Inhibitory Mechanisms in the TME
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. Tumour interstitial fluid-enriched phosphoethanolamine suppresses T cell function. Nat Cell Biol. 2025-04-21; doi: 10.1038/s41556-025-01650-9. PubMed PMID: 40258951.
. Distinct CD8(+) T cell dynamics associate with response to neoadjuvant cancer immunotherapies. Cancer Cell. 2025-04-14; doi: 10.1016/j.ccell.2025.02.026. PubMed PMID: 40086437.
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. Intratumoral or Subcutaneous MK-2118, a Non-Cyclic Dinucleotide STING Agonist, With or Without Pembrolizumab for Advanced or Metastatic Solid Tumors or Lymphomas. Clin Cancer Res. 2025-04-01; doi: 10.1158/1078-0432.CCR-24-2824. PubMed PMID: 39846804; PMCID: PMC11964177.
. Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy. Cell Metab. 2025-04-01; doi: 10.1016/j.cmet.2024.12.007. PubMed PMID: 39879981.
. The T cell receptor landscape of childhood brain tumors. Sci Transl Med. 2025-03-19;17(790):eadp0675. doi: 10.1126/scitranslmed.adp0675. PubMed PMID: 40106578.
. NK cells link immune-checkpoint blockade immunotherapy and response in melanoma brain metastases. J Immunother Cancer. 2025-03-18;13(3): doi: 10.1136/jitc-2025-011581. PubMed PMID: 40107674; PMCID: PMC11927483.
. Phase I dose-escalation and pharmacodynamic study of STING agonist E7766 in advanced solid tumors. J Immunother Cancer. 2025-02-20;13(2): doi: 10.1136/jitc-2024-010511. PubMed PMID: 39979069; PMCID: PMC11842995.
. Dysfunctional CD11c(-)CD21(-) extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer. Sci Transl Med. 2025-02-19;17(786):eadh1315. doi: 10.1126/scitranslmed.adh1315. PubMed PMID: 39970232.
. Immuno-epidemiologic mapping of HLA diversity across glioma patient cohorts. Neuro Oncol. 2025-02-14; doi: 10.1093/neuonc/noaf040. PubMed PMID: 39949048.
. Biology of extracellular vesicles and the potential of tumor-derived vesicles for subverting immunotherapy of cancer. J Immunother Cancer. 2025-01-23;13(1): doi: 10.1136/jitc-2024-010376. PubMed PMID: 39855711; PMCID: PMC11759217.
. Advances in LAG3 cancer immunotherapeutics. Trends Cancer. 2025-01-01; doi: 10.1016/j.trecan.2024.10.009. PubMed PMID: 39603977; PMCID: PMC12047404.
. Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children's Oncology Group Bone Tumor Committee Consensus Statement. J Natl Compr Canc Netw. 2024-12-27;1-7. doi: 10.6004/jnccn.2024.7063. PubMed PMID: 39729709; PMCID: PMC11881167.
. Phase 1/2 Study of the Indoleamine 2,3-Dioxygenase 1 Inhibitor Linrodostat Mesylate Combined With Nivolumab or Nivolumab and Ipilimumab in Advanced Solid Tumors or Hematologic Malignancies. Clin Cancer Res. 2024-12-13; doi: 10.1158/1078-0432.CCR-24-0439. PubMed PMID: 39670852.
. CD28 co-stimulation: novel insights and applications in cancer immunotherapy. Nat Rev Immunol. 2024-12-01; doi: 10.1038/s41577-024-01061-1. PubMed PMID: 39054343; PMCID: PMC11598642.
. Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism. Nat Immunol. 2024-12-01; doi: 10.1038/s41590-024-01999-3. PubMed PMID: 39516648; PMCID: PMC11588660.
. Ferroptosis of select skin epithelial cells initiates and maintains chronic systemic immune-mediated psoriatic disease. J Clin Invest. 2024-11-21; doi: 10.1172/JCI183219. PubMed PMID: 39570671; PMCID: PMC11735110.
. Differences in the pathological, transcriptomic, and prognostic implications of lymphoid structures between primary and metastatic cutaneous melanomas. J Immunother Cancer. 2024-11-12;12(11): doi: 10.1136/jitc-2024-009231. PubMed PMID: 39537211; PMCID: PMC11575263.
. Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial. Cancer Cell. 2024-11-11; doi: 10.1016/j.ccell.2024.10.007. PubMed PMID: 39486411; PMCID: PMC11560503.
. The activity of tertiary lymphoid structures in high grade serous ovarian cancer is governed by site, stroma, and cellular interactions. Cancer Cell. 2024-11-11; doi: 10.1016/j.ccell.2024.09.007. PubMed PMID: 39393357.
. A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets. Neuron. 2024-09-25; doi: 10.1016/j.neuron.2024.06.021. PubMed PMID: 39019041; PMCID: PMC11578855.
. NETosis Impact on Tumor Biology, Radiation, and Systemic Therapy Resistance. Clin Cancer Res. 2024-09-13; doi: 10.1158/1078-0432.CCR-24-1363. PubMed PMID: 39007757; PMCID: PMC11398986.
. Jeffrey S Weber, MD, PhD (1952-2024): in memoriam to discovery, friendship and family. J Immunother Cancer. 2024-09-10;12(9): doi: 10.1136/jitc-2024-010464. PubMed PMID: 39260827.
. Assessing clonal changes in T cells over time following immunotherapy is a breeze with Cyclone. Cancer Cell. 2024-09-09;42(9):1491-1493. doi: 10.1016/j.ccell.2024.08.014. PubMed PMID: 39255774.
. Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells. J Immunother Cancer. 2024-08-17;12(8): doi: 10.1136/jitc-2024-009062. PubMed PMID: 39153823; PMCID: PMC11331848.
. Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8(+) T cells to promote antitumor immunity. Cell. 2024-08-08;187(16):4373-4388.e15. doi: 10.1016/j.cell.2024.06.036. PubMed PMID: 39121849; PMCID: PMC11346583.
. LAG-3 and PD-1 synergize on CD8(+) T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity. Cell. 2024-08-08;187(16):4355-4372.e22. doi: 10.1016/j.cell.2024.07.016. PubMed PMID: 39121848; PMCID: PMC11323044.
. Lung Cancer Adoptive Cell Therapy: Inspiring TIL ACT Comes Center Stage. Cancer Discov. 2024-08-02;14(8):1366-1368. doi: 10.1158/2159-8290.CD-24-0645. PubMed PMID: 39091204.
. Dietary commensal wrestles iron from tumor microenvironment to activate antitumoral macrophages. Cancer Res. 2024-08-01; doi: 10.1158/0008-5472.CAN-24-1833. PubMed PMID: 38832925; PMCID: PMC11552448.
. IL-12 induces a B cell-intrinsic IL-12/IFNγ feed-forward loop promoting extrafollicular B cell responses. Nat Immunol. 2024-07-01;25(7):1283-1295. doi: 10.1038/s41590-024-01858-1. PubMed PMID: 38862796; PMCID: PMC11992614.
. Perspectives from the leadership of Journal for ImmunoTherapy of Cancer. J Immunother Cancer. 2024-06-19;12(6): doi: 10.1136/jitc-2024-009661. PubMed PMID: 38901880; PMCID: PMC11191768.
. An IRF2-Expressing Oncolytic Virus Changes the Susceptibility of Tumor Cells to Antitumor T cells and Promotes Tumor Clearance. Cancer Immunol Res. 2024-06-04; doi: 10.1158/2326-6066.CIR-23-0573. PubMed PMID: 38517470; PMCID: PMC11150089.
. Immunotherapy combination approaches: mechanisms, biomarkers and clinical observations. Nat Rev Immunol. 2024-06-01; doi: 10.1038/s41577-023-00973-8. PubMed PMID: 38057451; PMCID: PMC11460566.
. T Cell Exhaustion. Annu Rev Immunol. 2024-06-01; doi: 10.1146/annurev-immunol-090222-110914. PubMed PMID: 38166256.
. Pembrolizumab Versus Placebo as Adjuvant Therapy in Resected Stage IIB or IIC Melanoma: Final Analysis of Distant Metastasis-Free Survival in the Phase III KEYNOTE-716 Study. J Clin Oncol. 2024-05-10;JCO2302355. doi: 10.1200/JCO.23.02355. PubMed PMID: 38452313; PMCID: PMC11095869.
