Journal Club
The focus of the Journal Club is to discuss the most exciting findings in women’s cancer research, report on related topics, and to stimulate interactions between basic, translational, and clinical researchers. The general theme will be translational research, discussing papers that give biological and mechanistic insight into clinical observations, with the goal of stimulating new thoughts on research programs in the WCRC.
Journal Club will return in the fall, please check back for dates.
Format: will be a 'round table discussion' with no slides...'presenters' will be more like discussion leaders giving a summary of the paper, explaining key points, and bringing prepared discussion points/questions to stimulate groups discussion.
Quick Links
Breast Cancer Translational Research Working Group
The purpose of the Breast Cancer Translational Research Group is to bring together our multidisciplinary group of researchers to increase collaboration and streamline research efficiency and productivity. The meeting is the first and third Wednesday of each month, and it is open to all members of the Women's Cancer Research Center and the Magee Women's Breast Center, as well as trainees within these groups. It is a great forum to improve communication between basic scientists and clinicians to maximize study potential - both by understanding the clinical underpinnings of our bench work and to incorporate basic science correlates into our clinical studies. Here we identify research obstacles, troubleshoot problems, get feedback about new ideas and concepts, practice research short talks prior to presentation at national meetings and share successes. Our goal is to increase our initiation of, accrual to and completion of our home-grown clinical trials.
The following poster templates are for the Breast Cancer Translational Research Working Group poster presentation.
External Work-in-progress (WIP)
The goal of WIP is to provide a forum for investigators (trainees, students, fellows, junior faculty) to discuss their research in a multi-disciplinary setting.
Time: The first Thursday of every month, 10:30-11:30 am
Place: MWRI-1st Floor Conference Room
2017 Work-in-progress
| Past Speakers / Affliliation | Date of Seminar |
| Jorge Reis-Filho, MD, PhD, Physician-sicentist, Memorial Sloan Kettering Cancer Center - Genetic analysis of rare forms of triple-negative breast cancer: more than tumor philately | 1/5/2017 |
| Faina Linkov, Associate Professor, University of Pittsburgh School of Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, Magee-Womens Research Institute - Novel and existing research directions in the field of endometrial cancer | 2/2/2017 |
| Dr. Xin Huang, Assistant Professor, Department of Obstetrics, Gynecology & Reproductive Sciences, Division of Gynecological Oncology, University of Pittsburgh - Non-coding RNA regulation of the hypoxic pathway | 3/2/2017 |
| Aleks Rajkovic, MD, PhD, Professor and Marcus Allen Hogge Chair in Reproductive Sciences, Director of Reproductive Genetics, Department of Obstetrics, Gynecology and Reproductive Sciences - Genetic Underpinnings of Leiomyoma | 4/6/2017 |
| Malcolm Ross and Erin Harnett, Gynecologic Oncology Fellow, University of Pittsburgh | 6/8/2017 |
2016 Work-in-progress Archive
| Past Speakers / Affliliation | Date of Seminar |
| Da Yang, PhD, Physician-sicentist, Memorial Sloan Kettering Cancer Center | 12/1/2016 |
| Yang Liu, PhD, Assistant Professor of Pharmaceutical Sciences, University of Pittsburgh Cancer Instittute | 11/3/2016 |
| Lewis Chodosh, MD, PhD, Professor and Chair Associate Director for Basic Science, Abramson Cancer Center Director, Cancer Genetics, Abramson Family Cancer Research Institute | 10/6/2016 |
| Fellows (Shannon Grabosch, MD and Casey Hay, MD) | 6/2/2016 |
