Member Publications

Wegner RE, Leeman JE, Kabolizadeh P, Rwigema JC, Mintz AH, Burton SA, Heron DE. Fractionated stereotactic radiosurgery for large brain metastases. Am J Clin Oncol. 2015 Apr;38(2):135-9. doi: 10.1097/COC.0b013e31828aadac. PubMed PMID: 23563213.
Pollock SL, Rush EA, Redner RL. NPM-RAR, not the RAR-NPM reciprocal t(5;17)(q35;q21) acute promyelocytic leukemia fusion protein, inhibits myeloid differentiation. Leuk Lymphoma. 2014 Jun;55(6):1383-7. doi: 10.3109/10428194.2013.830303. PubMed PMID: 23927396.
Vargo JA, Heron DE, Ferris RL, Rwigema JC, Kalash R, Wegner RE, Ohr J, Burton S. Examining tumor control and toxicity after stereotactic body radiotherapy in locally recurrent previously irradiated head and neck cancers: implications of treatment duration and tumor volume. Head Neck. 2014 Sep;36(9):1349-55. doi: 10.1002/hed.23462. PubMed PMID: 24038398.
Kabolizadeh P, Kalash R, Huq MS, Greenberger JS, Heron DE, Beriwal S. Dosimetric definitions of total lung volumes in calculating parameters predictive for radiation-induced pneumonitis. Am J Clin Oncol. 2015 Aug;38(4):401-4. doi: 10.1097/COC.0b013e3182a2588f. PubMed PMID: 24064747.
Vargo JA, Kubicek GJ, Ferris RL, Duvvuri U, Johnson JT, Ohr J, Clump DA, Burton S, Heron DE. Adjuvant stereotactic body radiotherapy±cetuximab following salvage surgery in previously irradiated head and neck cancer. Laryngoscope. 2014 Jul;124(7):1579-84. doi: 10.1002/lary.24441. PubMed PMID: 24123056.
Lim CM, Gilbert MR, Johnson JT, Kim S. Clinical significance of intraparotid lymph node metastasis in primary parotid cancer. Head Neck. 2014 Nov;36(11):1634-7. doi: 10.1002/hed.23507. PubMed PMID: 24123567.
Maxwell JH, Mehta V, Wang H, Cunningham D, Duvvuri U, Kim S, Johnson JT, Ferris RL. Quality of life in head and neck cancer patients: impact of HPV and primary treatment modality. Laryngoscope. 2014 Jul;124(7):1592-7. doi: 10.1002/lary.24508. PubMed PMID: 24353066.
Oborski MJ, Demirci E, Laymon CM, Lieberman FS, Mountz JM. Assessment of early therapy response with 18F-FLT PET in glioblastoma multiforme. Clin Nucl Med. 2014 Oct;39(10):e431-2. doi: 10.1097/RLU.0000000000000321. PubMed PMID: 24368529.
Wang J, Dai S, Guo Y, Xie W, Zhai Y. Biology of PXR: role in drug-hormone interactions. EXCLI J. 2014;13728-39. PubMed PMID: 26417296; PMCID: PMC4464432.
Wang C, Kundaria S, Fernandez-Miranda J, Duvvuri U. A description of arterial variants in the transoral approach to the parapharyngeal space. Clin Anat. 2014 Oct;27(7):1016-22. doi: 10.1002/ca.22273. PubMed PMID: 24510490.
Byrd JK, Smith KJ, de Almeida JR, Albergotti WG, Davis KS, Kim SW, Johnson JT, Ferris RL, Duvvuri U. Transoral Robotic Surgery and the Unknown Primary: A Cost-Effectiveness Analysis. Otolaryngol Head Neck Surg. 2014 Jun;150(6):976-82. doi: 10.1177/0194599814525746. PubMed PMID: 24618502; PMCID: PMC4167971.
Zhou P, Huang G, Zhao Y, Zhong D, Xu Z, Zeng Y, Zhang Y, Li S, He F. MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells. Cell Signal. 2014 Jun;26(6):1347-54. doi: 10.1016/j.cellsig.2014.02.020. PubMed PMID: 24631531.
Leonardis RL, Duvvuri U, Mehta D. Transoral robotic-assisted laryngeal cleft repair in the pediatric patient. Laryngoscope. 2014 Sep;124(9):2167-9. doi: 10.1002/lary.24680. PubMed PMID: 24648210.
Lim CM, Hobson C, Kim S, Johnson JT. Clinical outcome of patients with carcinoma ex pleomorphic adenoma of the parotid gland: a comparative study from a single tertiary center. Head Neck. 2015 Apr;37(4):543-7. doi: 10.1002/hed.23638. PubMed PMID: 24677516.
Zhang Y, Huang Y, Li S. Polymeric micelles: nanocarriers for cancer-targeted drug delivery. AAPS PharmSciTech. 2014 Aug;15(4):862-71. doi: 10.1208/s12249-014-0113-z. PubMed PMID: 24700296; PMCID: PMC4113619.
Gross ND, Bauman JE, Gooding WE, Denq W, Thomas SM, Wang L, Chiosea S, Hood BL, Flint MS, Sun M, Conrads TP, Ferris RL, Johnson JT, Kim S, Argiris A, Wirth L, Nikiforova MN, Siegfried JM, Grandis JR. Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer. Clin Cancer Res. 2014 Jun 15;20(12):3289-98. doi: 10.1158/1078-0432.CCR-13-3360. PubMed PMID: 24727329; PMCID: PMC4104657.
Byrd JK, Leonardis RL, Bonawitz SC, Losee JE, Duvvuri U. Transoral robotic surgery for pharyngeal stenosis. Int J Med Robot. 2014 Dec;10(4):418-22. doi: 10.1002/rcs.1591. PubMed PMID: 24737499.
Jane EP, Premkumar DR, Morales A, Foster KA, Pollack IF. Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells. J Pharmacol Exp Ther. 2014 Jul;350(1):22-35. doi: 10.1124/jpet.114.212910. PubMed PMID: 24741074; PMCID: PMC4056270.
Zhong L, Yang Q, Xie W, Zhou J. Liver X receptor regulates mouse GM-CSF-derived dendritic cell differentiation in vitro. Mol Immunol. 2014 Jul;60(1):32-43. doi: 10.1016/j.molimm.2014.03.006. PubMed PMID: 24747959.
Karunamurthy A, Cai G, Dacic S, Khalbuss WE, Pantanowitz L, Monaco SE. Reply to verification bias in diagnostic accuracy studies for fine-needle aspiration cytology. Cancer Cytopathol. 2014 Jun;122(6):474-5. doi: 10.1002/cncy.21432. PubMed PMID: 24753510.
Bale SS, Vernetti L, Senutovitch N, Jindal R, Hegde M, Gough A, McCarty WJ, Bakan A, Bhushan A, Shun TY, Golberg I, DeBiasio R, Usta BO, Taylor DL, Yarmush ML. In vitro platforms for evaluating liver toxicity. Exp Biol Med (Maywood). 2014 Sep;239(9):1180-1191. doi: 10.1177/1535370214531872. PubMed PMID: 24764241; PMCID: PMC4156546.
Lee JJ, Chu E. Sequencing of antiangiogenic agents in the treatment of metastatic colorectal cancer. Clin Colorectal Cancer. 2014 Sep;13(3):135-44. doi: 10.1016/j.clcc.2014.02.001. PubMed PMID: 24768040.
O'Connell MJ, Colangelo LH, Beart RW, Petrelli NJ, Allegra CJ, Sharif S, Pitot HC, Shields AF, Landry JC, Ryan DP, Parda DS, Mohiuddin M, Arora A, Evans LS, Bahary N, Soori GS, Eakle J, Robertson JM, Moore DF Jr, Mullane MR, Marchello BT, Ward PJ, Wozniak TF, Roh MS, Yothers G, Wolmark N. Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04. J Clin Oncol. 2014 Jun 20;32(18):1927-34. doi: 10.1200/JCO.2013.53.7753. PubMed PMID: 24799484; PMCID: PMC4050205.
Davis KS, Byrd JK, Mehta V, Chiosea SI, Kim S, Ferris RL, Johnson JT, Duvvuri U. Occult Primary Head and Neck Squamous Cell Carcinoma: Utility of Discovering Primary Lesions. Otolaryngol Head Neck Surg. 2014 Aug;151(2):272-8. doi: 10.1177/0194599814533494. PubMed PMID: 24812081; PMCID: PMC4604041.
Choueiri TK, Jacobus S, Bellmunt J, Qu A, Appleman LJ, Tretter C, Bubley GJ, Stack EC, Signoretti S, Walsh M, Steele G, Hirsch M, Sweeney CJ, Taplin ME, Kibel AS, Krajewski KM, Kantoff PW, Ross RW, Rosenberg JE. Neoadjuvant dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin with pegfilgrastim support in muscle-invasive urothelial cancer: pathologic, radiologic, and biomarker correlates. J Clin Oncol. 2014 Jun 20;32(18):1889-94. doi: 10.1200/JCO.2013.52.4785. PubMed PMID: 24821883.
Baker AS, Deiters A. Optical control of protein function through unnatural amino acid mutagenesis and other optogenetic approaches. ACS Chem Biol. 2014 Jul 18;9(7):1398-407. doi: 10.1021/cb500176x. PubMed PMID: 24819585.
Mathew A, Brufsky A. Bisphosphonates in breast cancer. Int J Cancer. 2015 Aug 15;137(4):753-64. doi: 10.1002/ijc.28965. PubMed PMID: 24824552.
Solomon JD, Heitzer MD, Liu TT, Beumer JH, Parise RA, Normolle DP, Leach DA, Buchanan G, DeFranco DB. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol Cancer Res. 2014 Aug;12(8):1166-80. doi: 10.1158/1541-7786.MCR-13-0395. PubMed PMID: 24825850; PMCID: PMC4134986.
Wang P, Han L, Shen H, Wang P, Lv C, Zhao G, Niu J, Xue L, Wang QJ, Tong T, Chen J. Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammation. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7683-8. doi: 10.1073/pnas.1310972111. PubMed PMID: 24828530; PMCID: PMC4040603.
DeCaprio JA, Duensing A. The DREAM complex in antitumor activity of imatinib mesylate in gastrointestinal stromal tumors. Curr Opin Oncol. 2014 Jul;26(4):415-21. doi: 10.1097/CCO.0000000000000090. PubMed PMID: 24840522; PMCID: PMC4236229.
Pillai VC, Parise RA, Christner SM, Rudek MA, Beumer JH, Venkataramanan R. Potential interactions between HIV drugs, ritonavir and efavirenz and anticancer drug, nilotinib--a study in primary cultures of human hepatocytes that is applicable to HIV patients with cancer. J Clin Pharmacol. 2014 Nov;54(11):1272-9. doi: 10.1002/jcph.333. PubMed PMID: 24846165.
Brufsky AM. Predictive and prognostic value of the 21-gene recurrence score in hormone receptor-positive, node-positive breast cancer. Am J Clin Oncol. 2014 Aug;37(4):404-10. doi: 10.1097/COC.0000000000000086. PubMed PMID: 24853663; PMCID: PMC4162320.
Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. PubMed PMID: 24856103; PMCID: PMC4102141.
Geskin LJ, Akilov OE, Lin Y, Lokshin AE. Distinct age-matched serum biomarker profiles in patients with cutaneous T-cell lymphoma. Exp Dermatol. 2014 Aug;23(8):598-600. doi: 10.1111/exd.12455. PubMed PMID: 24862743; PMCID: PMC4125529.
Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD, LIFE study investigators.. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014 Jun 18;311(23):2387-96. doi: 10.1001/jama.2014.5616. PubMed PMID: 24866862; PMCID: PMC4266388.
Korotchenko VN, Saydmohammed M, Vollmer LL, Bakan A, Sheetz K, Debiec KT, Greene KA, Agliori CS, Bahar I, Day BW, Vogt A, Tsang M. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45. doi: 10.1002/cbic.201402000. PubMed PMID: 24909879; PMCID: PMC4118675.
Feng R, Milcarek CA, Xie XQ. Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion. BMC Pharmacol Toxicol. 2014 Jun 9;1530. doi: 10.1186/2050-6511-15-30. PubMed PMID: 24913620; PMCID: PMC4062519.
Shiwarski DJ, Shao C, Bill A, Kim J, Xiao D, Bertrand CA, Seethala RS, Sano D, Myers JN, Ha P, Grandis J, Gaither LA, Puthenveedu MA, Duvvuri U. To "grow" or "go": TMEM16A expression as a switch between tumor growth and metastasis in SCCHN. Clin Cancer Res. 2014 Sep 1;20(17):4673-88. doi: 10.1158/1078-0432.CCR-14-0363. PubMed PMID: 24919570; PMCID: PMC4160843.
Berhane H, Shinde A, Kalash R, Xu K, Epperly MW, Goff J, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Li S, Gao X, Greenberger JS. Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039. Radiat Res. 2014 Jul;182(1):35-49. doi: 10.1667/RR13633.1. PubMed PMID: 24932534; PMCID: PMC4101533.
Dorritie KA, Redner RL, Johnson DE. STAT transcription factors in normal and cancer stem cells. Adv Biol Regul. 2014 Sep;5630-44. doi: 10.1016/j.jbior.2014.05.004. PubMed PMID: 24931719.
Qian W, Wang J, Roginskaya V, McDermott LA, Edwards RP, Stolz DB, Llambi F, Green DR, Van Houten B. Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells. Oncotarget. 2014 Jun 30;5(12):4180-94. doi: 10.18632/oncotarget.1944. PubMed PMID: 24952704; PMCID: PMC4147315.
Parikh RA, Wang P, Beumer JH, Chu E, Appleman LJ. The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment. Onco Targets Ther. 2014;7969-83. doi: 10.2147/OTT.S40241. PubMed PMID: 24959084; PMCID: PMC4061161.
Lim CM, Gilbert M, Johnson JT, Kim S. Is level V neck dissection necessary in primary parotid cancer? Laryngoscope. 2015 Jan;125(1):118-21. doi: 10.1002/lary.24772. PubMed PMID: 24965707.
Vaz Fragoso CA, Hsu FC, Brinkley T, Church T, Liu CK, Manini T, Newman AB, Stafford RS, McDermott MM, Gill TM, LIFE Study Group.. Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. J Am Med Dir Assoc. 2014 Sep;15(9):665-70. doi: 10.1016/j.jamda.2014.05.008. PubMed PMID: 24973990; PMCID: PMC4145029.
Cai Z, Ouyang Q, Zeng D, Nguyen KN, Modi J, Wang L, White AG, Rogers BE, Xie XQ, Anderson CJ. 64Cu-labeled somatostatin analogues conjugated with cross-bridged phosphonate-based chelators via strain-promoted click chemistry for PET imaging: in silico through in vivo studies. J Med Chem. 2014 Jul 24;57(14):6019-29. doi: 10.1021/jm500416f. PubMed PMID: 24983404; PMCID: PMC4261236.
Landreneau RJ, Normolle DP, Christie NA, Awais O, Wizorek JJ, Abbas G, Pennathur A, Shende M, Weksler B, Luketich JD, Schuchert MJ. Recurrence and survival outcomes after anatomic segmentectomy versus lobectomy for clinical stage I non-small-cell lung cancer: a propensity-matched analysis. J Clin Oncol. 2014 Aug 10;32(23):2449-55. doi: 10.1200/JCO.2013.50.8762. PubMed PMID: 24982447; PMCID: PMC4121502.
Shinde A, Epperly MW, Cao S, Franicola D, Shields D, Wang H, Wipf P, Sprachman MM, Greenberger JS. Effects of the bifunctional sulfoxide MMS350, a radiation mitigator, on hematopoiesis in long-term bone marrow cultures and on radioresistance of marrow stromal cell lines. In Vivo. 2014 Jul-Aug;28(4):457-65. PubMed PMID: 24982210.
Epperly MW, Goff JP, Franicola D, Wang H, Wipf P, Li S, Greenberger JS. Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors. In Vivo. 2014 Jul-Aug;28(4):435-40. PubMed PMID: 24982207; PMCID: PMC6436097.
Fernando HC, Landreneau RJ, Mandrekar SJ, Nichols FC, Hillman SL, Heron DE, Meyers BF, DiPetrillo TA, Jones DR, Starnes SL, Tan AD, Daly BD, Putnam JB Jr. Impact of brachytherapy on local recurrence rates after sublobar resection: results from ACOSOG Z4032 (Alliance), a phase III randomized trial for high-risk operable non-small-cell lung cancer. J Clin Oncol. 2014 Aug 10;32(23):2456-62. doi: 10.1200/JCO.2013.53.4115. PubMed PMID: 24982457; PMCID: PMC4121503.
Ling DC, Kabolizadeh P, Heron DE, Ohr JP, Wang H, Johnson J, Kubicek GJ. Incidence of hospitalization in patients with head and neck cancer treated with intensity-modulated radiation therapy. Head Neck. 2015 Dec;37(12):1750-5. doi: 10.1002/hed.23821. PubMed PMID: 24986324.
Michalski D, Huq MS, Bednarz G, Heron DE. The use of strain tensor to estimate thoracic tumors deformation. Med Phys. 2014 Jul;41(7):073503. doi: 10.1118/1.4884222. PubMed PMID: 24989417.