. Neoadjuvant Dual Checkpoint Inhibitors vs Anti-PD1 Therapy in High-Risk Resectable Melanoma: A Pooled Analysis. JAMA Oncol. 2024-05-01; doi: 10.1001/jamaoncol.2023.7333. PubMed PMID: 38546551; PMCID: PMC10979364.
. Unraveling the therapeutic benefit of sequenced chemo-immunotherapy. Clin Cancer Res. 2024-05-01; doi: 10.1158/1078-0432.CCR-23-3736. PubMed PMID: 38372597; PMCID: PMC11062819.
. Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. J Immunother Cancer. 2024-04-18;12(4): doi: 10.1136/jitc-2023-008378. PubMed PMID: 38641350; PMCID: PMC11029323.
. Uveal melanoma immunogenomics predict immunotherapy resistance and susceptibility. Nat Commun. 2024-04-16;15(1):2863. doi: 10.1038/s41467-024-46906-4. PubMed PMID: 38627362; PMCID: PMC11021475.
. SITC Clinical Immuno-Oncology Network (SCION) commentary on measurement and interpretation of essential biomarkers in early clinical trials. J Immunother Cancer. 2024-03-21;12(3): doi: 10.1136/jitc-2023-008655. PubMed PMID: 38519056; PMCID: PMC10961490.
. Therapeutic Hope on the Surface of Ewing Sarcoma. Clin Cancer Res. 2024-03-01; doi: 10.1158/1078-0432.CCR-23-3138. PubMed PMID: 38113033; PMCID: PMC10922950.
. Integrating innate and adaptive immunity in oncolytic virus therapy. Trends Cancer. 2024-02-01; doi: 10.1016/j.trecan.2023.09.012. PubMed PMID: 37880008; PMCID: PMC10922271.
. Metabolic waypoints during T cell differentiation. Nat Immunol. 2024-02-01; doi: 10.1038/s41590-023-01733-5. PubMed PMID: 38238609.
. An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma. Cell Rep. 2024-01-23;43(1):113557. doi: 10.1016/j.celrep.2023.113557. PubMed PMID: 38113141.
. Uncovering the potential of CD40 agonism to enhance immune-checkpoint blockade. Clin Cancer Res. 2024-01-05; doi: 10.1158/1078-0432.CCR-23-2437. PubMed PMID: 37870487; PMCID: PMC10842335.
. Redox and detox: Malate shuttle metabolism keeps exhausted T cells fit. Cell Metab. 2023-12-05;35(12):2101-2103. doi: 10.1016/j.cmet.2023.11.005. PubMed PMID: 38056428.
. B cell-intrinsic Myd88 regulates disease progression in murine lupus. J Exp Med. 2023-12-04;220(12): doi: 10.1084/jem.20230263. PubMed PMID: 37787782; PMCID: PMC10541815.
. The multifunctional protein HMGB1: 50 years of discovery. Nat Rev Immunol. 2023-12-01; doi: 10.1038/s41577-023-00894-6. PubMed PMID: 37322174.
. Adjuvant nivolumab in resected stage IIB/C melanoma: primary results from the randomized, phase 3 CheckMate 76K trial. Nat Med. 2023-11-01; doi: 10.1038/s41591-023-02583-2. PubMed PMID: 37845511; PMCID: PMC10667090.
. The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial. Nat Med. 2023-11-01; doi: 10.1038/s41591-023-02593-0. PubMed PMID: 37857711; PMCID: PMC10667103.
. An oncolytic virus-delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment. J Exp Med. 2023-10-02;220(10): doi: 10.1084/jem.20230053. PubMed PMID: 37552475; PMCID: PMC10407786.
. CD4+ TIL to the rescue of anti-PD-1 failure by targeting MHC-II. Clin Cancer Res. 2023-10-02; doi: 10.1158/1078-0432.CCR-23-1333. PubMed PMID: 37534980; PMCID: PMC10592266.
. Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells. Sci Immunol. 2023-09-15;8(87):eadf6717. doi: 10.1126/sciimmunol.adf6717. PubMed PMID: 37713508; PMCID: PMC11045170.
