345569.
. Clinical Presentation, Treatment Response, and Virology Outcomes of Women Who Seroconverted in the Dapivirine Vaginal Ring Trials-The Ring Study and DREAM. Clin Infect Dis. 2023-02-08;76(3):389-397. doi: 10.1093/cid/ciac804. PubMed PMID: 36189636; PMCID: PMC10169386.
. Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp). J Med Virol. 2023-01-01;95(1):e28246. doi: 10.1002/jmv.28246. PubMed PMID: 36271490; PMCID: PMC9874566.
. Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma. Clin Cancer Res. 2022-12-01;28(23):5221-5230. doi: 10.1158/1078-0432.CCR-22-1600. PubMed PMID: 36165913; PMCID: PMC9722633.
. Time to Viral Rebound After Interruption of Modern Antiretroviral Therapies. Clin Infect Dis. 2022-03-09;74(5):865-870. doi: 10.1093/cid/ciab541. PubMed PMID: 34117753; PMCID: PMC8906742.
. Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas. Sci Adv. 2021-10-15;7(42):eabi8795. doi: 10.1126/sciadv.abi8795. PubMed PMID: 34644108; PMCID: PMC8514100.
. The emerging plasticity of SARS-CoV-2. Science. 2021-03-26;371(6536):1306-1308. doi: 10.1126/science.abg4493. PubMed PMID: 33766871.
. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nat Commun. 2021-02-16;12(1):1055. doi: 10.1038/s41467-021-21206-3. PubMed PMID: 33594058; PMCID: PMC7887217.
. Proteomic approach to discover human cancer viruses from formalin-fixed tissues. JCI Insight. 2020-11-19;5(22): doi: 10.1172/jci.insight.143003. PubMed PMID: 33055416; PMCID: PMC7710300.
. HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus. J Clin Invest. 2020-11-02;130(11):5847-5857. doi: 10.1172/JCI138099. PubMed PMID: 33016926; PMCID: PMC7598056.
. Diverse Human Immunodeficiency Virus-1 Drug Resistance Profiles at Screening for ACTG A5288: A Study of People Experiencing Virologic Failure on Second-line Antiretroviral Therapy in Resource-limited Settings. Clin Infect Dis. 2020-10-23;71(7):e170-e177. doi: 10.1093/cid/ciz1116. PubMed PMID: 31724034; PMCID: PMC7583422.
. Yottixel - An Image Search Engine for Large Archives of Histopathology Whole Slide Images. Med Image Anal. 2020-10-01;65101757. doi: 10.1016/j.media.2020.101757. PubMed PMID: 32623275.
. An artificial intelligence algorithm for prostate cancer diagnosis in whole slide images of core needle biopsies: a blinded clinical validation and deployment study. Lancet Digit Health. 2020-08-01;2(8):e407-e416. doi: 10.1016/S2589-7500(20)30159-X. PubMed PMID: 33328045.
. Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence. NPJ Digit Med. 2020-03-10;331. doi: 10.1038/s41746-020-0238-2. PubMed PMID: 32195366; PMCID: PMC7064517.
. Persistent HIV-infected cells in cerebrospinal fluid are associated with poorer neurocognitive performance. J Clin Invest. 2019-07-15;129(8):3339-3346. doi: 10.1172/JCI127413. PubMed PMID: 31305262; PMCID: PMC6668666.
. Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. J Clin Invest. 2019-07-15;129(8):3310-3323. doi: 10.1172/JCI127166. PubMed PMID: 31305263; PMCID: PMC6668677.
. Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP): Update and Diagnostic Considerations-a Review. Endocr Pathol. 2019-06-01;30(2):155-162. doi: 10.1007/s12022-019-9574-7. PubMed PMID: 30953289; PMCID: PMC7477663.
. Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production. Immunity. 2019-01-15;50(1):51-63.e5. doi: 10.1016/j.immuni.2018.12.013. PubMed PMID: 30635239; PMCID: PMC6342484.
. Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4(+) T cells. Nat Med. 2017-07-01;23(7):885-889. doi: 10.1038/nm.4347. PubMed PMID: 28553933; PMCID: PMC5505781.
. TAFRO syndrome: An atypical variant of KSHV-negative multicentric Castleman disease. Am J Hematol. 2016-02-01;91(2):171-2. doi: 10.1002/ajh.24274. PubMed PMID: 26663467.
. Microenvironment and HIV-related lymphomagenesis. Semin Cancer Biol. 2015-10-01;3452-7. doi: 10.1016/j.semcancer.2015.06.002. PubMed PMID: 26118690.
. Clinical microbiology informatics. Clin Microbiol Rev. 2014-10-01;27(4):1025-47. doi: 10.1128/CMR.00049-14. PubMed PMID: 25278581; PMCID: PMC4187636.
. Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor. Immunity. 2014-06-19;40(6):936-48. doi: 10.1016/j.immuni.2014.05.007. PubMed PMID: 24931123; PMCID: PMC4101812.
. The conundrum of causality in tumor virology: the cases of KSHV and MCV. Semin Cancer Biol. 2014-06-01;264-12. doi: 10.1016/j.semcancer.2013.11.001. PubMed PMID: 24304907; PMCID: PMC4040341.