Zhang X, Huang Y, Zhao W, Chen Y, Zhang P, Li J, Venkataramanan R, Li S. PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel. Mol Pharm. 2014 Aug 4;11(8):2807-14. doi: 10.1021/mp500181x. PubMed PMID: 24987803; PMCID: PMC4123940.
Tarr TB, Lacomis D, Reddel SW, Liang M, Valdomir G, Frasso M, Wipf P, Meriney SD. Complete reversal of Lambert-Eaton myasthenic syndrome synaptic impairment by the combined use of a K+ channel blocker and a Ca2+ channel agonist. J Physiol. 2014 Aug 15;592(16):3687-96. doi: 10.1113/jphysiol.2014.276493. PubMed PMID: 25015919; PMCID: PMC4229355.
Hartman DJ, Binion D, Regueiro M, Schraut W, Bahary N, Sun W, Nikiforova M, Pai RK. Isocitrate dehydrogenase-1 is mutated in inflammatory bowel disease-associated intestinal adenocarcinoma with low-grade tubuloglandular histology but not in sporadic intestinal adenocarcinoma. Am J Surg Pathol. 2014 Aug;38(8):1147-56. doi: 10.1097/PAS.0000000000000239. PubMed PMID: 25029120.
Ou Z, Jiang M, Hu B, Huang Y, Xu M, Ren S, Li S, Liu S, Xie W, Huang M. Transcriptional regulation of human hydroxysteroid sulfotransferase SULT2A1 by LXRα. Drug Metab Dispos. 2014 Oct;42(10):1684-9. doi: 10.1124/dmd.114.058479. PubMed PMID: 25028566; PMCID: PMC4164974.
Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery. PLoS One. 2014;9(7):e102678. doi: 10.1371/journal.pone.0102678. PubMed PMID: 25036749; PMCID: PMC4103836.
Diego EJ, Soran A, McGuire KP, Costellic C, Johnson RR, Bonaventura M, Ahrendt GM, McAuliffe PF. Localizing high-risk lesions for excisional breast biopsy: a comparison between radioactive seed localization and wire localization. Ann Surg Oncol. 2014 Oct;21(10):3268-72. doi: 10.1245/s10434-014-3912-2. PubMed PMID: 25034818.
Chattopadhyay A, Hood BL, Conrads TP, Redner RL. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD. Mol Cancer Res. 2014 Sep;12(9):1283-91. doi: 10.1158/1541-7786.MCR-14-0080. PubMed PMID: 25033841; PMCID: PMC4163521.
Qian Y, Panigrahy A, Laymon CM, Lee VK, Drappatz J, Lieberman FS, Boada FE, Mountz JM. Short-T2 imaging for quantifying concentration of sodium (23 Na) of bi-exponential T2 relaxation. Magn Reson Med. 2015 Jul;74(1):162-174. doi: 10.1002/mrm.25393. PubMed PMID: 25078966; PMCID: PMC4312273.
Ding Y, Tang S, Liao SG, Jia J, Oesterreich S, Lin Y, Tseng GC. Bias correction for selecting the minimal-error classifier from many machine learning models. Bioinformatics. 2014 Nov 15;30(22):3152-8. doi: 10.1093/bioinformatics/btu520. PubMed PMID: 25086004; PMCID: PMC4221122.
Boone BA, Steve J, Zenati MS, Hogg ME, Singhi AD, Bartlett DL, Zureikat AH, Bahary N, Zeh HJ 3rd. Serum CA 19-9 response to neoadjuvant therapy is associated with outcome in pancreatic adenocarcinoma. Ann Surg Oncol. 2014 Dec;21(13):4351-8. doi: 10.1245/s10434-014-3842-z. PubMed PMID: 25092157.
Hong CS, Muller L, Boyiadzis M, Whiteside TL. Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia. PLoS One. 2014;9(8):e103310. doi: 10.1371/journal.pone.0103310. PubMed PMID: 25093329; PMCID: PMC4122364.
Vera-Bolanos E, Aldape K, Yuan Y, Wu J, Wani K, Necesito-Reyes MJ, Colman H, Dhall G, Lieberman FS, Metellus P, Mikkelsen T, Omuro A, Partap S, Prados M, Robins HI, Soffietti R, Wu J, Gilbert MR, Armstrong TS, CERN Foundation.. Clinical course and progression-free survival of adult intracranial and spinal ependymoma patients. Neuro Oncol. 2015 Mar;17(3):440-7. doi: 10.1093/neuonc/nou162. PubMed PMID: 25121770; PMCID: PMC4483095.
Thunnissen E, Noguchi M, Aisner S, Beasley MB, Brambilla E, Chirieac LR, Chung JH, Dacic S, Geisinger KR, Hirsch FR, Ishikawa Y, Kerr KM, Lantejoul S, Matsuno Y, Minami Y, Moreira AL, Pelosi G, Petersen I, Roggli V, Travis WD, Wistuba I, Yatabe Y, Dziadziuszko R, Witte B, Tsao MS, Nicholson AG. Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study. J Thorac Oncol. 2014 Sep;9(9):1354-62. doi: 10.1097/JTO.0000000000000264. PubMed PMID: 25122431.
Zhang X, Liu K, Huang Y, Xu J, Li J, Ma X, Li S. Reduction-sensitive dual functional nanomicelles for improved delivery of paclitaxel. Bioconjug Chem. 2014 Sep 17;25(9):1689-96. doi: 10.1021/bc500292j. PubMed PMID: 25121577; PMCID: PMC4166038.
Brufsky AM. Current Approaches and Emerging Directions in HER2-resistant Breast Cancer. Breast Cancer (Auckl). 2014;8109-18. doi: 10.4137/BCBCR.S9453. PubMed PMID: 25125981; PMCID: PMC4125367.
Gill BS, Kim H, Houser C, Olsen A, Kelley J, Edwards RP, Comerci J, Sukumvanich P, Olawaiye AB, Huang M, Courtney-Brooks M, Beriwal S. Image-based three-dimensional conformal brachytherapy for medically inoperable endometrial carcinoma. Brachytherapy. 2014 Nov-Dec;13(6):542-7. doi: 10.1016/j.brachy.2014.07.002. PubMed PMID: 25127122.
Gilbert MR, Sturm JJ, Gooding WE, Johnson JT, Kim S. Pectoralis major myofascial onlay and myocutaneous flaps and pharyngocutaneous fistula in salvage laryngectomy. Laryngoscope. 2014 Dec;124(12):2680-6. doi: 10.1002/lary.24796. PubMed PMID: 25132580; PMCID: PMC4241124.
Gao Y, Trivedi S, Ferris RL, Koide K. Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells. Sci Rep. 2014 Aug 20;46098. doi: 10.1038/srep06098. PubMed PMID: 25139387; PMCID: PMC4138523.
Jiang Y, Djuric Z, Sen A, Ren J, Kuklev D, Waters I, Zhao L, Uhlson CL, Hong YH, Murphy RC, Normolle DP, Smith WL, Brenner DE. Biomarkers for personalizing omega-3 fatty acid dosing. Cancer Prev Res (Phila). 2014 Oct;7(10):1011-22. doi: 10.1158/1940-6207.CAPR-14-0134. PubMed PMID: 25139294; PMCID: PMC4185239.
Feng Z, Alqarni MH, Yang P, Tong Q, Chowdhury A, Wang L, Xie XQ. Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs. J Chem Inf Model. 2014 Sep 22;54(9):2483-99. doi: 10.1021/ci5002718. PubMed PMID: 25141027; PMCID: PMC4170816.
Studer A, Curran DP. The electron is a catalyst. Nat Chem. 2014 Sep;6(9):765-73. doi: 10.1038/nchem.2031. PubMed PMID: 25143210.
Gao Y, Osman S, Koide K. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014 Aug 14;5(8):863-7. doi: 10.1021/ml500025p. PubMed PMID: 25147604; PMCID: PMC4137371.
Skoda EM, Sacher JR, Kazancioglu MZ, Saha J, Wipf P. An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility. ACS Med Chem Lett. 2014 Aug 14;5(8):900-4. doi: 10.1021/ml5001504. PubMed PMID: 25147611; PMCID: PMC4137373.
Alqarni M, Myint KZ, Tong Q, Yang P, Bartlow P, Wang L, Feng R, Xie XQ. Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activities. Biochem Biophys Res Commun. 2014 Sep 26;452(3):334-9. doi: 10.1016/j.bbrc.2014.08.048. PubMed PMID: 25148941; PMCID: PMC4465889.
Vargo JA, Ferris RL, Clump DA, Heron DE. Stereotactic body radiotherapy as primary treatment for elderly patients with medically inoperable head and neck cancer. Front Oncol. 2014;4214. doi: 10.3389/fonc.2014.00214. PubMed PMID: 25157336; PMCID: PMC4128217.
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Tandon M, Salamoun JM, Carder EJ, Farber E, Xu S, Deng F, Tang H, Wipf P, Wang QJ. SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. PLoS One. 2015;10(3):e0119346. doi: 10.1371/journal.pone.0119346. PubMed PMID: 25747583; PMCID: PMC4352033.
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Lassman AB, Pugh SL, Gilbert MR, Aldape KD, Geinoz S, Beumer JH, Christner SM, Komaki R, DeAngelis LM, Gaur R, Youssef E, Wagner H, Won M, Mehta MP. Phase 2 trial of dasatinib in target-selected patients with recurrent glioblastoma (RTOG 0627). Neuro Oncol. 2015 Jul;17(7):992-8. doi: 10.1093/neuonc/nov011. PubMed PMID: 25758746; PMCID: PMC5762006.
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Lim SJ, Lim MJ, Raptis A, Hou JZ, Farah R, Marks S, Im A, Dorritie K, Sehgal A, Agha M, Lim SH. Outcome of acute myeloid leukemia patients with pulmonary nodules of uncertain etiology receiving allogeneic hematopoietic progenitor cell transplant. Eur J Haematol. 2016 Jan;96(1):55-9. doi: 10.1111/ejh.12547. PubMed PMID: 25784319.
Chattopadhyay A, Abecassis I, Redner RL. NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK. Leuk Lymphoma. 2015;56(12):3401-3406. doi: 10.3109/10428194.2015.1023799. PubMed PMID: 25791120; PMCID: PMC4743255.
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Choby GW, Kim J, Ling DC, Abberbock S, Mandal R, Kim S, Ferris RL, Duvvuri U. Transoral robotic surgery alone for oropharyngeal cancer: quality-of-life outcomes. JAMA Otolaryngol Head Neck Surg. 2015 Jun;141(6):499-504. doi: 10.1001/jamaoto.2015.0347. PubMed PMID: 25834991.
Damodaran K, Li X, Pan X, Curran DP. Dynamic Behavior of N-Heterocyclic Carbene Boranes: Boron-Carbene Bonds in B,B-Disubstituted N,N-Dimethylimidazol-2-ylidene Boranes Have Substantial Rotation Barriers. J Org Chem. 2015 May 1;80(9):4465-9. doi: 10.1021/acs.joc.5b00324. PubMed PMID: 25843519.
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Mandapathil M, Duvvuri U, Güldner C, Teymoortash A, Lawson G, Werner JA. Transoral surgery for oropharyngeal tumors using the Medrobotics(®) Flex(®) System - a case report. Int J Surg Case Rep. 2015;10173-5. doi: 10.1016/j.ijscr.2015.03.030. PubMed PMID: 25853845; PMCID: PMC4430123.
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Hua Y, Strock CJ, Johnston PA. High content screening biosensor assay to identify disruptors of p53-hDM2 protein-protein interactions. Methods Mol Biol. 2015;1278555-65. doi: 10.1007/978-1-4939-2425-7_37. PubMed PMID: 25859976.
Shakir M, Tang D, Zeh HJ, Tang SW, Anderson CJ, Bahary N, Lotze MT. The chemokine receptors CXCR4/CXCR7 and their primary heterodimeric ligands CXCL12 and CXCL12/high mobility group box 1 in pancreatic cancer growth and development: finding flow. Pancreas. 2015 May;44(4):528-34. doi: 10.1097/MPA.0000000000000298. PubMed PMID: 25872129.
Dudley B, Brand RE, Thull D, Bahary N, Nikiforova MN, Pai RK. Germline MLH1 Mutations Are Frequently Identified in Lynch Syndrome Patients With Colorectal and Endometrial Carcinoma Demonstrating Isolated Loss of PMS2 Immunohistochemical Expression. Am J Surg Pathol. 2015 Aug;39(8):1114-20. doi: 10.1097/PAS.0000000000000425. PubMed PMID: 25871621.
Espeland MA, Newman AB, Sink K, Gill TM, King AC, Miller ME, Guralnik J, Katula J, Church T, Manini T, Reid KF, McDermott MM, LIFE Study Group.. Associations Between Ankle-Brachial Index and Cognitive Function: Results From the Lifestyle Interventions and Independence for Elders Trial. J Am Med Dir Assoc. 2015 Aug 1;16(8):682-9. doi: 10.1016/j.jamda.2015.03.010. PubMed PMID: 25869993; PMCID: PMC4516564.
Li M, Yang Z, Vollmer LL, Gao Y, Fu Y, Liu C, Chen X, Liu P, Vogt A, Yin XM. AMDE-1 is a dual function chemical for autophagy activation and inhibition. PLoS One. 2015;10(3):e0122083. doi: 10.1371/journal.pone.0122083. PubMed PMID: 25894744; PMCID: PMC4403922.
Holt DE, Gill BS, Clump DA, Leeman JE, Burton SA, Amankulor NM, Engh JA, Heron DE. Tumor bed radiosurgery following resection and prior stereotactic radiosurgery for locally persistent brain metastasis. Front Oncol. 2015;584. doi: 10.3389/fonc.2015.00084. PubMed PMID: 25905042; PMCID: PMC4389371.
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Hemphill J, Borchardt EK, Brown K, Asokan A, Deiters A. Optical Control of CRISPR/Cas9 Gene Editing. J Am Chem Soc. 2015 May 6;137(17):5642-5. doi: 10.1021/ja512664v. PubMed PMID: 25905628; PMCID: PMC4919123.
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Leung AS, Rath TJ, Hughes MA, Kim S, Branstetter BF 4th. Optimal timing of first posttreatment FDG PET/CT in head and neck squamous cell carcinoma. Head Neck. 2016 Apr;38 Suppl 1E853-8. doi: 10.1002/hed.24112. PubMed PMID: 25917499.
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Mandal R, Duvvuri U, Ferris RL, Kaffenberger TM, Choby GW, Kim S. Analysis of post-transoral robotic-assisted surgery hemorrhage: Frequency, outcomes, and prevention. Head Neck. 2016 Apr;38 Suppl 1E776-82. doi: 10.1002/hed.24101. PubMed PMID: 25916790.
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Javadov S, Jang S, Rodriguez-Reyes N, Rodriguez-Zayas AE, Soto Hernandez J, Krainz T, Wipf P, Frontera W. Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats. Oncotarget. 2015 Nov 24;6(37):39469-81. doi: 10.18632/oncotarget.5783. PubMed PMID: 26415224; PMCID: PMC4741839.
Chao DT, Shah NH, Zeh HJ 3rd, Bahary N, Whitcomb DC, Brand RE. Increased Serum Insulin Exposure Does Not Affect Age or Stage of Pancreatic Adenocarcinoma Diagnosis in Patients With Diabetes Mellitus. Pancreas. 2016 Feb;45(2):228-33. doi: 10.1097/MPA.0000000000000439. PubMed PMID: 26418902; PMCID: PMC4710546.
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Deeken JF, Beumer JH, Anders NM, Wanjiku T, Rusnak M, Rudek MA. Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib. Cancer Chemother Pharmacol. 2015 Oct;76(4):813-9. doi: 10.1007/s00280-015-2856-y. PubMed PMID: 26330331; PMCID: PMC4577782.
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Prichard JW, Davison JM, Campbell BB, Repa KA, Reese LM, Nguyen XM, Li J, Foxwell T, Taylor DL, Critchley-Thorne RJ. TissueCypher(™): A systems biology approach to anatomic pathology. J Pathol Inform. 2015;648. doi: 10.4103/2153-3539.163987. PubMed PMID: 26430536; PMCID: PMC4584447.
Gebhardt BJ, Rajagopalan MS, Gill BS, Heron DE, Rakfal SM, Flickinger JC, Beriwal S. Impact of dynamic changes to a bone metastases pathway in a large, integrated, National Cancer Institute-designated comprehensive cancer center network. Pract Radiat Oncol. 2015 Nov-Dec;5(6):398-405. doi: 10.1016/j.prro.2015.06.013. PubMed PMID: 26432676.
Beumer JH, Fu KY, Anyang BN, Siegfried JM, Bakkenist CJ. Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma. BMC Cancer. 2015 Oct 5;15649. doi: 10.1186/s12885-015-1649-3. PubMed PMID: 26438152; PMCID: PMC4595318.