. Debating Sentinel Lymph Node Biopsy for Melanoma in the Modern Adjuvant Era. J Clin Oncol. 2023-09-10;JCO2300255. doi: 10.1200/JCO.23.00255. PubMed PMID: 37410978; PMCID: PMC10852382.
. LAG-3 as the third checkpoint inhibitor. Nat Immunol. 2023-09-01;24(9):1415-1422. doi: 10.1038/s41590-023-01569-z. PubMed PMID: 37488429; PMCID: PMC11144386.
. PD-1 Monotherapy Reigns Supreme in Adjuvant Melanoma…But for How Long? Clin Cancer Res. 2023-09-01;29(17):3253-3255. doi: 10.1158/1078-0432.CCR-23-1194. PubMed PMID: 37378689; PMCID: PMC10527539.
. Amphiregulin couples IL1RL1(+) regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity. Sci Adv. 2023-08-25;9(34):eadd7399. doi: 10.1126/sciadv.add7399. PubMed PMID: 37611111; PMCID: PMC10446484.
. The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells. Immunity. 2023-08-08;56(8):1862-1875.e9. doi: 10.1016/j.immuni.2023.06.022. PubMed PMID: 37478853; PMCID: PMC10529081.
. Stability and heterogeneity in the antimicrobiota reactivity of human milk-derived immunoglobulin A. J Exp Med. 2023-08-07;220(8): doi: 10.1084/jem.20220839. PubMed PMID: 37462916; PMCID: PMC10354535.
. CD16+ Macrophages: An Emerging Biomarker for Combined CTLA-4 and PD-1 Blockade. Clin Cancer Res. 2023-07-05;29(13):2345-2347. doi: 10.1158/1078-0432.CCR-23-0490. PubMed PMID: 37097465; PMCID: PMC10330271.
. Phase I Study of SYNB1891, an Engineered E. coli Nissle Strain Expressing STING Agonist, with and without Atezolizumab in Advanced Malignancies. Clin Cancer Res. 2023-07-05;29(13):2435-2444. doi: 10.1158/1078-0432.CCR-23-0118. PubMed PMID: 37227176; PMCID: PMC11225568.
. Signaling is the pathway to macrophage function. Trends Immunol. 2023-07-01;44(7):496-498. doi: 10.1016/j.it.2023.04.007. PubMed PMID: 37258361; PMCID: PMC11460561.
. Screening for extranodal extension in HPV-associated oropharyngeal carcinoma: evaluation of a CT-based deep learning algorithm in patient data from a multicentre, randomised de-escalation trial. Lancet Digit Health. 2023-06-01;5(6):e360-e369. doi: 10.1016/S2589-7500(23)00046-8. PubMed PMID: 37087370; PMCID: PMC10245380.
. Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases. J Clin Invest. 2023-05-15;133(10): doi: 10.1172/JCI162260. PubMed PMID: 37183819; PMCID: PMC10178837.
. Phase I study of SYNB1891, an engineered E coli Nissle strain expressing STING agonist, with and without atezolizumab in advanced malignancies. Clin Cancer Res. 2023-05-09; doi: 10.1158/1078-0432.CCR-23-0118. PubMed PMID: 37159185.
. Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. J Exp Med. 2023-05-01;220(5): doi: 10.1084/jem.20221346. PubMed PMID: 36828389; PMCID: PMC9997508.
. Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing. JAMA Dermatol. 2023-05-01;159(5):545-553. doi: 10.1001/jamadermatol.2023.0127. PubMed PMID: 36920356; PMCID: PMC11225588.
. IFNγ-induction of T(H)1-like regulatory T cells controls antiviral responses. Nat Immunol. 2023-05-01;24(5):841-854. doi: 10.1038/s41590-023-01453-w. PubMed PMID: 36928412; PMCID: PMC10224582.
. Randomized, Double-Blind, Placebo-Controlled Trial of MUC1 Peptide Vaccine for Prevention of Recurrent Colorectal Adenoma. Clin Cancer Res. 2023-05-01;29(9):1678-1688. doi: 10.1158/1078-0432.CCR-22-3168. PubMed PMID: 36892581; PMCID: PMC10159922.
. Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment. Cell. 2023-04-27;186(9):1846-1862.e26. doi: 10.1016/j.cell.2023.03.011. PubMed PMID: 37028428; PMCID: PMC10148916.
