Publications

Strickler JH, Satake H, George TJ, Yaeger R, Hollebecque A, Garrido-Laguna I, Schuler M, Burns TF, Coveler AL, Falchook GS, Vincent M, Sunakawa Y, Dahan L, Bajor D, Rha SY, Lemech C, Juric D, Rehn M, Ngarmchamnanrith G, Jafarinasabian P, Tran Q, Hong DS. Sotorasib in KRAS p.G12C-Mutated Advanced Pancreatic Cancer. N Engl J Med. 2023-01-05;388(1):33-43. doi: 10.1056/NEJMoa2208470. PubMed PMID: 36546651.

Phan T, Boes S, McCullough M, Gribschaw J, Wells A. Mini-evaluation of the Lyra SARS-CoV-2 assay to detect Omicron BA.1 and BA.2 in nasopharyngeal swabs. J Clin Virol Plus. 2022-11-01;2(4):100118. doi: 10.1016/j.jcvp.2022.100118. PubMed PMID: 36277996; PMCID: PMC9578329.

Weiss KR, Bailey KM. A Druggable Rheostat for Ewing Sarcoma? Clin Cancer Res. 2022-10-14;28(20):4360-4362. doi: 10.1158/1078-0432.CCR-22-1794. PubMed PMID: 35921177; PMCID: PMC9588653.

Manzo J, Puhalla S, Pahuja S, Ding F, Lin Y, Appleman L, Tawbi H, Stoller R, Lee JJ, Diergaarde B, Kiesel BF, Yu J, Tan AR, Belani CP, Chew H, Garcia AA, Morgan RJ, Wahner Hendrickson AE, Visscher DW, Hurley RM, Kaufmann SH, Swisher EM, Oesterreich S, Katz T, Ji J, Zhang Y, Parchment RE, Chen A, Duan W, Giranda V, Shepherd SP, Ivy SP, Chu E, Beumer JH, ETCTN-8282 study team. A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer. Cancer Chemother Pharmacol. 2022-05-01;89(5):721-735. doi: 10.1007/s00280-022-04430-6. PubMed PMID: 35435472; PMCID: PMC9116722.

Shah OS, Soran A, Sahin M, Knapick BA, Ugras S, Celik E, Lucas PC, Lee AV. Identifying Genomic Alterations in Patients With Stage IV Breast Cancer Using MammaSeq: An International Collaborative Study. Clin Breast Cancer. 2021-06-01;21(3):210-217. doi: 10.1016/j.clbc.2020.08.009. PubMed PMID: 33191115.

Zou M, Jiang D, Wu T, Zhang X, Zhao Y, Wu D, Sun W, Cui J, Moreland L, Li G. Post-GWAS functional studies reveal an RA-associated CD40-induced NF-kB signal transduction and transcriptional regulation network targeted by class II HDAC inhibitors. Hum Mol Genet. 2021-05-28;30(9):823-835. doi: 10.1093/hmg/ddab032. PubMed PMID: 33517445; PMCID: PMC8161515.

Youngblood MW, Miyagishima DF, Jin L, Gupte T, Li C, Duran D, Montejo JD, Zhao A, Sheth A, Tyrtova E, Özduman K, Iacoangeli F, Peyre M, Boetto J, Pease M, Avşar T, Huttner A, Bilguvar K, Kilic T, Pamir MN, Amankulor N, Kalamarides M, Erson-Omay EZ, Günel M, Moliterno J. Associations of meningioma molecular subgroup and tumor recurrence. Neuro Oncol. 2021-05-05;23(5):783-794. doi: 10.1093/neuonc/noaa226. PubMed PMID: 33068421; PMCID: PMC8099468.

Wang H, Lu J, Mandel JA, Zhang W, Schwalbe M, Gorka J, Liu Y, Marburger B, Wang J, Ranganathan S, Prochownik EV. Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas. Cell Mol Gastroenterol Hepatol. 2021-02-20;12(1):199-228. doi: 10.1016/j.jcmgh.2021.02.004. PubMed PMID: 33618031; PMCID: PMC8102178.

Lv S, Song Q, Chen G, Cheng E, Chen W, Cole R, Wu Z, Pascal LE, Wang K, Wipf P, Nelson JB, Wei Q, Huang W, Wang Z. Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer. J Clin Invest. 2021-02-15;131(4): doi: 10.1172/JCI141335. PubMed PMID: 33332287; PMCID: PMC7880411.

Stabile LP, Kumar V, Gaither-Davis A, Huang EH, Vendetti FP, Devadassan P, Dacic S, Bao R, Steinman RA, Burns TF, Bakkenist CJ. Syngeneic tobacco carcinogen-induced mouse lung adenocarcinoma model exhibits PD-L1 expression and high tumor mutational burden. JCI Insight. 2021-02-08;6(3): doi: 10.1172/jci.insight.145307. PubMed PMID: 33351788; PMCID: PMC7934870.

Huddle BC, Grimley E, Chtcherbinine M, Buchman CD, Takahashi C, Debnath B, McGonigal SC, Mao S, Li S, Felton J, Pan S, Wen B, Sun D, Neamati N, Buckanovich RJ, Hurley TD, Larsen SD. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur J Med Chem. 2021-02-05;211113060. doi: 10.1016/j.ejmech.2020.113060. PubMed PMID: 33341649; PMCID: PMC7855449.

Arnesen S, Blanchard Z, Williams MM, Berrett KC, Li Z, Oesterreich S, Richer JK, Gertz J. Estrogen Receptor Alpha Mutations in Breast Cancer Cells Cause Gene Expression Changes through Constant Activity and Secondary Effects. Cancer Res. 2021-02-01;81(3):539-551. doi: 10.1158/0008-5472.CAN-20-1171. PubMed PMID: 33184109; PMCID: PMC7854489.

Williams MM, Spoelstra NS, Arnesen S, O'Neill KI, Christenson JL, Reese J, Torkko KC, Goodspeed A, Rosas E, Hanamura T, Sams SB, Li Z, Oesterreich S, Riggins RB, Jacobsen BM, Elias A, Gertz J, Richer JK. Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of ESR1-Mutant Breast Cancer. Cancer Res. 2021-02-01;81(3):732-746. doi: 10.1158/0008-5472.CAN-20-1200. PubMed PMID: 33184106; PMCID: PMC7854521.

Varešlija D, Ward E, Purcell SP, Cosgrove NS, Cocchiglia S, O'Halloran PJ, Charmsaz S, Bane FT, Brett FM, Farrell M, Cryan J, Beausang A, Hudson L, Turnbul AK, Dixon JM, Hill ADK, Priedigkeit N, Oesterreich S, Lee AV, Sims AH, Redmond AM, Carroll JS, Young LS. Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype. Oncogene. 2021-02-01;40(7):1318-1331. doi: 10.1038/s41388-020-01606-3. PubMed PMID: 33420368; PMCID: PMC7892341.

Chen F, Ding K, Priedigkeit N, Elangovan A, Levine KM, Carleton N, Savariau L, Atkinson JM, Oesterreich S, Lee AV. Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells. Cancer Res. 2021-01-15;81(2):268-281. doi: 10.1158/0008-5472.CAN-20-0696. PubMed PMID: 33148662; PMCID: PMC7856056.

Wang H, Lu J, Chen X, Schwalbe M, Gorka JE, Mandel JA, Wang J, Goetzman ES, Ranganathan S, Dobrowolski SF, Prochownik EV. Acquired deficiency of peroxisomal dicarboxylic acid catabolism is a metabolic vulnerability in hepatoblastoma. J Biol Chem. 2021-01-01;296100283. doi: 10.1016/j.jbc.2021.100283. PubMed PMID: 33450224; PMCID: PMC7948956.

Pascal LE, Mizoguchi S, Chen W, Rigatti LH, Igarashi T, Dhir R, Tyagi P, Wu Z, Yang Z, de Groat WC, DeFranco DB, Yoshimura N, Wang Z. Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity. Endocrinology. 2021-01-01;162(1): doi: 10.1210/endocr/bqaa212. PubMed PMID: 33211830; PMCID: PMC7745638.

Zhao W, Li J, Chen MM, Luo Y, Ju Z, Nesser NK, Johnson-Camacho K, Boniface CT, Lawrence Y, Pande NT, Davies MA, Herlyn M, Muranen T, Zervantonakis IK, von Euw E, Schultz A, Kumar SV, Korkut A, Spellman PT, Akbani R, Slamon DJ, Gray JW, Brugge JS, Lu Y, Mills GB, Liang H. Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines. Cancer Cell. 2020-12-14;38(6):829-843.e4. doi: 10.1016/j.ccell.2020.10.008. PubMed PMID: 33157050; PMCID: PMC7738392.

Burns TF, Borghaei H, Ramalingam SS, Mok TS, Peters S. Targeting KRAS-Mutant Non-Small-Cell Lung Cancer: One Mutation at a Time, With a Focus on KRAS G12C Mutations. J Clin Oncol. 2020-12-10;38(35):4208-4218. doi: 10.1200/JCO.20.00744. PubMed PMID: 33104438; PMCID: PMC7723684.

Ejaz A, Yang KS, Venkatesh KP, Chinnapaka S, Kokai LE, Rubin JP. The Impact of Human Lipoaspirate and Adipose Tissue-Derived Stem Cells Contact Culture on Breast Cancer Cells: Implications in Breast Reconstruction. Int J Mol Sci. 2020-12-01;21(23): doi: 10.3390/ijms21239171. PubMed PMID: 33271950; PMCID: PMC7731376.

Charmsaz S, Doherty B, Cocchiglia S, Varešlija D, Marino A, Cosgrove N, Marques R, Priedigkeit N, Purcell S, Bane F, Bolger J, Byrne C, O'Halloran PJ, Brett F, Sheehan K, Brennan K, Hopkins AM, Keelan S, Jagust P, Madden S, Martinelli C, Battaglini M, Oesterreich S, Lee AV, Ciofani G, Hill ADK, Young LS. ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis. BMC Med. 2020-11-19;18(1):349. doi: 10.1186/s12916-020-01806-4. PubMed PMID: 33208158; PMCID: PMC7677775.

Ramasamy T, Chen X, Qin B, Johnson DE, Grandis JR, Villanueva FS. STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors. PLoS One. 2020-11-18;15(11):e0242264. doi: 10.1371/journal.pone.0242264. PubMed PMID: 33206698; PMCID: PMC7673576.

Shackleford MT, Rao DM, Bordeaux EK, Hicks HM, Towers CG, Sottnik JL, Oesterreich S, Sikora MJ. Estrogen Regulation of mTOR Signaling and Mitochondrial Function in Invasive Lobular Carcinoma Cell Lines Requires WNT4. Cancers (Basel). 2020-10-12;12(10): doi: 10.3390/cancers12102931. PubMed PMID: 33053661; PMCID: PMC7650584.

Korentzelos D, Clark AM, Wells A. A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer. Int J Mol Sci. 2020-10-03;21(19): doi: 10.3390/ijms21197304. PubMed PMID: 33022920; PMCID: PMC7582598.

Rehnke RD, Schusterman MA 2nd, Clarke JM, Price BC, Waheed U, Debski RE, Badylak SF, Rubin JP. Breast Reconstruction Using a Three-Dimensional Absorbable Mesh Scaffold and Autologous Fat Grafting: A Composite Strategy Based on Tissue-Engineering Principles. Plast Reconstr Surg. 2020-10-01;146(4):409e-413e. doi: 10.1097/PRS.0000000000007172. PubMed PMID: 32969997.

Tao Y, Lei H, Lee AV, Ma J, Schwartz R. Neural Network Deconvolution Method for Resolving Pathway-Level Progression of Tumor Clonal Expression Programs With Application to Breast Cancer Brain Metastases. Front Physiol. 2020-09-04;111055. doi: 10.3389/fphys.2020.01055. PubMed PMID: 33013452; PMCID: PMC7499245.

Grundy MK, Buckanovich RJ, Bernstein KA. Regulation and pharmacological targeting of RAD51 in cancer. NAR Cancer. 2020-09-01;2(3):zcaa024. doi: 10.1093/narcan/zcaa024. PubMed PMID: 33015624; PMCID: PMC7520849.

Dwivedi SKD, Rao G, Dey A, Buechel M, Zhang Y, Zhang M, Yang D, Mukherjee P, Bhattacharya R. Targeting the TGFβ pathway in uterine carcinosarcoma. Cell Stress. 2020-08-25;4(11):252-260. doi: 10.15698/cst2020.11.234. PubMed PMID: 33150300; PMCID: PMC7590842.

Chattopadhyay A, Iwema CL, Epstein BA, Lee AV, Levine AS. Molecular Biology Information Service: an innovative medical library-based bioinformatics support service for biomedical researchers. Brief Bioinform. 2020-05-21;21(3):876-884. doi: 10.1093/bib/bbz035. PubMed PMID: 30949666.

Zhang Q, Li X, Cui K, Liu C, Wu M, Prochownik EV, Li Y. The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor development. Cell Death Differ. 2020-02-01;27(2):420-433. doi: 10.1038/s41418-019-0363-0. PubMed PMID: 31186535; PMCID: PMC7205897.

Ma B, Wells A, Clark AM. The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment. Semin Cancer Biol. 2020-02-01;60138-147. doi: 10.1016/j.semcancer.2019.07.021. PubMed PMID: 31376430; PMCID: PMC6992520.

Cillo AR, Kürten CHL, Tabib T, Qi Z, Onkar S, Wang T, Liu A, Duvvuri U, Kim S, Soose RJ, Oesterreich S, Chen W, Lafyatis R, Bruno TC, Ferris RL, Vignali DAA. Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer. Immunity. 2020-01-14;52(1):183-199.e9. doi: 10.1016/j.immuni.2019.11.014. PubMed PMID: 31924475; PMCID: PMC7201194.

Somasundaram A, Rothenberger NJ, Stabile LP. The Impact of Estrogen in the Tumor Microenvironment. Adv Exp Med Biol. 2020-01-01;127733-52. doi: 10.1007/978-3-030-50224-9_2. PubMed PMID: 33119863.

Weiss KR. ASO Author Reflections: Tumor Painting with Indocyanine Green Dye: Why not Sarcoma, too? Ann Surg Oncol. 2019-12-01;26(Suppl 3):628-629. doi: 10.1245/s10434-019-07397-6. PubMed PMID: 31187368.

McAuley JR, Bailey KM, Ekambaram P, Klei LR, Kang H, Hu D, Freeman TJ, Concel VJ, Hubel NE, Lee JL, Klei HB, Cheng J, Sekar P, Bridwell RE, Covic L, Lucas PC, McAllister-Lucas LM. MALT1 is a critical mediator of PAR1-driven NF-κB activation and metastasis in multiple tumor types. Oncogene. 2019-12-01;38(49):7384-7398. doi: 10.1038/s41388-019-0958-4. PubMed PMID: 31420608.

Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X. Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice. Hepatology. 2019-12-01;70(6):2003-2017. doi: 10.1002/hep.30556. PubMed PMID: 30737831; PMCID: PMC7206928.

Swain SM, Tang G, Lucas PC, Robidoux A, Goerlitz D, Harris BT, Bandos H, Geyer CE Jr, Rastogi P, Mamounas EP, Wolmark N. Pathologic complete response and outcomes by intrinsic subtypes in NSABP B-41, a randomized neoadjuvant trial of chemotherapy with trastuzumab, lapatinib, or the combination. Breast Cancer Res Treat. 2019-11-01;178(2):389-399. doi: 10.1007/s10549-019-05398-3. PubMed PMID: 31428908; PMCID: PMC6797698.

Abraham J, Montero AJ, Jankowitz RC, Salkeni MA, Beumer JH, Kiesel BF, Piette F, Adamson LM, Nagy RJ, Lanman RB, Sperinde J, Huang W, Allegra CJ, Srinivasan A, Wang Y, Pogue-Geile KL, Lucas PC, Jacobs SA. Safety and Efficacy of T-DM1 Plus Neratinib in Patients With Metastatic HER2-Positive Breast Cancer: NSABP Foundation Trial FB-10. J Clin Oncol. 2019-10-10;37(29):2601-2609. doi: 10.1200/JCO.19.00858. PubMed PMID: 31442103; PMCID: PMC6784849.

Cao L, Basudan A, Sikora MJ, Bahreini A, Tasdemir N, Levine KM, Jankowitz RC, McAuliffe PF, Dabbs D, Haupt S, Haupt Y, Lucas PC, Lee AV, Oesterreich S, Atkinson JM. Frequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinoma. Cancer Lett. 2019-10-01;46121-30. doi: 10.1016/j.canlet.2019.06.011. PubMed PMID: 31229512; PMCID: PMC6682463.

Velez MA, Burns TF, Stabile LP. The estrogen pathway as a modulator of response to immunotherapy. Immunotherapy. 2019-09-01;11(13):1161-1176. doi: 10.2217/imt-2019-0024. PubMed PMID: 31361169.

Venier RE, Maurer LM, Kessler EM, Ranganathan S, McGough RL, Weiss KR, Malek MM, Meade J, Tersak JM, Bailey KM. A germline BARD1 mutation in a patient with Ewing Sarcoma: Implications for familial testing and counseling. Pediatr Blood Cancer. 2019-09-01;66(9):e27824. doi: 10.1002/pbc.27824. PubMed PMID: 31157509.

Koncar RF, Dey BR, Stanton AJ, Agrawal N, Wassell ML, McCarl LH, Locke AL, Sanders L, Morozova-Vaske O, Myers MI, Hamilton RL, Carcaboso AM, Kohanbash G, Hu B, Amankulor NM, Felker J, Kambhampati M, Nazarian J, Becher OJ, James CD, Hashizume R, Broniscer A, Pollack IF, Agnihotri S. Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas. Cancer Res. 2019-08-15;79(16):4026-4041. doi: 10.1158/0008-5472.CAN-18-3521. PubMed PMID: 31201162.

Saha AK, Mourad M, Kaplan MH, Chefetz I, Malek SN, Buckanovich R, Markovitz DM, Contreras-Galindo R. The Genomic Landscape of Centromeres in Cancers. Sci Rep. 2019-08-02;9(1):11259. doi: 10.1038/s41598-019-47757-6. PubMed PMID: 31375789; PMCID: PMC6677800.

Ward Rashidi MR, Mehta P, Bregenzer M, Raghavan S, Fleck EM, Horst EN, Harissa Z, Ravikumar V, Brady S, Bild A, Rao A, Buckanovich RJ, Mehta G. Engineered 3D Model of Cancer Stem Cell Enrichment and Chemoresistance. Neoplasia. 2019-08-01;21(8):822-836. doi: 10.1016/j.neo.2019.06.005. PubMed PMID: 31299607; PMCID: PMC6624324.

Li F, Pascal LE, Stolz DB, Wang K, Zhou Y, Chen W, Xu Y, Chen Y, Dhir R, Parwani AV, Nelson JB, DeFranco DB, Yoshimura N, Balasubramani GK, Gingrich JR, Maranchie JK, Jacobs BL, Davies BJ, Hrebinko RL, Bigley JD, McBride D, Guo P, He D, Wang Z. E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer. Prostate. 2019-08-01;79(11):1226-1237. doi: 10.1002/pros.23806. PubMed PMID: 31212363; PMCID: PMC6599563.

Pascal LE, Su F, Wang D, Ai J, Song Q, Wang Y, O'Malley KJ, Cross B, Rigatti LH, Green A, Dhir R, Wang Z. Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice. Neoplasia. 2019-08-01;21(8):752-764. doi: 10.1016/j.neo.2019.05.005. PubMed PMID: 31229879; PMCID: PMC6593215.

Newman WC, Amankulor NM. Neoadjuvant Anti-PD-1 Immunotherapy Leads to Survival Benefit in Recurrent Glioblastoma. Neurosurgery. 2019-08-01;85(2):E190-E191. doi: 10.1093/neuros/nyz174. PubMed PMID: 31304545.

Kim RS, Song N, Gavin PG, Salgado R, Bandos H, Kos Z, Floris G, Eynden GGGMVD, Badve S, Demaria S, Rastogi P, Fehrenbacher L, Mamounas EP, Swain SM, Wickerham DL, Costantino JP, Paik S, Wolmark N, Geyer CE, Lucas PC, Pogue-Geile KL. Stromal Tumor-infiltrating Lymphocytes in NRG Oncology/NSABP B-31 Adjuvant Trial for Early-Stage HER2-Positive Breast Cancer. J Natl Cancer Inst. 2019-08-01;111(8):867-871. doi: 10.1093/jnci/djz032. PubMed PMID: 30888406; PMCID: PMC6695304.

Gérard C, Di-Luoffo M, Gonay L, Caruso S, Couchy G, Loriot A, Castven D, Tao J, Konobrocka K, Cordi S, Monga SP, Hanert E, Marquardt JU, Zucman-Rossi J, Lemaigre FP. Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma. J Hepatol. 2019-08-01;71(2):323-332. doi: 10.1016/j.jhep.2019.03.024. PubMed PMID: 30953666.

Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A. β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma. Cancer Discov. 2019-08-01;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. PubMed PMID: 31186238; PMCID: PMC6677618.

Espinosa-Cotton M, Fertig EJ, Stabile LP, Gaither-Davis A, Bauman JE, Schmitz S, Gibson-Corley KN, Cheng Y, Jensen IJ, Badovinac VP, Laux D, Simons AL. A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab. Biomark Res. 2019-07-16;714. doi: 10.1186/s40364-019-0164-0. PubMed PMID: 31346466; PMCID: PMC6636109.

Mandel J, Wang H, Normolle DP, Chen W, Yan Q, Lucas PC, Benos PV, Prochownik EV. Expression patterns of small numbers of transcripts from functionally-related pathways predict survival in multiple cancers. BMC Cancer. 2019-07-12;19(1):686. doi: 10.1186/s12885-019-5851-6. PubMed PMID: 31299925; PMCID: PMC6626418.

Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019-07-11;4(13): doi: 10.1172/jci.insight.128217. PubMed PMID: 31292299; PMCID: PMC6629248.

Wang MT, Fer N, Galeas J, Collisson EA, Kim SE, Sharib J, McCormick F. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer. Nat Commun. 2019-07-11;10(1):3055. doi: 10.1038/s41467-019-11044-9. PubMed PMID: 31296870; PMCID: PMC6624260.

Chandler C, Liu T, Buckanovich R, Coffman LG. The double edge sword of fibrosis in cancer. Transl Res. 2019-07-01;20955-67. doi: 10.1016/j.trsl.2019.02.006. PubMed PMID: 30871956; PMCID: PMC6545239.

Cai C, Cooper GF, Lu KN, Ma X, Xu S, Zhao Z, Chen X, Xue Y, Lee AV, Clark N, Chen V, Lu S, Chen L, Yu L, Hochheiser HS, Jiang X, Wang QJ, Lu X. Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference. PLoS Comput Biol. 2019-07-01;15(7):e1007088. doi: 10.1371/journal.pcbi.1007088. PubMed PMID: 31276486; PMCID: PMC6650088.

Levine KM, Priedigkeit N, Basudan A, Tasdemir N, Sikora MJ, Sokol ES, Hartmaier RJ, Ding K, Ahmad NZ, Watters RJ, Weiss KR, Blohmer JU, Denkert C, Machleidt A, Karsten MM, Boisen MM, Elishaev E, Lucas PC, Lee AV, Oesterreich S. FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype. NPJ Breast Cancer. 2019-06-27;519. doi: 10.1038/s41523-019-0114-x. PubMed PMID: 31263748; PMCID: PMC6597581.

Wang H, Lu J, Dolezal J, Kulkarni S, Zhang W, Chen A, Gorka J, Mandel JA, Prochownik EV. Inhibition of hepatocellular carcinoma by metabolic normalization. PLoS One. 2019-06-26;14(6):e0218186. doi: 10.1371/journal.pone.0218186. PubMed PMID: 31242205; PMCID: PMC6594671.

Moulis M, Grousset E, Faccini J, Richetin K, Thomas G, Vindis C. The Multifunctional Sorting Protein PACS-2 Controls Mitophagosome Formation in Human Vascular Smooth Muscle Cells through Mitochondria-ER Contact Sites. Cells. 2019-06-25;8(6): doi: 10.3390/cells8060638. PubMed PMID: 31242668; PMCID: PMC6627983.

Rieunier G, Wu X, Macaulay VM, Lee AV, Weyer-Czernilofsky U, Bogenrieder T. Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis. Clin Cancer Res. 2019-06-15;25(12):3479-3485. doi: 10.1158/1078-0432.CCR-18-2697. PubMed PMID: 30745299.

Bossart EA, Tasdemir N, Sikora MJ, Bahreini A, Levine KM, Chen J, Basudan A, Jacobsen BM, Burns TF, Oesterreich S. SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma. Breast Cancer Res Treat. 2019-06-01;175(2):327-337. doi: 10.1007/s10549-019-05161-8. PubMed PMID: 30798422; PMCID: PMC6625318.

Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y. Novel gene regulatory networks identified in response to nitro-conjugated linoleic acid in human endothelial cells. Physiol Genomics. 2019-06-01;51(6):224-233. doi: 10.1152/physiolgenomics.00127.2018. PubMed PMID: 31074702; PMCID: PMC6620647.

Zatloukalova M, Mojovic M, Pavicevic A, Kabelac M, Freeman BA, Pekarova M, Vacek J. Redox properties and human serum albumin binding of nitro-oleic acid. Redox Biol. 2019-06-01;24101213. doi: 10.1016/j.redox.2019.101213. PubMed PMID: 31170679; PMCID: PMC6554544.

Ejaz A, Epperly MW, Hou W, Greenberger JS, Rubin JP. Adipose-Derived Stem Cell Therapy Ameliorates Ionizing Irradiation Fibrosis via Hepatocyte Growth Factor-Mediated Transforming Growth Factor-β Downregulation and Recruitment of Bone Marrow Cells. Stem Cells. 2019-06-01;37(6):791-802. doi: 10.1002/stem.3000. PubMed PMID: 30861238; PMCID: PMC8457883.

Singh M, Tian XJ, Donnenberg VS, Watson AM, Zhang J, Stabile LP, Watkins SC, Xing J, Sant S. Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration. Cancer Res. 2019-06-01;79(11):2962-2977. doi: 10.1158/0008-5472.CAN-18-3151. PubMed PMID: 30952634; PMCID: PMC6548579.

Jiang Y, Wells A, Sylakowski K, Clark AM, Ma B. Adult Stem Cell Functioning in the Tumor Micro-Environment. Int J Mol Sci. 2019-05-25;20(10): doi: 10.3390/ijms20102566. PubMed PMID: 31130595; PMCID: PMC6566759.

Bailey KM, Julian CM, Klinghoffer AN, Bernard H, Lucas PC, McAllister-Lucas LM. EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis. Oncotarget. 2019-05-21;10(36):3385-3399. doi: 10.18632/oncotarget.26939. PubMed PMID: 31164960; PMCID: PMC6534359.

Larsen MB, Perez Verdaguer M, Schmidt BF, Bruchez MP, Watkins SC, Sorkin A. Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis. Elife. 2019-05-08;8 doi: 10.7554/eLife.46135. PubMed PMID: 31066673; PMCID: PMC6533059.

Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP. Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. Cell Metab. 2019-05-07;29(5):1135-1150.e6. doi: 10.1016/j.cmet.2019.01.002. PubMed PMID: 30713111; PMCID: PMC6506359.

Brooker JE, Rubin JP, Marra KG. The Future of Facial Fat Grafting. J Craniofac Surg. 2019-05-01;30(3):644-651. doi: 10.1097/SCS.0000000000005274. PubMed PMID: 30817531.

Fourman MS, van Eck CF, Weiss KR, Goodman MA, McGough RL. Atypical Lipomatous Tumors: Does Our Inconsistent Terminology Have Patient Repercussions? Results of a Meta-Analysis. Am J Clin Oncol. 2019-05-01;42(5):487-492. doi: 10.1097/COC.0000000000000540. PubMed PMID: 30932920.

Shah AC, Komperda KW, Mavanur AA, Thorpe SW, Weiss KR, Goodman MA. Overall survival and tumor recurrence after surgical resection for primary malignant chest wall tumors: a single-center, single-surgeon experience. J Orthop Surg (Hong Kong). 2019-05-01;27(2):2309499019838296. doi: 10.1177/2309499019838296. PubMed PMID: 30939982.

Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, Rahman T, Chang LC, Kim S, Li J, Park Y, Song C, Oesterreich S, Sibille E, Tseng GC. MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis. Bioinformatics. 2019-05-01;35(9):1597-1599. doi: 10.1093/bioinformatics/bty825. PubMed PMID: 30304367; PMCID: PMC6499246.

Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP. β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis. Am J Pathol. 2019-05-01;189(5):1091-1104. doi: 10.1016/j.ajpath.2019.02.002. PubMed PMID: 30794807; PMCID: PMC6521893.

Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X. TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma. Am J Pathol. 2019-05-01;189(5):1077-1090. doi: 10.1016/j.ajpath.2019.01.016. PubMed PMID: 30794805; PMCID: PMC6526503.

Russell KL, Gorgulho CM, Allen A, Vakaki M, Wang Y, Facciabene A, Lee D, Roy P, Buchser WJ, Appleman LJ, Maranchie J, Storkus WJ, Lotze MT. Inhibiting Autophagy in Renal Cell Cancer and the Associated Tumor Endothelium. Cancer J. 2019-05-01;25(3):165-177. doi: 10.1097/PPO.0000000000000374. PubMed PMID: 31135523.

Gau D, Veon W, Shroff SG, Roy P. The VASP-profilin1 (Pfn1) interaction is critical for efficient cell migration and is regulated by cell-substrate adhesion in a PKA-dependent manner. J Biol Chem. 2019-04-26;294(17):6972-6985. doi: 10.1074/jbc.RA118.005255. PubMed PMID: 30814249; PMCID: PMC6497960.

Zhang R, Kikuchi AT, Nakao T, Russell JO, Preziosi ME, Poddar M, Singh S, Bell AW, England SG, Monga SP. Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury. Gene Expr. 2019-04-18;19(2):121-136. doi: 10.3727/105221618X15373858350141. PubMed PMID: 30236172; PMCID: PMC6466178.

Pradhan-Sundd T, Monga SP. Blood-Bile Barrier: Morphology, Regulation, and Pathophysiology. Gene Expr. 2019-04-18;19(2):69-87. doi: 10.3727/105221619X15469715711907. PubMed PMID: 30646969; PMCID: PMC6466181.

Wang H, Lu J, Kulkarni S, Zhang W, Gorka JE, Mandel JA, Goetzman ES, Prochownik EV. Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts. J Biol Chem. 2019-04-05;294(14):5466-5486. doi: 10.1074/jbc.RA118.005200. PubMed PMID: 30755479; PMCID: PMC6462518.

Jeffries EP, Di Filippo M, Galbiati F. Failure to reabsorb the primary cilium induces cellular senescence. FASEB J. 2019-04-01;33(4):4866-4882. doi: 10.1096/fj.201801382R. PubMed PMID: 30596512; PMCID: PMC6436649.

Funahashi Y, Takahashi R, Mizoguchi S, Suzuki T, Takaoka E, Ni J, Wang Z, DeFranco DB, de Groat WC, Tyagi P, Yoshimura N. Bladder overactivity and afferent hyperexcitability induced by prostate-to-bladder cross-sensitization in rats with prostatic inflammation. J Physiol. 2019-04-01;597(7):2063-2078. doi: 10.1113/JP277452. PubMed PMID: 30666643; PMCID: PMC6441933.

Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS. Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets. J Natl Cancer Inst. 2019-04-01;111(4):388-398. doi: 10.1093/jnci/djy110. PubMed PMID: 29961873; PMCID: PMC6449168.

Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, Yoon E, Lombard DB, Bild A, Mehta G, Romero I, Chiang CY, Landen C, Cravatt B, Hurley TD, Larsen SD, Buckanovich RJ. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019-03-12;26(11):3061-3075.e6. doi: 10.1016/j.celrep.2019.02.032. PubMed PMID: 30865894; PMCID: PMC7061440.

Jiang X, Wells A, Brufsky A, Neapolitan R. A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis. PLoS One. 2019-03-08;14(3):e0213292. doi: 10.1371/journal.pone.0213292. PubMed PMID: 30849111; PMCID: PMC6407919.

Zhang M, Yang D, Gold B. Origin of mutations in genes associated with human glioblastoma multiform cancer: random polymerase errors versus deamination. Heliyon. 2019-03-01;5(3):e01265. doi: 10.1016/j.heliyon.2019.e01265. PubMed PMID: 30899826; PMCID: PMC6407082.

Mahjoub A, Morales-Restrepo A, Fourman MS, Mandell JB, Feiqi L, Hankins ML, Watters RJ, Weiss KR. Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography Results in Negative Surgical Margins and Decreased Local Recurrence in an Orthotopic Mouse Model of Osteosarcoma. Ann Surg Oncol. 2019-03-01;26(3):894-898. doi: 10.1245/s10434-018-07114-9. PubMed PMID: 30588559; PMCID: PMC6373227.

Jiang A, Okabe H, Popovic B, Preziosi ME, Pradhan-Sundd T, Poddar M, Singh S, Bell A, England SG, Nagarajan S, Monga SP. Loss of Wnt Secretion by Macrophages Promotes Hepatobiliary Injury after Administration of 3,5-Diethoxycarbonyl-1, 4-Dihydrocollidine Diet. Am J Pathol. 2019-03-01;189(3):590-603. doi: 10.1016/j.ajpath.2018.11.010. PubMed PMID: 30610845; PMCID: PMC6436111.

Molina L, Yang H, Adebayo Michael AO, Oertel M, Bell A, Singh S, Chen X, Tao J, Monga SPS. mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development. Oncotarget. 2019-02-19;10(15):1475-1490. doi: 10.18632/oncotarget.26668. PubMed PMID: 30863496; PMCID: PMC6407673.

Surve SV, Myers PJ, Clayton SA, Watkins SC, Lazzara MJ, Sorkin A. Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells. Mol Biol Cell. 2019-02-15;30(4):506-523. doi: 10.1091/mbc.E18-08-0512. PubMed PMID: 30586319; PMCID: PMC6594441.

Smith NG, Gyanchandani R, Shah OS, Gurda GT, Lucas PC, Hartmaier RJ, Brufsky AM, Puhalla S, Bahreini A, Kota K, Wald AI, Nikiforov YE, Nikiforova MN, Oesterreich S, Lee AV. Targeted mutation detection in breast cancer using MammaSeq™. Breast Cancer Res. 2019-02-08;21(1):22. doi: 10.1186/s13058-019-1102-7. PubMed PMID: 30736836; PMCID: PMC6368740.

Jobbagy S, Vitturi DA, Salvatore SR, Turell L, Pires MF, Kansanen E, Batthyany C, Lancaster JR Jr, Freeman BA, Schopfer FJ. Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis. Redox Biol. 2019-02-01;21101050. doi: 10.1016/j.redox.2018.11.008. PubMed PMID: 30654300; PMCID: PMC6348771.

Coffman LG, Pearson AT, Frisbie LG, Freeman Z, Christie E, Bowtell DD, Buckanovich RJ. Ovarian Carcinoma-Associated Mesenchymal Stem Cells Arise from Tissue-Specific Normal Stroma. Stem Cells. 2019-02-01;37(2):257-269. doi: 10.1002/stem.2932. PubMed PMID: 30353617; PMCID: PMC6392140.

McLean K, Tan L, Bolland DE, Coffman LG, Peterson LF, Talpaz M, Neamati N, Buckanovich RJ. Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth. Oncogene. 2019-02-01;38(9):1576-1584. doi: 10.1038/s41388-018-0523-6. PubMed PMID: 30305729; PMCID: PMC6374186.

Russell JO, Lu WY, Okabe H, Abrams M, Oertel M, Poddar M, Singh S, Forbes SJ, Monga SP. Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes. Hepatology. 2019-02-01;69(2):742-759. doi: 10.1002/hep.30270. PubMed PMID: 30215850; PMCID: PMC6351199.

Ruffalo M, Thomas R, Chen J, Lee AV, Oesterreich S, Bar-Joseph Z. Network-guided prediction of aromatase inhibitor response in breast cancer. PLoS Comput Biol. 2019-02-01;15(2):e1006730. doi: 10.1371/journal.pcbi.1006730. PubMed PMID: 30742607; PMCID: PMC6386390.

Monga SP. Updates on hepatic homeostasis and the many tiers of hepatobiliary repair. Nat Rev Gastroenterol Hepatol. 2019-02-01;16(2):84-86. doi: 10.1038/s41575-018-0090-x. PubMed PMID: 30531815; PMCID: PMC8062871.

Basudan A, Priedigkeit N, Hartmaier RJ, Sokol ES, Bahreini A, Watters RJ, Boisen MM, Bhargava R, Weiss KR, Karsten MM, Denkert C, Blohmer JU, Leone JP, Hamilton RL, Brufsky AM, Elishaev E, Lucas PC, Lee AV, Oesterreich S. Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer. Mol Cancer Res. 2019-02-01;17(2):457-468. doi: 10.1158/1541-7786.MCR-18-0946. PubMed PMID: 30355675; PMCID: PMC6359977.

Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA. Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells. J Biol Chem. 2019-01-11;294(2):397-404. doi: 10.1074/jbc.AC118.005899. PubMed PMID: 30478172; PMCID: PMC6333886.

Belur Nagaraj A, Joseph P, Ponting E, Fedorov Y, Singh S, Cole A, Lee W, Yoon E, Baccarini A, Scacheri P, Buckanovich R, Adams DJ, Drapkin R, Brown BD, DiFeo A. A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs. Stem Cell Reports. 2019-01-08;12(1):122-134. doi: 10.1016/j.stemcr.2018.12.002. PubMed PMID: 30629937; PMCID: PMC6335585.

Chen Y, Sun J, Huang Y, Liu Y, Liang L, Yang D, Lu B, Li S. Targeted codelivery of doxorubicin and IL-36γ expression plasmid for an optimal chemo-gene combination therapy against cancer lung metastasis. Nanomedicine. 2019-01-01;15(1):129-141. doi: 10.1016/j.nano.2018.09.005. PubMed PMID: 30308300; PMCID: PMC6289619.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K. Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury. J Hepatol. 2019-01-01;70(1):108-117. doi: 10.1016/j.jhep.2018.09.023. PubMed PMID: 30287339; PMCID: PMC6459193.

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng HL, Monga SP, Shin D. Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8. Gastroenterology. 2019-01-01;156(1):187-202.e14. doi: 10.1053/j.gastro.2018.09.039. PubMed PMID: 30267710; PMCID: PMC6309465.

Madariaga A, Rustin GJS, Buckanovich RJ, Trent JC, Oza AM. Wanna Get Away? Maintenance Treatments and Chemotherapy Holidays in Gynecologic Cancers. Am Soc Clin Oncol Educ Book. 2019-01-01;39e152-e166. doi: 10.1200/EDBK_238755. PubMed PMID: 31099646.

Dong J, Wu Z, Wang D, Pascal LE, Nelson JB, Wipf P, Wang Z. Hsp70 Binds to the Androgen Receptor N-terminal Domain and Modulates the Receptor Function in Prostate Cancer Cells. Mol Cancer Ther. 2019-01-01;18(1):39-50. doi: 10.1158/1535-7163.MCT-18-0432. PubMed PMID: 30297360; PMCID: PMC6318070.

Qin Y, Vasilatos SN, Chen L, Wu H, Cao Z, Fu Y, Huang M, Vlad AM, Lu B, Oesterreich S, Davidson NE, Huang Y. Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade. Oncogene. 2019-01-01;38(3):390-405. doi: 10.1038/s41388-018-0451-5. PubMed PMID: 30111819; PMCID: PMC6336685.

Silva MMA, Kokai LE, Donnenberg VS, Fine JL, Marra KG, Donnenberg AD, Neto MS, Rubin JP. Oncologic Safety of Fat Grafting for Autologous Breast Reconstruction in an Animal Model of Residual Breast Cancer. Plast Reconstr Surg. 2019-01-01;143(1):103-112. doi: 10.1097/PRS.0000000000005085. PubMed PMID: 30589782; PMCID: PMC8462977.

Yochum ZA, Cades J, Wang H, Chatterjee S, Simons BW, O'Brien JP, Khetarpal SK, Lemtiri-Chlieh G, Myers KV, Huang EH, Rudin CM, Tran PT, Burns TF. Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer. Oncogene. 2019-01-01;38(5):656-670. doi: 10.1038/s41388-018-0482-y. PubMed PMID: 30171258; PMCID: PMC6358506.

Linkov F, Silverstein JC, Davis M, Crocker B, Hao D, Schneider A, Schwenk M, Winters S, Zelnis J, Lee AV, Becich MJ. Integration of Cancer Registry Data into the Text Information Extraction System: Leveraging the Structured Data Import Tool. J Pathol Inform. 2018-12-24;947. doi: 10.4103/jpi.jpi_38_18. PubMed PMID: 30662793; PMCID: PMC6319041.

Zhong M, Pascal LE, Cheng E, Masoodi KZ, Chen W, Green A, Cross BW, Parrinello E, Rigatti LH, Wang Z. Concurrent EAF2 and ELL2 loss phenocopies individual EAF2 or ELL2 loss in prostate cancer cells and murine prostate. Am J Clin Exp Urol. 2018-12-20;6(6):234-244. PubMed PMID: 30697579; PMCID: PMC6334201.

Krzysiak TC, Thomas L, Choi YJ, Auclair S, Qian Y, Luan S, Krasnow SM, Thomas LL, Koharudin LMI, Benos PV, Marks DL, Gronenborn AM, Thomas G. An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity. Mol Cell. 2018-12-20;72(6):985-998.e7. doi: 10.1016/j.molcel.2018.10.007. PubMed PMID: 30415949; PMCID: PMC6309500.

Andersen CL, Boisen MM, Sikora MJ, Ma T, Tseng G, Suryawanshi S, Vlad A, Elishaev E, Edwards RP, Oesterreich S. The Evolution of Estrogen Receptor Signaling in the Progression of Endometriosis to Endometriosis-Associated Ovarian Cancer. Horm Cancer. 2018-12-01;9(6):399-407. doi: 10.1007/s12672-018-0350-9. PubMed PMID: 30302736.

Wells A, Clark A, Bradshaw A, Ma B, Edington H. The great escape: How metastases of melanoma, and other carcinomas, avoid elimination. Exp Biol Med (Maywood). 2018-12-01;243(17-18):1245-1255. doi: 10.1177/1535370218820287. PubMed PMID: 30764707; PMCID: PMC6348591.

Gyanchandani R, Kvam E, Heller R, Finehout E, Smith N, Kota K, Nelson JR, Griffin W, Puhalla S, Brufsky AM, Davidson NE, Lee AV. Whole genome amplification of cell-free DNA enables detection of circulating tumor DNA mutations from fingerstick capillary blood. Sci Rep. 2018-11-23;8(1):17313. doi: 10.1038/s41598-018-35470-9. PubMed PMID: 30470782; PMCID: PMC6251935.