| Richard Steinman, MD PhD, New approaches to the microenvironment in breast cancer cellular dormancy and metastasis | 5/5/2016 |
| Karen Lu, MD, Phd, Chair, Department of Gynecologic Oncology and Reproductive Medicine, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX | 4/7/2016 |
| Madhavi Kumari Ganapathiraju, PhD, Assistant Professor, Department of Biomedical Informatics, University of Pittsburgh | 3/3/2016 |
| Xinghua Lu, PhD, Associate Professor, Department of Biomedical Informatics, University of Pittsburgh | 2/4/2016 |
| Binfeng Lu, PhD, Associate Professor, Department of Immunology, University of Pittsburgh | 1/7/2016 |
2015 Work-in-progress Archive
| Past Speakers / Affliliation | Date of Seminar |
| Fellows (Shannon Grabosch and Casey Hay) | 12/3/2015 |
| Ann Ramsdell, PhD, Associate Professor, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine | 11/5/2015 |
| Susan Domchek, MD, Basser Professor in Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania | 10/1/2015 |
| Shilpa Sant, PhD, Assistant Professor, School of Pharmacy, Department of Pharmaceutical Sciences, Department of Bioengineering, McGowan Institute for Regenerative Medicine, University of Pittsburgh | 9/3/2015 |
| Summer Break | 8/6/2015 |
| Summer Break | 7/2/2015 |
| Fellows | 6/4/2015 |
| Fariba Behbod, PhD, Associate Professor, Department of Pathology and Laboratory, University of Kansas School of Medicine, 3901 Rainbow Blvd. WHE 1005B | 5/7/2015 |
| Analisa Difeo, PhD, Assistant Professor, General Medical Sciences (Oncology), Norma C. and Albert I. Geller Designated Professor of Ovarian Cancer Research, Case Comprehensive Cancer Center, Case Western Reserve University | 4/2/2015 |
| Jianhua Xing, PhD, Visiting Associate Professor, Department of Computational & Systems Biology, School of Medicine, University of Pittsburgh | 3/12/2015 |
| Yang Liu, PhD, Associate Professor, Department of Medicine, Department of Bioengineering, University of Pittsburgh | 3/5/2015 |
| Kandace McGuire, MD, Assistant Professor of Surgery, University of Pittsburgh | 2/12/2015 |
2014 Work-in-progress Archive
| Past Speakers / Affliliation | Date of Seminar |
| Dr. Adam Brufsky Professor of Medicine Associate Chief, Division of Hematology/Oncology Co-Director, Comprehensive Breast Cancer Center Associate Director, Clinical Investigation |
12/4/14 |
| Fellows (Ob/Gyn) | 11/6/14 |
| Shandong Wu Research Assistant Professor, Imaging Research Center Radiology, School of Medicine, University of Pittsburgh |
10/2/14 |
| Joanna Burdette Associate Professor,Department of Medicinal Chemistry and Pharmacognosy and the Center of Pharmaceutical Biotechnology, University of Illinois at Chicago Topic: "The impact of ovulation on fallopian tube epithelial cells and high-grade serous cancer" |
9/4/14 |
| Hansen & Berger Fellows (Ob/Gyn) |
6/5/14 |
| Song Li, PhD Professor, Department of Pharmaceutical Sciences, University of Pittsburgh |
5/1/2014 |
| Sohrab Shah, PhD Assistant Professor, Depts of Pathology and Computer Science, University of British Columbia |
4/3/2014 |
| Charles N. Landen, Jr., MD, MS Dept. of Obstetrics & Gynecology, Division of Gynecologic Oncology University of Alabama at Birmingham, AL Topic: "Development of the patident-derived xenograft model to identifymediators of chemotherapy resistance in ovarian cancer" |
3/6/2014 |
| McAllister-Lucas, Linda, MD, PhD Chief, Division of Pediatric Hematology/Oncology, Assoc. Prof, Dept of Pediatrics Univ. of Pgh. School of Medicine Lucas, Peter, MD, PhD |
1/30/2014 |
| Mai, Phuong, MD, MS Genetice Candidate, Staff Physician, National Cancer Institute, Rockville, Maryland Topic: "Hereditary Cancer Risk Management - Strategies and Challenges" |
1/23/2014 |
| Lee, Byeong-Chel, PhD UPCI - Assistant Professor of Medicine Topic: "Heregulin-C/EBP beta CXCR4 axis in breast cancer progression and Metastasis" |
1/9/2014 |
2013 Work-in-progress Archive