Kim J, Kim S, Albergotti WG, Choi PA, Kaplan DJ, Abberbock S, Johnson JT, Gildener-Leapman N. Selection of Ideal Candidates for Surgical Salvage of Head and Neck Squamous Cell Carcinoma: Effect of the Charlson-Age Comorbidity Index and Oncologic Characteristics on 1-Year Survival and Hospital Course. JAMA Otolaryngol Head Neck Surg. 2015 Dec;141(12):1059-65. doi: 10.1001/jamaoto.2015.2158. PubMed PMID: 26447790; PMCID: PMC4884653.
Yu L, Wang Z, Huang M, Li Y, Zeng K, Lei J, Hu H, Chen B, Lu J, Xie W, Zeng S. Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor. Biochim Biophys Acta. 2016 Sep;1859(9):1100-1111. doi: 10.1016/j.bbagrm.2015.10.001. PubMed PMID: 26455953.
Studer A, Curran DP. Catalysis of Radical Reactions: A Radical Chemistry Perspective. Angew Chem Int Ed Engl. 2016 Jan 4;55(1):58-102. doi: 10.1002/anie.201505090. PubMed PMID: 26459814.
Gough A, Shun TY, Lansing Taylor D, Schurdak M. A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens. Methods. 2016 Mar 1;9612-26. doi: 10.1016/j.ymeth.2015.10.007. PubMed PMID: 26476369; PMCID: PMC5200891.
Merriman JD, Sereika SM, Brufsky AM, McAuliffe PF, McGuire KP, Myers JS, Phillips ML, Ryan CM, Gentry AL, Jones LD, Bender CM. Trajectories of self-reported cognitive function in postmenopausal women during adjuvant systemic therapy for breast cancer. Psychooncology. 2017 Jan;26(1):44-52. doi: 10.1002/pon.4009. PubMed PMID: 26486371; PMCID: PMC4969219.
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Singhi AD, Krasinskas AM, Choudry HA, Bartlett DL, Pingpank JF, Zeh HJ, Luvison A, Fuhrer K, Bahary N, Seethala RR, Dacic S. The prognostic significance of BAP1, NF2, and CDKN2A in malignant peritoneal mesothelioma. Mod Pathol. 2016 Jan;29(1):14-24. doi: 10.1038/modpathol.2015.121. PubMed PMID: 26493618.
Wang P, Bahreini A, Gyanchandani R, Lucas PC, Hartmaier RJ, Watters RJ, Jonnalagadda AR, Trejo Bittar HE, Berg A, Hamilton RL, Kurland BF, Weiss KR, Mathew A, Leone JP, Davidson NE, Nikiforova MN, Brufsky AM, Ambros TF, Stern AM, Puhalla SL, Lee AV, Oesterreich S. Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients. Clin Cancer Res. 2016 Mar 1;22(5):1130-7. doi: 10.1158/1078-0432.CCR-15-1534. PubMed PMID: 26500237; PMCID: PMC4775406.
Quan K, Xu KM, Lalonde R, Horne ZD, Bernard ME, McCoy C, Clump DA, Burton SA, Heron DE. Treatment Plan Technique and Quality for Single-Isocenter Stereotactic Ablative Radiotherapy of Multiple Lung Lesions with Volumetric-Modulated Arc Therapy or Intensity-Modulated Radiosurgery. Front Oncol. 2015;5213. doi: 10.3389/fonc.2015.00213. PubMed PMID: 26500888; PMCID: PMC4594030.
Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. Oncotarget. 2015 Dec 1;6(38):40866-79. doi: 10.18632/oncotarget.5885. PubMed PMID: 26506423; PMCID: PMC4747374.
Schenker Y, Arnold RM, Bauman JE, Heron DE, Johnson JT. An enhanced role for palliative care in the multidisciplinary approach to high-risk head and neck cancer. Cancer. 2016 Feb 1;122(3):340-3. doi: 10.1002/cncr.29754. PubMed PMID: 26505177.
Bakkenist CJ, Beumer JH, Schmitz JC. ATM serine-1981 phosphorylation is a plausible biomarker. Cell Cycle. 2015;14(20):3207-8. doi: 10.1080/15384101.2015.1084205. PubMed PMID: 26517194; PMCID: PMC4825586.
Thottam PJ, Govil N, Duvvuri U, Mehta D. Transoral robotic surgery for sleep apnea in children: Is it effective? Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2234-7. doi: 10.1016/j.ijporl.2015.10.010. PubMed PMID: 26518466.
Beumer JH, Pillai VC, Parise RA, Christner SM, Kiesel BF, Rudek MA, Venkataramanan R. Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation. Br J Clin Pharmacol. 2015 Nov;80(5):1097-108. doi: 10.1111/bcp.12723. PubMed PMID: 26178713; PMCID: PMC4631182.
Catenacci DV, Junttila MR, Karrison T, Bahary N, Horiba MN, Nattam SR, Marsh R, Wallace J, Kozloff M, Rajdev L, Cohen D, Wade J, Sleckman B, Lenz HJ, Stiff P, Kumar P, Xu P, Henderson L, Takebe N, Salgia R, Wang X, Stadler WM, de Sauvage FJ, Kindler HL. Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer. J Clin Oncol. 2015 Dec 20;33(36):4284-92. doi: 10.1200/JCO.2015.62.8719. PubMed PMID: 26527777; PMCID: PMC4678179.
Chapman BV, Rajagopalan MS, Heron DE, Flickinger JC, Beriwal S. Clinical Pathways: A Catalyst for the Adoption of Hypofractionation for Early-Stage Breast Cancer. Int J Radiat Oncol Biol Phys. 2015 Nov 15;93(4):854-61. doi: 10.1016/j.ijrobp.2015.08.013. PubMed PMID: 26530754.
Wilson BA, Alam MS, Guszczynski T, Jakob M, Shenoy SR, Mitchell CA, Goncharova EI, Evans JR, Wipf P, Liu G, Ashwell JD, O'Keefe BR. Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor. J Biomol Screen. 2016 Mar;21(3):277-89. doi: 10.1177/1087057115615518. PubMed PMID: 26538432.
Cecchini RS, Swain SM, Costantino JP, Rastogi P, Jeong JH, Anderson SJ, Tang G, Geyer CE Jr, Lembersky BC, Romond EH, Paterson AH, Wolmark N. Body Mass Index at Diagnosis and Breast Cancer Survival Prognosis in Clinical Trial Populations from NRG Oncology/NSABP B-30, B-31, B-34, and B-38. Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):51-9. doi: 10.1158/1055-9965.EPI-15-0334-T. PubMed PMID: 26545405; PMCID: PMC4713289.
Amjad AI, Parikh RA, Appleman LJ, Hahm ER, Singh K, Singh SV. Broccoli-Derived Sulforaphane and Chemoprevention of Prostate Cancer: From Bench to Bedside. Curr Pharmacol Rep. 2015 Nov 1;1(6):382-390. doi: 10.1007/s40495-015-0034-x. PubMed PMID: 26557472; PMCID: PMC4635516.
Dixit R, Kemp C, Kulich S, Seethala R, Chiosea S, Ling S, Ha PK, Duvvuri U. TMEM16A/ANO1 is differentially expressed in HPV-negative versus HPV-positive head and neck squamous cell carcinoma through promoter methylation. Sci Rep. 2015 Nov 13;516657. doi: 10.1038/srep16657. PubMed PMID: 26563938; PMCID: PMC4643216.
Yu FT, Chen X, Wang J, Qin B, Villanueva FS. Low Intensity Ultrasound Mediated Liposomal Doxorubicin Delivery Using Polymer Microbubbles. Mol Pharm. 2016 Jan 4;13(1):55-64. doi: 10.1021/acs.molpharmaceut.5b00421. PubMed PMID: 26567985; PMCID: PMC5378154.
Wang Q, Gold N, Frasch MG, Huang H, Thiriet M, Wang X. Mathematical Model of Cardiovascular and Metabolic Responses to Umbilical Cord Occlusions in Fetal Sheep. Bull Math Biol. 2015 Dec;77(12):2264-93. doi: 10.1007/s11538-015-0122-4. PubMed PMID: 26582358; PMCID: PMC5359013.
Jane EP, Premkumar DR, Cavaleri JM, Sutera PA, Rajasekar T, Pollack IF. Dinaciclib, a Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation of Mcl-1 and Enhances ABT-737-Mediated Cell Death in Malignant Human Glioma Cell Lines. J Pharmacol Exp Ther. 2016 Feb;356(2):354-65. doi: 10.1124/jpet.115.230052. PubMed PMID: 26585571; PMCID: PMC6047232.
Chen X, Wang J, Pacella JJ, Villanueva FS. Dynamic Behavior of Microbubbles during Long Ultrasound Tone-Burst Excitation: Mechanistic Insights into Ultrasound-Microbubble Mediated Therapeutics Using High-Speed Imaging and Cavitation Detection. Ultrasound Med Biol. 2016 Feb;42(2):528-538. doi: 10.1016/j.ultrasmedbio.2015.09.017. PubMed PMID: 26603628; PMCID: PMC4698009.
Shehu AI, Li G, Xie W, Ma X. The pregnane X receptor in tuberculosis therapeutics. Expert Opin Drug Metab Toxicol. 2016;12(1):21-30. doi: 10.1517/17425255.2016.1121381. PubMed PMID: 26592418; PMCID: PMC4708888.
Land SR, Walcott FL, Liu Q, Wickerham DL, Costantino JP, Ganz PA. Symptoms and QOL as Predictors of Chemoprevention Adherence in NRG Oncology/NSABP Trial P-1. J Natl Cancer Inst. 2016 Apr;108(4): doi: 10.1093/jnci/djv365. PubMed PMID: 26615179; PMCID: PMC4675829.
Sanei-Moghaddam A, Ma T, Goughnour SL, Edwards RP, Lounder PJ, Ismail N, Comerci JT, Mansuria SM, Linkov F. Changes in Hysterectomy Trends After the Implementation of a Clinical Pathway. Obstet Gynecol. 2016 Jan;127(1):139-47. doi: 10.1097/AOG.0000000000001185. PubMed PMID: 26646126.
Zhang H, Hay EB, Geib SJ, Curran DP. Fates of imine intermediates in radical cyclizations of N-sulfonylindoles and ene-sulfonamides. Beilstein J Org Chem. 2015;111649-55. doi: 10.3762/bjoc.11.181. PubMed PMID: 26664585; PMCID: PMC4660904.
Agha A, Sehgal A, Lim MJ, Weber D, Hou JZ, Farah R, Raptis A, Im A, Dorritie K, Marks S, Agha M, Lim SH. Peri-transplant clostridium difficile infections in patients undergoing allogeneic hematopoietic progenitor cell transplant. Am J Hematol. 2016 Mar;91(3):291-4. doi: 10.1002/ajh.24263. PubMed PMID: 26661725.
Skrypnyk NI, Sanker S, Skvarca LB, Novitskaya T, Woods C, Chiba T, Patel K, Goldberg ND, McDermott L, Vinson PN, Calcutt MW, Huryn DM, Vernetti LA, Vogt A, Hukriede NA, de Caestecker MP. Delayed treatment with PTBA analogs reduces postinjury renal fibrosis after kidney injury. Am J Physiol Renal Physiol. 2016 Apr 15;310(8):F705-F716. doi: 10.1152/ajprenal.00503.2015. PubMed PMID: 26661656; PMCID: PMC4835925.
Hodnett BL, Schmitt NC, Thirumala PD, Duvvuri U. Intraoperative identification of the human communicating nerve during thyroidectomy. J Surg Case Rep. 2015 Dec 13;2015(12): doi: 10.1093/jscr/rjv154. PubMed PMID: 26666834; PMCID: PMC4677275.
Stupp R, Taillibert S, Kanner AA, Kesari S, Steinberg DM, Toms SA, Taylor LP, Lieberman F, Silvani A, Fink KL, Barnett GH, Zhu JJ, Henson JW, Engelhard HH, Chen TC, Tran DD, Sroubek J, Tran ND, Hottinger AF, Landolfi J, Desai R, Caroli M, Kew Y, Honnorat J, Idbaih A, Kirson ED, Weinberg U, Palti Y, Hegi ME, Ram Z. Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial. JAMA. 2015 Dec 15;314(23):2535-43. doi: 10.1001/jama.2015.16669. PubMed PMID: 26670971.
Davar D, Socinski MA, Dacic S, Burns TF. Near complete response after single dose of nivolumab in patient with advanced heavily pre-treated KRAS mutant pulmonary adenocarcinoma. Exp Hematol Oncol. 2015;434. doi: 10.1186/s40164-015-0029-7. PubMed PMID: 26673119; PMCID: PMC4678465.
Yardley DA, Brufsky A, Coleman RE, Conte PF, Cortes J, Glück S, Nabholtz JM, O'Shaughnessy J, Beck RM, Ko A, Renschler MF, Barton D, Harbeck N. Phase II/III weekly nab-paclitaxel plus gemcitabine or carboplatin versus gemcitabine/carboplatin as first-line treatment of patients with metastatic triple-negative breast cancer (the tnAcity study): study protocol for a randomized controlled trial. Trials. 2015 Dec 16;16575. doi: 10.1186/s13063-015-1101-7. PubMed PMID: 26673577; PMCID: PMC4682258.
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Greenberger J, Kagan V, Bayir H, Wipf P, Epperly M. Antioxidant Approaches to Management of Ionizing Irradiation Injury. Antioxidants (Basel). 2015 Jan 23;4(1):82-101. doi: 10.3390/antiox4010082. PubMed PMID: 26785339; PMCID: PMC4665573.
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Bodea CA, Neale BM, Ripke S, International IBD Genetics Consortium., Daly MJ, Devlin B, Roeder K. A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. Am J Hum Genet. 2016 May 5;98(5):857-868. doi: 10.1016/j.ajhg.2016.02.025. PubMed PMID: 27087321; PMCID: PMC4864319.
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Shindo M, Lee JA, Lubitz CC, McCoy KL, Orloff LA, Tufano RP, Pasieka JL. The Changing Landscape of Primary, Secondary, and Tertiary Hyperparathyroidism: Highlights from the American College of Surgeons Panel, "What's New for the Surgeon Caring for Patients with Hyperparathyroidism". J Am Coll Surg. 2016 Jun;222(6):1240-50. doi: 10.1016/j.jamcollsurg.2016.02.024. PubMed PMID: 27107975.
Horne ZD, Glaser SM, Vargo JA, Ferris RL, Balasubramani GK, Clump DA, Heron DE, Beriwal S. Confirmation of proposed human papillomavirus risk-adapted staging according to AJCC/UICC TNM criteria for positive oropharyngeal carcinomas. Cancer. 2016 Jul 1;122(13):2021-30. doi: 10.1002/cncr.30021. PubMed PMID: 27111669.
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Wang WW, Zeng Y, Wu B, Deiters A, Liu WR. A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes. ACS Chem Biol. 2016 Jul 15;11(7):1973-81. doi: 10.1021/acschembio.6b00243. PubMed PMID: 27152839; PMCID: PMC5478164.
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Curran DP, McFadden TR. Understanding Initiation with Triethylboron and Oxygen: The Differences between Low-Oxygen and High-Oxygen Regimes. J Am Chem Soc. 2016 Jun 22;138(24):7741-52. doi: 10.1021/jacs.6b04014. PubMed PMID: 27243276.
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Villaruz LC, Jones H, Dacic S, Abberbock S, Kurland BF, Stabile LP, Siegfried JM, Conrads TP, Smith NR, O'Connor MJ, Pierce AJ, Bakkenist CJ. ATM protein is deficient in over 40% of lung adenocarcinomas. Oncotarget. 2016 Sep 6;7(36):57714-57725. doi: 10.18632/oncotarget.9757. PubMed PMID: 27259260; PMCID: PMC5295384.
Clark AJ, Curran DP, Fox DJ, Ghelfi F, Guy CS, Hay B, James N, Phillips JM, Roncaglia F, Sellars PB, Wilson P, Zhang H. Axially Chiral Enamides: Substituent Effects, Rotation Barriers, and Implications for their Cyclization Reactions. J Org Chem. 2016 Jul 1;81(13):5547-65. doi: 10.1021/acs.joc.6b00889. PubMed PMID: 27267662.
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Newsome H, Mandapathil M, Koh YW, Duvvuri U. Utility of the Highly Articulated Flex Robotic System for Head and Neck Procedures: A Cadaveric Study. Ann Otol Rhinol Laryngol. 2016 Sep;125(9):758-63. doi: 10.1177/0003489416653409. PubMed PMID: 27287677.
Hoefflin R, Lahrmann B, Warsow G, Hübschmann D, Spath C, Walter B, Chen X, Hofer L, Macher-Goeppinger S, Tolstov Y, Korzeniewski N, Duensing A, Grüllich C, Jäger D, Perner S, Schönberg G, Nyarangi-Dix J, Isaac S, Hatiboglu G, Teber D, Hadaschik B, Pahernik S, Roth W, Eils R, Schlesner M, Sültmann H, Hohenfellner M, Grabe N, Duensing S. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nat Commun. 2016 Jun 13;7ncomms11845. doi: 10.1038/ncomms11845. PubMed PMID: 27291893; PMCID: PMC4910022.
Salamoun JM, McQueeney KE, Patil K, Geib SJ, Sharlow ER, Lazo JS, Wipf P. Photooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor. Org Biomol Chem. 2016 Jul 6;14(27):6398-402. doi: 10.1039/c6ob00946h. PubMed PMID: 27291491; PMCID: PMC4935606.