Beckwitt CH, Brufsky A, Oltvai ZN, Wells A. Statin drugs to reduce breast cancer recurrence and mortality. Breast Cancer Res. 2018-11-20;20(1):144. doi: 10.1186/s13058-018-1066-z. PubMed PMID: 30458856; PMCID: PMC6247616.

Phua YL, Clugston A, Chen KH, Kostka D, Ho J. Small non-coding RNA expression in mouse nephrogenic mesenchymal progenitors. Sci Data. 2018-11-13;5180218. doi: 10.1038/sdata.2018.218. PubMed PMID: 30422124; PMCID: PMC6233257.

Qiao Y, Xu M, Tao J, Che L, Cigliano A, Monga SP, Calvisi DF, Chen X. Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice. BMC Cancer. 2018-11-12;18(1):1093. doi: 10.1186/s12885-018-4870-z. PubMed PMID: 30419856; PMCID: PMC6233269.

Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, Lin H, Stabile LP, Watowich SS, Kadara H, Moghaddam SJ. Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer. Nat Commun. 2018-11-02;9(1):4589. doi: 10.1038/s41467-018-07042-y. PubMed PMID: 30389925; PMCID: PMC6214980.

Haskett DG, Saleh KS, Lorentz KL, Josowitz AD, Luketich SK, Weinbaum JS, Kokai LE, D'Amore A, Marra KG, Rubin JP, Wagner WR, Vorp DA. An exploratory study on the preparation and evaluation of a "same-day" adipose stem cell-based tissue-engineered vascular graft. J Thorac Cardiovasc Surg. 2018-11-01;156(5):1814-1822.e3. doi: 10.1016/j.jtcvs.2018.05.120. PubMed PMID: 30057192; PMCID: PMC6200342.

Tasdemir N, Bossart EA, Li Z, Zhu L, Sikora MJ, Levine KM, Jacobsen BM, Tseng GC, Davidson NE, Oesterreich S. Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures. Cancer Res. 2018-11-01;78(21):6209-6222. doi: 10.1158/0008-5472.CAN-18-1416. PubMed PMID: 30228172; PMCID: PMC6507416.

Mattu S, Saliba C, Sulas P, Zavattari P, Perra A, Kowalik MA, Monga SP, Columbano A. High Frequency of β-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. Am J Pathol. 2018-11-01;188(11):2497-2507. doi: 10.1016/j.ajpath.2018.07.022. PubMed PMID: 30201494.

Yang T, Jing Y, Dong J, Yu X, Zhong M, Pascal LE, Wang D, Zhang Z, Qiao B, Wang Z. Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells. Prostate. 2018-11-01;78(15):1201-1212. doi: 10.1002/pros.23695. PubMed PMID: 30009504; PMCID: PMC6537586.

Bourne DA, Thomas RD, Bliley J, Haas G, Wyse A, Donnenberg A, Donnenberg VS, Chow I, Cooper R, Coleman S, Marra K, Pasquina PF, Rubin JP. Amputation-Site Soft-Tissue Restoration Using Adipose Stem Cell Therapy. Plast Reconstr Surg. 2018-11-01;142(5):1349-1352. doi: 10.1097/PRS.0000000000004889. PubMed PMID: 30511990.

Xu J, Zhao W, Sun J, Huang Y, Wang P, Venkataramanan R, Yang D, Ma X, Rana A, Li S. Novel glucosylceramide synthase inhibitor based prodrug copolymer micelles for delivery of anticancer agents. J Control Release. 2018-10-28;288212-226. doi: 10.1016/j.jconrel.2018.09.011. PubMed PMID: 30223045; PMCID: PMC6177216.

Wells A, Wiley HS. A systems perspective of heterocellular signaling. Essays Biochem. 2018-10-26;62(4):607-617. doi: 10.1042/EBC20180015. PubMed PMID: 30139877; PMCID: PMC6309864.

Guan X, Luo L, Begum G, Kohanbash G, Song Q, Rao A, Amankulor N, Sun B, Sun D, Jia W. Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas. J Exp Clin Cancer Res. 2018-10-17;37(1):255. doi: 10.1186/s13046-018-0923-z. PubMed PMID: 30333031; PMCID: PMC6192309.

Gu L, Zhu Y, Lin X, Li Y, Cui K, Prochownik EV, Li Y. Amplification of Glyceronephosphate O-Acyltransferase and Recruitment of USP30 Stabilize DRP1 to Promote Hepatocarcinogenesis. Cancer Res. 2018-10-15;78(20):5808-5819. doi: 10.1158/0008-5472.CAN-18-0340. PubMed PMID: 30143522.

Nagle AM, Levine KM, Tasdemir N, Scott JA, Burlbaugh K, Kehm J, Katz TA, Boone DN, Jacobsen BM, Atkinson JM, Oesterreich S, Lee AV. Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors. Clin Cancer Res. 2018-10-15;24(20):5165-5177. doi: 10.1158/1078-0432.CCR-18-0279. PubMed PMID: 29941485; PMCID: PMC6821389.

Chu Y, Lee S, Shah T, Yin C, Barth M, Miles RR, Ayello J, Morris E, Harrison L, Van de Ven C, Galardy P, Goldman SC, Lim MS, Hermiston M, McAllister-Lucas LM, Giulino-Roth L, Perkins SL, Cairo MS. Ibrutinib significantly inhibited Bruton's tyrosine kinase (BTK) phosphorylation,in-vitro proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model. Oncoimmunology. 2018-10-11;8(1):e1512455. doi: 10.1080/2162402X.2018.1512455. PubMed PMID: 30546948; PMCID: PMC6287791.

Gau D, Roy P. SRF'ing and SAP'ing - the role of MRTF proteins in cell migration. J Cell Sci. 2018-10-11;131(19): doi: 10.1242/jcs.218222. PubMed PMID: 30309957; PMCID: PMC6919568.

Amatya N, Childs EE, Cruz JA, Aggor FEY, Garg AV, Berman AJ, Gudjonsson JE, Atasoy U, Gaffen SL. IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a. Sci Signal. 2018-10-09;11(551): doi: 10.1126/scisignal.aat4617. PubMed PMID: 30301788; PMCID: PMC6188668.

Yoon JH, Nouraie M, Chen X, Zou RH, Sellares J, Veraldi KL, Chiarchiaro J, Lindell K, Wilson DO, Kaminski N, Burns T, Trejo Bittar H, Yousem S, Gibson K, Kass DJ. Characteristics of lung cancer among patients with idiopathic pulmonary fibrosis and interstitial lung disease - analysis of institutional and population data. Respir Res. 2018-10-03;19(1):195. doi: 10.1186/s12931-018-0899-4. PubMed PMID: 30285867; PMCID: PMC6171146.

Chakraborty S, Jiang C, Gau D, Oddo M, Ding Z, Vollmer L, Joy M, Schiemann W, Stolz DB, Vogt A, Ghosh S, Roy P. Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells. Br J Cancer. 2018-10-01;119(9):1106-1117. doi: 10.1038/s41416-018-0284-6. PubMed PMID: 30318519; PMCID: PMC6219497.

Pradhan-Sundd T, Vats R, Russell JO, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P. Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice. Gastroenterology. 2018-10-01;155(4):1218-1232.e24. doi: 10.1053/j.gastro.2018.06.048. PubMed PMID: 29964040; PMCID: PMC6174089.

Beckwitt CH, Clark AM, Ma B, Whaley D, Oltvai ZN, Wells A. Statins attenuate outgrowth of breast cancer metastases. Br J Cancer. 2018-10-01;119(9):1094-1105. doi: 10.1038/s41416-018-0267-7. PubMed PMID: 30401978; PMCID: PMC6220112.

Wang H, Dolezal JM, Kulkarni S, Lu J, Mandel J, Jackson LE, Alencastro F, Duncan AW, Prochownik EV. Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice. J Biol Chem. 2018-09-21;293(38):14740-14757. doi: 10.1074/jbc.RA118.004099. PubMed PMID: 30087120; PMCID: PMC6153302.

Cao C, Wu H, Vasilatos SN, Chandran U, Qin Y, Wan Y, Oesterreich S, Davidson NE, Huang Y. HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells. Int J Cancer. 2018-09-15;143(6):1388-1401. doi: 10.1002/ijc.31419. PubMed PMID: 29633255; PMCID: PMC6105499.

Du T, Sikora MJ, Levine KM, Tasdemir N, Riggins RB, Wendell SG, Van Houten B, Oesterreich S. Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer. Breast Cancer Res. 2018-09-04;20(1):106. doi: 10.1186/s13058-018-1041-8. PubMed PMID: 30180878; PMCID: PMC6124012.

Garon EB, Siegfried JM, Stabile LP, Young PA, Marquez-Garban DC, Park DJ, Patel R, Hu EH, Sadeghi S, Parikh RJ, Reckamp KL, Adams B, Elashoff RM, Elashoff D, Grogan T, Wang HJ, Dacic S, Brennan M, Valdes Y, Davenport S, Dubinett SM, Press MF, Slamon DJ, Pietras RJ. Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer. Lung Cancer. 2018-09-01;12391-98. doi: 10.1016/j.lungcan.2018.06.013. PubMed PMID: 30089602; PMCID: PMC6118115.

Fonseca BD, Lahr RM, Damgaard CK, Alain T, Berman AJ. LARP1 on TOP of ribosome production. Wiley Interdiscip Rev RNA. 2018-09-01;9(5):e1480. doi: 10.1002/wrna.1480. PubMed PMID: 29722158; PMCID: PMC6214789.

Linkov F, Goughnour SL, Adambekov S, Lokshin A, Kelley JL, Sukumvanich P, Comerci JT, Marra KG, Kokai LE, Rubin JP, Vlad AM, Philips BJ, Edwards RP. Inflammatory biomarker in adipose stem cells of women with endometrial cancer. Biomark Med. 2018-09-01;12(9):945-952. doi: 10.2217/bmm-2017-0355. PubMed PMID: 30043637; PMCID: PMC6439519.

Bi Y, Jiang M, Guo W, Guan X, Xu M, Ren S, Yang D, Gaikwad NW, Selcer KW, Xie W. Sex-Dimorphic and Sex Hormone-Dependent Role of Steroid Sulfatase in Adipose Inflammation and Energy Homeostasis. Endocrinology. 2018-09-01;159(9):3365-3377. doi: 10.1210/en.2018-00531. PubMed PMID: 30060148; PMCID: PMC6112598.

Rodriguez-Duarte J, Dapueto R, Galliussi G, Turell L, Kamaid A, Khoo NKH, Schopfer FJ, Freeman BA, Escande C, Batthyány C, Ferrer-Sueta G, López GV. Electrophilic nitroalkene-tocopherol derivatives: synthesis, physicochemical characterization and evaluation of anti-inflammatory signaling responses. Sci Rep. 2018-08-24;8(1):12784. doi: 10.1038/s41598-018-31218-7. PubMed PMID: 30143727; PMCID: PMC6109136.

Preziosi M, Poddar M, Singh S, Monga SP. Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer. Gene Expr. 2018-08-22;18(3):209-219. doi: 10.3727/105221618X15205148413587. PubMed PMID: 29519268; PMCID: PMC6190118.

Pal R, Wei N, Song N, Wu S, Kim RS, Wang Y, Gavin PG, Lucas PC, Srinivasan A, Allegra CJ, Jacobs SA, Paik S, Schmitz JC, Pogue-Geile KL. Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations. PLoS One. 2018-08-17;13(8):e0200836. doi: 10.1371/journal.pone.0200836. PubMed PMID: 30118499; PMCID: PMC6097647.

McAuley JR, Freeman TJ, Ekambaram P, Lucas PC, McAllister-Lucas LM. CARMA3 Is a Critical Mediator of G Protein-Coupled Receptor and Receptor Tyrosine Kinase-Driven Solid Tumor Pathogenesis. Front Immunol. 2018-08-15;91887. doi: 10.3389/fimmu.2018.01887. PubMed PMID: 30158935; PMCID: PMC6104486.

Wang Y, Wang Z, Xu J, Li J, Li S, Zhang M, Yang D. Systematic identification of non-coding pharmacogenomic landscape in cancer. Nat Commun. 2018-08-09;9(1):3192. doi: 10.1038/s41467-018-05495-9. PubMed PMID: 30093685; PMCID: PMC6085336.

Chakraborty PK, Murphy B, Mustafi SB, Dey A, Xiong X, Rao G, Naz S, Zhang M, Yang D, Dhanasekaran DN, Bhattacharya R, Mukherjee P. Cystathionine β-synthase regulates mitochondrial morphogenesis in ovarian cancer. FASEB J. 2018-08-01;32(8):4145-4157. doi: 10.1096/fj.201701095R. PubMed PMID: 29494264; PMCID: PMC6044063.

Kurland BF, Oesterreich S. Heterogeneity in Metastatic Breast Cancer (18)F-Fluoroestradiol Uptake: Clinically Actionable, Biologically Illuminating? J Nucl Med. 2018-08-01;59(8):1210-1211. doi: 10.2967/jnumed.118.214304. PubMed PMID: 29903931; PMCID: PMC6071507.

Zamora PF, Hu L, Knowlton JJ, Lahr RM, Moreno RA, Berman AJ, Prasad BVV, Dermody TS. Reovirus Nonstructural Protein σNS Acts as an RNA Stability Factor Promoting Viral Genome Replication. J Virol. 2018-08-01;92(15): doi: 10.1128/JVI.00563-18. PubMed PMID: 29769334; PMCID: PMC6052290.

Stanley K, Friehling E, Ranganathan S, Mazariegos G, McAllister-Lucas LM, Sindhi R. Post-transplant lymphoproliferative disorder in pediatric intestinal transplant recipients: A literature review. Pediatr Transplant. 2018-08-01;22(5):e13211. doi: 10.1111/petr.13211. PubMed PMID: 29745058.

Kalash R, Glaser SM, Flickinger JC, Burton S, Heron DE, Gerszten PC, Engh JA, Amankulor NM, Vargo JA. Stereotactic body radiation therapy for benign spine tumors: is dose de-escalation appropriate? J Neurosurg Spine. 2018-08-01;29(2):220-225. doi: 10.3171/2017.12.SPINE17920. PubMed PMID: 29799334; PMCID: PMC7425586.

Gogineni E, Vargo JA, Glaser SM, Flickinger JC, Burton SA, Engh JA, Amankulor NM, Beriwal S, Quinn AE, Ozhasoglu C, Heron DE. Long-Term Survivorship Following Stereotactic Radiosurgery Alone for Brain Metastases: Risk of Intracranial Failure and Implications for Surveillance and Counseling. Neurosurgery. 2018-08-01;83(2):203-209. doi: 10.1093/neuros/nyx376. PubMed PMID: 28945873; PMCID: PMC7448674.

Preziosi M, Monga SP. Novel Genetic Activation Screening in Liver Repopulation and Cancer: Now CRISPR Than Ever! Hepatology. 2018-08-01;68(2):408-411. doi: 10.1002/hep.30084. PubMed PMID: 29742805; PMCID: PMC6097894.

Li G, Martínez-Bonet M, Wu D, Yang Y, Cui J, Nguyen HN, Cunin P, Levescot A, Bai M, Westra HJ, Okada Y, Brenner MB, Raychaudhuri S, Hendrickson EA, Maas RL, Nigrovic PA. High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Nat Genet. 2018-08-01;50(8):1180-1188. doi: 10.1038/s41588-018-0159-z. PubMed PMID: 30013183; PMCID: PMC6072570.

Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga SP. Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma. Am J Pathol. 2018-08-01;188(8):1895-1909. doi: 10.1016/j.ajpath.2018.05.006. PubMed PMID: 29920228; PMCID: PMC6099390.

Waldner M, Zhang W, James IB, Allbright K, Havis E, Bliley JM, Almadori A, Schweizer R, Plock JA, Washington KM, Gorantla VS, Solari MG, Marra KG, Rubin JP. Characteristics and Immunomodulating Functions of Adipose-Derived and Bone Marrow-Derived Mesenchymal Stem Cells Across Defined Human Leukocyte Antigen Barriers. Front Immunol. 2018-07-24;91642. doi: 10.3389/fimmu.2018.01642. PubMed PMID: 30087676; PMCID: PMC6066508.

Gu Y, Wang R, Han Y, Zhou W, Zhao Z, Chen T, Zhang Y, Peng F, Liang H, Qi L, Zhao W, Yang D, Guo Z. A landscape of synthetic viable interactions in cancer. Brief Bioinform. 2018-07-20;19(4):644-655. doi: 10.1093/bib/bbw142. PubMed PMID: 28096076.

Crasto JA, Fourman MS, Morales-Restrepo A, Mahjoub A, Mandell JB, Ramnath K, Tebbets JC, Watters RJ, Weiss KR. Disulfiram reduces metastatic osteosarcoma tumor burden in an immunocompetent Balb/c or-thotopic mouse model. Oncotarget. 2018-07-10;9(53):30163-30172. doi: 10.18632/oncotarget.25733. PubMed PMID: 30046395; PMCID: PMC6059028.

Zhang M, Yang D, Gold B. The Adenomatous Polyposis Coli (APC) mutation spectra in different anatomical regions of the large intestine in colorectal cancer. Mutat Res. 2018-07-01;8101-5. doi: 10.1016/j.mrfmmm.2018.04.003. PubMed PMID: 29751128.

Ling DC, Flickinger JC, Burton SA, Heron DE, Quinn AE, Bejjani GK, Engh JA, Gerszten PC, Amankulor NM, Vargo JA. Long-Term Outcomes After Stereotactic Radiosurgery for Spine Metastases: Radiation Dose-Response for Late Toxicity. Int J Radiat Oncol Biol Phys. 2018-07-01;101(3):602-609. doi: 10.1016/j.ijrobp.2018.02.035. PubMed PMID: 29678526; PMCID: PMC7453968.

Pouyan MB, Kostka D. Random forest based similarity learning for single cell RNA sequencing data. Bioinformatics. 2018-07-01;34(13):i79-i88. doi: 10.1093/bioinformatics/bty260. PubMed PMID: 29950006; PMCID: PMC6022547.

Preziosi M, Okabe H, Poddar M, Singh S, Monga SP. Endothelial Wnts regulate β-catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt-Wnt situation. Hepatol Commun. 2018-07-01;2(7):845-860. doi: 10.1002/hep4.1196. PubMed PMID: 30027142; PMCID: PMC6049069.

Oesterreich S, Lucas PC, McAuliffe PF, Bruno TC, Vignali DAA. Opening the Door for Immune Oncology Studies in Invasive Lobular Breast Cancer. J Natl Cancer Inst. 2018-07-01;110(7):696-698. doi: 10.1093/jnci/djy014. PubMed PMID: 29471462.

Freeman BA, O'Donnell VB, Schopfer FJ. The discovery of nitro-fatty acids as products of metabolic and inflammatory reactions and mediators of adaptive cell signaling. Nitric Oxide. 2018-07-01;77106-111. doi: 10.1016/j.niox.2018.05.002. PubMed PMID: 29742447; PMCID: PMC5983901.

Ishikawa T, Hosaka YZ, Beckwitt C, Wells A, Oltvai ZN, Warita K. Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics. Oncotarget. 2018-06-29;9(50):29304-29315. doi: 10.18632/oncotarget.25448. PubMed PMID: 30034619; PMCID: PMC6047681.

Yoneyama T, Gorry M, Sobo-Vujanovic A, Lin Y, Vujanovic L, Gaither-Davis A, Moss ML, Miller MA, Griffith LG, Lauffenburger DA, Stabile LP, Herman J, Vujanovic NL. ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker. J Cancer. 2018-06-23;9(14):2559-2570. doi: 10.7150/jca.24601. PubMed PMID: 30026855; PMCID: PMC6036891.

Kveiborg M, Thomas G. PACS-2 functions in colorectal cancer. Aging (Albany NY). 2018-06-22;10(6):1190-1191. doi: 10.18632/aging.101489. PubMed PMID: 29936496; PMCID: PMC6046226.

Jamwal G, Singh G, Dar MS, Singh P, Bano N, Syed SH, Sandhu P, Akhter Y, Monga SP, Dar MJ. Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways. Biochim Biophys Acta Mol Cell Res. 2018-06-01;1865(6):920-931. doi: 10.1016/j.bbamcr.2018.03.013. PubMed PMID: 29621572.

Russell JO, Ko S, Saggi HS, Singh S, Poddar M, Shin D, Monga SP. Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration. Am J Pathol. 2018-06-01;188(6):1389-1405. doi: 10.1016/j.ajpath.2018.02.006. PubMed PMID: 29545201; PMCID: PMC5971221.

Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP. Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis. Hepatology. 2018-06-01;67(6):2320-2337. doi: 10.1002/hep.29585. PubMed PMID: 29023813; PMCID: PMC5893443.

Bradshaw A, Sylakowski K, Wells A. The Pro-reparative Engine: Stem Cells Aid Healing by Dampening Inflammation. Curr Pathobiol Rep. 2018-06-01;6(2):109-115. doi: 10.1007/s40139-018-0167-9. PubMed PMID: 30271682; PMCID: PMC6157924.

Luthra S, Chandran U, Diergaarde B, Becich M, Lee AV, Neumann CA. Expression of reactive species related genes is associated with patient survival in luminal B breast cancer. Free Radic Biol Med. 2018-05-20;120170-180. doi: 10.1016/j.freeradbiomed.2018.03.011. PubMed PMID: 29545070; PMCID: PMC5940524.

Zhan N, Michael AA, Wu K, Zeng G, Bell A, Tao J, Monga SP. The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model. Gene Expr. 2018-05-18;18(2):135-147. doi: 10.3727/105221618X15174108894682. PubMed PMID: 29409568; PMCID: PMC5954626.