| Past Speakers / Affliliation | Date of Seminar |
| Margaret Quinn Rosenzweig, PhD, FNP-BC, AOCNP Assoc. Professor of Oncology Focus, Acute Care Nurse Practitioner Program, Univ. of Pittsburgh School of Nursing Topic: "A longitudinal Analysis of Women with Metastatic Breast Cancer: Past, Present & Future" |
12/19/2013 |
| Andrew Stern, PhD Director of Novel Therapeutics, Univesity of Pittsburgh Drug Discovery Institute Topic: "Identifying cancer cell dependencies and targeting them with repurposed drugs" |
12/5/2013 |
| John Bartlett Professor, Program Director, Transformative Pathology, Ontario Institute for Cancer Research (OICR) Topic: "Predicting anthracycline response in breast cancer - have we finally arrived" |
12/3/2013 |
| Anna Lokshin, PhD Prof. of Medicine, Pathology & OB/Gyn/RS, Director Luminex Core Facility, Hillman Cancer Center Topic: "Urine biomarkers in cancer" |
11/21/2013 |
| David Boone, PhD Postdoc in Adrian Lee's Lab Topic: "SNHG7 is an IGF1 regulated lincRNA necessary for full proliferation of MCF7 breast cancer epithelial cells" |
11/14/2013 |
| Rachel Schiff, PhD Assoc. Prof., Dept of Medicine-Hematology/Oncology, Smith Breast Center, Baylor College of Medicine, Houston, TX Topic: "Breast Cancer HER2-targeted therapy and mechanisms of resistance" |
10/31/2013 |
| Jessica Berger, MD Gyn/Onc Fellow/Dr.Kyle Orwig's Lab Topic: "Preventing chemotherapy-induced dysfunction in an early stafe ovarian cancer model" |
10/24/2013 |
| Karyn Hansen, MD Gyn/Onc Fellow/Dr. Ben Van Houten's Lab Topic: "Ovarian cancer cells demonstrate metabolic flexibility by utilizing fatty acid beta oxidation" |
10/24/2013 |
| H. Michael Gach Assoc. Prof. of Radiology & Bioengineering, Hillman/University of Pitt. Topic: "MRI & PET/MRI in translational Research of How I Learned to Love Ovarian Cancer" |
10/17/2013 |
| Tiffany Katz, PhD Postdoc/Research Associate, Hillman Topic: "Histone Lysine Specific Demethylase 2 (LSD2)" |
10/10/2013 |
| Andrea Jeanne Berman, PhD Asst Prof/Dept. of Biological Sciences, Univ. of Pgh. Topic: "La-related Protein 1: a new player in ovarian cancer" |
9/26/2013 |
| Jesus Gonzalez Bosquet, PhD Gyn/Oncology Dept. at Moffitt Cancer & Research Institute Topic: "Analysis of Ovarian Cancer Chemo-response using publcly available high-throughput data" |
8/8/2013 |
| Sanaz Memarzadeh, MD, PhD Assist. Prof., Dept. of Obstetrics & Gyn, The David Geffen School of Medicine at UCLA Topic: "Signaling through the progesterone receptor in the tumor microenvironment is a key regulator of resonse to hormonal therapy" |
6/6/2013 |
| Xinghua Lu, MD, PhD Associate Professor, Dept. of Biomedical informatics, Univ. of Pgh. Topic: "Identify Informative Modular Features for Predicting Cancer Clinical Outcomes" |
5/30/2013 |
| Lesley Butler, PhD Assoc. Prof. Univ. of Pgh.. Cancer Institute, UPMC Cancer Pavilion Topic: "Urinary biomarkers of angiogenesis and breast cancer risk |
5/23/2013 |
| Jeff Lin, MD Gyn/Onc fellow in Huang's Lab Topic: "Distinct Expression of MicroRNA in Ovarian Cancer Ascites" |
5/16/2013 |
| Sarah Taylor, MD Gyn/Onc Fellow in Lee's Lab Topic: "IGF-1 Pathway as a potential Therapeutic target in Epithelial Ovarian Cancer" |
5/16/2013 |
| Adrian Lee, PHD Prof., Dept. of Pharmacology & Chem. Biology, Dir. Women's Cancer Institute Topic: "Intra-tumor heterogeneity & personalized medicine: Studies ongoing at the WCRC" |
5/9/2013 |
| Amir Bahreini, BSC Graduate Student in Dr. Oesterreich's Lab Topic: "The Identification of DNA Sequence Variants in Estrogen Receptor Binding Sites in Greast Cancer" |
5/2/2013 |
| Jorge Rios, Fellow Div. of Hematology-Oncology, University of Pgh. Institute (Lee's Lab) Topic: "Bone metastasis in breast cancer: Association between clinical outcomes and molecular characteristics of the primary tumors and their metastasis" |
5/2/2013 |