. Myeloid Maturity: ATRA to Enhance Anti-PD-1? Clin Cancer Res. 2023-04-03;29(7):1167-1169. doi: 10.1158/1078-0432.CCR-22-3652. PubMed PMID: 36656164; PMCID: PMC10073251.
. Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment. Nat Cancer. 2023-04-01;4(4):516-534. doi: 10.1038/s43018-023-00527-w. PubMed PMID: 36927792; PMCID: PMC11194444.
. Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment. Nat Rev Cancer. 2023-03-01;23(3):173-188. doi: 10.1038/s41568-022-00531-9. PubMed PMID: 36456755; PMCID: PMC9992112.
. Interferon Biology and LAG-3 Shedding in PD-(L)1 plus LAG-3 Immunotherapy. Clin Cancer Res. 2023-03-01;29(5):835-837. doi: 10.1158/1078-0432.CCR-22-3312. PubMed PMID: 36534010; PMCID: PMC9992241.
. Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors. J Immunother Cancer. 2023-03-01;11(3): doi: 10.1136/jitc-2022-006522. PubMed PMID: 36914208; PMCID: PMC10016249.
. Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells. Immunity. 2023-02-14;56(2):369-385.e6. doi: 10.1016/j.immuni.2023.01.003. PubMed PMID: 36720219; PMCID: PMC10182785.
. Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity. Nat Immunol. 2023-02-01;24(2):267-279. doi: 10.1038/s41590-022-01379-9. PubMed PMID: 36543958; PMCID: PMC10402660.
. Old Dog, New Trick: A Tumor-Intrinsic Role for PD-1 in Chemoresistant Tumor Subclones. Clin Cancer Res. 2023-02-01;29(3):505-507. doi: 10.1158/1078-0432.CCR-22-3022. PubMed PMID: 36383142; PMCID: PMC9898080.
. Targeting Cbl-b in cancer immunotherapy. J Immunother Cancer. 2023-02-01;11(2): doi: 10.1136/jitc-2022-006007. PubMed PMID: 36750253; PMCID: PMC9906388.
. In memoriam: Soldano Ferrone, MD, PhD (1940-2023). J Immunother Cancer. 2023-01-30;11(1): doi: 10.1136/jitc-2023-006761. PubMed PMID: 36717185; PMCID: PMC9887713.
. Induction Exposure Dose of Ipilimumab and Failure of Adjuvant Nivolumab Plus Ipilimumab in Melanoma. J Clin Oncol. 2023-01-20;41(3):443-446. doi: 10.1200/JCO.22.01770. PubMed PMID: 36162010; PMCID: PMC9870232.
. Interferon Alfa-2b Adjuvant Therapy of High-Risk Resected Cutaneous Melanoma: The Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol. 2023-01-20;41(3):425-435. doi: 10.1200/JCO.22.02264. PubMed PMID: 36649675.
. Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134. J Clin Oncol. 2023-01-10;41(2):186-197. doi: 10.1200/JCO.22.01763. PubMed PMID: 36166727; PMCID: PMC9839305.
. The microbiota control the neonatal WNT-ernet. Immunity. 2022-12-13;55(12):2219-2222. doi: 10.1016/j.immuni.2022.11.005. PubMed PMID: 36516814; PMCID: PMC10165554.
. Microbiome-derived metabolites counteract tumor-induced immunosuppression and boost immune checkpoint blockade. Cell Metab. 2022-12-06;34(12):1903-1905. doi: 10.1016/j.cmet.2022.11.010. PubMed PMID: 36476933.
. Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy. Clin Cancer Res. 2022-12-01;28(23):5030-5039. doi: 10.1158/1078-0432.CCR-21-2390. PubMed PMID: 35579997; PMCID: PMC9669281.
. TGFβ(+) small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro-angiogenic phenotype. J Extracell Vesicles. 2022-12-01;11(12):e12294. doi: 10.1002/jev2.12294. PubMed PMID: 36537293; PMCID: PMC9764108.
. Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks. Clin Cancer Res. 2022-11-14;28(22):4968-4982. doi: 10.1158/1078-0432.CCR-22-1471. PubMed PMID: 36074145; PMCID: PMC9669190.