Zeng Z, Jiang X, Li X, Wells A, Luo Y, Neapolitan R. Conjugated equine estrogen and medroxyprogesterone acetate are associated with decreased risk of breast cancer relative to bioidentical hormone therapy and controls. PLoS One. 2018-05-16;13(5):e0197064. doi: 10.1371/journal.pone.0197064. PubMed PMID: 29768475; PMCID: PMC5955567.

Beckwitt CH, Shiraha K, Wells A. Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling. PLoS One. 2018-05-15;13(5):e0197422. doi: 10.1371/journal.pone.0197422. PubMed PMID: 29763460; PMCID: PMC5953490.

Du T, Zhu L, Levine KM, Tasdemir N, Lee AV, Vignali DAA, Houten BV, Tseng GC, Oesterreich S. Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism. Sci Rep. 2018-05-08;8(1):7205. doi: 10.1038/s41598-018-25357-0. PubMed PMID: 29739984; PMCID: PMC5940770.

Nasrazadani A, Thomas RA, Oesterreich S, Lee AV. Precision Medicine in Hormone Receptor-Positive Breast Cancer. Front Oncol. 2018-05-04;8144. doi: 10.3389/fonc.2018.00144. PubMed PMID: 29780747; PMCID: PMC5945817.

Li W, Cui K, Prochownik EV, Li Y. The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth. Cell Death Dis. 2018-05-01;9(5):482. doi: 10.1038/s41419-018-0523-z. PubMed PMID: 29706623; PMCID: PMC5924753.

Villacorta L, Minarrieta L, Salvatore SR, Khoo NK, Rom O, Gao Z, Berman RC, Jobbagy S, Li L, Woodcock SR, Chen YE, Freeman BA, Ferreira AM, Schopfer FJ, Vitturi DA. In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation. Redox Biol. 2018-05-01;15522-531. doi: 10.1016/j.redox.2018.01.005. PubMed PMID: 29413964; PMCID: PMC5881417.

Goetzman ES, Prochownik EV. The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues. Front Endocrinol (Lausanne). 2018-04-12;9129. doi: 10.3389/fendo.2018.00129. PubMed PMID: 29706933; PMCID: PMC5907532.

Müller S, Agnihotri S, Shoger KE, Myers MI, Smith N, Chaparala S, Villanueva CR, Chattopadhyay A, Lee AV, Butterfield LH, Diaz A, Okada H, Pollack IF, Kohanbash G. Peptide vaccine immunotherapy biomarkers and response patterns in pediatric gliomas. JCI Insight. 2018-04-05;3(7): doi: 10.1172/jci.insight.98791. PubMed PMID: 29618666; PMCID: PMC5928860.

Pascal LE, Wang Y, Zhong M, Wang D, Chakka AB, Yang Z, Li F, Song Q, Rigatti LH, Chaparala S, Chandran U, Parwani AV, Wang Z. EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer. Neoplasia. 2018-04-01;20(4):351-363. doi: 10.1016/j.neo.2018.01.011. PubMed PMID: 29518696; PMCID: PMC5909677.

Clark AM, Kumar MP, Wheeler SE, Young CL, Venkataramanan R, Stolz DB, Griffith LG, Lauffenburger DA, Wells A. A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures. Mol Cell Proteomics. 2018-04-01;17(4):619-630. doi: 10.1074/mcp.RA117.000370. PubMed PMID: 29353230; PMCID: PMC5880110.

Li S, Chang Z, Zhu T, Villacorta L, Li Y, Freeman BA, Chen YE, Zhang J. Transcriptomic sequencing reveals diverse adaptive gene expression responses of human vascular smooth muscle cells to nitro-conjugated linoleic acid. Physiol Genomics. 2018-04-01;50(4):287-295. doi: 10.1152/physiolgenomics.00090.2017. PubMed PMID: 29473818; PMCID: PMC5966802.

Chen G, Gao C, Gao X, Zhang DH, Kuan SF, Burns TF, Hu J. Wnt/β-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer. Mol Cancer Ther. 2018-04-01;17(4):806-813. doi: 10.1158/1535-7163.MCT-17-0561. PubMed PMID: 29167314; PMCID: PMC5882543.

Han J, Goldstein LA, Hou W, Chatterjee S, Burns TF, Rabinowich H. HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC. Autophagy. 2018-03-21;14(6):958-971. doi: 10.1080/15548627.2018.1434471. PubMed PMID: 29561705; PMCID: PMC6103412.

Iyengar M, O'Hayer P, Cole A, Sebastian T, Yang K, Coffman L, Buckanovich RJ. CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer. Oncotarget. 2018-03-20;9(21):15658-15672. doi: 10.18632/oncotarget.24585. PubMed PMID: 29644000; PMCID: PMC5884655.

Dolezal JM, Dash AP, Prochownik EV. Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers. BMC Cancer. 2018-03-12;18(1):275. doi: 10.1186/s12885-018-4178-z. PubMed PMID: 29530001; PMCID: PMC5848553.

Chen J, Nagle AM, Wang YF, Boone DN, Lee AV. Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors. J Biol Chem. 2018-03-09;293(10):3700-3709. doi: 10.1074/jbc.M117.789503. PubMed PMID: 29330302; PMCID: PMC5846141.

Chartoumpekis DV, Yagishita Y, Fazzari M, Palliyaguru DL, Rao UN, Zaravinos A, Khoo NK, Schopfer FJ, Weiss KR, Michalopoulos GK, Sipula I, O'Doherty RM, Kensler TW, Wakabayashi N. Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice. JCI Insight. 2018-03-08;3(5): doi: 10.1172/jci.insight.97735. PubMed PMID: 29515034; PMCID: PMC5922294.

Fourman MS, Mahjoub A, Mandell JB, Yu S, Tebbets JC, Crasto JA, Alexander PE, Weiss KR. Quantitative Primary Tumor Indocyanine Green Measurements Predict Osteosarcoma Metastatic Lung Burden in a Mouse Model. Clin Orthop Relat Res. 2018-03-01;476(3):479-487. doi: 10.1007/s11999.0000000000000003. PubMed PMID: 29408832; PMCID: PMC6260021.

Stabile LP, Farooqui M, Kanterewicz B, Abberbock S, Kurland BF, Diergaarde B, Siegfried JM. Preclinical Evidence for Combined Use of Aromatase Inhibitors and NSAIDs as Preventive Agents of Tobacco-Induced Lung Cancer. J Thorac Oncol. 2018-03-01;13(3):399-412. doi: 10.1016/j.jtho.2017.11.126. PubMed PMID: 29233790; PMCID: PMC5825271.

Alkhalili K, Zenonos G, Tataryn Z, Amankulor N, Engh J. The Utility of Early Postoperative Head Computed Tomography in Brain Tumor Surgery: A Retrospective Analysis of 755 Cases. World Neurosurg. 2018-03-01;111e206-e212. doi: 10.1016/j.wneu.2017.12.038. PubMed PMID: 29258936.

Ekambaram P, Lee JL, Hubel NE, Hu D, Yerneni S, Campbell PG, Pollock N, Klei LR, Concel VJ, Delekta PC, Chinnaiyan AM, Tomlins SA, Rhodes DR, Priedigkeit N, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC. The CARMA3-Bcl10-MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor-Positive Breast Cancer. Cancer Res. 2018-03-01;78(5):1225-1240. doi: 10.1158/0008-5472.CAN-17-1089. PubMed PMID: 29259013; PMCID: PMC6436094.

Zang Y, Pascal LE, Zhou Y, Qiu X, Wei L, Ai J, Nelson JB, Zhong M, Xue B, Wang S, Yang D, Lan L, Shan Y, Wang Z. ELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells. Cancer Lett. 2018-02-28;415198-207. doi: 10.1016/j.canlet.2017.11.028. PubMed PMID: 29179998; PMCID: PMC5761340.

Khazali AS, Clark AM, Wells A. Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy. Br J Cancer. 2018-02-20;118(4):566-576. doi: 10.1038/bjc.2017.414. PubMed PMID: 29169181; PMCID: PMC5830588.

Rothenberger NJ, Somasundaram A, Stabile LP. The Role of the Estrogen Pathway in the Tumor Microenvironment. Int J Mol Sci. 2018-02-19;19(2): doi: 10.3390/ijms19020611. PubMed PMID: 29463044; PMCID: PMC5855833.

Gau D, Lewis T, McDermott L, Wipf P, Koes D, Roy P. Structure-based virtual screening identifies a small-molecule inhibitor of the profilin 1-actin interaction. J Biol Chem. 2018-02-16;293(7):2606-2616. doi: 10.1074/jbc.M117.809137. PubMed PMID: 29282288; PMCID: PMC5818201.

Li F, Pascal LE, Zhou J, Zhou Y, Wang K, Parwani AV, Dhir R, Guo P, He D, Nelson JB, Wang Z. BCL-2 and BCL-XL expression are down-regulated in benign prostate hyperplasia nodules and not affected by finasteride and/or celecoxib. Am J Clin Exp Urol. 2018-02-05;6(1):1-10. PubMed PMID: 29531971; PMCID: PMC5840285.

Volonte D, Vyas AR, Chen C, Dacic S, Stabile LP, Kurland BF, Abberbock SR, Burns TF, Herman JG, Di YP, Galbiati F. Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence. J Biol Chem. 2018-02-02;293(5):1794-1809. doi: 10.1074/jbc.M117.815902. PubMed PMID: 29247004; PMCID: PMC5798308.

Khoo NKH, Li L, Salvatore SR, Schopfer FJ, Freeman BA. Electrophilic fatty acid nitroalkenes regulate Nrf2 and NF-κB signaling:A medicinal chemistry investigation of structure-function relationships. Sci Rep. 2018-02-02;8(1):2295. doi: 10.1038/s41598-018-20460-8. PubMed PMID: 29396403; PMCID: PMC5797128.

Mathers AR, Carey CD, Killeen ME, Salvatore SR, Ferris LK, Freeman BA, Schopfer FJ, Falo LD Jr. Topical electrophilic nitro-fatty acids potentiate cutaneous inflammation. Free Radic Biol Med. 2018-02-01;11531-42. doi: 10.1016/j.freeradbiomed.2017.11.009. PubMed PMID: 29132974; PMCID: PMC5767521.

Beckwitt CH, Clark AM, Wheeler S, Taylor DL, Stolz DB, Griffith L, Wells A. Liver 'organ on a chip'. Exp Cell Res. 2018-02-01;363(1):15-25. doi: 10.1016/j.yexcr.2017.12.023. PubMed PMID: 29291400; PMCID: PMC5944300.

Shao H, Wang A, Lauffenburger D, Wells A. Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain. Int J Biochem Cell Biol. 2018-02-01;9573-84. doi: 10.1016/j.biocel.2017.12.014. PubMed PMID: 29274473; PMCID: PMC5803314.

Woodcock CC, Huang Y, Woodcock SR, Salvatore SR, Singh B, Golin-Bisello F, Davidson NE, Neumann CA, Freeman BA, Wendell SG. Nitro-fatty acid inhibition of triple-negative breast cancer cell viability, migration, invasion, and tumor growth. J Biol Chem. 2018-01-26;293(4):1120-1137. doi: 10.1074/jbc.M117.814368. PubMed PMID: 29158255; PMCID: PMC5787792.

Russell JO, Monga SP. Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology. Annu Rev Pathol. 2018-01-24;13351-378. doi: 10.1146/annurev-pathol-020117-044010. PubMed PMID: 29125798; PMCID: PMC5927358.

Weiss KR, Zimel MN. Considerations for the Long Term Treatment of Pediatric Sarcoma Survivors. Indian J Orthop. 2018-01-01;52(1):77-80. doi: 10.4103/ortho.IJOrtho_248_17. PubMed PMID: 29416174; PMCID: PMC5791236.

Penn CA, Yang K, Zong H, Lim JY, Cole A, Yang D, Baker J, Goonewardena SN, Buckanovich RJ. Therapeutic Impact of Nanoparticle Therapy Targeting Tumor-Associated Macrophages. Mol Cancer Ther. 2018-01-01;17(1):96-106. doi: 10.1158/1535-7163.MCT-17-0688. PubMed PMID: 29133618; PMCID: PMC5752569.

Katz TA, Wu AH, Stanczyk FZ, Wang R, Koh WP, Yuan JM, Oesterreich S, Butler LM. Determinants of prolactin in postmenopausal Chinese women in Singapore. Cancer Causes Control. 2018-01-01;29(1):51-62. doi: 10.1007/s10552-017-0978-8. PubMed PMID: 29124543; PMCID: PMC5962355.

Hopkins BL, Nadler M, Skoko JJ, Bertomeu T, Pelosi A, Shafaei PM, Levine K, Schempf A, Pennarun B, Yang B, Datta D, Bucur O, Ndebele K, Oesterreich S, Yang D, Giulia Rizzo M, Khosravi-Far R, Neumann CA. A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7. Antioxid Redox Signal. 2018-01-01;28(1):62-77. doi: 10.1089/ars.2016.6871. PubMed PMID: 28398822; PMCID: PMC5695745.

Whirledge S, DeFranco DB. Glucocorticoid Signaling in Health and Disease: Insights From Tissue-Specific GR Knockout Mice. Endocrinology. 2018-01-01;159(1):46-64. doi: 10.1210/en.2017-00728. PubMed PMID: 29029225; PMCID: PMC5761604.

Li Z, Levine KM, Bahreini A, Wang P, Chu D, Park BH, Oesterreich S, Lee AV. Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells. Endocrinology. 2018-01-01;159(1):285-296. doi: 10.1210/en.2017-00693. PubMed PMID: 29029116; PMCID: PMC5761602.

Tsuji W, Valentin JE, Marra KG, Donnenberg AD, Donnenberg VS, Rubin JP. An Animal Model of Local Breast Cancer Recurrence in the Setting of Autologous Fat Grafting for Breast Reconstruction. Stem Cells Transl Med. 2018-01-01;7(1):125-134. doi: 10.1002/sctm.17-0062. PubMed PMID: 29283514; PMCID: PMC5746146.

Raghu VK, Beckwitt CH, Warita K, Wells A, Benos PV, Oltvai ZN. Biomarker identification for statin sensitivity of cancer cell lines. Biochem Biophys Res Commun. 2018-01-01;495(1):659-665. doi: 10.1016/j.bbrc.2017.11.065. PubMed PMID: 29146185; PMCID: PMC5827944.

Ancevski Hunter K, Friedland DM, Villaruz LC, Burns TF. First-Line Osimertinib in Patients with Treatment-Naive Somatic or Germline EGFR T790M-Mutant Metastatic NSCLC. J Thorac Oncol. 2018-01-01;13(1):e3-e5. doi: 10.1016/j.jtho.2017.09.1963. PubMed PMID: 28989039.

Pinilla-Macua I, Grassart A, Duvvuri U, Watkins SC, Sorkin A. EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo. Elife. 2017-12-21;6 doi: 10.7554/eLife.31993. PubMed PMID: 29268862; PMCID: PMC5741375.

Müller S, Kohanbash G, Liu SJ, Alvarado B, Carrera D, Bhaduri A, Watchmaker PB, Yagnik G, Di Lullo E, Malatesta M, Amankulor NM, Kriegstein AR, Lim DA, Aghi M, Okada H, Diaz A. Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment. Genome Biol. 2017-12-20;18(1):234. doi: 10.1186/s13059-017-1362-4. PubMed PMID: 29262845; PMCID: PMC5738907.

Pearson AT, Ingram P, Bai S, O'Hayer P, Chung J, Yoon E, Jackson T, Buckanovich RJ. Sampling from single-cell observations to predict tumor cell growth in-vitro and in-vivo. Oncotarget. 2017-12-19;8(67):111176-111189. doi: 10.18632/oncotarget.22693. PubMed PMID: 29340046; PMCID: PMC5762314.

Dombernowsky SL, Schwarz J, Samsøe-Petersen J, Albrechtsen R, Jensen KB, Thomas G, Kveiborg M. Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc(Min) model of colorectal cancer. Oncotarget. 2017-12-12;8(65):108303-108315. doi: 10.18632/oncotarget.22661. PubMed PMID: 29312533; PMCID: PMC5752446.

Korde A, Jin L, Zhang JG, Ramaswamy A, Hu B, Kolahian S, Guardela BJ, Herazo-Maya J, Siegfried JM, Stabile L, Pisani MA, Herbst RS, Kaminski N, Elias JA, Puchalski JT, Takyar SS. Lung Endothelial MicroRNA-1 Regulates Tumor Growth and Angiogenesis. Am J Respir Crit Care Med. 2017-12-01;196(11):1443-1455. doi: 10.1164/rccm.201610-2157OC. PubMed PMID: 28853613; PMCID: PMC5736970.

Wang Y, Pascal LE, Zhong M, Ai J, Wang D, Jing Y, Pilch J, Song Q, Rigatti LH, Graham LE, Nelson JB, Parwani AV, Wang Z. Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice. Endocrinology. 2017-12-01;158(12):4189-4205. doi: 10.1210/en.2017-00409. PubMed PMID: 29029019; PMCID: PMC5711381.

Zhu Y, Gu L, Li Y, Lin X, Shen H, Cui K, Chen L, Zhou F, Zhao Q, Zhang J, Zhong B, Prochownik E, Li Y. miR-148a inhibits colitis and colitis-associated tumorigenesis in mice. Cell Death Differ. 2017-12-01;24(12):2199-2209. doi: 10.1038/cdd.2017.151. PubMed PMID: 28960206; PMCID: PMC5686357.

Liu C, Ren YF, Dong J, Ke MY, Ma F, Monga SPS, Wu R, Lv Y, Zhang XF. Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma. Cancer Lett. 2017-12-01;41020-31. doi: 10.1016/j.canlet.2017.09.013. PubMed PMID: 28942012.

Yochum ZA, Cades J, Mazzacurati L, Neumann NM, Khetarpal SK, Chatterjee S, Wang H, Attar MA, Huang EH, Chatley SN, Nugent K, Somasundaram A, Engh JA, Ewald AJ, Cho YJ, Rudin CM, Tran PT, Burns TF. A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer. Mol Cancer Res. 2017-12-01;15(12):1764-1776. doi: 10.1158/1541-7786.MCR-17-0298. PubMed PMID: 28851812; PMCID: PMC5712248.

Godse NR, Khan N, Yochum ZA, Gomez-Casal R, Kemp C, Shiwarski DJ, Seethala RS, Kulich S, Seshadri M, Burns TF, Duvvuri U. TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression. Clin Cancer Res. 2017-12-01;23(23):7324-7332. doi: 10.1158/1078-0432.CCR-17-1561. PubMed PMID: 28899969; PMCID: PMC5898434.

Martin LA, Ribas R, Simigdala N, Schuster E, Pancholi S, Tenev T, Gellert P, Buluwela L, Harrod A, Thornhill A, Nikitorowicz-Buniak J, Bhamra A, Turgeon MO, Poulogiannis G, Gao Q, Martins V, Hills M, Garcia-Murillas I, Fribbens C, Patani N, Li Z, Sikora MJ, Turner N, Zwart W, Oesterreich S, Carroll J, Ali S, Dowsett M. Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance. Nat Commun. 2017-11-30;8(1):1865. doi: 10.1038/s41467-017-01864-y. PubMed PMID: 29192207; PMCID: PMC5709387.

Samanta S, Tamura S, Dubeau L, Mhawech-Fauceglia P, Miyagi Y, Kato H, Lieberman R, Buckanovich RJ, Lin YG, Neamati N. Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer. Oncotarget. 2017-11-28;8(61):103543-103556. doi: 10.18632/oncotarget.21569. PubMed PMID: 29262583; PMCID: PMC5732749.

Dioufa N, Clark AM, Ma B, Beckwitt CH, Wells A. Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells. Mol Cancer. 2017-11-14;16(1):172. doi: 10.1186/s12943-017-0740-6. PubMed PMID: 29137633; PMCID: PMC5686836.

Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV. Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation. Cancer Res. 2017-11-01;77(21):5795-5807. doi: 10.1158/0008-5472.CAN-17-1325. PubMed PMID: 28883002; PMCID: PMC5668145.

Helfield BL, Chen X, Qin B, Watkins SC, Villanueva FS. Mechanistic Insight into Sonoporation with Ultrasound-Stimulated Polymer Microbubbles. Ultrasound Med Biol. 2017-11-01;43(11):2678-2689. doi: 10.1016/j.ultrasmedbio.2017.07.017. PubMed PMID: 28847500; PMCID: PMC5644032.

Pascal LE, Masoodi KZ, Liu J, Qiu X, Song Q, Wang Y, Zang Y, Yang T, Wang Y, Rigatti LH, Chandran U, Colli LM, Vencio RZN, Lu Y, Zhang J, Wang Z. Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia. J Endocrinol. 2017-11-01;235(2):123-136. doi: 10.1530/JOE-17-0112. PubMed PMID: 28870994; PMCID: PMC5679084.

Spagnolo DM, Al-Kofahi Y, Zhu P, Lezon TR, Gough A, Stern AM, Lee AV, Ginty F, Sarachan B, Taylor DL, Chennubhotla SC. Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images. Cancer Res. 2017-11-01;77(21):e71-e74. doi: 10.1158/0008-5472.CAN-17-0676. PubMed PMID: 29092944; PMCID: PMC5683175.

Puliga E, Min Q, Tao J, Zhang R, Pradhan-Sundd T, Poddar M, Singh S, Columbano A, Yu J, Monga SP. Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer. Am J Pathol. 2017-11-01;187(11):2473-2485. doi: 10.1016/j.ajpath.2017.07.005. PubMed PMID: 28807594; PMCID: PMC5809589.

Gau D, Veon W, Capasso TL, Bottcher R, Shroff S, Roman BL, Roy P. Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis. Angiogenesis. 2017-11-01;20(4):663-672. doi: 10.1007/s10456-017-9560-y. PubMed PMID: 28638990; PMCID: PMC5985144.