Im A, Amjad A, Agha M, Raptis A, Hou JZ, Farah R, Lim S, Sehgal A, Dorritie KA, Redner RL, McLaughlin B, Shuai Y, Duggal S, Boyiadzis M. Mitoxantrone and Etoposide for the Treatment of Acute Myeloid Leukemia Patients in First Relapse. Oncol Res. 2016;24(2):73-80. doi: 10.3727/096504016X14586627440156. PubMed PMID: 27296947.
Ling DC, Vargo JA, Ferris RL, Ohr J, Clump DA, Yau WW, Duvvuri U, Kim S, Johnson JT, Bauman JE, Branstetter BF, Heron DE. Risk of Severe Toxicity According to Site of Recurrence in Patients Treated With Stereotactic Body Radiation Therapy for Recurrent Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):973-980. doi: 10.1016/j.ijrobp.2016.02.049. PubMed PMID: 27302512.
Hu J, Hu Z, Zhang Y, Gou X, Mu Y, Wang L, Xie XQ. Metal binding mediated conformational change of XPA protein:a potential cytotoxic mechanism of nickel in the nucleotide excision repair. J Mol Model. 2016 Jul;22(7):156. doi: 10.1007/s00894-016-3017-x. PubMed PMID: 27307058; PMCID: PMC5327499.
Wang C, Kundaria S, Fernandez-Miranda J, Duvvuri U. A description of the anatomy of the glossopharyngeal nerve as encountered in transoral surgery. Laryngoscope. 2016 Sep;126(9):2010-5. doi: 10.1002/lary.25706. PubMed PMID: 27312369.
Smith DC, Powderly J, Lee JJ, Shepard DR, Wallin J, Chaudhary A, Chao GY, Ng WT, Mitchell MI, Grau G, Kurek R, LoRusso P. Evaluation of the effect of necitumumab on the corrected QT interval in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2016 Aug;78(2):271-80. doi: 10.1007/s00280-016-3074-y. PubMed PMID: 27312733.
Retseck J, VanderWeele R, Lin HM, Lin Y, Butterfield LH, Tarhini AA. Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab. J Immunother Cancer. 2016;438. doi: 10.1186/s40425-016-0141-1. PubMed PMID: 27330811; PMCID: PMC4915044.
Bauman JE, Zang Y, Sen M, Li C, Wang L, Egner PA, Fahey JW, Normolle DP, Grandis JR, Kensler TW, Johnson DE. Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane. Cancer Prev Res (Phila). 2016 Jul;9(7):547-57. doi: 10.1158/1940-6207.CAPR-15-0290. PubMed PMID: 27339168; PMCID: PMC4930727.
Erdem C, Nagle AM, Casa AJ, Litzenburger BC, Wang YF, Taylor DL, Lee AV, Lezon TR. Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways. Mol Cell Proteomics. 2016 Sep;15(9):3045-57. doi: 10.1074/mcp.M115.057729. PubMed PMID: 27364358; PMCID: PMC5013316.
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Li J, Li S. Reply to: "miR-122 expression is not regulated during activation of hepatic stellate cells". J Hepatol. 2016 Oct;65(4):868. doi: 10.1016/j.jhep.2016.06.020. PubMed PMID: 27388922.
Clark AM, Ma B, Taylor DL, Griffith L, Wells A. Liver metastases: Microenvironments and ex-vivo models. Exp Biol Med (Maywood). 2016 Sep;241(15):1639-52. doi: 10.1177/1535370216658144. PubMed PMID: 27390264; PMCID: PMC4999624.
Singhi AD, Liu TC, Roncaioli JL, Cao D, Zeh HJ, Zureikat AH, Tsung A, Marsh JW, Lee KK, Hogg ME, Bahary N, Brand RE, McGrath KM, Slivka A, Cressman KL, Fuhrer K, O'Sullivan RJ. Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors. Clin Cancer Res. 2017 Jan 15;23(2):600-609. doi: 10.1158/1078-0432.CCR-16-1113. PubMed PMID: 27407094; PMCID: PMC6560642.
Sun J, Chen Y, Li K, Huang Y, Fu X, Zhang X, Zhao W, Wei Y, Xu L, Zhang P, Venkataramanan R, Li S. A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel. Acta Biomater. 2016 Oct 1;43282-291. doi: 10.1016/j.actbio.2016.07.014. PubMed PMID: 27422196; PMCID: PMC5012958.
Dhir M, Jones HL, Shuai Y, Clifford AK, Perkins S, Steve J, Hogg ME, Choudry MH, Pingpank JF, Holtzman MP, Zeh HJ 3rd, Bahary N, Bartlett DL, Zureikat AH. Hepatic Arterial Infusion in Combination with Modern Systemic Chemotherapy is Associated with Improved Survival Compared with Modern Systemic Chemotherapy Alone in Patients with Isolated Unresectable Colorectal Liver Metastases: A Case-Control Study. Ann Surg Oncol. 2017 Jan;24(1):150-158. doi: 10.1245/s10434-016-5418-6. PubMed PMID: 27431415.
Hartsock B, Lim MJ, Roth CG, Raptis N, Weber D, Sehgal A, Boyiadzis M, Raptis A, Hou JZ, Im A, Dorritie K, Marks S, Agha M, Lim SH. ICU intervention during induction chemotherapy for adult patients with newly diagnosed acute myeloid leukemia. Leuk Res. 2016 Sep;4816-9. doi: 10.1016/j.leukres.2016.07.001. PubMed PMID: 27442892.
Ling DC, Vargo JA, Heron DE. Stereotactic Body Radiation Therapy for Recurrent Head and Neck Cancer. Cancer J. 2016 Jul-Aug;22(4):302-6. doi: 10.1097/PPO.0000000000000208. PubMed PMID: 27441751.
Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. doi: 10.1073/pnas.1603883113. PubMed PMID: 27450084; PMCID: PMC4987817.
Holleran JL, Eiseman JL, Parise RA, Kummar S, Beumer JH. LC-MS/MS assay for the quantitation of FdCyd and its metabolites FdUrd and FU in human plasma. J Pharm Biomed Anal. 2016 Sep 10;129359-366. doi: 10.1016/j.jpba.2016.07.027. PubMed PMID: 27454087; PMCID: PMC5003709.
Steiman J, Soran A, McAuliffe P, Diego E, Bonaventura M, Johnson R, Ahrendt G, McGuire K. Predictive value of axillary nodal imaging by magnetic resonance imaging based on breast cancer subtype after neoadjuvant chemotherapy. J Surg Res. 2016 Jul;204(1):237-41. doi: 10.1016/j.jss.2016.04.048. PubMed PMID: 27451892.
Govil N, Schmitt NC, Kim S. Cervical Osteomyelitis After Pharyngeal Surgical Manipulation. JAMA Otolaryngol Head Neck Surg. 2016 Nov 1;142(11):1130. doi: 10.1001/jamaoto.2016.1837. PubMed PMID: 27467191; PMCID: PMC5444660.
Kopechek JA, Carson AR, McTiernan CF, Chen X, Klein EC, Villanueva FS. Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound. PLoS One. 2016;11(7):e0159751. doi: 10.1371/journal.pone.0159751. PubMed PMID: 27471848; PMCID: PMC4966949.
Parikh RA, Appleman LJ, Beumer JH, Matczak E, Chu E. Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features. Clin Genitourin Cancer. 2017 Feb;15(1):7-22. doi: 10.1016/j.clgc.2016.05.011. PubMed PMID: 27473523.
Gojo I, Beumer JH, Pratz KW, McDevitt MA, Baer MR, Blackford AL, Smith BD, Gore SD, Carraway HE, Showel MM, Levis MJ, Dezern AE, Gladstone DE, Ji JJ, Wang L, Kinders RJ, Pouquet M, Ali-Walbi I, Rudek MA, Poh W, Herman JG, Karnitz LM, Kaufmann SH, Chen A, Karp JE. A Phase 1 Study of the PARP Inhibitor Veliparib in Combination with Temozolomide in Acute Myeloid Leukemia. Clin Cancer Res. 2017 Feb 1;23(3):697-706. doi: 10.1158/1078-0432.CCR-16-0984. PubMed PMID: 27503200; PMCID: PMC5290001.
Brufsky A. Is there room for bevacizumab in metastatic breast cancer? Lancet Oncol. 2016 Sep;17(9):1175-6. doi: 10.1016/S1470-2045(16)30295-9. PubMed PMID: 27501769.
Wang D, Braiteh F, Lee JJ, Denlinger CS, Shepard DR, Chaudhary A, Lin Y, Gao L, Asakiewicz C, Nasroulah F, LoRusso P. Lack of pharmacokinetic drug-drug interaction between ramucirumab and irinotecan in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2016 Oct;78(4):727-33. doi: 10.1007/s00280-016-3125-4. PubMed PMID: 27507037.
Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, Fu Y, Lin Y, Wen W, Li S, Liu X, Huang H, Vogt A, Liu P, Yin XM, Li M. Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy. Cell Death Dis. 2016 Aug 11;7(8):e2330. doi: 10.1038/cddis.2016.236. PubMed PMID: 27512951; PMCID: PMC5108321.
Brufsky AM, Davidson NE. Multiparametric Genomic Assays for Breast Cancer: Time for the Next Generation? Clin Cancer Res. 2016 Oct 15;22(20):4963-4965. doi: 10.1158/1078-0432.CCR-16-1513. PubMed PMID: 27521446; PMCID: PMC5154749.
Zhao Z, Xu D, Li S, He B, Huang Y, Xu M, Ren S, Li S, Wang H, Xie W. Activation of Liver X Receptor Attenuates Oleic Acid-Induced Acute Respiratory Distress Syndrome. Am J Pathol. 2016 Oct;186(10):2614-22. doi: 10.1016/j.ajpath.2016.06.018. PubMed PMID: 27520356; PMCID: PMC5222979.
Milligan JA, Busacca CA, Senanayake CH, Wipf P. Hydrophosphination of Bicyclo[1.1.0]butane-1-carbonitriles. Org Lett. 2016 Sep 2;18(17):4300-3. doi: 10.1021/acs.orglett.6b02051. PubMed PMID: 27518583.
He S, Gill BS, Heron DE, Kelley JL, Sukumvanich P, Olawaiye AB, Edwards RP, Comerci J, Beriwal S. Long-term outcomes using adjuvant pelvic intensity modulated radiation therapy (IMRT) for endometrial carcinoma. Pract Radiat Oncol. 2017 Jan - Feb;7(1):19-25. doi: 10.1016/j.prro.2016.06.005. PubMed PMID: 27527897.
Garbacz WG, Lu P, Miller TM, Poloyac SM, Eyre NS, Mayrhofer G, Xu M, Ren S, Xie W. Hepatic Overexpression of CD36 Improves Glycogen Homeostasis and Attenuates High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance. Mol Cell Biol. 2016 Nov 1;36(21):2715-2727. doi: 10.1128/MCB.00138-16. PubMed PMID: 27528620; PMCID: PMC5064218.
Albergotti WG, Davis KS, Abberbock S, Bauman JE, Ohr J, Clump DA, Heron DE, Duvvuri U, Kim S, Johnson JT, Ferris RL. Association of pretreatment body mass index and survival in human papillomavirus positive oropharyngeal squamous cell carcinoma. Oral Oncol. 2016 Sep;6055-60. doi: 10.1016/j.oraloncology.2016.07.003. PubMed PMID: 27531873; PMCID: PMC4991628.
Zhao M, Huang Y, Chen Y, Xu J, Li S, Guo X. PEG-Fmoc-Ibuprofen Conjugate as a Dual Functional Nanomicellar Carrier for Paclitaxel. Bioconjug Chem. 2016 Sep 21;27(9):2198-205. doi: 10.1021/acs.bioconjchem.6b00415. PubMed PMID: 27532881.
Gyanchandani R, Kota KJ, Jonnalagadda AR, Minteer T, Knapick BA, Oesterreich S, Brufsky AM, Lee AV, Puhalla SL. Detection of ESR1 mutations in circulating cell-free DNA from patients with metastatic breast cancer treated with palbociclib and letrozole. Oncotarget. 2017 Sep 15;8(40):66901-66911. doi: 10.18632/oncotarget.11383. PubMed PMID: 28978004; PMCID: PMC5620144.
de Velasco G, Miao D, Voss MH, Hakimi AA, Hsieh JJ, Tannir NM, Tamboli P, Appleman LJ, Rathmell WK, Van Allen EM, Choueiri TK. Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups. Cancer Immunol Res. 2016 Oct;4(10):820-822. doi: 10.1158/2326-6066.CIR-16-0110. PubMed PMID: 27538576; PMCID: PMC5050137.
Salamoun JM, Wipf P. Allosteric Modulation of Phosphatase Activity May Redefine Therapeutic Value. J Med Chem. 2016 Sep 8;59(17):7771-2. doi: 10.1021/acs.jmedchem.6b01210. PubMed PMID: 27539118.
Sgroi DC, Brufsky A. Biomarkers for Early-Stage Breast Cancer: Clinical Utility for Extended Adjuvant Treatment Decisions. J Clin Oncol. 2016 Nov 10;34(32):3941-3942. doi: 10.1200/JCO.2016.67.2949. PubMed PMID: 27551134.
Helfield B, Chen X, Watkins SC, Villanueva FS. Biophysical insight into mechanisms of sonoporation. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9983-8. doi: 10.1073/pnas.1606915113. PubMed PMID: 27551081; PMCID: PMC5018802.
Johnson JK, Skoda EM, Zhou J, Parrinello E, Wang D, O'Malley K, Eyer BR, Kazancioglu M, Eisermann K, Johnston PA, Nelson JB, Wang Z, Wipf P. Small Molecule Antagonists of the Nuclear Androgen Receptor for the Treatment of Castration-Resistant Prostate Cancer. ACS Med Chem Lett. 2016 Aug 11;7(8):785-90. doi: 10.1021/acsmedchemlett.6b00186. PubMed PMID: 27563404; PMCID: PMC4983742.
Layne AS, Hsu FC, Blair SN, Chen SH, Dungan J, Fielding RA, Glynn NW, Hajduk AM, King AC, Manini TM, Marsh AP, Pahor M, Pellegrini CA, Buford TW, LIFE Study Investigators.. Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study. Arch Phys Med Rehabil. 2017 Jan;98(1):11-24.e3. doi: 10.1016/j.apmr.2016.07.019. PubMed PMID: 27568165; PMCID: PMC5183463.
Yardley DA, Reeves J, Dees EC, Osborne C, Paul D, Ademuyiwa F, Soliman H, Guthrie T, Andersen J, Krekow L, Choksi J, Daniel B, Danso M, Favret A, Oommen S, Brufsky A, Bromund JL, Lin Y, Ibrahim AB, Richards PD. Ramucirumab With Eribulin Versus Eribulin in Locally Recurrent or Metastatic Breast Cancer Previously Treated With Anthracycline and Taxane Therapy: A Multicenter, Randomized, Phase II Study. Clin Breast Cancer. 2016 Dec;16(6):471-479.e1. doi: 10.1016/j.clbc.2016.07.005. PubMed PMID: 27569274.
Mor A, White A, Zhang K, Thompson M, Esparza M, Muñoz-Moreno R, Koide K, Lynch KW, García-Sastre A, Fontoura BM. Influenza virus mRNA trafficking through host nuclear speckles. Nat Microbiol. 2016 May 27;1(7):16069. doi: 10.1038/nmicrobiol.2016.69. PubMed PMID: 27572970; PMCID: PMC4917225.
Somasundaram A, Socinski MA, Villaruz LC. Immune checkpoint blockade in lung cancer. Discov Med. 2016 Aug;22(119):55-65. PubMed PMID: 27585231.
Fancher AT, Hua Y, Camarco DP, Close DA, Strock CJ, Johnston PA. Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen. Assay Drug Dev Technol. 2016 Oct;14(8):453-477. doi: 10.1089/adt.2016.741. PubMed PMID: 27606620; PMCID: PMC5067810.
Jang S, Lewis TS, Powers C, Khuchua Z, Baines CP, Wipf P, Javadov S. Elucidating Mitochondrial Electron Transport Chain Supercomplexes in the Heart During Ischemia-Reperfusion. Antioxid Redox Signal. 2017 Jul 1;27(1):57-69. doi: 10.1089/ars.2016.6635. PubMed PMID: 27604998; PMCID: PMC5488255.
Brufsky AM, Ormerod C, Bell Dickson R, Citron ML. Understanding the Needs of Patients with Metastatic Breast Cancer: Results of the Make Your Dialogue Count Survey. Breast J. 2017 Jan;23(1):17-25. doi: 10.1111/tbj.12675. PubMed PMID: 27623209.
Pollack IF, Jakacki RI, Butterfield LH, Hamilton RL, Panigrahy A, Normolle DP, Connelly AK, Dibridge S, Mason G, Whiteside TL, Okada H. Antigen-specific immunoreactivity and clinical outcome following vaccination with glioma-associated antigen peptides in children with recurrent high-grade gliomas: results of a pilot study. J Neurooncol. 2016 Dec;130(3):517-527. doi: 10.1007/s11060-016-2245-3. PubMed PMID: 27624914; PMCID: PMC5363717.
