New Pathogen Discovery
. Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases. Proc Natl Acad Sci U S A. 2023-12-19;120(51):e2316467120. doi: 10.1073/pnas.2316467120. PubMed PMID: 38079542; PMCID: PMC10740393.
. METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle. Cell Death Dis. 2023-09-06;14(9):591. doi: 10.1038/s41419-023-06121-3. PubMed PMID: 37673880; PMCID: PMC10482891.
. Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity. Proc Natl Acad Sci U S A. 2023-07-25;120(30):e2308010120. doi: 10.1073/pnas.2308010120. PubMed PMID: 37459531; PMCID: PMC10372695.
. Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp). J Med Virol. 2023-01-01;95(1):e28246. doi: 10.1002/jmv.28246. PubMed PMID: 36271490; PMCID: PMC9874566.
. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nat Commun. 2021-02-16;12(1):1055. doi: 10.1038/s41467-021-21206-3. PubMed PMID: 33594058; PMCID: PMC7887217.
. Proteomic approach to discover human cancer viruses from formalin-fixed tissues. JCI Insight. 2020-11-19;5(22): doi: 10.1172/jci.insight.143003. PubMed PMID: 33055416; PMCID: PMC7710300.
. Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. J Clin Invest. 2019-07-15;129(8):3310-3323. doi: 10.1172/JCI127166. PubMed PMID: 31305263; PMCID: PMC6668677.
. The conundrum of causality in tumor virology: the cases of KSHV and MCV. Semin Cancer Biol. 2014-06-01;264-12. doi: 10.1016/j.semcancer.2013.11.001. PubMed PMID: 24304907; PMCID: PMC4040341.