Yoneyama T, Gorry M, Miller MA, Gaither-Davis A, Lin Y, Moss ML, Griffith LG, Lauffenburger DA, Stabile LP, Herman JG, Vujanovic NL. Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates. J Cancer. 2017-10-23;8(19):3916-3932. doi: 10.7150/jca.20779. PubMed PMID: 29187866; PMCID: PMC5705993.

Zhao Y, Laws MJ, Guillen VS, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors. Cancer Res. 2017-10-15;77(20):5602-5613. doi: 10.1158/0008-5472.CAN-17-1265. PubMed PMID: 28904064; PMCID: PMC5645250.

Chen L, Vasilatos SN, Qin Y, Katz TA, Cao C, Wu H, Tasdemir N, Levine KM, Oesterreich S, Davidson NE, Huang Y. Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression. Oncotarget. 2017-10-10;8(47):81737-81753. doi: 10.18632/oncotarget.19387. PubMed PMID: 29137219; PMCID: PMC5669845.

Kader M, Alaoui-El-Azher M, Vorhauer J, Kode BB, Wells JZ, Stolz D, Michalopoulos G, Wells A, Scott M, Ismail N. MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock. PLoS Pathog. 2017-10-01;13(10):e1006644. doi: 10.1371/journal.ppat.1006644. PubMed PMID: 29049365; PMCID: PMC5663626.

Chen ZH, Yu YP, Tao J, Liu S, Tseng G, Nalesnik M, Hamilton R, Bhargava R, Nelson JB, Pennathur A, Monga SP, Luketich JD, Michalopoulos GK, Luo JH. MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice. Gastroenterology. 2017-10-01;153(4):1120-1132.e15. doi: 10.1053/j.gastro.2016.12.036. PubMed PMID: 28245430; PMCID: PMC5572118.

Masoodi KZ, Xu Y, Dar JA, Eisermann K, Pascal LE, Parrinello E, Ai J, Johnston PA, Nelson JB, Wipf P, Wang Z. Inhibition of Androgen Receptor Nuclear Localization and Castration-Resistant Prostate Tumor Growth by Pyrroloimidazole-based Small Molecules. Mol Cancer Ther. 2017-10-01;16(10):2120-2129. doi: 10.1158/1535-7163.MCT-17-0176. PubMed PMID: 28655783; PMCID: PMC5628124.

Masoodi KZ, Eisermann K, Yang Z, Dar JA, Pascal LE, Nguyen M, O'Malley K, Parrinello E, Feturi FG, Kenefake AN, Nelson JB, Johnston PA, Wipf P, Wang Z. Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone. Endocrinology. 2017-10-01;158(10):3152-3161. doi: 10.1210/en.2017-00408. PubMed PMID: 28977599; PMCID: PMC5659684.

Kikuchi A, Pradhan-Sundd T, Singh S, Nagarajan S, Loizos N, Monga SP. Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration. Am J Pathol. 2017-10-01;187(10):2273-2287. doi: 10.1016/j.ajpath.2017.06.009. PubMed PMID: 28734947; PMCID: PMC5809633.

Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL, Monga SP. Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. Exp Biol Med (Maywood). 2017-10-01;242(16):1605-1616. doi: 10.1177/1535370217707731. PubMed PMID: 28467181; PMCID: PMC5661767.

Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. 2017-09-21;130(12):1430-1440. doi: 10.1182/blood-2017-02-768234. PubMed PMID: 28694326; PMCID: PMC5609333.

Chatterjee S, Burns TF. Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach. Int J Mol Sci. 2017-09-15;18(9): doi: 10.3390/ijms18091978. PubMed PMID: 28914774; PMCID: PMC5618627.

Gyanchandani R, Kota KJ, Jonnalagadda AR, Minteer T, Knapick BA, Oesterreich S, Brufsky AM, Lee AV, Puhalla SL. Detection of ESR1 mutations in circulating cell-free DNA from patients with metastatic breast cancer treated with palbociclib and letrozole. Oncotarget. 2017-09-15;8(40):66901-66911. doi: 10.18632/oncotarget.11383. PubMed PMID: 28978004; PMCID: PMC5620144.

Priedigkeit N, Watters RJ, Lucas PC, Basudan A, Bhargava R, Horne W, Kolls JK, Fang Z, Rosenzweig MQ, Brufsky AM, Weiss KR, Oesterreich S, Lee AV. Exome-capture RNA sequencing of decade-old breast cancers and matched decalcified bone metastases. JCI Insight. 2017-09-07;2(17): doi: 10.1172/jci.insight.95703. PubMed PMID: 28878133; PMCID: PMC5621874.

Yates CC, Rodrigues M, Nuschke A, Johnson ZI, Whaley D, Stolz D, Newsome J, Wells A. Multipotent stromal cells/mesenchymal stem cells and fibroblasts combine to minimize skin hypertrophic scarring. Stem Cell Res Ther. 2017-09-05;8(1):193. doi: 10.1186/s13287-017-0644-9. PubMed PMID: 28874184; PMCID: PMC5585998.

El-Hefnawy T, Hernandez C, Stabile LP. The endocrine disrupting alkylphenols and 4,4'-DDT interfere with estrogen conversion and clearance by mouse liver cytosol. Reprod Biol. 2017-09-01;17(3):185-192. doi: 10.1016/j.repbio.2017.04.003. PubMed PMID: 28532594.

Shao H, Lauffenburger D, Wells A. Tyro3 carboxyl terminal region confers stability and contains the autophosphorylation sites. Biochem Biophys Res Commun. 2017-08-26;490(3):1074-1079. doi: 10.1016/j.bbrc.2017.06.168. PubMed PMID: 28668391; PMCID: PMC5553559.

Chen Q, Xu B, Lan L, Yang D, Yang M, Jiang J, Lu B, Shen Y. High mRNA expression level of IL-6R was associated with better prognosis for patients with ovarian cancer: a pooled meta-analysis. Sci Rep. 2017-08-18;7(1):8769. doi: 10.1038/s41598-017-09333-8. PubMed PMID: 28821817; PMCID: PMC5562889.

Kulkarni S, Dolezal JM, Wang H, Jackson L, Lu J, Frodey BP, Dosunmu-Ogunbi A, Li Y, Fromherz M, Kang A, Santana-Santos L, Benos PV, Prochownik EV. Ribosomopathy-like properties of murine and human cancers. PLoS One. 2017-08-18;12(8):e0182705. doi: 10.1371/journal.pone.0182705. PubMed PMID: 28820908; PMCID: PMC5562309.

Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP. Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload. J Hepatol. 2017-08-01;67(2):360-369. doi: 10.1016/j.jhep.2017.03.012. PubMed PMID: 28341391; PMCID: PMC5515705.

Chatterjee S, Huang EH, Christie I, Burns TF. Reactivation of the p90RSK-CDC25C Pathway Leads to Bypass of the Ganetespib-Induced G(2)-M Arrest and Mediates Acquired Resistance to Ganetespib in KRAS-Mutant NSCLC. Mol Cancer Ther. 2017-08-01;16(8):1658-1668. doi: 10.1158/1535-7163.MCT-17-0114. PubMed PMID: 28566436; PMCID: PMC5544554.

Tarhini AA, Rafique I, Floros T, Tran P, Gooding WE, Villaruz LC, Burns TF, Friedland DM, Petro DP, Farooqui M, Gomez-Garcia J, Gaither-Davis A, Dacic S, Argiris A, Socinski MA, Stabile LP, Siegfried JM. Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer. Cancer. 2017-08-01;123(15):2936-2944. doi: 10.1002/cncr.30717. PubMed PMID: 28472537; PMCID: PMC5517339.

Yang D, Zhang M, Gold B. Origin of Somatic Mutations in β-Catenin versus Adenomatous Polyposis Coli in Colon Cancer: Random Mutagenesis in Animal Models versus Nonrandom Mutagenesis in Humans. Chem Res Toxicol. 2017-07-17;30(7):1369-1375. doi: 10.1021/acs.chemrestox.7b00092. PubMed PMID: 28578586.

Andersen CL, Sikora MJ, Boisen MM, Ma T, Christie A, Tseng G, Park Y, Luthra S, Chandran U, Haluska P, Mantia-Smaldone GM, Odunsi K, McLean K, Lee AV, Elishaev E, Edwards RP, Oesterreich S. Active Estrogen Receptor-alpha Signaling in Ovarian Cancer Models and Clinical Specimens. Clin Cancer Res. 2017-07-15;23(14):3802-3812. doi: 10.1158/1078-0432.CCR-16-1501. PubMed PMID: 28073843; PMCID: PMC5503796.

Joy M, Gau D, Castellucci N, Prywes R, Roy P. The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms. J Biol Chem. 2017-07-14;292(28):11777-11791. doi: 10.1074/jbc.M117.781104. PubMed PMID: 28546428; PMCID: PMC5512072.

Cheng L, Zhu Y, Han H, Zhang Q, Cui K, Shen H, Zhang J, Yan J, Prochownik E, Li Y. MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice. Cell Death Dis. 2017-07-13;8(7):e2916. doi: 10.1038/cddis.2017.309. PubMed PMID: 28703810; PMCID: PMC5550856.

Kooiman K, van Rooij T, Qin B, Mastik F, Vos HJ, Versluis M, Klibanov AL, de Jong N, Villanueva FS, Chen X. Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification. PLoS One. 2017-07-07;12(7):e0180747. doi: 10.1371/journal.pone.0180747. PubMed PMID: 28686673; PMCID: PMC5501608.

Kota K, Brufsky A, Oesterreich S, Lee A. Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification. Cureus. 2017-07-06;9(7):e1434. doi: 10.7759/cureus.1434. PubMed PMID: 28924522; PMCID: PMC5587405.

Gurda GT, Ambros T, Nikiforova MN, Nikiforov YE, Lucas PC, Dabbs DJ, Lee AV, Brufsky AM, Puhalla SL, Bhargava R. Characterizing Molecular Variants and Clinical Utilization of Next-generation Sequencing in Advanced Breast Cancer. Appl Immunohistochem Mol Morphol. 2017-07-01;25(6):392-398. doi: 10.1097/PAI.0000000000000322. PubMed PMID: 26862949.

Goyal A, Yu FTH, Tenwalde MG, Chen X, Althouse A, Villanueva FS, Pacella JJ. Inertial Cavitation Ultrasound with Microbubbles Improves Reperfusion Efficacy When Combined with Tissue Plasminogen Activator in an In Vitro Model of Microvascular Obstruction. Ultrasound Med Biol. 2017-07-01;43(7):1391-1400. doi: 10.1016/j.ultrasmedbio.2017.02.013. PubMed PMID: 28395964; PMCID: PMC5440195.

Ma T, Liang F, Oesterreich S, Tseng GC. A Joint Bayesian Model for Integrating Microarray and RNA Sequencing Transcriptomic Data. J Comput Biol. 2017-07-01;24(7):647-662. doi: 10.1089/cmb.2017.0056. PubMed PMID: 28541721; PMCID: PMC5510692.

Kim WJ, Newman WC, Amankulor NM. Phase I/II Trial of Combination of Temozolomide Chemotherapy and Immunotherapy With Fusions of Dendritic and Glioma Cells in Patients With Glioblastoma. Neurosurgery. 2017-07-01;81(1):N11. doi: 10.1093/neuros/nyx263. PubMed PMID: 28873996.

Steury MD, Lucas PC, McCabe LR, Parameswaran N. G-protein-coupled receptor kinase-2 is a critical regulator of TNFα signaling in colon epithelial cells. Biochem J. 2017-06-27;474(14):2301-2313. doi: 10.1042/BCJ20170093. PubMed PMID: 28572156; PMCID: PMC5561658.

Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV. Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem. 2017-06-16;292(24):10068-10086. doi: 10.1074/jbc.M117.782052. PubMed PMID: 28432125; PMCID: PMC5473214.

Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, Gibson BW, Goetzman ES. Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain. J Biol Chem. 2017-06-16;292(24):10239-10249. doi: 10.1074/jbc.M117.785022. PubMed PMID: 28458255; PMCID: PMC5473227.

Wang S, Nie D, Rubin JP, Kokai L. Lymphatic Endothelial Cells under Mechanical Stress: Altered Expression of Inflammatory Cytokines and Fibrosis. Lymphat Res Biol. 2017-06-01;15(2):130-135. doi: 10.1089/lrb.2016.0042. PubMed PMID: 28486010.

Thomas G, Aslan JE, Thomas L, Shinde P, Shinde U, Simmen T. Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease. J Cell Sci. 2017-06-01;130(11):1865-1876. doi: 10.1242/jcs.199463. PubMed PMID: 28476937; PMCID: PMC5482974.

Gao X, Chen G, Gao C, Zhang DH, Kuan SF, Stabile LP, Liu G, Hu J. MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance. Mol Oncol. 2017-06-01;11(6):628-639. doi: 10.1002/1878-0261.12055. PubMed PMID: 28306189; PMCID: PMC5467491.

Mathew A, Rajagopal PS, Villgran V, Sandhu GS, Jankowitz RC, Jacob M, Rosenzweig M, Oesterreich S, Brufsky A. Distinct Pattern of Metastases in Patients with Invasive Lobular Carcinoma of the Breast. Geburtshilfe Frauenheilkd. 2017-06-01;77(6):660-666. doi: 10.1055/s-0043-109374. PubMed PMID: 28757653; PMCID: PMC5489406.

Bahreini A, Li Z, Wang P, Levine KM, Tasdemir N, Cao L, Weir HM, Puhalla SL, Davidson NE, Stern AM, Chu D, Park BH, Lee AV, Oesterreich S. Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models. Breast Cancer Res. 2017-05-23;19(1):60. doi: 10.1186/s13058-017-0851-4. PubMed PMID: 28535794; PMCID: PMC5442865.

Chakraborty PK, Mustafi SB, Xiong X, Dwivedi SKD, Nesin V, Saha S, Zhang M, Dhanasekaran D, Jayaraman M, Mannel R, Moore K, McMeekin S, Yang D, Zuna R, Ding K, Tsiokas L, Bhattacharya R, Mukherjee P. MICU1 drives glycolysis and chemoresistance in ovarian cancer. Nat Commun. 2017-05-22;814634. doi: 10.1038/ncomms14634. PubMed PMID: 28530221; PMCID: PMC5477507.

Chatterjee S, Huang EH, Christie I, Kurland BF, Burns TF. Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network. Mol Cancer Ther. 2017-05-01;16(5):793-804. doi: 10.1158/1535-7163.MCT-16-0677. PubMed PMID: 28167505; PMCID: PMC5418121.

Budiu RA, Vlad AM, Nazario L, Bathula C, Cooper KL, Edmed J, Thaker PH, Urban J, Kalinski P, Lee AV, Elishaev EL, Conrads TP, Flint MS. Restraint and Social Isolation Stressors Differentially Regulate Adaptive Immunity and Tumor Angiogenesis in a Breast Cancer Mouse Model. Cancer Clin Oncol. 2017-05-01;6(1):12-24. doi: 10.5539/cco.v6n1p12. PubMed PMID: 28603578; PMCID: PMC5464739.

Newman WC, Kim WJ, Amankulor NM. BRCA1-Regulated RRM2 Expression Protects Glioblastoma Cells from Endogenous Replication Stress and Promotes Tumorigenicity. Neurosurgery. 2017-05-01;80(5):N34. doi: 10.1093/neuros/nyx106. PubMed PMID: 28586489.

Mizoguchi S, Mori K, Wang Z, Liu T, Funahashi Y, Sato F, DeFranco DB, Yoshimura N, Mimata H. Effects of Estrogen Receptor β Stimulation in a Rat Model of Non-Bacterial Prostatic Inflammation. Prostate. 2017-05-01;77(7):803-811. doi: 10.1002/pros.23320. PubMed PMID: 28181685; PMCID: PMC5968815.

Preziosi ME, Monga SP. Update on the Mechanisms of Liver Regeneration. Semin Liver Dis. 2017-05-01;37(2):141-151. doi: 10.1055/s-0037-1601351. PubMed PMID: 28564722; PMCID: PMC5700459.

Tao J, Zhang R, Singh S, Poddar M, Xu E, Oertel M, Chen X, Ganesh S, Abrams M, Monga SP. Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice. Hepatology. 2017-05-01;65(5):1581-1599. doi: 10.1002/hep.28975. PubMed PMID: 27981621; PMCID: PMC5397318.

Priedigkeit N, Hartmaier RJ, Chen Y, Vareslija D, Basudan A, Watters RJ, Thomas R, Leone JP, Lucas PC, Bhargava R, Hamilton RL, Chmielecki J, Puhalla SL, Davidson NE, Oesterreich S, Brufsky AM, Young L, Lee AV. Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases. JAMA Oncol. 2017-05-01;3(5):666-671. doi: 10.1001/jamaoncol.2016.5630. PubMed PMID: 27926948; PMCID: PMC5508875.

Rothenberger NJ, Stabile LP. Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment. Cancers (Basel). 2017-04-24;9(4): doi: 10.3390/cancers9040039. PubMed PMID: 28441771; PMCID: PMC5406714.

Somasundaram A, Burns TF. The next generation of immunotherapy: keeping lung cancer in check. J Hematol Oncol. 2017-04-24;10(1):87. doi: 10.1186/s13045-017-0456-5. PubMed PMID: 28434399; PMCID: PMC5402056.

Zhu L, Ding Y, Chen CY, Wang L, Huo Z, Kim S, Sotiriou C, Oesterreich S, Tseng GC. MetaDCN: meta-analysis framework for differential co-expression network detection with an application in breast cancer. Bioinformatics. 2017-04-15;33(8):1121-1129. doi: 10.1093/bioinformatics/btw788. PubMed PMID: 28031185; PMCID: PMC6041767.

Amankulor NM, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, Margineantu DH, Rao A, Bolouri H, Delrow J, Hockenbery D, Houghton AM, Holland EC. Mutant IDH1 regulates the tumor-associated immune system in gliomas. Genes Dev. 2017-04-15;31(8):774-786. doi: 10.1101/gad.294991.116. PubMed PMID: 28465358; PMCID: PMC5435890.

Siegfried JM, Farooqui M, Rothenberger NJ, Dacic S, Stabile LP. Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer. Oncotarget. 2017-04-11;8(15):24063-24076. doi: 10.18632/oncotarget.16030. PubMed PMID: 28445992; PMCID: PMC5421827.

Lahr RM, Fonseca BD, Ciotti GE, Al-Ashtal HA, Jia JJ, Niklaus MR, Blagden SP, Alain T, Berman AJ. La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs. Elife. 2017-04-07;6 doi: 10.7554/eLife.24146. PubMed PMID: 28379136; PMCID: PMC5419741.

Adamik J, Jin S, Sun Q, Zhang P, Weiss KR, Anderson JL, Silbermann R, Roodman GD, Galson DL. EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation. Mol Cancer Res. 2017-04-01;15(4):405-417. doi: 10.1158/1541-7786.MCR-16-0242-T. PubMed PMID: 28119431; PMCID: PMC5524543.

Kokai LE, Traktuev DO, Zhang L, Merfeld-Clauss S, DiBernardo G, Lu H, Marra KG, Donnenberg A, Donnenberg V, Meyer EM, Fodor PB, March KL, Rubin JP. Adipose Stem Cell Function Maintained with Age: An Intra-Subject Study of Long-Term Cryopreserved Cells. Aesthet Surg J. 2017-04-01;37(4):454-463. doi: 10.1093/asj/sjw197. PubMed PMID: 28364523.

Wells A, Ma B. Friend turned foe: E-cadherin perversely protects micrometastases. Transl Androl Urol. 2017-04-01;6(2):338-340. doi: 10.21037/tau.2017.03.25. PubMed PMID: 28540251; PMCID: PMC5422706.

Wang J, Qin B, Chen X, Wagner WR, Villanueva FS. Ultrasound Molecular Imaging of Angiogenesis Using Vascular Endothelial Growth Factor-Conjugated Microbubbles. Mol Pharm. 2017-03-06;14(3):781-790. doi: 10.1021/acs.molpharmaceut.6b01033. PubMed PMID: 28165246; PMCID: PMC5378155.

Zhou J, Qu Z, Sun F, Han L, Li L, Yan S, Stabile LP, Chen LF, Siegfried JM, Xiao G. Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation. Cancer Immunol Res. 2017-03-01;5(3):257-268. doi: 10.1158/2326-6066.CIR-16-0073. PubMed PMID: 28108629; PMCID: PMC5334370.

Qiu X, Pascal LE, Song Q, Zang Y, Ai J, O'Malley KJ, Nelson JB, Wang Z. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017-03-01;19(3):207-215. doi: 10.1016/j.neo.2017.01.001. PubMed PMID: 28167296; PMCID: PMC5293724.

Jankowitz RC, Oesterreich S, Lee AV, Davidson NE. New Strategies in Metastatic Hormone Receptor-Positive Breast Cancer: Searching for Biomarkers to Tailor Endocrine and Other Targeted Therapies. Clin Cancer Res. 2017-03-01;23(5):1126-1131. doi: 10.1158/1078-0432.CCR-16-0591. PubMed PMID: 27979914; PMCID: PMC5350010.

Zhang M, Lee AV, Rosen JM. The Cellular Origin and Evolution of Breast Cancer. Cold Spring Harb Perspect Med. 2017-03-01;7(3): doi: 10.1101/cshperspect.a027128. PubMed PMID: 28062556; PMCID: PMC5334246.