Manos-Turvey A, Al-Ashtal HA, Needham PG, Hartline CB, Prichard MN, Wipf P, Brodsky JL. Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5087-5091. doi: 10.1016/j.bmcl.2016.08.080. PubMed PMID: 27624078; PMCID: PMC5050167.
Albrecht TA, Boyiadzis M, Elswick RK Jr, Starkweather A, Rosenzweig M. Symptom Management and Psychosocial Needs of Adults With Acute Myeloid Leukemia During Induction Treatment: A Pilot Study. Cancer Nurs. 2017 Nov/Dec;40(6):E31-E38. doi: 10.1097/NCC.0000000000000428. PubMed PMID: 27631113; PMCID: PMC5350068.
Hanna RD, Naro Y, Deiters A, Floreancig PE. Alcohol, Aldehyde, and Ketone Liberation and Intracellular Cargo Release through Peroxide-Mediated α-Boryl Ether Fragmentation. J Am Chem Soc. 2016 Oct 12;138(40):13353-13360. doi: 10.1021/jacs.6b07890. PubMed PMID: 27636404.
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Goyal A, Yu FTH, Tenwalde MG, Chen X, Althouse A, Villanueva FS, Pacella JJ. Inertial Cavitation Ultrasound with Microbubbles Improves Reperfusion Efficacy When Combined with Tissue Plasminogen Activator in an In Vitro Model of Microvascular Obstruction. Ultrasound Med Biol. 2017 Jul;43(7):1391-1400. doi: 10.1016/j.ultrasmedbio.2017.02.013. PubMed PMID: 28395964; PMCID: PMC5440195.
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Kunos CA, Chu E, Makower D, Kaubisch A, Sznol M, Ivy SP. Phase I Trial of Triapine-Cisplatin-Paclitaxel Chemotherapy for Advanced Stage or Metastatic Solid Tumor Cancers. Front Oncol. 2017;762. doi: 10.3389/fonc.2017.00062. PubMed PMID: 28421163; PMCID: PMC5378786.
Koleck TA, Bender CM, Clark BZ, Ryan CM, Ghotkar P, Brufsky A, McAuliffe PF, Rastogi P, Sereika SM, Conley YP. An exploratory study of host polymorphisms in genes that clinically characterize breast cancer tumors and pretreatment cognitive performance in breast cancer survivors. Breast Cancer (Dove Med Press). 2017;995-110. doi: 10.2147/BCTT.S123785. PubMed PMID: 28424560; PMCID: PMC5344452.
Lian J, Chen J, Yuan Y, Chen J, Daud M Sayed M, Luo L, Zhu Y, Li S, Bu S. Cortex Mori Radicis extract attenuates myocardial damages in diabetic rats by regulating ERS. Biomed Pharmacother. 2017 Jun;90777-785. doi: 10.1016/j.biopha.2017.03.097. PubMed PMID: 28427040.
Rwigema JM, Choi J, Lee NY, Heron DE, Chen AM. Re-Irradiation Therapy for Locally Recurrent Head and Neck Cancer: A National Survey of Practice Patterns. Cancer Invest. 2017 Jul 3;35(6):393-402. doi: 10.1080/07357907.2017.1310222. PubMed PMID: 28437131.
Im A, Pavletic SZ. Immunotherapy in hematologic malignancies: past, present, and future. J Hematol Oncol. 2017 Apr 24;10(1):94. doi: 10.1186/s13045-017-0453-8. PubMed PMID: 28434396; PMCID: PMC5402171.
Siegfried JM, Farooqui M, Rothenberger NJ, Dacic S, Stabile LP. Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer. Oncotarget. 2017 Apr 11;8(15):24063-24076. doi: 10.18632/oncotarget.16030. PubMed PMID: 28445992; PMCID: PMC5421827.
Lohmann AE, Liebman MF, Brien W, Parulekar WR, Gelmon KA, Shepherd LE, Ligibel JA, Hershman DL, Rastogi P, Mayer IA, Hobday TJ, Lemieux J, Thompson AM, Pritchard KI, Whelan TJ, Mukherjee SD, Chalchal HI, Bernstein V, Stambolic V, Chen BE, Goodwin PJ, From the CCTG, Alliance, SWOG, ECOG, NSABP Cooperative Groups.. Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32. Breast Cancer Res Treat. 2017 Jul;164(2):371-378. doi: 10.1007/s10549-017-4265-x. PubMed PMID: 28447237; PMCID: PMC5798974.
Hepel JT, Heron DE, Mundt AJ, Yashar C, Feigenberg S, Koltis G, Regine WF, Prasad D, Patel S, Sharma N, Hebert M, Wallis N, Kuettel M. Comparison of Onsite Versus Online Chart Reviews as Part of the American College of Radiation Oncology Accreditation Program. J Oncol Pract. 2017 May;13(5):e516-e521. doi: 10.1200/JOP.2016.015230. PubMed PMID: 28301278.
Tarhini AA, Rafique I, Floros T, Tran P, Gooding WE, Villaruz LC, Burns TF, Friedland DM, Petro DP, Farooqui M, Gomez-Garcia J, Gaither-Davis A, Dacic S, Argiris A, Socinski MA, Stabile LP, Siegfried JM. Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer. Cancer. 2017 Aug 1;123(15):2936-2944. doi: 10.1002/cncr.30717. PubMed PMID: 28472537; PMCID: PMC5517339.
Corbett DB, Rejeski WJ, Tudor-Locke C, Glynn NW, Kritchevsky SB, McDermott MM, Church TS, Fielding RA, Gill TM, King AC, Miller ME, Chen H, Pahor M, Manini TM, LIFE Study Investigators .. Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study. J Gerontol B Psychol Sci Soc Sci. 2018 Oct 10;73(8):1501-1513. doi: 10.1093/geronb/gbx051. PubMed PMID: 28482106; PMCID: PMC6178963.
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Tarhini AA, Moschos SJ, Lin Y, Lin HM, Sander C, Yin Y, Venhaus R, Gajewski TF, Kirkwood JM. Safety and efficacy of the antiganglioside GD3 antibody ecromeximab (KW2871) combined with high-dose interferon-α2b in patients with metastatic melanoma. Melanoma Res. 2017 Aug;27(4):342-350. doi: 10.1097/CMR.0000000000000353. PubMed PMID: 28489678.
Kozo D, Ross MW, Jarrah J, Barrett M, Harney RL, Courtney JB, Baburina I, Holleran JL, Beumer JH, Peters GJ, Honeywell RJ, Salamone SJ. Rapid Homogeneous Immunoassay to Quantify Gemcitabine in Plasma for Therapeutic Drug Monitoring. Ther Drug Monit. 2017 Jun;39(3):235-242. doi: 10.1097/FTD.0000000000000402. PubMed PMID: 28490046; PMCID: PMC5460533.
Li Z, Fan EK, Liu J, Scott MJ, Li Y, Li S, Xie W, Billiar TR, Wilson MA, Jiang Y, Wang P, Fan J. Cold-inducible RNA-binding protein through TLR4 signaling induces mitochondrial DNA fragmentation and regulates macrophage cell death after trauma. Cell Death Dis. 2017 May 11;8(5):e2775. doi: 10.1038/cddis.2017.187. PubMed PMID: 28492546; PMCID: PMC5584526.
Sun J, Liu Y, Chen Y, Zhao W, Zhai Q, Rathod S, Huang Y, Tang S, Kwon YT, Fernandez C, Venkataramanan R, Li S. Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy. J Control Release. 2017 Jul 28;25843-55. doi: 10.1016/j.jconrel.2017.05.006. PubMed PMID: 28501705; PMCID: PMC5525542.
Sun JJ, Chen YC, Huang YX, Zhao WC, Liu YH, Venkataramanan R, Lu BF, Li S. Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier. Acta Pharmacol Sin. 2017 Jun;38(6):823-834. doi: 10.1038/aps.2017.44. PubMed PMID: 28504251; PMCID: PMC5520195.
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Ankenbruck N, Courtney T, Naro Y, Deiters A. Optochemical Control of Biological Processes in Cells and Animals. Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2768-2798. doi: 10.1002/anie.201700171. PubMed PMID: 28521066; PMCID: PMC6026863.
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Huyett P, Kim S, Johnson JT, Soose RJ. Obstructive sleep apnea in the irradiated head and neck cancer patient. Laryngoscope. 2017 Nov;127(11):2673-2677. doi: 10.1002/lary.26674. PubMed PMID: 28543072.
Pili R, Jegede O, Carducci MA, Manola J, Groteluschen DL, Appleman LL, Liu G, Shanks JC, Dakhil SR, Dutcher J, DiPaola RS. A Randomized Phase II Study to Determine the Effect of 2 Different Doses of Aflibercept in Patients With Metastatic Renal Cell Carcinoma (ECOG-ACRIN [E4805]). Clin Genitourin Cancer. 2017 Dec;15(6):642-651.e1. doi: 10.1016/j.clgc.2017.04.023. PubMed PMID: 28545998; PMCID: PMC5675826.
Farrugia DJ, Landmann A, Zhu L, Diego EJ, Johnson RR, Bonaventura M, Soran A, Dabbs DJ, Clark BZ, Puhalla SL, Jankowitz RC, Brufsky AM, Lembersky BC, Ahrendt GM, McAuliffe PF, Bhargava R. Magee Equation 3 predicts pathologic response to neoadjuvant systemic chemotherapy in estrogen receptor positive, HER2 negative/equivocal breast tumors. Mod Pathol. 2017 Aug;30(8):1078-1085. doi: 10.1038/modpathol.2017.41. PubMed PMID: 28548119.
Boele FW, van Uden-Kraan CF, Hilverda K, Weimer J, Donovan HS, Drappatz J, Lieberman FS, Verdonck-de Leeuw I, Sherwood PR. Neuro-oncology family caregivers' view on keeping track of care issues using eHealth systems: it's a question of time. J Neurooncol. 2017 Aug;134(1):157-167. doi: 10.1007/s11060-017-2504-y. PubMed PMID: 28550505; PMCID: PMC5543187.
Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA. Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity. Cell. 2017 Jun 1;169(6):1130-1141.e11. doi: 10.1016/j.cell.2017.05.005. PubMed PMID: 28552348; PMCID: PMC5509332.
Atreya CE, Yaeger R, Chu E. Systemic Therapy for Metastatic Colorectal Cancer: From Current Standards to Future Molecular Targeted Approaches. Am Soc Clin Oncol Educ Book. 2017;37246-256. doi: 10.14694/EDBK_175679. PubMed PMID: 28561718.
Bian Y, Feng Z, Yang P, Xie XQ. Integrated In Silico Fragment-Based Drug Design: Case Study with Allosteric Modulators on Metabotropic Glutamate Receptor 5. AAPS J. 2017 Jul;19(4):1235-1248. doi: 10.1208/s12248-017-0093-5. PubMed PMID: 28560482; PMCID: PMC5836546.
Cui H, Gu X, Chen J, Xie Y, Ke S, Wu J, Golovko A, Morpurgo B, Yan C, Phillips TD, Xie W, Luo J, Zhou Z, Tian Y. Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage. Toxicol Lett. 2017 Jun 5;27567-76. doi: 10.1016/j.toxlet.2017.03.028. PubMed PMID: 28428138.
Roy A, Ye J, Deng F, Wang QJ. Protein kinase D signaling in cancer: A friend or foe? Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):283-294. doi: 10.1016/j.bbcan.2017.05.008. PubMed PMID: 28577984; PMCID: PMC5548606.
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Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duffy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhoff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taube J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW, Eshleman JR, Vogelstein B, Anders RA, Diaz LA Jr. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science. 2017 Jul 28;357(6349):409-413. doi: 10.1126/science.aan6733. PubMed PMID: 28596308; PMCID: PMC5576142.
Luo J, Torres-Kolbus J, Liu J, Deiters A. Genetic Encoding of Photocaged Tyrosines with Improved Light-Activation Properties for the Optical Control of Protease Function. Chembiochem. 2017 Jul 18;18(14):1442-1447. doi: 10.1002/cbic.201700147. PubMed PMID: 28608946.
Hukriede N, Vogt A, de Caestecker M. Drug Discovery to Halt the Progression of Acute Kidney Injury to Chronic Kidney Disease: A Case for Phenotypic Drug Discovery in Acute Kidney Injury. Nephron. 2017;137(4):268-272. doi: 10.1159/000476079. PubMed PMID: 28614822.
Liu K, Zhu J, Huang Y, Li C, Lu J, Sachar M, Li S, Ma X. Metabolism of KO143, an ABCG2 inhibitor. Drug Metab Pharmacokinet. 2017 Aug;32(4):193-200. doi: 10.1016/j.dmpk.2017.02.003. PubMed PMID: 28619281.
Carbone DP, Reck M, Paz-Ares L, Creelan B, Horn L, Steins M, Felip E, van den Heuvel MM, Ciuleanu TE, Badin F, Ready N, Hiltermann TJN, Nair S, Juergens R, Peters S, Minenza E, Wrangle JM, Rodriguez-Abreu D, Borghaei H, Blumenschein GR Jr, Villaruz LC, Havel L, Krejci J, Corral Jaime J, Chang H, Geese WJ, Bhagavatheeswaran P, Chen AC, Socinski MA, CheckMate 026 Investigators.. First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer. N Engl J Med. 2017 Jun 22;376(25):2415-2426. doi: 10.1056/NEJMoa1613493. PubMed PMID: 28636851; PMCID: PMC6487310.
Allen TH, Kawamoto T, Gardner S, Geib SJ, Curran DP. N-Heterocyclic Carbene Boryl Iodides Catalyze Insertion Reactions of N-Heterocyclic Carbene Boranes and Diazoesters. Org Lett. 2017 Jul 7;19(13):3680-3683. doi: 10.1021/acs.orglett.7b01777. PubMed PMID: 28641014.
Sant S, Johnston PA. The production of 3D tumor spheroids for cancer drug discovery. Drug Discov Today Technol. 2017 Mar;2327-36. doi: 10.1016/j.ddtec.2017.03.002. PubMed PMID: 28647083; PMCID: PMC5497458.
Liu J, Hemphill J, Samanta S, Tsang M, Deiters A. Genetic Code Expansion in Zebrafish Embryos and Its Application to Optical Control of Cell Signaling. J Am Chem Soc. 2017 Jul 12;139(27):9100-9103. doi: 10.1021/jacs.7b02145. PubMed PMID: 28657738; PMCID: PMC6022368.
Masoodi KZ, Xu Y, Dar JA, Eisermann K, Pascal LE, Parrinello E, Ai J, Johnston PA, Nelson JB, Wipf P, Wang Z. Inhibition of Androgen Receptor Nuclear Localization and Castration-Resistant Prostate Tumor Growth by Pyrroloimidazole-based Small Molecules. Mol Cancer Ther. 2017 Oct;16(10):2120-2129. doi: 10.1158/1535-7163.MCT-17-0176. PubMed PMID: 28655783; PMCID: PMC5628124.
Lim MJ, Agha A, Im A, Raptis A, Hou JZ, Boyiadzis M, Sehgal AR, Redner RL, Dorritie K, Marks SS, Agha ME, Lim SH. Intensive induction chemotherapy vs hypomethylating agent-based regimen in patients aged ≥70 years with newly diagnosed acute myeloid leukemia. Hematol Oncol. 2018 Apr;36(2):495-497. doi: 10.1002/hon.2456. PubMed PMID: 28664979.
Mathew A, Brufsky A. TACT2: improving treatment tolerability in early breast cancer. Lancet Oncol. 2017 Jul;18(7):843-845. doi: 10.1016/S1470-2045(17)30437-0. PubMed PMID: 28677561.
Nientiedt C, Heller M, Endris V, Volckmar AL, Zschäbitz S, Tapia-Laliena MA, Duensing A, Jäger D, Schirmacher P, Sültmann H, Stenzinger A, Hohenfellner M, Grüllich C, Duensing S. Mutations in BRCA2 and taxane resistance in prostate cancer. Sci Rep. 2017 Jul 4;7(1):4574. doi: 10.1038/s41598-017-04897-x. PubMed PMID: 28676659; PMCID: PMC5496866.
Epelboym I, Zenati MS, Hamad A, Steve J, Lee KK, Bahary N, Hogg ME, Zeh HJ, Zureikat AH. Analysis of Perioperative Chemotherapy in Resected Pancreatic Cancer: Identifying the Number and Sequence of Chemotherapy Cycles Needed to Optimize Survival. Ann Surg Oncol. 2017 Sep;24(9):2744-2751. doi: 10.1245/s10434-017-5975-3. PubMed PMID: 28681155.
Husain AN, Colby TV, Ordóñez NG, Allen TC, Attanoos RL, Beasley MB, Butnor KJ, Chirieac LR, Churg AM, Dacic S, Galateau-Sallé F, Gibbs A, Gown AM, Krausz T, Litzky LA, Marchevsky A, Nicholson AG, Roggli VL, Sharma AK, Travis WD, Walts AE, Wick MR. Guidelines for Pathologic Diagnosis of Malignant Mesothelioma 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group. Arch Pathol Lab Med. 2018 Jan;142(1):89-108. doi: 10.5858/arpa.2017-0124-RA. PubMed PMID: 28686500.