. Quantitative Spatial Profiling of TILs as the Next Step beyond PD-L1 Testing for Immune Checkpoint Blockade. Clin Cancer Res. 2022-11-14;28(22):4835-4837. doi: 10.1158/1078-0432.CCR-22-2277. PubMed PMID: 36103258; PMCID: PMC9669208.
. Hereditary Cancer Syndromes-A Broader Clinical Spectrum Than Previously Understood? JAMA Oncol. 2022-11-01;8(11):1698-1699. doi: 10.1001/jamaoncol.2022.3776. PubMed PMID: 36048458.
. The IL-1 family in tumorigenesis and antitumor immunity. Semin Cancer Biol. 2022-11-01;86(Pt 2):280-295. doi: 10.1016/j.semcancer.2022.05.002. PubMed PMID: 35580824.
. Therapeutic targeting of regulatory T cells in cancer. Trends Cancer. 2022-11-01;8(11):944-961. doi: 10.1016/j.trecan.2022.06.008. PubMed PMID: 35853825; PMCID: PMC9588644.
. A Druggable Rheostat for Ewing Sarcoma? Clin Cancer Res. 2022-10-14;28(20):4360-4362. doi: 10.1158/1078-0432.CCR-22-1794. PubMed PMID: 35921177; PMCID: PMC9588653.
. Facts and Hopes for Gut Microbiota Interventions in Cancer Immunotherapy. Clin Cancer Res. 2022-10-14;28(20):4370-4384. doi: 10.1158/1078-0432.CCR-21-1129. PubMed PMID: 35748749; PMCID: PMC9561605.
. A retrospective analysis of the impact of the COVID-19 pandemic on staging at presentation of patients with invasive melanoma. J Am Acad Dermatol. 2022-10-01;87(4):906-908. doi: 10.1016/j.jaad.2022.05.008. PubMed PMID: 35551967; PMCID: PMC9085439.
. Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus. Nat Immunol. 2022-10-01;23(10):1457-1469. doi: 10.1038/s41590-022-01310-2. PubMed PMID: 36151396; PMCID: PMC9561083.
. Autoantibodies as Predictors for Clinical Outcome and Toxicity for Immunotherapy. Clin Cancer Res. 2022-09-15;28(18):3914-3916. doi: 10.1158/1078-0432.CCR-22-1664. PubMed PMID: 36106401; PMCID: PMC9494631.
. Phase IB Study of GITR Agonist Antibody TRX518 Singly and in Combination with Gemcitabine, Pembrolizumab, or Nivolumab in Patients with Advanced Solid Tumors. Clin Cancer Res. 2022-09-15;28(18):3990-4002. doi: 10.1158/1078-0432.CCR-22-0339. PubMed PMID: 35499569; PMCID: PMC9475244.
. Team victory, yellow helmets for a computational tour de force. Cell. 2022-09-15;185(19):3459-3461. doi: 10.1016/j.cell.2022.08.013. PubMed PMID: 36113423; PMCID: PMC9805362.
. Adjuvant therapy in stage IIB and IIC melanoma: is sentinel biopsy needed? - Authors' reply. Lancet. 2022-08-20;400(10352):559-560. doi: 10.1016/S0140-6736(22)01350-2. PubMed PMID: 35988561.
. Neoadjuvant immunotherapy of locoregionally advanced solid tumors. J Immunother Cancer. 2022-08-01;10(8): doi: 10.1136/jitc-2022-005036. PubMed PMID: 35973745; PMCID: PMC9386211.
. Repetitive expanded T-cell receptor clonotypes impart the classic T helper 2 Sézary cell phenotype. Br J Dermatol. 2022-08-01;187(2):265-267. doi: 10.1111/bjd.21061. PubMed PMID: 35191024.
. Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022-07-13;30(7):1003-1019.e10. doi: 10.1016/j.chom.2022.05.006. PubMed PMID: 35658976; PMCID: PMC9841318.
. Optimal systemic therapy for high-risk resectable melanoma. Nat Rev Clin Oncol. 2022-07-01;19(7):431-439. doi: 10.1038/s41571-022-00630-4. PubMed PMID: 35468949; PMCID: PMC11075933.
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