Panebianco F, Kelly LM, Liu P, Zhong S, Dacic S, Wang X, Singhi AD, Dhir R, Chiosea SI, Kuan SF, Bhargava R, Dabbs D, Trivedi S, Gandhi M, Diaz R, Wald AI, Carty SE, Ferris RL, Lee AV, Nikiforova MN, Nikiforov YE. THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer. Proc Natl Acad Sci U S A. 2017-02-28;114(9):2307-2312. doi: 10.1073/pnas.1614265114. PubMed PMID: 28193878; PMCID: PMC5338560.

Ding Z, Joy M, Kameneva MV, Roy P. Nanomolar concentration of blood-soluble drag-reducing polymer inhibits experimental metastasis of human breast cancer cells. Breast Cancer (Dove Med Press). 2017-02-24;961-65. doi: 10.2147/BCTT.S128777. PubMed PMID: 28280386; PMCID: PMC5340241.

Martínez-Mármol R, Styrczewska K, Pérez-Verdaguer M, Vallejo-Gracia A, Comes N, Sorkin A, Felipe A. Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation. Sci Rep. 2017-02-10;742395. doi: 10.1038/srep42395. PubMed PMID: 28186199; PMCID: PMC5301257.

González Á, García de Durango C, Alonso V, Bravo B, Rodríguez de Gortázar A, Wells A, Forteza J, Vidal-Vanaclocha F. Distinct Osteomimetic Response of Androgen-Dependent and Independent Human Prostate Cancer Cells to Mechanical Action of Fluid Flow: Prometastatic Implications. Prostate. 2017-02-01;77(3):321-333. doi: 10.1002/pros.23270. PubMed PMID: 27813116.

Yu S, Fourman MS, Mahjoub A, Mandell JB, Crasto JA, Greco NG, Weiss KR. Lung cells support osteosarcoma cell migration and survival. BMC Cancer. 2017-01-25;17(1):78. doi: 10.1186/s12885-017-3047-5. PubMed PMID: 28122543; PMCID: PMC5267399.

Somasundaram A, Burns TF. Pembrolizumab in the treatment of metastatic non-small-cell lung cancer: patient selection and perspectives. Lung Cancer (Auckl). 2017-01-11;81-11. doi: 10.2147/LCTT.S105678. PubMed PMID: 28293123; PMCID: PMC5342609.

Jiang C, Ding Z, Joy M, Chakraborty S, Kim SH, Bottcher R, Condeelis J, Singh S, Roy P. A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells. Cell Cycle. 2017-01-01;16(24):2366-2373. doi: 10.1080/15384101.2017.1346759. PubMed PMID: 28699810; PMCID: PMC5788419.

Kim S, Oesterreich S, Kim S, Park Y, Tseng GC. Integrative clustering of multi-level omics data for disease subtype discovery using sequential double regularization. Biostatistics. 2017-01-01;18(1):165-179. doi: 10.1093/biostatistics/kxw039. PubMed PMID: 27549122; PMCID: PMC5255053.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. J Biol Chem. 2016-12-16;291(51):26241-26251. doi: 10.1074/jbc.M116.754218. PubMed PMID: 27738108; PMCID: PMC5159488.

Bahreini A, Levine K, Santana-Santos L, Benos PV, Wang P, Andersen C, Oesterreich S, Lee AV. Non-coding single nucleotide variants affecting estrogen receptor binding and activity. Genome Med. 2016-12-13;8(1):128. doi: 10.1186/s13073-016-0382-0. PubMed PMID: 27964748; PMCID: PMC5154163.

Roos ST, Yu FT, Kamp O, Chen X, Villanueva FS, Pacella JJ. Sonoreperfusion Therapy Kinetics in Whole Blood Using Ultrasound, Microbubbles and Tissue Plasminogen Activator. Ultrasound Med Biol. 2016-12-01;42(12):3001-3009. doi: 10.1016/j.ultrasmedbio.2016.08.013. PubMed PMID: 27687734; PMCID: PMC5328593.

Lu S, Cai C, Yan G, Zhou Z, Wan Y, Chen V, Chen L, Cooper GF, Obeid LM, Hannun YA, Lee AV, Lu X. Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations. Cancer Res. 2016-12-01;76(23):6785-6794. doi: 10.1158/0008-5472.CAN-16-1740. PubMed PMID: 27758891; PMCID: PMC5165695.

Huen AC, Marathi A, Nam PK, Wells A. CXCL11 Expression by Keratinocytes Occurs Transiently Between Reaching Confluence and Cellular Compaction. Adv Wound Care (New Rochelle). 2016-12-01;5(12):517-526. doi: 10.1089/wound.2015.0680. PubMed PMID: 28078185; PMCID: PMC5165675.

Nuschke A, Rodrigues M, Wells AW, Sylakowski K, Wells A. Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation. Stem Cell Res Ther. 2016-12-01;7(1):179. doi: 10.1186/s13287-016-0436-7. PubMed PMID: 27906055; PMCID: PMC5134064.

Spagnolo DM, Gyanchandani R, Al-Kofahi Y, Stern AM, Lezon TR, Gough A, Meyer DE, Ginty F, Sarachan B, Fine J, Lee AV, Taylor DL, Chennubhotla SC. Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers. J Pathol Inform. 2016-11-29;747. doi: 10.4103/2153-3539.194839. PubMed PMID: 27994939; PMCID: PMC5139455.

Onuchic V, Hartmaier RJ, Boone DN, Samuels ML, Patel RY, White WM, Garovic VD, Oesterreich S, Roth ME, Lee AV, Milosavljevic A. Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types. Cell Rep. 2016-11-15;17(8):2075-2086. doi: 10.1016/j.celrep.2016.10.057. PubMed PMID: 27851969; PMCID: PMC5115176.

Yochum ZA, Socinski MA, Burns TF. Paradoxical functions of ZEB1 in EGFR-mutant lung cancer: tumor suppressor and driver of therapeutic resistance. J Thorac Dis. 2016-11-01;8(11):E1528-E1531. doi: 10.21037/jtd.2016.11.59. PubMed PMID: 28066651; PMCID: PMC5179406.

Okabe H, Yang J, Sylakowski K, Yovchev M, Miyagawa Y, Nagarajan S, Chikina M, Thompson M, Oertel M, Baba H, Monga SP, Nejak-Bowen KN. Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice. Hepatology. 2016-11-01;64(5):1652-1666. doi: 10.1002/hep.28774. PubMed PMID: 27533619; PMCID: PMC5074849.

Tao J, Xu E, Zhao Y, Singh S, Li X, Couchy G, Chen X, Zucman-Rossi J, Chikina M, Monga SP. Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin. Hepatology. 2016-11-01;64(5):1587-1605. doi: 10.1002/hep.28601. PubMed PMID: 27097116; PMCID: PMC5073058.

Ma B, Wheeler SE, Clark AM, Whaley DL, Yang M, Wells A. Liver protects metastatic prostate cancer from induced death by activating E-cadherin signaling. Hepatology. 2016-11-01;64(5):1725-1742. doi: 10.1002/hep.28755. PubMed PMID: 27482645; PMCID: PMC5074910.

Nuschke A, Rodrigues M, Rivera J, Yates C, Whaley D, Stolz D, Griffith L, Wells A. Epidermal Growth Factor Tethered to β-Tricalcium Phosphate Bone Scaffolds via a High-Affinity Binding Peptide Enhances Survival of Human Mesenchymal Stem Cells/Multipotent Stromal Cells in an Immune-Competent Parafascial Implantation Assay in Mice. Stem Cells Transl Med. 2016-11-01;5(11):1580-1586. doi: 10.5966/sctm.2015-0326. PubMed PMID: 27400798; PMCID: PMC5070502.

Gyanchandani R, Lin Y, Lin HM, Cooper K, Normolle DP, Brufsky A, Fastuca M, Crosson W, Oesterreich S, Davidson NE, Bhargava R, Dabbs DJ, Lee AV. Intratumor Heterogeneity Affects Gene Expression Profile Test Prognostic Risk Stratification in Early Breast Cancer. Clin Cancer Res. 2016-11-01;22(21):5362-5369. doi: 10.1158/1078-0432.CCR-15-2889. PubMed PMID: 27185370; PMCID: PMC5093028.

Ambrozova G, Fidlerova T, Verescakova H, Koudelka A, Rudolph TK, Woodcock SR, Freeman BA, Kubala L, Pekarova M. Nitro-oleic acid inhibits vascular endothelial inflammatory responses and the endothelial-mesenchymal transition. Biochim Biophys Acta. 2016-11-01;1860(11 Pt A):2428-2437. doi: 10.1016/j.bbagen.2016.07.010. PubMed PMID: 27431604; PMCID: PMC5010974.

Chandran UR, Medvedeva OP, Barmada MM, Blood PD, Chakka A, Luthra S, Ferreira A, Wong KF, Lee AV, Zhang Z, Budden R, Scott JR, Berndt A, Berg JM, Jacobson RS. TCGA Expedition: A Data Acquisition and Management System for TCGA Data. PLoS One. 2016-10-27;11(10):e0165395. doi: 10.1371/journal.pone.0165395. PubMed PMID: 27788220; PMCID: PMC5082933.

Farabaugh SM, Chan BT, Cui X, Dearth RK, Lee AV. Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer. Cell Commun Signal. 2016-10-21;14(1):25. doi: 10.1186/s12964-016-0148-8. PubMed PMID: 27765041; PMCID: PMC5073819.

Dennison JB, Shahmoradgoli M, Liu W, Ju Z, Meric-Bernstam F, Perou CM, Sahin AA, Welm A, Oesterreich S, Sikora MJ, Brown RE, Mills GB. High Intratumoral Stromal Content Defines Reactive Breast Cancer as a Low-risk Breast Cancer Subtype. Clin Cancer Res. 2016-10-15;22(20):5068-5078. doi: 10.1158/1078-0432.CCR-16-0171. PubMed PMID: 27172895; PMCID: PMC5103285.

Volonte D, Liu Z, Shiva S, Galbiati F. Caveolin-1 controls mitochondrial function through regulation of m-AAA mitochondrial protease. Aging (Albany NY). 2016-10-04;8(10):2355-2369. doi: 10.18632/aging.101051. PubMed PMID: 27705926; PMCID: PMC5115893.

Zhang X, Rao A, Sette P, Deibert C, Pomerantz A, Kim WJ, Kohanbash G, Chang Y, Park Y, Engh J, Choi J, Chan T, Okada H, Lotze M, Grandi P, Amankulor N. IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression. Neuro Oncol. 2016-10-01;18(10):1402-12. doi: 10.1093/neuonc/now061. PubMed PMID: 27116977; PMCID: PMC5035522.

Lee AV. The Endocrine Society Centennial: 40 Years of Aromatase Inhibitors as Targeted Therapy for Breast Cancer. Endocrinology. 2016-10-01;157(10):3697-3698. doi: 10.1210/en.2016-1623. PubMed PMID: 27599035.

Sikora MJ, Johnson MD, Lee AV, Oesterreich S. Endocrine Response Phenotypes Are Altered by Charcoal-Stripped Serum Variability. Endocrinology. 2016-10-01;157(10):3760-3766. doi: 10.1210/en.2016-1297. PubMed PMID: 27459541; PMCID: PMC5045515.

Klei LR, Hu D, Panek R, Alfano DN, Bridwell RE, Bailey KM, Oravecz-Wilson KI, Concel VJ, Hess EM, Van Beek M, Delekta PC, Gu S, Watkins SC, Ting AT, Gough PJ, Foley KP, Bertin J, McAllister-Lucas LM, Lucas PC. MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage. Cell Rep. 2016-09-27;17(1):221-232. doi: 10.1016/j.celrep.2016.08.080. PubMed PMID: 27681433; PMCID: PMC5087334.

Sikora MJ, Jacobsen BM, Levine K, Chen J, Davidson NE, Lee AV, Alexander CM, Oesterreich S. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016-09-20;18(1):92. doi: 10.1186/s13058-016-0748-7. PubMed PMID: 27650553; PMCID: PMC5028957.

Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ. ATM protein is deficient in over 40% of lung adenocarcinomas. Oncotarget. 2016-09-06;7(36):57714-57725. doi: 10.18632/oncotarget.9757. PubMed PMID: 27259260; PMCID: PMC5295384.

Helfield B, Chen X, Watkins SC, Villanueva FS. Biophysical insight into mechanisms of sonoporation. Proc Natl Acad Sci U S A. 2016-09-06;113(36):9983-8. doi: 10.1073/pnas.1606915113. PubMed PMID: 27551081; PMCID: PMC5018802.

Black JJ, Yu FT, Schnatz RG, Chen X, Villanueva FS, Pacella JJ. Effect of Thrombus Composition and Viscosity on Sonoreperfusion Efficacy in a Model of Micro-Vascular Obstruction. Ultrasound Med Biol. 2016-09-01;42(9):2220-31. doi: 10.1016/j.ultrasmedbio.2016.04.004. PubMed PMID: 27207018; PMCID: PMC4983511.

Erdem C, Nagle AM, Casa AJ, Litzenburger BC, Wang YF, Taylor DL, Lee AV, Lezon TR. Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways. Mol Cell Proteomics. 2016-09-01;15(9):3045-57. doi: 10.1074/mcp.M115.057729. PubMed PMID: 27364358; PMCID: PMC5013316.

Ganesh S, Koser ML, Cyr WA, Chopda GR, Tao J, Shui X, Ying B, Chen D, Pandya P, Chipumuro E, Siddiquee Z, Craig K, Lai C, Dudek H, Monga SP, Wang W, Brown BD, Abrams MT. Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin. Mol Cancer Ther. 2016-09-01;15(9):2143-54. doi: 10.1158/1535-7163.MCT-16-0309. PubMed PMID: 27390343; PMCID: PMC5010976.

Dar MS, Singh P, Singh G, Jamwal G, Hussain SS, Rana A, Akhter Y, Monga SP, Dar MJ. Terminal regions of β-catenin are critical for regulating its adhesion and transcription functions. Biochim Biophys Acta. 2016-09-01;1863(9):2345-57. doi: 10.1016/j.bbamcr.2016.06.010. PubMed PMID: 27368802.

Clark AM, Ma B, Taylor DL, Griffith L, Wells A. Liver metastases: Microenvironments and ex-vivo models. Exp Biol Med (Maywood). 2016-09-01;241(15):1639-52. doi: 10.1177/1535370216658144. PubMed PMID: 27390264; PMCID: PMC4999624.

Johnson JK, Skoda EM, Zhou J, Parrinello E, Wang D, O'Malley K, Eyer BR, Kazancioglu M, Eisermann K, Johnston PA, Nelson JB, Wang Z, Wipf P. Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer. ACS Med Chem Lett. 2016-08-11;7(8):785-90. doi: 10.1021/acsmedchemlett.6b00186. PubMed PMID: 27563404; PMCID: PMC4983742.

Banerjee Mustafi S, Chakraborty PK, Naz S, Dwivedi SK, Street M, Basak R, Yang D, Ding K, Mukherjee P, Bhattacharya R. MDR1 mediated chemoresistance: BMI1 and TIP60 in action. Biochim Biophys Acta. 2016-08-01;1859(8):983-93. doi: 10.1016/j.bbagrm.2016.06.002. PubMed PMID: 27295567; PMCID: PMC4958591.

Liu TT, Grubisha MJ, Frahm KA, Wendell SG, Liu J, Ricke WA, Auchus RJ, DeFranco DB. Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-Reductase Inhibition in Prostate Epithelial Cells. J Biol Chem. 2016-07-08;291(28):14747-60. doi: 10.1074/jbc.M115.711515. PubMed PMID: 27226548; PMCID: PMC4938192.

Yang M, Ma B, Shao H, Clark AM, Wells A. Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells. BMC Cancer. 2016-07-07;16419. doi: 10.1186/s12885-016-2411-1. PubMed PMID: 27387344; PMCID: PMC4936312.

Singh M, Mukundan S, Jaramillo M, Oesterreich S, Sant S. Three-Dimensional Breast Cancer Models Mimic Hallmarks of Size-Induced Tumor Progression. Cancer Res. 2016-07-01;76(13):3732-43. doi: 10.1158/0008-5472.CAN-15-2304. PubMed PMID: 27216179; PMCID: PMC4947371.

Pascal LE, Wang Z. Two paths for stabilization of ERG in prostate carcinogenesis: TMPRSS2-ERG fusions and speckle-type pox virus and zinc finger protein mutations. Asian J Androl. 2016-07-01;18(4):594-5. doi: 10.4103/1008-682X.168793. PubMed PMID: 26763545; PMCID: PMC4955185.

Kim SH, Kaschula CH, Priedigkeit N, Lee AV, Singh SV. Forkhead Box Q1 Is a Novel Target of Breast Cancer Stem Cell Inhibition by Diallyl Trisulfide. J Biol Chem. 2016-06-24;291(26):13495-508. doi: 10.1074/jbc.M116.715219. PubMed PMID: 27129776; PMCID: PMC4919436.

Mu X, Agarwal R, March D, Rothenberg A, Voigt C, Tebbets J, Huard J, Weiss K. Notch Signaling Mediates Skeletal Muscle Atrophy in Cancer Cachexia Caused by Osteosarcoma. Sarcoma. 2016-06-09;20163758162. doi: 10.1155/2016/3758162. PubMed PMID: 27378829; PMCID: PMC4917717.

Newman WC, Williams L, Duvvuri U, Clump DA 2nd, Amankulor N. Hyalinizing Clear Cell Carcinoma with Biopsy-Proven Spinal Metastasis: Case Report and Review of Literature. World Neurosurg. 2016-06-01;90699.e7-699.e10. doi: 10.1016/j.wneu.2016.02.001. PubMed PMID: 26862022.

Li Y, Zhu Y, Prochownik EV. MicroRNA-based screens for synthetic lethal interactions with c-Myc. RNA Dis. 2016-05-30;3(3): doi: 10.14800/rd.1330. PubMed PMID: 27975083; PMCID: PMC5152767.

Gau D, Veon W, Zeng X, Yates N, Shroff SG, Koes DR, Roy P. Threonine 89 Is an Important Residue of Profilin-1 That Is Phosphorylatable by Protein Kinase A. PLoS One. 2016-05-26;11(5):e0156313. doi: 10.1371/journal.pone.0156313. PubMed PMID: 27228149; PMCID: PMC4882052.

Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes. Oncotarget. 2016-05-24;7(21):30379-95. doi: 10.18632/oncotarget.8856. PubMed PMID: 27105497; PMCID: PMC5058687.

Alvarado TF, Puliga E, Preziosi M, Poddar M, Singh S, Columbano A, Nejak-Bowen K, Monga SP. Thyroid Hormone Receptor β Agonist Induces β-Catenin-Dependent Hepatocyte Proliferation in Mice: Implications in Hepatic Regeneration. Gene Expr. 2016-05-24;17(1):19-34. doi: 10.3727/105221616X691631. PubMed PMID: 27226410; PMCID: PMC5215473.

Yu X, Ai J, Cai L, Jing Y, Wang D, Dong J, Pascal LE, Zhang J, Luo R, Wang Z. Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells. Oncotarget. 2016-05-17;7(20):29245-54. doi: 10.18632/oncotarget.8588. PubMed PMID: 27058417; PMCID: PMC5045393.

Huo Z, Ding Y, Liu S, Oesterreich S, Tseng G. Meta-analytic framework for sparse K-means to identify disease subtypes in multiple transcriptomic studies. J Am Stat Assoc. 2016-05-05;111(513):27-42. doi: 10.1080/01621459.2015.1086354. PubMed PMID: 27330233; PMCID: PMC4908837.

Chatterjee S, Bhattacharya S, Socinski MA, Burns TF. HSP90 inhibitors in lung cancer: promise still unfulfilled. Clin Adv Hematol Oncol. 2016-05-01;14(5):346-56. PubMed PMID: 27379696.

Johnston PA, Nguyen MM, Dar JA, Ai J, Wang Y, Masoodi KZ, Shun T, Shinde S, Camarco DP, Hua Y, Huryn DM, Wilson GM, Lazo JS, Nelson JB, Wipf P, Wang Z. Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells. Assay Drug Dev Technol. 2016-05-01;14(4):226-39. doi: 10.1089/adt.2016.716. PubMed PMID: 27187604; PMCID: PMC4876501.

Ding X, Nguyen MM, James IB, Marra KG, Rubin JP, Leers SA, Kim K. Improved Estimation of Ultrasound Thermal Strain Using Pulse Inversion Harmonic Imaging. Ultrasound Med Biol. 2016-05-01;42(5):1182-92. doi: 10.1016/j.ultrasmedbio.2016.01.007. PubMed PMID: 26948260; PMCID: PMC4811719.

Delgado E, Boisen MM, Laskey R, Chen R, Song C, Sallit J, Yochum ZA, Andersen CL, Sikora MJ, Wagner J, Safe S, Elishaev E, Lee A, Edwards RP, Haluska P, Tseng G, Schurdak M, Oesterreich S. High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome. Gynecol Oncol. 2016-05-01;141(2):348-356. doi: 10.1016/j.ygyno.2016.02.030. PubMed PMID: 26946093; PMCID: PMC5154956.

Zang Y, Dong Y, Yang D, Xue B, Li F, Gu P, Zhao H, Wang S, Zhou S, Ying R, Wang Z, Shan Y. Expression and prognostic significance of ELL-associated factor 2 in human prostate cancer. Int Urol Nephrol. 2016-05-01;48(5):695-700. doi: 10.1007/s11255-015-1210-y. PubMed PMID: 26895851; PMCID: PMC4911596.

Lee T, Lee E, Arrollo D, Lucas PC, Parameswaran N. Non-Hematopoietic β-Arrestin1 Confers Protection Against Experimental Colitis. J Cell Physiol. 2016-05-01;231(5):992-1000. doi: 10.1002/jcp.25216. PubMed PMID: 26479868; PMCID: PMC4728047.