Sen M, Johnston PA, Pollock NI, DeGrave K, Joyce SC, Freilino ML, Hua Y, Camarco DP, Close DA, Huryn DM, Wipf P, Grandis JR. Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines. J Chem Biol. 2017 Jul;10(3):129-141. doi: 10.1007/s12154-017-0169-9. PubMed PMID: 28684999; PMCID: PMC5480263.
Kooiman K, van Rooij T, Qin B, Mastik F, Vos HJ, Versluis M, Klibanov AL, de Jong N, Villanueva FS, Chen X. Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification. PLoS One. 2017;12(7):e0180747. doi: 10.1371/journal.pone.0180747. PubMed PMID: 28686673; PMCID: PMC5501608.
Rohrs TM, Qin Q, Floreancig PE. Re2 O7 -Mediated Dehydrative Cyclization Reactions: Total Synthesis of Herboxidiene and Its 12-Desmethyl Analogue. Angew Chem Int Ed Engl. 2017 Aug 28;56(36):10900-10904. doi: 10.1002/anie.201705924. PubMed PMID: 28686815; PMCID: PMC5687070.
Lontos K, Agha M, Raptis A, Hou JZ, Farah R, Redner RL, Im A, Dorritie KA, Sehgal A, Rossetti J, Saul M, Gooding WE, Humar A, Boyiadzis M. Outcomes of patients diagnosed with acute myeloid leukemia after solid organ transplantation. Clin Transplant. 2017 Sep;31(9): doi: 10.1111/ctr.13052. PubMed PMID: 28710776.
Hartman DJ, Borczuk A, Dacic S, Krasinskas A. Reproducibility for histologic parameters in peritoneal mesothelioma. Hum Pathol. 2017 Sep;6754-59. doi: 10.1016/j.humpath.2017.07.005. PubMed PMID: 28712777.
Brufsky AM. Long-term management of patients with hormone receptor-positive metastatic breast cancer: Concepts for sequential and combination endocrine-based therapies. Cancer Treat Rev. 2017 Sep;5922-32. doi: 10.1016/j.ctrv.2017.06.004. PubMed PMID: 28719836.
Porteous MK, Lee JC, Lederer DJ, Palmer SM, Cantu E, Shah RJ, Bellamy SL, Lama VN, Bhorade SM, Crespo MM, McDyer JF, Wille KM, Localio AR, Orens JB, Shah PD, Weinacker AB, Arcasoy S, Wilkes DS, Ware LB, Christie JD, Kawut SM, Diamond JM, Lung Transplant Outcomes Group.. Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension. Ann Am Thorac Soc. 2017 Oct;14(10):1514-1522. doi: 10.1513/AnnalsATS.201610-810OC. PubMed PMID: 28719755; PMCID: PMC5718566.
Appleman LJ, Maranchie JK. Systemic therapy following metastasectomy for renal cell carcinoma: Using insights from other clinical settings to address unanswered questions. Urol Oncol. 2018 Jan;36(1):17-22. doi: 10.1016/j.urolonc.2017.06.005. PubMed PMID: 28736252.
Nguyen KT, Kalyan A, Beasley HS, Singhi AD, Sun W, Zeh HJ, Normolle D, Bahary N. Gemcitabine/nab-paclitaxel as second-line therapy following FOLFIRINOX in metastatic/advanced pancreatic cancer-retrospective analysis of response. J Gastrointest Oncol. 2017 Jun;8(3):556-565. doi: 10.21037/jgo.2017.01.23. PubMed PMID: 28736642; PMCID: PMC5506273.
Zheng Z, Zhao Z, Li S, Lu X, Jiang M, Lin J, An Y, Xie Y, Xu M, Shen W, Guo GL, Huang Y, Li S, Zhang X, Xie W. Altenusin, a Nonsteroidal Microbial Metabolite, Attenuates Nonalcoholic Fatty Liver Disease by Activating the Farnesoid X Receptor. Mol Pharmacol. 2017 Oct;92(4):425-436. doi: 10.1124/mol.117.108829. PubMed PMID: 28739572; PMCID: PMC5588546.
Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY. p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis. Nat Commun. 2017 Jul 24;8(1):102. doi: 10.1038/s41467-017-00085-7. PubMed PMID: 28740232; PMCID: PMC5524641.
Kubik M, Mandal R, Albergotti W, Duvvuri U, Ferris RL, Kim S. Effect of transcervical arterial ligation on the severity of postoperative hemorrhage after transoral robotic surgery. Head Neck. 2017 Aug;39(8):1510-1515. doi: 10.1002/hed.24677. PubMed PMID: 28570011; PMCID: PMC5789773.
Mathew A, Rajagopal PS, Villgran V, Sandhu GS, Jankowitz RC, Jacob M, Rosenzweig M, Oesterreich S, Brufsky A. Distinct Pattern of Metastases in Patients with Invasive Lobular Carcinoma of the Breast. Geburtshilfe Frauenheilkd. 2017 Jun;77(6):660-666. doi: 10.1055/s-0043-109374. PubMed PMID: 28757653; PMCID: PMC5489406.
Stoller R, Schmitz JC, Ding F, Puhalla S, Belani CP, Appleman L, Lin Y, Jiang Y, Almokadem S, Petro D, Holleran J, Kiesel BF, Ken Czambel R, Carneiro BA, Kontopodis E, Hershberger PA, Rachid M, Chen A, Chu E, Beumer JH. Phase I study of veliparib in combination with gemcitabine. Cancer Chemother Pharmacol. 2017 Sep;80(3):631-643. doi: 10.1007/s00280-017-3409-3. PubMed PMID: 28770300; PMCID: PMC5734661.
Schenker Y, Bahary N, Claxton R, Childers J, Chu E, Kavalieratos D, King L, Lembersky B, Tiver G, Arnold RM. A Pilot Trial of Early Specialty Palliative Care for Patients with Advanced Pancreatic Cancer: Challenges Encountered and Lessons Learned. J Palliat Med. 2018 Jan;21(1):28-36. doi: 10.1089/jpm.2017.0113. PubMed PMID: 28772092; PMCID: PMC5757080.
Tonetti DA, Ares WJ, Richardson RM, Hamilton RL, Lieberman FS. Long-term recurrence of dysembryoplastic neuroepithelial tumor: Clinical case report. Surg Neurol Int. 2017;8140. doi: 10.4103/2152-7806.210257. PubMed PMID: 28781917; PMCID: PMC5523508.
Zhang Q, Chikina M, Szymczak-Workman AL, Horne W, Kolls JK, Vignali KM, Normolle D, Bettini M, Workman CJ, Vignali DAA. LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes. Sci Immunol. 2017 Mar 31;2(9): doi: 10.1126/sciimmunol.aah4569. PubMed PMID: 28783703; PMCID: PMC5609824.
Marchevsky AM, LeStang N, Hiroshima K, Pelosi G, Attanoos R, Churg A, Chirieac L, Dacic S, Husain A, Khoor A, Klebe S, Lantuejoul S, Roggli V, Vignaud JM, Weynard B, Sauter J, Henderson D, Nabeshima K, Galateau-Salle F. The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center. Hum Pathol. 2017 Sep;67160-168. doi: 10.1016/j.humpath.2017.07.015. PubMed PMID: 28782639.
Hamad A, Singhi AD, Bahary N, McGrath K, Amarin R, Zeh HJ, Zureikat AH. Neoadjuvant Treatment With Trastuzumab and FOLFOX Induces a Complete Pathologic Response in a Metastatic ERBB2 (HER2)-Amplified Duodenal Cancer. J Natl Compr Canc Netw. 2017 Aug;15(8):983-988. doi: 10.6004/jnccn.2017.0140. PubMed PMID: 28784859.
Feng M, Suresh K, Schipper MJ, Bazzi L, Ben-Josef E, Matuszak MM, Parikh ND, Welling TH, Normolle D, Ten Haken RK, Lawrence TS. Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage: A Phase 2 Clinical Trial. JAMA Oncol. 2018 Jan 1;4(1):40-47. doi: 10.1001/jamaoncol.2017.2303. PubMed PMID: 28796864; PMCID: PMC5766368.
Schroeder B, Zhang Y, Stål O, Fornander T, Brufsky A, Sgroi DC, Schnabel CA. Risk stratification with Breast Cancer Index for late distant recurrence in patients with clinically low-risk (T1N0) estrogen receptor-positive breast cancer. NPJ Breast Cancer. 2017;328. doi: 10.1038/s41523-017-0037-3. PubMed PMID: 28795152; PMCID: PMC5543049.
Li J, Ghazwani M, Liu K, Huang Y, Chang N, Fan J, He F, Li L, Bu S, Xie W, Ma X, Li S. Regulation of hepatic stellate cell proliferation and activation by glutamine metabolism. PLoS One. 2017;12(8):e0182679. doi: 10.1371/journal.pone.0182679. PubMed PMID: 28797105; PMCID: PMC5552314.
Matsushita N, Hassanein MT, Martinez-Clemente M, Lazaro R, French SW, Xie W, Lai K, Karin M, Tsukamoto H. Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1. PLoS One. 2017;12(8):e0181052. doi: 10.1371/journal.pone.0181052. PubMed PMID: 28797077; PMCID: PMC5552280.
Shun T, Gough AH, Sanker S, Hukriede NA, Vogt A. Exploiting Analysis of Heterogeneity to Increase the Information Content Extracted from Fluorescence Micrographs of Transgenic Zebrafish Embryos. Assay Drug Dev Technol. 2017 Aug/Sep;15(6):257-266. doi: 10.1089/adt.2017.793. PubMed PMID: 28800244; PMCID: PMC5576098.
Curtis LM, Pirsl F, Steinberg SM, Mitchell SA, Baird K, Cowen EW, Mays J, Buxbaum NP, Pichard DC, Im A, Avila D, Taylor T, Fowler DH, Gress RE, Pavletic SZ. Predictors for Permanent Discontinuation of Systemic Immunosuppression in Severely Affected Chronic Graft-Versus-Host Disease Patients. Biol Blood Marrow Transplant. 2017 Nov;23(11):1980-1988. doi: 10.1016/j.bbmt.2017.08.005. PubMed PMID: 28797782.
Albergotti WG, Jordan J, Anthony K, Abberbock S, Wasserman-Wincko T, Kim S, Ferris RL, Duvvuri U. A prospective evaluation of short-term dysphagia after transoral robotic surgery for squamous cell carcinoma of the oropharynx. Cancer. 2017 Aug 15;123(16):3132-3140. doi: 10.1002/cncr.30712. PubMed PMID: 28467606; PMCID: PMC5544540.
Kikuchi M, Clump DA, Srivastava RM, Sun L, Zeng D, Diaz-Perez JA, Anderson CJ, Edwards WB, Ferris RL. Preclinical immunoPET/CT imaging using Zr-89-labeled anti-PD-L1 monoclonal antibody for assessing radiation-induced PD-L1 upregulation in head and neck cancer and melanoma. Oncoimmunology. 2017;6(7):e1329071. doi: 10.1080/2162402X.2017.1329071. PubMed PMID: 28811971; PMCID: PMC5543907.
Xu J, Wipf P. Indole synthesis by palladium-catalyzed tandem allylic isomerization - furan Diels-Alder reaction. Org Biomol Chem. 2017 Aug 30;15(34):7093-7096. doi: 10.1039/c7ob01654a. PubMed PMID: 28813061.
Tarhini AA, Floros T, Lin HM, Lin Y, Rahman Z, Ashraf M, Vallabhaneni P, Sander C, Rao UNM, Panelli M, LaFramboise WA, Kirkwood JM. A unique gene expression signature is significantly differentially expressed in tumor-positive or tumor-negative sentinel lymph nodes in patients with melanoma. Melanoma Res. 2017 Oct;27(5):429-438. doi: 10.1097/CMR.0000000000000383. PubMed PMID: 28825947; PMCID: PMC5657445.
Gleixner AM, Hutchison DF, Sannino S, Bhatia TN, Leak LC, Flaherty PT, Wipf P, Brodsky JL, Leak RK. N-Acetyl-l-Cysteine Protects Astrocytes against Proteotoxicity without Recourse to Glutathione. Mol Pharmacol. 2017 Nov;92(5):564-575. doi: 10.1124/mol.117.109926. PubMed PMID: 28830914; PMCID: PMC5635514.
Sanei-Moghaddam A, Kang C, Edwards RP, Lounder PJ, Ismail N, Goughnour SL, Mansuria SM, Comerci JT, Linkov F. Racial and Socioeconomic Disparities in Hysterectomy Route for Benign Conditions. J Racial Ethn Health Disparities. 2018 Aug;5(4):758-765. doi: 10.1007/s40615-017-0420-7. PubMed PMID: 28840507.
Mathew A, Achkar T, Abberbock S, Sandhu GS, Jacob ME, Villgran VD, Rosenzweig MQ, Puhalla S, Brufsky AM. Prevalence and determinants of end-of-life chemotherapy use in patients with metastatic breast cancer. Breast J. 2017 Nov;23(6):718-722. doi: 10.1111/tbj.12905. PubMed PMID: 28845536; PMCID: PMC5675818.
Weller M, Butowski N, Tran DD, Recht LD, Lim M, Hirte H, Ashby L, Mechtler L, Goldlust SA, Iwamoto F, Drappatz J, O'Rourke DM, Wong M, Hamilton MG, Finocchiaro G, Perry J, Wick W, Green J, He Y, Turner CD, Yellin MJ, Keler T, Davis TA, Stupp R, Sampson JH, ACT IV trial investigators.. Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial. Lancet Oncol. 2017 Oct;18(10):1373-1385. doi: 10.1016/S1470-2045(17)30517-X. PubMed PMID: 28844499.
Zhai Q, Chen Y, Xu J, Huang Y, Sun J, Liu Y, Zhang X, Li S, Tang S. Lymphoma Immunochemotherapy: Targeted Delivery of Doxorubicin via a Dual Functional Nanocarrier. Mol Pharm. 2017 Nov 6;14(11):3888-3895. doi: 10.1021/acs.molpharmaceut.7b00606. PubMed PMID: 28850241.
Helfield BL, Chen X, Qin B, Watkins SC, Villanueva FS. Mechanistic Insight into Sonoporation with Ultrasound-Stimulated Polymer Microbubbles. Ultrasound Med Biol. 2017 Nov;43(11):2678-2689. doi: 10.1016/j.ultrasmedbio.2017.07.017. PubMed PMID: 28847500; PMCID: PMC5644032.
Lieberman F, Villgran V, Normolle D, Boyiadzis M. Intracranial Hemorrhage in Patients Newly Diagnosed with Acute Myeloid Leukemia and Hyperleukocytosis. Acta Haematol. 2017;138(2):116-118. doi: 10.1159/000478690. PubMed PMID: 28858876.
Boyiadzis M, Agha M, Redner RL, Sehgal A, Im A, Hou JZ, Farah R, Dorritie KA, Raptis A, Lim SH, Wang H, Lapteva N, Mei Z, Butterfield LH, Rooney CM, Whiteside TL. Phase 1 clinical trial of adoptive immunotherapy using "off-the-shelf" activated natural killer cells in patients with refractory and relapsed acute myeloid leukemia. Cytotherapy. 2017 Oct;19(10):1225-1232. doi: 10.1016/j.jcyt.2017.07.008. PubMed PMID: 28864289.
Ward MC, Riaz N, Caudell JJ, Dunlap NE, Isrow D, Zakem SJ, Dault J, Awan MJ, Vargo JA, Heron DE, Higgins KA, Beitler JJ, Marcrom S, Boggs DH, Hassanzadeh C, Reddy CA, Bonner JA, Yao M, Machtay M, Siddiqui F, Trotti AM, Lee NY, Koyfman SA, Multi-Institution Reirradiation (MIRI) Collaborative.. Refining Patient Selection for Reirradiation of Head and Neck Squamous Carcinoma in the IMRT Era: A Multi-institution Cohort Study by the MIRI Collaborative. Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):586-594. doi: 10.1016/j.ijrobp.2017.06.012. PubMed PMID: 28865925.
Chen KS, Berhane H, Gill BS, Olawaiye A, Sukumvanich P, Kelley JL, Boisen MM, Courtney-Brooks M, Comerci JT, Edwards R, Berger J, Beriwal S. Outcomes of stage II endometrial cancer: The UPMC Hillman Cancer Center experience. Gynecol Oncol. 2017 Nov;147(2):315-319. doi: 10.1016/j.ygyno.2017.08.021. PubMed PMID: 28866431.
Karukonda P, Gebhardt BJ, Horne ZD, Heron DE, Beriwal S. Standardization of radiation therapy dose for locally advanced non-small cell lung cancer through changes to a lung cancer clinical pathway in a large, integrated comprehensive cancer center network. Pract Radiat Oncol. 2017 Nov - Dec;7(6):e551-e557. doi: 10.1016/j.prro.2017.07.003. PubMed PMID: 28867544.