| Terence McGuire, PhD Candidate for Non-Tenured Researcher Topic: "Tumor-Derived Endothelium: In Vivo Evolution and In Vitro Recapitulation" |
4/18/2013 |
| Xin Huang, PhD Research Asst. Professor, Department of Pharmacology & Chemical Biology, The Hillman Cancer Center Topic: "Targeting histone lysine demethylases in breast cancer therapy" |
4/11/2013 |
| Linwah Yip, MD Assistant Professor of Surgery, Division of Endocrine Surgery Topic: "Molecular Markers in Thyroid Cancer" |
4/4/2013 |
| Mei Zhang, PhD Asst. Prof, Department of Developmental Biology Topic: "Breast Cancer stem cells and their progeny" |
3/21/2013 |
| Otto Metzge, MD Research Fellow in Medicine, Breast Oncology Center, Dana Farber Cancer Institute, Boston Topic: "New frontiers in the treatment of Invasive Lobular Carcinoma" |
3/14/2013 |
| Li Lan, MD, PhD Asst. Prof, Dept of Microbiology & Molecular Genetics, Univ. of Pgh., Hillman Cancer Center Topic: "DNS repair and chromatin remodeling and their relationship to genome instability: in situ analysis of DNA damage responses" |
3/7/2013 |
| Vera Donnenberg, PhD, FCP Associate Prof. of Cardiothoracic Surgery & Pharmaceutical Sciences, Hillman Cancer Center Topic: "Breast Cancer Stem Cells: a decade later" |
2/28/2013 |
| Steffi Oesterreich, PhD Prof, Dept. of Pharmacology & Chemical Biology, Co-Leader Molecular & Cellular cancer Biology Program, Univ. of Pgh., Cancer Institute & Dir. Of Education at the Women's Cancer Research Center Topic: MWRI Methylation-age BRCA |
2/21/2013 |
| Xin Huang, PhD Asst. Prof., Gyn/Onc. Magee Women's Research Institute Topic: "MicroRNA expression profiling in endometriosis and endometriosis-associated ovarian cancer" |
2/7/2013 |
| Anda Vlad, MD, PhD Asst Prof. Dept. of Obstetrics, Gyn & Repro Sciences, Univ. of Pgh, School of Medicine, Magee Topic: Immune dysregulatio in endometriosis and ovarian cancer |
1/31/2013 |
| Chandra Batula, PhD Dr. Lee's Lab Topic: "Targeting IGF-IR as a Therapeutic approach for triple negative breast cancer" |
1/24/2013 |
| Faina Linkov, PhD, MPH Asst. Prof, Research Division Topci: "Decision support systems for obese gynecologic onc patients: Funding opportunities through PCORI" |
1/17/2013 |
| Per Basse, MD, PhD, DMSci Assoc. Prof. of Immunology, UPCI at the Hillman Cancer Center Topic: "Immunology of Breast Cancer Brain Metastases" |
1/10/2013 |
2012 Work-in-progress Archive
| Past Speakers | Affiliation | Seminar | Date of Seminar |
| Orla Conneely | Baylor College of Medicine, Houston TX | 11/6/2012 | |
| Suzanne Conzen | University of Chicago | 11/14/2012 | |
| Jennifer K. Richer, Ph.D. | Associate Professor, Department of Pathology, University of Colorado Anschutz Medical Campus |
The Androgen Receptor in Breast Cancer - Novel Insights | 10/4/2012 |
| Bryan Welm | Huntsman Cancer Institute, Salt Lake City Utah | WCRC WIP | 5/22/2012 |
| Alana Welm | Huntsman Cancer Institute, Salt Lake City Utah | UPCI - Basic & Translational | 5/22/2012 |
| Carola Neumann, MD | Medical University of South Carolina | PCB | 5/1/2012 |
2011 Work-in-progress Archive
| Past Speakers | Affiliation | Seminar | Date of Seminar |
| David Huntsman | British Columbia Cancer Agency, Vancouver, BC, Canada | WCRC WIP | 10/26/2011 |
| Aleks Milosevich | Baylor College of Medicine, Houston TX | WCRC special seminar | 10/25/2011 |
| Mitch Dowsett | Royal Marsden, London, UK | WCRC special seminar | 10/24/2011 |
| Powel Brown | The University of Texas, MD Anderson Cancer Center | UPCI - Basic & Translational | 9/13/2011 |
| Paul Haluska, MD, PhD | Mayo Clinic, Rochester MN | WCRC WIP | 9/8/2011 |
| Kenneth Nephew | Simon Cancer Center, Indiana University | UPCI - Basic & Translational | 5/31/2011 |
| Matthew Ellis, PhD | Washington University, St. Louis, MO | 1st Annual WCRC Retreat | 5/6/2011 |
| Carol Lange, PhD | Masonic Cancer Center, University of Minnesota | WCRC WIP | 4/26/2011 |