Okabe H, Kinoshita H, Imai K, Nakagawa S, Higashi T, Arima K, Uchiyama H, Ikegami T, Harimoto N, Itoh S, Ishiko T, Yoshizumi T, Beppu T, Monga SP, Baba H, Maehara Y. Diverse Basis of β-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis. PLoS One. 2016-04-21;11(4):e0152695. doi: 10.1371/journal.pone.0152695. PubMed PMID: 27100093; PMCID: PMC4839611.

Zhou C, Ramaswamy SS, Johnson DE, Vitturi DA, Schopfer FJ, Freeman BA, Hudmon A, Levitan ES. Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling. Sci Rep. 2016-04-15;623416. doi: 10.1038/srep23416. PubMed PMID: 27079272; PMCID: PMC4832198.

Zhao W, Chen B, Guo X, Wang R, Chang Z, Dong Y, Song K, Wang W, Qi L, Gu Y, Wang C, Yang D, Guo Z. A rank-based transcriptional signature for predicting relapse risk of stage II colorectal cancer identified with proper data sources. Oncotarget. 2016-04-05;7(14):19060-71. doi: 10.18632/oncotarget.7956. PubMed PMID: 26967049; PMCID: PMC4951352.

Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK. A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. Nat Commun. 2016-04-04;711169. doi: 10.1038/ncomms11169. PubMed PMID: 27041221; PMCID: PMC4822037.

Zhang M, Liu G, Xue F, Edwards R, Sood AK, Zhang W, Yang D. Copy number deletion of RAD50 as predictive marker of BRCAness and PARP inhibitor response in BRCA wild type ovarian cancer. Gynecol Oncol. 2016-04-01;141(1):57-64. doi: 10.1016/j.ygyno.2016.01.004. PubMed PMID: 27016230; PMCID: PMC4967351.

Martínez-Mármol R, Comes N, Styrczewska K, Pérez-Verdaguer M, Vicente R, Pujadas L, Soriano E, Sorkin A, Felipe A. Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis. Cell Mol Life Sci. 2016-04-01;73(7):1515-28. doi: 10.1007/s00018-015-2082-0. PubMed PMID: 26542799; PMCID: PMC4836834.

Han H, Chen Y, Cheng L, Prochownik EV, Li Y. microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13. Oncotarget. 2016-03-29;7(13):16409-19. doi: 10.18632/oncotarget.7653. PubMed PMID: 26918941; PMCID: PMC4941324.

Becker MA, Ibrahim YH, Oh AS, Fagan DH, Byron SA, Sarver AL, Lee AV, Shaw LM, Fan C, Perou CM, Yee D. Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer. PLoS One. 2016-03-18;11(3):e0150564. doi: 10.1371/journal.pone.0150564. PubMed PMID: 26991655; PMCID: PMC4798554.

Liu S, Tsai WH, Ding Y, Chen R, Fang Z, Huo Z, Kim S, Ma T, Chang TY, Priedigkeit NM, Lee AV, Luo J, Wang HW, Chung IF, Tseng GC. Comprehensive evaluation of fusion transcript detection algorithms and a meta-caller to combine top performing methods in paired-end RNA-seq data. Nucleic Acids Res. 2016-03-18;44(5):e47. doi: 10.1093/nar/gkv1234. PubMed PMID: 26582927; PMCID: PMC4797269.

Santa-Maria CA, Blackford A, Nguyen AT, Skaar TC, Philips S, Oesterreich S, Rae JM, Desta Z, Robarge J, Henry NL, Storniolo AM, Hayes DF, Blumenthal RS, Ouyang P, Post WS, Flockhart DA, Stearns V, Consortium on Breast Cancer Pharmacogenomics (COBRA). Association of Variants in Candidate Genes with Lipid Profiles in Women with Early Breast Cancer on Adjuvant Aromatase Inhibitor Therapy. Clin Cancer Res. 2016-03-15;22(6):1395-402. doi: 10.1158/1078-0432.CCR-15-1213. PubMed PMID: 26463708; PMCID: PMC4794377.

Donnenberg VS, Huber A, Basse P, Rubin JP, Donnenberg AD. Neither epithelial nor mesenchymal circulating tumor cells isolated from breast cancer patients are tumorigenic in NOD-scid Il2rg(null) mice. NPJ Breast Cancer. 2016-03-09;216004. doi: 10.1038/npjbcancer.2016.4. PubMed PMID: 28721373; PMCID: PMC5515339.

Wang P, Bahreini A, Gyanchandani R, Lucas PC, Hartmaier RJ, Watters RJ, Jonnalagadda AR, Trejo Bittar HE, Berg A, Hamilton RL, Kurland BF, Weiss KR, Mathew A, Leone JP, Davidson NE, Nikiforova MN, Brufsky AM, Ambros TF, Stern AM, Puhalla SL, Lee AV, Oesterreich S. Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients. Clin Cancer Res. 2016-03-01;22(5):1130-7. doi: 10.1158/1078-0432.CCR-15-1534. PubMed PMID: 26500237; PMCID: PMC4775406.

Nikiforova MN, Wald AI, Melan MA, Roy S, Zhong S, Hamilton RL, Lieberman FS, Drappatz J, Amankulor NM, Pollack IF, Nikiforov YE, Horbinski C. Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors. Neuro Oncol. 2016-03-01;18(3):379-87. doi: 10.1093/neuonc/nov289. PubMed PMID: 26681766; PMCID: PMC4767245.

Huang J, Schriefer AE, Cliften PF, Dietzen D, Kulkarni S, Sing S, Monga SP, Rudnick DA. Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration. Am J Pathol. 2016-03-01;186(3):587-99. doi: 10.1016/j.ajpath.2015.10.027. PubMed PMID: 26772417; PMCID: PMC4816713.

Bodnar RJ, Satish L, Yates CC, Wells A. Pericytes: A newly recognized player in wound healing. Wound Repair Regen. 2016-03-01;24(2):204-14. doi: 10.1111/wrr.12415. PubMed PMID: 26969517; PMCID: PMC5036393.

Li X, Cai H, Zheng W, Tong M, Li H, Ao L, Li J, Hong G, Li M, Guan Q, Yang S, Yang D, Lin X, Guo Z. An individualized prognostic signature for gastric cancer patients treated with 5-Fluorouracil-based chemotherapy and distinct multi-omics characteristics of prognostic groups. Oncotarget. 2016-02-23;7(8):8743-55. doi: 10.18632/oncotarget.7087. PubMed PMID: 26840027; PMCID: PMC4891001.

Pinilla-Macua I, Watkins SC, Sorkin A. Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes. Proc Natl Acad Sci U S A. 2016-02-23;113(8):2122-7. doi: 10.1073/pnas.1520301113. PubMed PMID: 26858456; PMCID: PMC4776482.

Hopkins TG, Mura M, Al-Ashtal HA, Lahr RM, Abd-Latip N, Sweeney K, Lu H, Weir J, El-Bahrawy M, Steel JH, Ghaem-Maghami S, Aboagye EO, Berman AJ, Blagden SP. The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer. Nucleic Acids Res. 2016-02-18;44(3):1227-46. doi: 10.1093/nar/gkv1515. PubMed PMID: 26717985; PMCID: PMC4756840.

Chen X, Wang J, Pacella JJ, Villanueva FS. Dynamic Behavior of Microbubbles during Long Ultrasound Tone-Burst Excitation: Mechanistic Insights into Ultrasound-Microbubble Mediated Therapeutics Using High-Speed Imaging and Cavitation Detection. Ultrasound Med Biol. 2016-02-01;42(2):528-538. doi: 10.1016/j.ultrasmedbio.2015.09.017. PubMed PMID: 26603628; PMCID: PMC4698009.

Toptan T, Yousem SA, Ho J, Matsushima Y, Stabile LP, Fernández-Figueras MT, Bhargava R, Ryo A, Moore PS, Chang Y. Survey for human polyomaviruses in cancer. JCI Insight. 2016-02-01;1(2): doi: 10.1172/jci.insight.85562. PubMed PMID: 27034991; PMCID: PMC4811373.

Ko S, Choi TY, Russell JO, So J, Monga SPS, Shin D. Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration. J Hepatol. 2016-02-01;64(2):316-325. doi: 10.1016/j.jhep.2015.10.017. PubMed PMID: 26505118; PMCID: PMC4718879.

Yu FT, Chen X, Wang J, Qin B, Villanueva FS. Low Intensity Ultrasound Mediated Liposomal Doxorubicin Delivery Using Polymer Microbubbles. Mol Pharm. 2016-01-04;13(1):55-64. doi: 10.1021/acs.molpharmaceut.5b00421. PubMed PMID: 26567985; PMCID: PMC5378154.

Ambrozova G, Martiskova H, Koudelka A, Ravekes T, Rudolph TK, Klinke A, Rudolph V, Freeman BA, Woodcock SR, Kubala L, Pekarova M. Nitro-oleic acid modulates classical and regulatory activation of macrophages and their involvement in pro-fibrotic responses. Free Radic Biol Med. 2016-01-01;90252-260. doi: 10.1016/j.freeradbiomed.2015.11.026. PubMed PMID: 26620549; PMCID: PMC4748956.

Helfield B, Chen X, Qin B, Villanueva FS. Individual lipid encapsulated microbubble radial oscillations: Effects of fluid viscosity. J Acoust Soc Am. 2016-01-01;139(1):204-14. doi: 10.1121/1.4939123. PubMed PMID: 26827018; PMCID: PMC4714991.

Mu X, Patel S, Mektepbayeva D, Mahjoub A, Huard J, Weiss K. Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells. Sarcoma. 2015-12-24;2015784954. doi: 10.1155/2015/784954. PubMed PMID: 26819566; PMCID: PMC4706975.

Boisen MM, Andersen CL, Sreekumar S, Stern AM, Oesterreich S. Treating gynecologic malignancies with selective estrogen receptor downregulators (SERDs): promise and challenges. Mol Cell Endocrinol. 2015-12-15;418 Pt 3322-33. doi: 10.1016/j.mce.2015.04.035. PubMed PMID: 26276546.

Davar D, Socinski MA, Dacic S, Burns TF. Near complete response after single dose of nivolumab in patient with advanced heavily pre-treated KRAS mutant pulmonary adenocarcinoma. Exp Hematol Oncol. 2015-12-14;434. doi: 10.1186/s40164-015-0029-7. PubMed PMID: 26673119; PMCID: PMC4678465.

Bhattacharya S, Socinski MA, Burns TF. KRAS mutant lung cancer: progress thus far on an elusive therapeutic target. Clin Transl Med. 2015-12-01;4(1):35. doi: 10.1186/s40169-015-0075-0. PubMed PMID: 26668062; PMCID: PMC4678136.

Wang G, Wang H, Singh S, Zhou P, Yang S, Wang Y, Zhu Z, Zhang J, Chen A, Billiar T, Monga SP, Wang Q. ADAR1 Prevents Liver Injury from Inflammation and Suppresses Interferon Production in Hepatocytes. Am J Pathol. 2015-12-01;185(12):3224-37. doi: 10.1016/j.ajpath.2015.08.002. PubMed PMID: 26453800; PMCID: PMC4729276.

Wang D, Nguyen MM, Masoodi KZ, Singh P, Jing Y, O'Malley K, Dar JA, Dhir R, Wang Z. Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells. Mol Endocrinol. 2015-12-01;29(12):1731-42. doi: 10.1210/me.2015-1112. PubMed PMID: 26371515; PMCID: PMC4664230.

Eisses JF, Criscimanna A, Dionise ZR, Orabi AI, Javed TA, Sarwar S, Jin S, Zhou L, Singh S, Poddar M, Davis AW, Tosun AB, Ozolek JA, Lowe ME, Monga SP, Rohde GK, Esni F, Husain SZ. Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. Am J Pathol. 2015-12-01;185(12):3304-15. doi: 10.1016/j.ajpath.2015.08.006. PubMed PMID: 26476347; PMCID: PMC4729237.

Zhou L, Pradhan-Sundd T, Poddar M, Singh S, Kikuchi A, Stolz DB, Shou W, Li Z, Nejak-Bowen KN, Monga SP. Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis. Am J Pathol. 2015-12-01;185(12):3274-89. doi: 10.1016/j.ajpath.2015.08.019. PubMed PMID: 26485505; PMCID: PMC4729235.

Nayak SR, Harrington E, Boone D, Hartmaier R, Chen J, Pathiraja TN, Cooper KL, Fine JL, Sanfilippo J, Davidson NE, Lee AV, Dabbs D, Oesterreich S. A Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer. Horm Cancer. 2015-12-01;6(5-6):214-24. doi: 10.1007/s12672-015-0230-5. PubMed PMID: 26113056; PMCID: PMC4807402.

Casa AJ, Hochbaum D, Sreekumar S, Oesterreich S, Lee AV. The estrogen receptor alpha nuclear localization sequence is critical for fulvestrant-induced degradation of the receptor. Mol Cell Endocrinol. 2015-11-05;41576-86. doi: 10.1016/j.mce.2015.08.007. PubMed PMID: 26272024.

Siegfried JM, Lin Y, Diergaarde B, Lin HM, Dacic S, Pennathur A, Weissfeld JL, Romkes M, Nukui T, Stabile LP. Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome. Neoplasia. 2015-11-01;17(11):817-25. doi: 10.1016/j.neo.2015.11.002. PubMed PMID: 26678909; PMCID: PMC4681883.

Fortian A, Dionne LK, Hong SH, Kim W, Gygi SP, Watkins SC, Sorkin A. Endocytosis of Ubiquitylation-Deficient EGFR Mutants via Clathrin-Coated Pits is Mediated by Ubiquitylation. Traffic. 2015-11-01;16(11):1137-54. doi: 10.1111/tra.12314. PubMed PMID: 26251007; PMCID: PMC4607634.

Oesterreich S, Henry NL, Kidwell KM, Van Poznak CH, Skaar TC, Dantzer J, Li L, Hangartner TN, Peacock M, Nguyen AT, Rae JM, Desta Z, Philips S, Storniolo AM, Stearns V, Hayes DF, Flockhart DA. Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover. Breast Cancer Res Treat. 2015-11-01;154(2):263-73. doi: 10.1007/s10549-015-3608-8. PubMed PMID: 26536870; PMCID: PMC4807610.

Burgess M, Gorantla V, Weiss K, Tawbi H. Immunotherapy in Sarcoma: Future Horizons. Curr Oncol Rep. 2015-11-01;17(11):52. doi: 10.1007/s11912-015-0476-7. PubMed PMID: 26423769.

Cooper GF, Bahar I, Becich MJ, Benos PV, Berg J, Espino JU, Glymour C, Jacobson RC, Kienholz M, Lee AV, Lu X, Scheines R, Center for Causal Discovery team. The center for causal discovery of biomedical knowledge from big data. J Am Med Inform Assoc. 2015-11-01;22(6):1132-6. doi: 10.1093/jamia/ocv059. PubMed PMID: 26138794; PMCID: PMC5009908.

Bodnar RJ, Wells A. Differential regulation of pericyte function by the CXC receptor 3. Wound Repair Regen. 2015-11-01;23(6):785-96. doi: 10.1111/wrr.12346. PubMed PMID: 26207932; PMCID: PMC4662923.

Wang H, Teriete P, Hu A, Raveendra-Panickar D, Pendelton K, Lazo JS, Eiseman J, Holien T, Misund K, Oliynyk G, Arsenian-Henriksson M, Cosford ND, Sundan A, Prochownik EV. Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. Oncotarget. 2015-10-20;6(32):32380-95. doi: 10.18632/oncotarget.6116. PubMed PMID: 26474287; PMCID: PMC4741700.

Kopechek JA, Carson AR, McTiernan CF, Chen X, Hasjim B, Lavery L, Sen M, Grandis JR, Villanueva FS. Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth. Theranostics. 2015-10-16;5(12):1378-87. doi: 10.7150/thno.12822. PubMed PMID: 26681983; PMCID: PMC4672019.

Leone JP, Bhargava R, Theisen BK, Hamilton RL, Lee AV, Brufsky AM. Expression of high affinity folate receptor in breast cancer brain metastasis. Oncotarget. 2015-10-06;6(30):30327-33. doi: 10.18632/oncotarget.4639. PubMed PMID: 26160847; PMCID: PMC4745802.

Fazzari M, Khoo N, Woodcock SR, Li L, Freeman BA, Schopfer FJ. Generation and esterification of electrophilic fatty acid nitroalkenes in triacylglycerides. Free Radic Biol Med. 2015-10-01;87113-24. doi: 10.1016/j.freeradbiomed.2015.05.033. PubMed PMID: 26066303; PMCID: PMC4615386.

Katz TA, Liao SG, Palmieri VJ, Dearth RK, Pathiraja TN, Huo Z, Shaw P, Small S, Davidson NE, Peters DG, Tseng GC, Oesterreich S, Lee AV. Targeted DNA Methylation Screen in the Mouse Mammary Genome Reveals a Parity-Induced Hypermethylation of Igf1r That Persists Long after Parturition. Cancer Prev Res (Phila). 2015-10-01;8(10):1000-9. doi: 10.1158/1940-6207.CAPR-15-0178. PubMed PMID: 26290394; PMCID: PMC4677681.

Lahr RM, Mack SM, Héroux A, Blagden SP, Bousquet-Antonelli C, Deragon JM, Berman AJ. The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence. Nucleic Acids Res. 2015-09-18;43(16):8077-88. doi: 10.1093/nar/gkv748. PubMed PMID: 26206669; PMCID: PMC4652764.

Brown DD, Dabbs DJ, Lee AV, McGuire KP, Ahrendt GM, Bhargava R, Davidson NE, Brufsky AM, Johnson RR, Oesterreich S, McAuliffe PF. Developing in vitro models of human ductal carcinoma in situ from primary tissue explants. Breast Cancer Res Treat. 2015-09-01;153(2):311-21. doi: 10.1007/s10549-015-3551-8. PubMed PMID: 26283301.

Weiss KR. To B(MP-2) or Not To B(MP-2): Cytokines and Tumor Surgery—Response. Clin Cancer Res. 2015-09-01;21(17):4023. doi: 10.1158/1078-0432.CCR-15-0875. PubMed PMID: 26330507.

Jiang S, Katz TA, Garee JP, DeMayo FJ, Lee AV, Oesterreich S. Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1. Dis Model Mech. 2015-09-01;8(9):1121-7. doi: 10.1242/dmm.019885. PubMed PMID: 26092125; PMCID: PMC4582101.

Pan TJ, Pantanowitz L, Weiss KR. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb. Case Rep Oncol Med. 2015-08-23;2015172603. doi: 10.1155/2015/172603. PubMed PMID: 26366310; PMCID: PMC4561096.

Liao S, Hartmaier RJ, McGuire KP, Puhalla SL, Luthra S, Chandran UR, Ma T, Bhargava R, Modugno F, Davidson NE, Benz S, Lee AV, Tseng GC, Oesterreich S. The molecular landscape of premenopausal breast cancer. Breast Cancer Res. 2015-08-07;17104. doi: 10.1186/s13058-015-0618-8. PubMed PMID: 26251034; PMCID: PMC4531812.

Yang J, Cusimano A, Monga JK, Preziosi ME, Pullara F, Calero G, Lang R, Yamaguchi TP, Nejak-Bowen KN, Monga SP. WNT5A inhibits hepatocyte proliferation and concludes β-catenin signaling in liver regeneration. Am J Pathol. 2015-08-01;185(8):2194-205. doi: 10.1016/j.ajpath.2015.04.021. PubMed PMID: 26100214; PMCID: PMC4530131.

Edmunds LR, Sharma L, Wang H, Kang A, d'Souza S, Lu J, McLaughlin M, Dolezal JM, Gao X, Weintraub ST, Ding Y, Zeng X, Yates N, Prochownik EV. c-Myc and AMPK Control Cellular Energy Levels by Cooperatively Regulating Mitochondrial Structure and Function. PLoS One. 2015-07-31;10(7):e0134049. doi: 10.1371/journal.pone.0134049. PubMed PMID: 26230505; PMCID: PMC4521957.

Jiang C, Veon W, Li H, Hallows KR, Roy P. Epithelial morphological reversion drives Profilin-1-induced elevation of p27(kip1) in mesenchymal triple-negative human breast cancer cells through AMP-activated protein kinase activation. Cell Cycle. 2015-07-15;14(18):2914-23. doi: 10.1080/15384101.2015.1069929. PubMed PMID: 26176334; PMCID: PMC4825560.

Eisermann K, Dar JA, Dong J, Wang D, Masoodi KZ, Wang Z. Poly (A) Binding Protein Cytoplasmic 1 Is a Novel Co-Regulator of the Androgen Receptor. PLoS One. 2015-07-15;10(7):e0128495. doi: 10.1371/journal.pone.0128495. PubMed PMID: 26176602; PMCID: PMC4503479.

Richard S, Wells A, Connor J, Price F. Use of ChemoFx® for Identification of Effective Treatments in Epithelial Ovarian Cancer. PLoS Curr. 2015-07-13;7 doi: 10.1371/currents.eogt.8b0b6fffc7b999b34bc4c8152edbf237. PubMed PMID: 26213638; PMCID: PMC4506277.

Pinilla-Macua I, Sorkin A. Methods to study endocytic trafficking of the EGF receptor. Methods Cell Biol. 2015-07-07;130347-67. doi: 10.1016/bs.mcb.2015.05.008. PubMed PMID: 26360045; PMCID: PMC4836846.

Vitturi DA, Minarrieta L, Salvatore SR, Postlethwait EM, Fazzari M, Ferrer-Sueta G, Lancaster JR Jr, Freeman BA, Schopfer FJ. Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride. Nat Chem Biol. 2015-07-01;11(7):504-10. doi: 10.1038/nchembio.1814. PubMed PMID: 26006011; PMCID: PMC4472503.