Ma L, Ni H, Zou X, Yuan Y, Luo C, Liu B, Wang F, Xi Y, Chu Y, Xu P, Qiu X, Li S, Bu S. Mori cortex prevents kidney damage through inhibiting expression of inflammatory factors in the glomerulus in streptozocin-induced diabetic rats. Iran J Basic Med Sci. 2017 Jun;20(6):715-721. doi: 10.22038/IJBMS.2017.8842. PubMed PMID: 28868127; PMCID: PMC5569450.
Matsumoto J, Kiesel BF, Parise RA, Guo J, Taylor S, Huang M, Eiseman JL, Ivy SP, Kunos C, Chu E, Beumer JH. LC-MS/MS assay for the quantitation of the ribonucleotide reductase inhibitor triapine in human plasma. J Pharm Biomed Anal. 2017 Nov 30;146154-160. doi: 10.1016/j.jpba.2017.08.036. PubMed PMID: 28881312; PMCID: PMC5636190.
Priedigkeit N, Watters RJ, Lucas PC, Basudan A, Bhargava R, Horne W, Kolls JK, Fang Z, Rosenzweig MQ, Brufsky AM, Weiss KR, Oesterreich S, Lee AV. Exome-capture RNA sequencing of decade-old breast cancers and matched decalcified bone metastases. JCI Insight. 2017 Sep 7;2(17): doi: 10.1172/jci.insight.95703. PubMed PMID: 28878133; PMCID: PMC5621874.
Kiesel BF, Scemama J, Parise RA, Villaruz L, Iffland A, Doyle A, Ivy P, Chu E, Bakkenist CJ, Beumer JH. LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma. J Pharm Biomed Anal. 2017 Nov 30;146244-250. doi: 10.1016/j.jpba.2017.08.037. PubMed PMID: 28888173; PMCID: PMC5632222.
Ocuin LM, Miller-Ocuin JL, Zenati MS, Vargo JA, Singhi AD, Burton SA, Bahary N, Hogg ME, Zeh HJ 3rd, Zureikat AH. A margin distance analysis of the impact of adjuvant chemoradiation on survival after pancreatoduodenectomy for pancreatic adenocarcinoma. J Gastrointest Oncol. 2017 Aug;8(4):696-704. doi: 10.21037/jgo.2017.04.02. PubMed PMID: 28890820; PMCID: PMC5582038.
Gadzinski JA, Guo J, Philips BJ, Basse P, Craig EK, Bailey L, Comerci JT, Eiseman JL. Evaluation of Silicon Phthalocyanine 4 Photodynamic Therapy Against Human Cervical Cancer Cells In Vitro and in Mice. Adv Biol Chem. 2016 Dec;6(6):193-215. doi: 10.4236/abc.2016.66017. PubMed PMID: 28890844; PMCID: PMC5589197.
Kansy BA, Concha-Benavente F, Srivastava RM, Jie HB, Shayan G, Lei Y, Moskovitz J, Moy J, Li J, Brandau S, Lang S, Schmitt NC, Freeman GJ, Gooding WE, Clump DA, Ferris RL. PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer. Cancer Res. 2017 Nov 15;77(22):6353-6364. doi: 10.1158/0008-5472.CAN-16-3167. PubMed PMID: 28904066; PMCID: PMC5690836.
Godse NR, Khan N, Yochum ZA, Gomez-Casal R, Kemp C, Shiwarski DJ, Seethala RS, Kulich S, Seshadri M, Burns TF, Duvvuri U. TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression. Clin Cancer Res. 2017 Dec 1;23(23):7324-7332. doi: 10.1158/1078-0432.CCR-17-1561. PubMed PMID: 28899969; PMCID: PMC5898434.
Vargo JA, Ward MC, Caudell JJ, Riaz N, Dunlap NE, Isrow D, Zakem SJ, Dault J, Awan MJ, Higgins KA, Hassanadeh C, Beitler JJ, Reddy CA, Marcrom S, Boggs DH, Bonner JA, Yao M, Machtay M, Siddiqui F, Trotti AM, Lee NY, Koyfman SA, Ferris RL, Heron DE. A Multi-institutional Comparison of SBRT and IMRT for Definitive Reirradiation of Recurrent or Second Primary Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):595-605. doi: 10.1016/j.ijrobp.2017.04.017. PubMed PMID: 28899556.
Wang J, Heng YJ, Eliassen AH, Tamimi RM, Hazra A, Carey VJ, Ambrosone CB, de Andrade VP, Brufsky A, Couch FJ, King TA, Modugno F, Vachon CM, Hunter DJ, Beck AH, Hankinson SE. Alcohol consumption and breast tumor gene expression. Breast Cancer Res. 2017 Sep 12;19(1):108. doi: 10.1186/s13058-017-0901-y. PubMed PMID: 28899409; PMCID: PMC5596493.
Schirda CV, Zhao T, Yushmanov VE, Lee Y, Ghearing GR, Lieberman FS, Panigrahy A, Hetherington HP, Pan JW. Fast 3D rosette spectroscopic imaging of neocortical abnormalities at 3 T: Assessment of spectral quality. Magn Reson Med. 2018 May;79(5):2470-2480. doi: 10.1002/mrm.26901. PubMed PMID: 28905419; PMCID: PMC5821598.
Kota K, Brufsky A, Oesterreich S, Lee A. Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification. Cureus. 2017 Jul 6;9(7):e1434. doi: 10.7759/cureus.1434. PubMed PMID: 28924522; PMCID: PMC5587405.
Gebhardt B, Gill B, Glaser S, Kim H, Houser C, Kelley J, Sukumvanich P, Edwards R, Comerci J, Olawaiye A, Courtney-Brooks M, Boisen M, Berger J, Beriwal S. Image-guided tandem and cylinder brachytherapy as monotherapy for definitive treatment of inoperable endometrial carcinoma. Gynecol Oncol. 2017 Nov;147(2):302-308. doi: 10.1016/j.ygyno.2017.09.006. PubMed PMID: 28923412.
Xue Y, Feng ZW, Li XY, Hu ZH, Xu Q, Wang Z, Cheng JH, Shi HT, Wang QB, Wu HY, Xie XQ, Lv QZ. The efficacy and safety of cilostazol as an alternative to aspirin in Chinese patients with aspirin intolerance after coronary stent implantation: a combined clinical study and computational system pharmacology analysis. Acta Pharmacol Sin. 2018 Feb;39(2):205-212. doi: 10.1038/aps.2017.85. PubMed PMID: 28933424; PMCID: PMC5800472.
Gebhardt BJ, Thomas J, Horne ZD, Champ CE, Ahrendt GM, Diego E, Heron DE, Beriwal S. Standardization of nodal radiation therapy through changes to a breast cancer clinical pathway throughout a large, integrated cancer center network. Pract Radiat Oncol. 2018 Jan - Feb;8(1):4-12. doi: 10.1016/j.prro.2017.07.012. PubMed PMID: 28939351.
Prabhu AV, Kim C, De Guzman E, Zhao E, Madill E, Cohen J, Hansberry DR, Agarwal N, Heron DE, Beriwal S. Reputation Management and Content Control: An Analysis of Radiation Oncologists' Digital Identities. Int J Radiat Oncol Biol Phys. 2017 Dec 1;99(5):1083-1091. doi: 10.1016/j.ijrobp.2017.08.015. PubMed PMID: 28939228.
Garbacz WG, Jiang M, Xu M, Yamauchi J, Dong HH, Xie W. Sex- and Tissue-Specific Role of Estrogen Sulfotransferase in Energy Homeostasis and Insulin Sensitivity. Endocrinology. 2017 Nov 1;158(11):4093-4104. doi: 10.1210/en.2017-00571. PubMed PMID: 28938414; PMCID: PMC5695832.
Gogineni E, Vargo JA, Glaser SM, Flickinger JC, Burton SA, Engh JA, Amankulor NM, Beriwal S, Quinn AE, Ozhasoglu C, Heron DE. Long-Term Survivorship Following Stereotactic Radiosurgery Alone for Brain Metastases: Risk of Intracranial Failure and Implications for Surveillance and Counseling. Neurosurgery. 2018 Aug 1;83(2):203-209. doi: 10.1093/neuros/nyx376. PubMed PMID: 28945873.
Lazo JS, McQueeney KE, Burnett JC, Wipf P, Sharlow ER. Small molecule targeting of PTPs in cancer. Int J Biochem Cell Biol. 2018 Mar;96171-181. doi: 10.1016/j.biocel.2017.09.011. PubMed PMID: 28943273.
Morihiro K, Ankenbruck N, Lukasak B, Deiters A. Small Molecule Release and Activation through DNA Computing. J Am Chem Soc. 2017 Oct 4;139(39):13909-13915. doi: 10.1021/jacs.7b07831. PubMed PMID: 28945369.
Bandos H, Melnikow J, Rivera DR, Swain SM, Sturtz K, Fehrenbacher L, Wade JL 3rd, Brufsky AM, Julian TB, Margolese RG, McCarron EC, Ganz PA. Long-term Peripheral Neuropathy in Breast Cancer Patients Treated With Adjuvant Chemotherapy: NRG Oncology/NSABP B-30. J Natl Cancer Inst. 2018 Feb 1;110(2): doi: 10.1093/jnci/djx162. PubMed PMID: 28954297; PMCID: PMC5825682.
Eiseman JL, Sciullo M, Wang H, Beumer JH, Horn CC. Estimation of body surface area in the musk shrew ( Suncus murinus): a small animal for testing chemotherapy-induced emesis. Lab Anim. 2017 Oct;51(5):534-537. doi: 10.1177/0023677217695851. PubMed PMID: 28948895; PMCID: PMC5654602.
Huryn DM, Bolognesi ML, Young WB. Medicinal Chemistry: Where Are All the Women? ACS Med Chem Lett. 2017 Sep 14;8(9):900-902. doi: 10.1021/acsmedchemlett.7b00321. PubMed PMID: 28947931; PMCID: PMC5601382.
Li Z, Jiao Y, Fan EK, Scott MJ, Li Y, Li S, Billiar TR, Wilson MA, Shi X, Fan J. Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria. J Immunol. 2017 Nov 1;199(9):3176-3186. doi: 10.4049/jimmunol.1700140. PubMed PMID: 28947541; PMCID: PMC5679440.
Luu T, Kim KP, Blanchard S, Anyang B, Hurria A, Yang L, Beumer JH, Somlo G, Yen Y. Phase IB trial of ixabepilone and vorinostat in metastatic breast cancer. Breast Cancer Res Treat. 2018 Jan;167(2):469-478. doi: 10.1007/s10549-017-4516-x. PubMed PMID: 28956187.
Wenz C, Faust D, Linz B, Turmann C, Nikolova T, Bertin J, Gough P, Wipf P, Schröder AS, Krautwald S, Dietrich C. t-BuOOH induces ferroptosis in human and murine cell lines. Arch Toxicol. 2018 Feb;92(2):759-775. doi: 10.1007/s00204-017-2066-y. PubMed PMID: 28975372.
Masoodi KZ, Eisermann K, Yang Z, Dar JA, Pascal LE, Nguyen M, O'Malley K, Parrinello E, Feturi FG, Kenefake AN, Nelson JB, Johnston PA, Wipf P, Wang Z. Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone. Endocrinology. 2017 Oct 1;158(10):3152-3161. doi: 10.1210/en.2017-00408. PubMed PMID: 28977599; PMCID: PMC5659684.
Ancevski Hunter K, Friedland DM, Villaruz LC, Burns TF. First-Line Osimertinib in Patients with Treatment-Naive Somatic or Germline EGFR T790M-Mutant Metastatic NSCLC. J Thorac Oncol. 2018 Jan;13(1):e3-e5. doi: 10.1016/j.jtho.2017.09.1963. PubMed PMID: 28989039.
Nghiemphu PL, Ebiana VA, Wen P, Gilbert M, Abrey LE, Lieberman F, DeAngelis LM, Robins HI, Yung WKA, Chang S, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados M, Kuhn J, Cloughesy TF. Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02. J Neurooncol. 2018 Jan;136(1):79-86. doi: 10.1007/s11060-017-2624-4. PubMed PMID: 28988377; PMCID: PMC5756101.
Wang N, Wang L, Xie XQ. ProSelection: A Novel Algorithm to Select Proper Protein Structure Subsets for in Silico Target Identification and Drug Discovery Research. J Chem Inf Model. 2017 Nov 27;57(11):2686-2698. doi: 10.1021/acs.jcim.7b00277. PubMed PMID: 29016123; PMCID: PMC5836547.
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Escudier B, Powles T, Motzer RJ, Olencki T, Arén Frontera O, Oudard S, Rolland F, Tomczak P, Castellano D, Appleman LJ, Drabkin H, Vaena D, Milwee S, Youkstetter J, Lougheed JC, Bracarda S, Choueiri TK. Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial. J Clin Oncol. 2018 Mar 10;36(8):765-772. doi: 10.1200/JCO.2017.74.7352. PubMed PMID: 29309249.
Huang Q, Stalnecker C, Zhang C, McDermott LA, Iyer P, O'Neill J, Reimer S, Cerione RA, Katt WP. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism. J Biol Chem. 2018 Mar 9;293(10):3535-3545. doi: 10.1074/jbc.M117.810101. PubMed PMID: 29317493; PMCID: PMC5846160.
Mehta K, Im A, Rahman F, Wang H, Veldkamp P. Epidemiology and Outcomes of Hematopoietic Stem Cell Transplantation in Human Immunodeficiency Virus-Positive Patients From 1998 to 2012: A Nationwide Analysis. Clin Infect Dis. 2018 Jun 18;67(1):128-133. doi: 10.1093/cid/ciy010. PubMed PMID: 29325063.
Schoemans HM, Goris K, Van Durm R, Vanbrabant K, De Geest S, Maertens J, Wolff D, Greinix H, Ruutu T, Pavletic SZ, Im A, Lee SJ, Basak GW, Duarte RF, Dobbels F, Complications and Quality of Life Working Party of the EBMT.. Accuracy and usability of the eGVHD app in assessing the severity of graft-versus-host disease at the 2017 EBMT annual congress. Bone Marrow Transplant. 2018 Apr;53(4):490-494. doi: 10.1038/s41409-017-0017-0. PubMed PMID: 29330389.
Schroeder MC, Rastogi P, Geyer CE Jr, Miller LD, Thomas A. Early and Locally Advanced Metaplastic Breast Cancer: Presentation and Survival by Receptor Status in Surveillance, Epidemiology, and End Results (SEER) 2010-2014. Oncologist. 2018 Apr;23(4):481-488. doi: 10.1634/theoncologist.2017-0398. PubMed PMID: 29330212; PMCID: PMC5896714.
Huyett P, Duvvuri U, Ferris RL, Johnson JT, Schaitkin BM, Kim S. Perineural Invasion in Parotid Gland Malignancies. Otolaryngol Head Neck Surg. 2018 Jun;158(6):1035-1041. doi: 10.1177/0194599817751888. PubMed PMID: 29337642.
Churg A, Hwang H, Tan L, Qing G, Taher A, Tong A, Bilawich AM, Dacic S. Malignant mesothelioma in situ. Histopathology. 2018 May;72(6):1033-1038. doi: 10.1111/his.13468. PubMed PMID: 29350783.
Mazharuddin S, Chattopadhyay A, Levy MY, Redner RL. IRF2BP2-RARA t(1;17)(q42.3;q21.2) APL blasts differentiate in response to all-trans retinoic acid. Leuk Lymphoma. 2018 Sep;59(9):2246-2249. doi: 10.1080/10428194.2017.1421761. PubMed PMID: 29350080; PMCID: PMC6162987.
Leipnitz G, Mohsen AW, Karunanidhi A, Seminotti B, Roginskaya VY, Markantone DM, Grings M, Mihalik SJ, Wipf P, Van Houten B, Vockley J. Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency. Sci Rep. 2018 Jan 18;8(1):1165. doi: 10.1038/s41598-018-19543-3. PubMed PMID: 29348607; PMCID: PMC5773529.
Brufsky AM, Dickler MN. Estrogen Receptor-Positive Breast Cancer: Exploiting Signaling Pathways Implicated in Endocrine Resistance. Oncologist. 2018 May;23(5):528-539. doi: 10.1634/theoncologist.2017-0423. PubMed PMID: 29352052; PMCID: PMC5947450.
Choi YJ, Zhou D, Barbosa ACS, Niu Y, Guan X, Xu M, Ren S, Nolin TD, Liu Y, Xie W. Activation of Constitutive Androstane Receptor Ameliorates Renal Ischemia-Reperfusion-Induced Kidney and Liver Injury. Mol Pharmacol. 2018 Mar;93(3):239-250. doi: 10.1124/mol.117.111146. PubMed PMID: 29351922; PMCID: PMC5801556.
Lindeman NI, Cagle PT, Aisner DL, Arcila ME, Beasley MB, Bernicker EH, Colasacco C, Dacic S, Hirsch FR, Kerr K, Kwiatkowski DJ, Ladanyi M, Nowak JA, Sholl L, Temple-Smolkin R, Solomon B, Souter LH, Thunnissen E, Tsao MS, Ventura CB, Wynes MW, Yatabe Y. Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology. Arch Pathol Lab Med. 2018 Mar;142(3):321-346. doi: 10.5858/arpa.2017-0388-CP. PubMed PMID: 29355391.