Leone JP, Lee AV, Brufsky AM. Prognostic factors and survival of patients with brain metastasis from breast cancer who underwent craniotomy. Cancer Med. 2015-07-01;4(7):989-94. doi: 10.1002/cam4.439. PubMed PMID: 25756607; PMCID: PMC4529337.

Weiss KR. "To B(MP-2) or Not To B(MP-2)" or "Much Ado About Nothing": Are Orthobiologics in Tumor Surgery Worth the Risks? Clin Cancer Res. 2015-07-01;21(13):2889-91. doi: 10.1158/1078-0432.CCR-14-3069. PubMed PMID: 25609065.

Zanetti A, Grata M, Etling EB, Panday R, Villanueva FS, Toma C. Suspension-Expansion of Bone Marrow Results in Small Mesenchymal Stem Cells Exhibiting Increased Transpulmonary Passage Following Intravenous Administration. Tissue Eng Part C Methods. 2015-07-01;21(7):683-92. doi: 10.1089/ten.TEC.2014.0344. PubMed PMID: 25567723; PMCID: PMC4499773.

Lee AV, Oesterreich S, Davidson NE. MCF-7 cells--changing the course of breast cancer research and care for 45 years. J Natl Cancer Inst. 2015-07-01;107(7): doi: 10.1093/jnci/djv073. PubMed PMID: 25828948.

Donnenberg AD, Meyer EM, Rubin JP, Donnenberg VS. The cell-surface proteome of cultured adipose stromal cells. Cytometry A. 2015-07-01;87(7):665-74. doi: 10.1002/cyto.a.22682. PubMed PMID: 25929697.

Ma B, Khazali A, Wells A. CXCR3 in carcinoma progression. Histol Histopathol. 2015-07-01;30(7):781-92. doi: 10.14670/HH-11-594. PubMed PMID: 25663474; PMCID: PMC4571436.

Wang H, Sharma L, Lu J, Finch P, Fletcher S, Prochownik EV. Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion. Oncotarget. 2015-06-30;6(18):15857-70. doi: 10.18632/oncotarget.4327. PubMed PMID: 26036281; PMCID: PMC4599242.

Leach DA, Need EF, Toivanen R, Trotta AP, Palethorpe HM, Tamblyn DJ, Kopsaftis T, England GM, Smith E, Drew PA, Pinnock CB, Lee P, Holst J, Risbridger GP, Chopra S, DeFranco DB, Taylor RA, Buchanan G. Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome. Oncotarget. 2015-06-30;6(18):16135-50. doi: 10.18632/oncotarget.3873. PubMed PMID: 25965833; PMCID: PMC4599261.

Dombernowsky SL, Samsøe-Petersen J, Petersen CH, Instrell R, Hedegaard AM, Thomas L, Atkins KM, Auclair S, Albrechtsen R, Mygind KJ, Fröhlich C, Howell M, Parker P, Thomas G, Kveiborg M. The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17. Nat Commun. 2015-06-25;67518. doi: 10.1038/ncomms8518. PubMed PMID: 26108729; PMCID: PMC4481878.

Guo W, Keener AL, Jing Y, Cai L, Ai J, Zhang J, Fisher AL, Fu G, Wang Z. FOXA1 modulates EAF2 regulation of AR transcriptional activity, cell proliferation, and migration in prostate cancer cells. Prostate. 2015-06-15;75(9):976-87. doi: 10.1002/pros.22982. PubMed PMID: 25808853; PMCID: PMC4424106.

Tomas A, Vaughan SO, Burgoyne T, Sorkin A, Hartley JA, Hochhauser D, Futter CE. WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway. Nat Commun. 2015-06-12;67324. doi: 10.1038/ncomms8324. PubMed PMID: 26066081; PMCID: PMC4490399.

Logan GJ, Dabbs DJ, Lucas PC, Jankowitz RC, Brown DD, Clark BZ, Oesterreich S, McAuliffe PF. Molecular drivers of lobular carcinoma in situ. Breast Cancer Res. 2015-06-04;1776. doi: 10.1186/s13058-015-0580-5. PubMed PMID: 26041550; PMCID: PMC4453073.

Soodgupta D, Pan D, Cui G, Senpan A, Yang X, Lu L, Weilbaecher KN, Prochownik EV, Lanza GM, Tomasson MH. Small Molecule MYC Inhibitor Conjugated to Integrin-Targeted Nanoparticles Extends Survival in a Mouse Model of Disseminated Multiple Myeloma. Mol Cancer Ther. 2015-06-01;14(6):1286-1294. doi: 10.1158/1535-7163.MCT-14-0774-T. PubMed PMID: 25824336; PMCID: PMC4571491.

Liu TT, Arango-Argoty G, Li Z, Lin Y, Kim SW, Dueck A, Ozsolak F, Monaghan AP, Meister G, DeFranco DB, John B. Noncoding RNAs that associate with YB-1 alter proliferation in prostate cancer cells. RNA. 2015-06-01;21(6):1159-72. doi: 10.1261/rna.045559.114. PubMed PMID: 25904138; PMCID: PMC4436668.

Monga SP. β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis. Gastroenterology. 2015-06-01;148(7):1294-310. doi: 10.1053/j.gastro.2015.02.056. PubMed PMID: 25747274; PMCID: PMC4494085.

Schiff M, Haberberger B, Xia C, Mohsen AW, Goetzman ES, Wang Y, Uppala R, Zhang Y, Karunanidhi A, Prabhu D, Alharbi H, Prochownik EV, Haack T, Häberle J, Munnich A, Rötig A, Taylor RW, Nicholls RD, Kim JJ, Prokisch H, Vockley J. Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency. Hum Mol Genet. 2015-06-01;24(11):3238-47. doi: 10.1093/hmg/ddv074. PubMed PMID: 25721401; PMCID: PMC4424958.

Travers T, Shao H, Joughin BA, Lauffenburger DA, Wells A, Camacho CJ. Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function. Sci Signal. 2015-05-26;8(378):ra51. doi: 10.1126/scisignal.aaa1977. PubMed PMID: 26012634; PMCID: PMC4522051.

Kashyap M, Pore S, Wang Z, Gingrich J, Yoshimura N, Tyagi P. Inflammasomes are important mediators of prostatic inflammation associated with BPH. J Inflamm (Lond). 2015-05-17;1237. doi: 10.1186/s12950-015-0082-3. PubMed PMID: 25991911; PMCID: PMC4436794.

Schweizer R, Tsuji W, Gorantla VS, Marra KG, Rubin JP, Plock JA. The role of adipose-derived stem cells in breast cancer progression and metastasis. Stem Cells Int. 2015-04-27;2015120949. doi: 10.1155/2015/120949. PubMed PMID: 26000019; PMCID: PMC4427098.

Farabaugh SM, Boone DN, Lee AV. Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation. Front Endocrinol (Lausanne). 2015-04-24;659. doi: 10.3389/fendo.2015.00059. PubMed PMID: 25964777; PMCID: PMC4408912.

Jung KY, Wang H, Teriete P, Yap JL, Chen L, Lanning ME, Hu A, Lambert LJ, Holien T, Sundan A, Cosford ND, Prochownik EV, Fletcher S. Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimetics. J Med Chem. 2015-04-09;58(7):3002-24. doi: 10.1021/jm501440q. PubMed PMID: 25734936; PMCID: PMC4955407.

Holt DE, Gill BS, Clump DA, Leeman JE, Burton SA, Amankulor NM, Engh JA, Heron DE. Tumor bed radiosurgery following resection and prior stereotactic radiosurgery for locally persistent brain metastasis. Front Oncol. 2015-04-08;584. doi: 10.3389/fonc.2015.00084. PubMed PMID: 25905042; PMCID: PMC4389371.

Freese KE, Kokai L, Edwards RP, Philips BJ, Sheikh MA, Kelley J, Comerci J, Marra KG, Rubin JP, Linkov F. Adipose-derived stems cells and their role in human cancer development, growth, progression, and metastasis: a systematic review. Cancer Res. 2015-04-01;75(7):1161-8. doi: 10.1158/0008-5472.CAN-14-2744. PubMed PMID: 25736688.

Weiner GM, Chivukula S, Chen CJ, Ding D, Engh JA, Amankulor N. Ommaya reservoir with ventricular catheter placement for chemotherapy with frameless and pinless electromagnetic surgical neuronavigation. Clin Neurol Neurosurg. 2015-03-01;13061-6. doi: 10.1016/j.clineuro.2014.12.018. PubMed PMID: 25590664.

Wendell SG, Golin-Bisello F, Wenzel S, Sobol RW, Holguin F, Freeman BA. 15-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy ω-3 fatty acids. J Biol Chem. 2015-02-27;290(9):5868-80. doi: 10.1074/jbc.M114.635151. PubMed PMID: 25586183; PMCID: PMC4342494.

Mu X, Brynien D, Weiss KR. The HDAC inhibitor Vorinostat diminishes the in vitro metastatic behavior of Osteosarcoma cells. Biomed Res Int. 2015-02-17;2015290368. doi: 10.1155/2015/290368. PubMed PMID: 25785263; PMCID: PMC4346695.

Furukawa M, Wheeler S, Clark AM, Wells A. Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells. PLoS One. 2015-01-30;10(1):e0118060. doi: 10.1371/journal.pone.0118060. PubMed PMID: 25635394; PMCID: PMC4311980.

Chen K, Yang D, Li X, Sun B, Song F, Cao W, Brat DJ, Gao Z, Li H, Liang H, Zhao Y, Zheng H, Li M, Buckner J, Patterson SD, Ye X, Reinhard C, Bhathena A, Joshi D, Mischel PS, Croce CM, Wang YM, Raghavakaimal S, Li H, Lu X, Pan Y, Chang H, Ba S, Luo L, Cavenee WK, Zhang W, Hao X. Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy. Proc Natl Acad Sci U S A. 2015-01-27;112(4):1107-12. doi: 10.1073/pnas.1422640112. PubMed PMID: 25583476; PMCID: PMC4313862.

Nie Z, Du MQ, McAllister-Lucas LM, Lucas PC, Bailey NG, Hogaboam CM, Lim MS, Elenitoba-Johnson KS. Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma. Nat Commun. 2015-01-08;65908. doi: 10.1038/ncomms6908. PubMed PMID: 25569716.

Gajula RP, Chettiar ST, Williams RD, Nugent K, Kato Y, Wang H, Malek R, Taparra K, Cades J, Annadanam A, Yoon AR, Fertig E, Firulli BA, Mazzacurati L, Burns TF, Firulli AB, An SS, Tran PT. Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells. Neoplasia. 2015-01-01;17(1):16-31. doi: 10.1016/j.neo.2014.10.009. PubMed PMID: 25622896; PMCID: PMC4309734.

Barroso-González J, Thomas G. Endosome traffic machinery meets the p53-p21 axis. Mol Cell Oncol. 2015-01-01;2(2):e975075. doi: 10.4161/23723556.2014.975075. PubMed PMID: 25815376; PMCID: PMC4372196.

Gau DM, Lesnock JL, Hood BL, Bhargava R, Sun M, Darcy K, Luthra S, Chandran U, Conrads TP, Edwards RP, Kelley JL, Krivak TC, Roy P. BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study. Cell Cycle. 2015-01-01;14(12):1884-92. doi: 10.1080/15384101.2015.1036203. PubMed PMID: 25927284; PMCID: PMC4614952.

Wang H, Ramakrishnan A, Fletcher S, Prochownik EV. A quantitative, surface plasmon resonance-based approach to evaluating DNA binding by the c-Myc oncoprotein and its disruption by small molecule inhibitors. J Biol Methods. 2015-01-01;2(2): doi: 10.14440/jbm.2015.54. PubMed PMID: 26280010; PMCID: PMC4537179.

Kostka D, Friedrich T, Holloway AK, Pollard KS. motifDiverge: a model for assessing the statistical significance of gene regulatory motif divergence between two DNA sequences. Stat Interface. 2015-01-01;8(4):463-476. doi: 10.4310/SII.2015.v8.n4.a6. PubMed PMID: 26709360; PMCID: PMC4689439.

Kikuchi A, Monga SP. PDGFRα in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer. Gene Expr. 2015-01-01;16(3):109-27. doi: 10.3727/105221615X14181438356210. PubMed PMID: 25700367; PMCID: PMC4410163.

Warita K, Warita T, Beckwitt CH, Schurdak ME, Vazquez A, Wells A, Oltvai ZN. Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. Sci Rep. 2014-12-23;47593. doi: 10.1038/srep07593. PubMed PMID: 25534349; PMCID: PMC4274516.

Somasundaram A, Socinski MA, Burns TF. Personalized treatment of EGFR mutant and ALK-positive patients in NSCLC. Expert Opin Pharmacother. 2014-12-01;15(18):2693-708. doi: 10.1517/14656566.2014.971013. PubMed PMID: 25381900.

Shao H, Li S, Watkins SC, Wells A. α-Actinin-4 is required for amoeboid-type invasiveness of melanoma cells. J Biol Chem. 2014-11-21;289(47):32717-28. doi: 10.1074/jbc.M114.579185. PubMed PMID: 25296750; PMCID: PMC4239623.

Park KS, Bayles I, Szlachta-McGinn A, Paul J, Boiko J, Santos P, Liu J, Wang Z, Borghesi L, Milcarek C. Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response. J Immunol. 2014-11-01;193(9):4663-74. doi: 10.4049/jimmunol.1401608. PubMed PMID: 25238757; PMCID: PMC4201982.

Pascal LE, Wang Z. Unzipping androgen action through ZIP9: a novel membrane androgen receptor. Endocrinology. 2014-11-01;155(11):4120-3. doi: 10.1210/en.2014-1749. PubMed PMID: 25325426.

Wang T, Goodman MA, McGough RL, Weiss KR, Rao UN. Immunohistochemical analysis of expressions of RB1, CDK4, HSP90, cPLA2G4A, and CHMP2B is helpful in distinction between myxofibrosarcoma and myxoid liposarcoma. Int J Surg Pathol. 2014-10-01;22(7):589-99. doi: 10.1177/1066896914532539. PubMed PMID: 24788530.

Atkins KM, Thomas LL, Barroso-González J, Thomas L, Auclair S, Yin J, Kang H, Chung JH, Dikeakos JD, Thomas G. The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest. Cell Rep. 2014-09-11;8(5):1545-57. doi: 10.1016/j.celrep.2014.07.049. PubMed PMID: 25159152; PMCID: PMC4285392.

Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate. J Biol Chem. 2014-09-05;289(36):25382-92. doi: 10.1074/jbc.M114.580662. PubMed PMID: 25053415; PMCID: PMC4155699.

Stabile LP, Rothstein ME, Gubish CT, Cunningham DE, Lee N, Siegfried JM. Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened airway HGF. J Thorac Oncol. 2014-09-01;9(9):1285-93. doi: 10.1097/JTO.0000000000000245. PubMed PMID: 25057941; PMCID: PMC4134355.

Dar JA, Masoodi KZ, Eisermann K, Isharwal S, Ai J, Pascal LE, Nelson JB, Wang Z. The N-terminal domain of the androgen receptor drives its nuclear localization in castration-resistant prostate cancer cells. J Steroid Biochem Mol Biol. 2014-09-01;143473-80. doi: 10.1016/j.jsbmb.2014.03.004. PubMed PMID: 24662325; PMCID: PMC4127361.

Amankulor NM, Xu R, Iorgulescu JB, Chapman T, Reiner AS, Riedel E, Lis E, Yamada Y, Bilsky M, Laufer I. The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors. Spine J. 2014-09-01;14(9):1850-9. doi: 10.1016/j.spinee.2013.10.028. PubMed PMID: 24216397.

Wu C, Wang Z, Song X, Feng XS, Abnet CC, He J, Hu N, Zuo XB, Tan W, Zhan Q, Hu Z, He Z, Jia W, Zhou Y, Yu K, Shu XO, Yuan JM, Zheng W, Zhao XK, Gao SG, Yuan ZQ, Zhou FY, Fan ZM, Cui JL, Lin HL, Han XN, Li B, Chen X, Dawsey SM, Liao L, Lee MP, Ding T, Qiao YL, Liu Z, Liu Y, Yu D, Chang J, Wei L, Gao YT, Koh WP, Xiang YB, Tang ZZ, Fan JH, Han JJ, Zhou SL, Zhang P, Zhang DY, Yuan Y, Huang Y, Liu C, Zhai K, Qiao Y, Jin G, Guo C, Fu J, Miao X, Lu C, Yang H, Wang C, Wheeler WA, Gail M, Yeager M, Yuenger J, Guo ET, Li AL, Zhang W, Li XM, Sun LD, Ma BG, Li Y, Tang S, Peng XQ, Liu J, Hutchinson A, Jacobs K, Giffen C, Burdette L, Fraumeni JF Jr, Shen H, Ke Y, Zeng Y, Wu T, Kraft P, Chung CC, Tucker MA, Hou ZC, Liu YL, Hu YL, Liu Y, Wang L, Yuan G, Chen LS, Liu X, Ma T, Meng H, Sun L, Li XM, Li XM, Ku JW, Zhou YF, Yang LQ, Wang Z, Li Y, Qige Q, Yang WJ, Lei GY, Chen LQ, Li EM, Yuan L, Yue WB, Wang R, Wang LW, Fan XP, Zhu FH, Zhao WX, Mao YM, Zhang M, Xing GL, Li JL, Han M, Ren JL, Liu B, Ren SW, Kong QP, Li F, Sheyhidin I, Wei W, Zhang YR, Feng CW, Wang J, Yang YH, Hao HZ, Bao QD, Liu BC, Wu AQ, Xie D, Yang WC, Wang L, Zhao XH, Chen SQ, Hong JY, Zhang XJ, Freedman ND, Goldstein AM, Lin D, Taylor PR, Wang LD, Chanock SJ. Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. Nat Genet. 2014-09-01;46(9):1001-1006. doi: 10.1038/ng.3064. PubMed PMID: 25129146; PMCID: PMC4212832.

Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A. A microphysiological system model of therapy for liver micrometastases. Exp Biol Med (Maywood). 2014-09-01;239(9):1170-9. doi: 10.1177/1535370214532596. PubMed PMID: 24821820; PMCID: PMC4574864.

Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SPS. Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice. Gastroenterology. 2014-09-01;147(3):690-701. doi: 10.1053/j.gastro.2014.05.004. PubMed PMID: 24837480; PMCID: PMC4143445.

Yang J, Mowry LE, Nejak-Bowen KN, Okabe H, Diegel CR, Lang RA, Williams BO, Monga SP. β-catenin signaling in murine liver zonation and regeneration: a Wnt-Wnt situation! Hepatology. 2014-09-01;60(3):964-76. doi: 10.1002/hep.27082. PubMed PMID: 24700412; PMCID: PMC4139486.

Solomon JD, Heitzer MD, Liu TT, Beumer JH, Parise RA, Normolle DP, Leach DA, Buchanan G, DeFranco DB. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol Cancer Res. 2014-08-01;12(8):1166-80. doi: 10.1158/1541-7786.MCR-13-0395. PubMed PMID: 24825850; PMCID: PMC4134986.

Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery. PLoS One. 2014-07-18;9(7):e102678. doi: 10.1371/journal.pone.0102678. PubMed PMID: 25036749; PMCID: PMC4103836.

Parikh RA, Pascal LE, Davies BJ, Wang Z. Improving intermittent androgen deprivation therapy: lessons learned from basic and translational research. Asian J Androl. 2014-07-01;16(4):505-10. doi: 10.4103/1008-682X.125410. PubMed PMID: 24759577; PMCID: PMC4104071.

Katz TA, Vasilatos SN, Harrington E, Oesterreich S, Davidson NE, Huang Y. Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells. Breast Cancer Res Treat. 2014-07-01;146(1):99-108. doi: 10.1007/s10549-014-3012-9. PubMed PMID: 24924415.

Delgado ER, Yang J, So J, Leimgruber S, Kahn M, Ishitani T, Shin D, Mustata Wilson G, Monga SP. Identification and characterization of a novel small-molecule inhibitor of β-catenin signaling. Am J Pathol. 2014-07-01;184(7):2111-22. doi: 10.1016/j.ajpath.2014.04.002. PubMed PMID: 24819961; PMCID: PMC4076560.

Okabe H, Delgado E, Lee JM, Yang J, Kinoshita H, Hayashi H, Tsung A, Behari J, Beppu T, Baba H, Monga SP. Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma. PLoS One. 2014-06-03;9(6):e98817. doi: 10.1371/journal.pone.0098817. PubMed PMID: 24892551; PMCID: PMC4043833.

Ng YK, Lee JY, Supko KM, Khan A, Torres SM, Berwick M, Ho J, Kirkwood JM, Siegfried JM, Stabile LP. Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment. Melanoma Res. 2014-06-01;24(3):207-18. doi: 10.1097/CMR.0000000000000060. PubMed PMID: 24709886; PMCID: PMC4394744.

Erwin GD, Oksenberg N, Truty RM, Kostka D, Murphy KK, Ahituv N, Pollard KS, Capra JA. Integrating diverse datasets improves developmental enhancer prediction. PLoS Comput Biol. 2014-06-01;10(6):e1003677. doi: 10.1371/journal.pcbi.1003677. PubMed PMID: 24967590; PMCID: PMC4072507.

Fanti M, Singh S, Ledda-Columbano GM, Columbano A, Monga SP. Tri-iodothyronine induces hepatocyte proliferation by protein kinase A-dependent β-catenin activation in rodents. Hepatology. 2014-06-01;59(6):2309-20. doi: 10.1002/hep.26775. PubMed PMID: 24122933; PMCID: PMC3979513.