Liang S, Johansson E, Barila G, Altschuler DL, Fagman H, Nilsson M. A branching morphogenesis program governs embryonic growth of the thyroid gland. Development. 2018 Jan 25;145(2): doi: 10.1242/dev.146829. PubMed PMID: 29361553; PMCID: PMC5825846.
Dudley B, Karloski E, Monzon FA, Singhi AD, Lincoln SE, Bahary N, Brand RE. Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy. Cancer. 2018 Apr 15;124(8):1691-1700. doi: 10.1002/cncr.31242. PubMed PMID: 29360161.
Koshkin VS, Barata PC, Zhang T, George DJ, Atkins MB, Kelly WJ, Vogelzang NJ, Pal SK, Hsu J, Appleman LJ, Ornstein MC, Gilligan T, Grivas P, Garcia JA, Rini BI. Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma. J Immunother Cancer. 2018 Jan 29;6(1):9. doi: 10.1186/s40425-018-0319-9. PubMed PMID: 29378660; PMCID: PMC5789686.
Bi Y, Shi X, Zhu J, Guan X, Garbacz WG, Huang Y, Gao L, Yan J, Xu M, Ren S, Ren S, Liu Y, Ma X, Li S, Xie W. Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis. Mol Cell Biol. 2018 Apr 1;38(7): doi: 10.1128/MCB.00654-17. PubMed PMID: 29378829; PMCID: PMC5854833.
Wei L, Leibowitz BJ, Epperly M, Bi C, Li A, Steinman J, Wipf P, Li S, Zhang L, Greenberger J, Yu J. The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice. Sci Rep. 2018 Feb 1;8(1):2072. doi: 10.1038/s41598-018-20370-9. PubMed PMID: 29391546; PMCID: PMC5794877.
Belfer I, Pollock NI, Martin JL, Lim KG, De La Cruz C, Van Londen G, Nunziato-Virga SR, Stranieri K, Brufsky AM, Wang H. Effect of gastroretentive gabapentin (Gralise) on postmastectomy pain syndrome: a proof-of-principle open-label study. Pain Rep. 2017 May;2(3):e596. doi: 10.1097/PR9.0000000000000596. PubMed PMID: 29392212; PMCID: PMC5741302.
Gebhardt BJ, Vargo JA, Ling D, Jones B, Mohney M, Clump DA, Ohr JP, Ferris RL, Heron DE. Carotid Dosimetry and the Risk of Carotid Blowout Syndrome After Reirradiation With Head and Neck Stereotactic Body Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 May 1;101(1):195-200. doi: 10.1016/j.ijrobp.2017.11.045. PubMed PMID: 29398127.
Lindeman NI, Cagle PT, Aisner DL, Arcila ME, Beasley MB, Bernicker EH, Colasacco C, Dacic S, Hirsch FR, Kerr K, Kwiatkowski DJ, Ladanyi M, Nowak JA, Sholl L, Temple-Smolkin R, Solomon B, Souter LH, Thunnissen E, Tsao MS, Ventura CB, Wynes MW, Yatabe Y. Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology. J Mol Diagn. 2018 Mar;20(2):129-159. doi: 10.1016/j.jmoldx.2017.11.004. PubMed PMID: 29398453.
Lindeman NI, Cagle PT, Aisner DL, Arcila ME, Beasley MB, Bernicker EH, Colasacco C, Dacic S, Hirsch FR, Kerr K, Kwiatkowski DJ, Ladanyi M, Nowak JA, Sholl L, Temple-Smolkin R, Solomon B, Souter LH, Thunnissen E, Tsao MS, Ventura CB, Wynes MW, Yatabe Y. Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology. J Thorac Oncol. 2018 Mar;13(3):323-358. doi: 10.1016/j.jtho.2017.12.001. PubMed PMID: 29396253.
Caudell JJ, Ward MC, Riaz N, Zakem SJ, Awan MJ, Dunlap NE, Isrow D, Hassanzadeh C, Vargo JA, Heron DE, Marcrom S, Boggs DH, Reddy CA, Dault J, Bonner JA, Higgins KA, Beitler JJ, Koyfman SA, Machtay M, Yao M, Trotti AM, Siddiqui F, Lee NY, Multi-Institution Reirradiation (MIRI) Collaborative.. Volume, Dose, and Fractionation Considerations for IMRT-based Reirradiation in Head and Neck Cancer: A Multi-institution Analysis. Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):606-617. doi: 10.1016/j.ijrobp.2017.11.036. PubMed PMID: 29413274.
Kim YC, Seok S, Byun S, Kong B, Zhang Y, Guo G, Xie W, Ma J, Kemper B, Kemper JK. AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nat Commun. 2018 Feb 7;9(1):540. doi: 10.1038/s41467-018-03060-y. PubMed PMID: 29416063; PMCID: PMC5803255.
Benoist GE, van der Meulen E, van Oort IM, Beumer JH, Somford DM, Schalken JA, Burger DM, van Erp NP. Development and Validation of a Bioanalytical Method to Quantitate Enzalutamide and its Active Metabolite N-Desmethylenzalutamide in Human Plasma: Application to Clinical Management of Patients With Metastatic Castration-Resistant Prostate Cancer. Ther Drug Monit. 2018 Apr;40(2):222-229. doi: 10.1097/FTD.0000000000000484. PubMed PMID: 29419723; PMCID: PMC6085835.
Dohopolski MJ, Horne ZD, Gebhardt BJ, Glaser SM, Edwards RP, Kelley JL, Comerci JT, Olawaiye AB, Courtney-Brooks M, Berger JL, Sukumvanich P, Beriwal S. Single-institutional outcomes of adjuvant brachytherapy for Stage I endometrial cancer-Are outcomes consistent with randomized studies? Brachytherapy. 2018 May - Jun;17(3):564-570. doi: 10.1016/j.brachy.2018.01.004. PubMed PMID: 29426745.
Lee DM, Duensing A. What's the FOX Got to Do with the KITten? Regulating the Lineage-Specific Transcriptional Landscape in GIST. Cancer Discov. 2018 Feb;8(2):146-149. doi: 10.1158/2159-8290.CD-17-1370. PubMed PMID: 29431674.
Leibowitz BJ, Yang L, Wei L, Buchanan ME, Rachid M, Parise RA, Beumer JH, Eiseman JL, Schoen RE, Zhang L, Yu J. Targeting p53-dependent stem cell loss for intestinal chemoprotection. Sci Transl Med. 2018 Feb 7;10(427): doi: 10.1126/scitranslmed.aam7610. PubMed PMID: 29437148; PMCID: PMC5827930.
Brand TM, Hartmann S, Bhola NE, Li H, Zeng Y, O'Keefe RA, Ranall MV, Bandyopadhyay S, Soucheray M, Krogan NJ, Kemp C, Duvvuri U, LaVallee T, Johnson DE, Ozbun MA, Bauman JE, Grandis JR. Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer. Cancer Res. 2018 May 1;78(9):2383-2395. doi: 10.1158/0008-5472.CAN-17-1672. PubMed PMID: 29440171; PMCID: PMC6537867.
Wapnir IL, Price KN, Anderson SJ, Robidoux A, Martín M, Nortier JWR, Paterson AHG, Rimawi MF, Láng I, Baena-Cañada JM, Thürlimann B, Mamounas EP, Geyer CE Jr, Gelber S, Coates AS, Gelber RD, Rastogi P, Regan MM, Wolmark N, Aebi S, International Breast Cancer Study Group., NRG Oncology, GEICAM Spanish Breast Cancer Group, BOOG Dutch Breast Cancer Trialists' Group., Breast International Group.. Efficacy of Chemotherapy for ER-Negative and ER-Positive Isolated Locoregional Recurrence of Breast Cancer: Final Analysis of the CALOR Trial. J Clin Oncol. 2018 Apr 10;36(11):1073-1079. doi: 10.1200/JCO.2017.76.5719. PubMed PMID: 29443653; PMCID: PMC5891132.
Liu H, Liu H, Zhou Z, Parise RA, Chu E, Schmitz JC. Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway. Cell Commun Signal. 2018 Feb 20;16(1):7. doi: 10.1186/s12964-018-0218-1. PubMed PMID: 29458395; PMCID: PMC5819251.
Blumenthal DT, Won M, Mehta MP, Gilbert MR, Brown PD, Bokstein F, Brachman DG, Werner-Wasik M, Hunter GK, Valeinis E, Hopkins K, Souhami L, Howard SP, Lieberman FS, Shrieve DC, Wendland MM, Robinson CG, Zhang P, Corn BW. Short delay in initiation of radiotherapy for patients with glioblastoma-effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group database. Neuro Oncol. 2018 Jun 18;20(7):966-974. doi: 10.1093/neuonc/noy017. PubMed PMID: 29462493; PMCID: PMC6007748.
Hay CM, Kelley JL 3rd, Edwards RP, Pombier KM, Comerci JT Jr. Super-Utilization of Health Care Resources Among Gynecologic Oncology Patients. Am J Med Qual. 2018 Sep/Oct;33(5):509-513. doi: 10.1177/1062860618757343. PubMed PMID: 29463092.
Ma J, Salamoun J, Wipf P, Edwards R, Van Houten B, Qian W. Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential. Oncotarget. 2018 Jan 19;9(5):6042-6054. doi: 10.18632/oncotarget.23679. PubMed PMID: 29464053; PMCID: PMC5814193.
Oesterreich S, Lucas PC, McAuliffe PF, Bruno TC, Vignali DAA. Opening the Door for Immune Oncology Studies in Invasive Lobular Breast Cancer. J Natl Cancer Inst. 2018 Jul 1;110(7):696-698. doi: 10.1093/jnci/djy014. PubMed PMID: 29471462.
Gough A, Shun TY, Taylor DL, Schurdak M. Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies. Methods Mol Biol. 2018;174525-46. doi: 10.1007/978-1-4939-7680-5_2. PubMed PMID: 29476461.
Clark BZ, Farrugia DJ, Landmann A, Diego EJ, Dabbs DJ, Puhalla SL, Jankowitz RC, Brufsky AM, Ahrendt GM, McAuliffe PF, Bhargava R. Prognostic Significance of Modified Residual Disease in Breast and Nodes (mRDBN) Algorithm After Neoadjuvant Chemotherapy for Breast Cancer. Am J Clin Pathol. 2018 Mar 7;149(4):332-343. doi: 10.1093/ajcp/aqx168. PubMed PMID: 29481634.
Vargo JA, Moiseenko V, Grimm J, Caudell J, Clump DA, Yorke E, Xue J, Vinogradskiy Y, Moros EG, Mavroidis P, Jain S, El Naqa I, Marks LB, Heron DE. Head and Neck Tumor Control Probability: Radiation Dose-Volume Effects in Stereotactic Body Radiation Therapy for Locally Recurrent Previously-Irradiated Head and Neck Cancer: Report of the AAPM Working Group. Int J Radiat Oncol Biol Phys. 2018 Jan 31; doi: 10.1016/j.ijrobp.2018.01.044. PubMed PMID: 29477291.
Nicholson AG, Tsao MS, Travis WD, Patil DT, Galateau-Salle F, Marino M, Dacic S, Beasley MB, Butnor KJ, Yatabe Y, Pass HI, Rusch VW, Detterbeck FC, Asamura H, Rice TW, Rami-Porta R. Eighth Edition Staging of Thoracic Malignancies: Implications for the Reporting Pathologist. Arch Pathol Lab Med. 2018 May;142(5):645-661. doi: 10.5858/arpa.2017-0245-RA. PubMed PMID: 29480761.
Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology. 2018 Jun;154(8):2060-2063.e8. doi: 10.1053/j.gastro.2018.02.026. PubMed PMID: 29486199; PMCID: PMC5985217.
Mehrad M, Roy S, LaFramboise WA, Petrosko P, Miller C, Incharoen P, Dacic S. KRAS mutation is predictive of outcome in patients with pulmonary sarcomatoid carcinoma. Histopathology. 2018 Aug;73(2):207-214. doi: 10.1111/his.13505. PubMed PMID: 29489023.
McQueeney KE, Salamoun JM, Burnett JC, Barabutis N, Pekic P, Lewandowski SL, Llaneza DC, Cornelison R, Bai Y, Zhang ZY, Catravas JD, Landen CN, Wipf P, Lazo JS, Sharlow ER. Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor. Oncotarget. 2018 Feb 2;9(9):8223-8240. doi: 10.18632/oncotarget.23787. PubMed PMID: 29492190; PMCID: PMC5823565.
Keating SM, Taylor DL, Plant AL, Litwack ED, Kuhn P, Greenspan EJ, Hartshorn CM, Sigman CC, Kelloff GJ, Chang DD, Friberg G, Lee JSH, Kuida K. Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation. Clin Transl Sci. 2018 May;11(3):267-276. doi: 10.1111/cts.12536. PubMed PMID: 29498218; PMCID: PMC5944591.
Porter TR, Mulvagh SL, Abdelmoneim SS, Becher H, Belcik JT, Bierig M, Choy J, Gaibazzi N, Gillam LD, Janardhanan R, Kutty S, Leong-Poi H, Lindner JR, Main ML, Mathias W Jr, Park MM, Senior R, Villanueva F. Clinical Applications of Ultrasonic Enhancing Agents in Echocardiography: 2018 American Society of Echocardiography Guidelines Update. J Am Soc Echocardiogr. 2018 Mar;31(3):241-274. doi: 10.1016/j.echo.2017.11.013. PubMed PMID: 29502588.
Kalash R, Pifer PM, Beriwal S, Glaser SM, Vargo JA, Heron DE. Exceptional Eight-year Response to Stereotactic Radiosurgery Monotherapy for Multiple Brain Metastases. Cureus. 2017 Dec 29;9(12):e2001. doi: 10.7759/cureus.2001. PubMed PMID: 29507849; PMCID: PMC5832406.
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT. N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2716-E2724. doi: 10.1073/pnas.1719110115. PubMed PMID: 29507222; PMCID: PMC5866579.
Kawamoto T, Oritani K, Curran DP, Kamimura A. Thiol-Catalyzed Radical Decyanation of Aliphatic Nitriles with Sodium Borohydride. Org Lett. 2018 Apr 6;20(7):2084-2087. doi: 10.1021/acs.orglett.8b00626. PubMed PMID: 29517914.
El-Khoueiry AB, O'Donnell R, Semrad TJ, Mack P, Blanchard S, Bahary N, Jiang Y, Yen Y, Wright J, Chen H, Lenz HJ, Gandara DR. A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma. Cancer Chemother Pharmacol. 2018 May;81(5):957-963. doi: 10.1007/s00280-018-3553-4. PubMed PMID: 29520435; PMCID: PMC6330274.
Sadahiro H, Kang KD, Gibson JT, Minata M, Yu H, Shi J, Chhipa R, Chen Z, Lu S, Simoni Y, Furuta T, Sabit H, Zhang S, Bastola S, Yamaguchi S, Alsheikh H, Komarova S, Wang J, Kim SH, Hambardzumyan D, Lu X, Newell EW, DasGupta B, Nakada M, Lee LJ, Nabors B, Norian LA, Nakano I. Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma. Cancer Res. 2018 Jun 1;78(11):3002-3013. doi: 10.1158/0008-5472.CAN-17-2433. PubMed PMID: 29531161; PMCID: PMC5984695.
Kim H, Vargo JA, Beriwal S, Clump DA, Ohr JP, Ferris RL, Heron DE, Huq MS, Smith KJ. Cost-effectiveness analysis of salvage therapies in locoregional previously irradiated head and neck cancer. Head Neck. 2018 Aug;40(8):1743-1751. doi: 10.1002/hed.25142. PubMed PMID: 29537684.
Singh KB, Hahm ER, Rigatti LH, Normolle DP, Yuan JM, Singh SV. Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate. Cancer Prev Res (Phila). 2018 Jun;11(6):337-346. doi: 10.1158/1940-6207.CAPR-17-0389. PubMed PMID: 29545400; PMCID: PMC5984685.
Chen KS, Glaser SM, Garda AE, Vargo JA, Saiful Huq M, Heron DE, Beriwal S. Utilizing clinical pathways and web-based conferences to improve quality of care in a large integrated network using breast cancer radiation therapy as the model. Radiat Oncol. 2018 Mar 16;13(1):44. doi: 10.1186/s13014-018-0995-0. PubMed PMID: 29548340; PMCID: PMC5857077.
Sutera P, Bernard ME, Wang H, Bahary N, Burton S, Zeh H, Heron DE. Stereotactic Body Radiation Therapy for Locally Progressive and Recurrent Pancreatic Cancer after Prior Radiation. Front Oncol. 2018;852. doi: 10.3389/fonc.2018.00052. PubMed PMID: 29564223; PMCID: PMC5845878.
Willis J, Epperly MW, Fisher R, Zhang X, Shields D, Hou W, Wang H, Li S, Wipf P, Parmar K, Guinan E, Steinman J, Greenberger JS. Amelioration of Head and Neck Radiation-Induced Mucositis and Distant Marrow Suppression in Fanca-/- and Fancg-/- Mice by Intraoral Administration of GS-Nitroxide (JP4-039). Radiat Res. 2018 Jun;189(6):560-578. doi: 10.1667/RR14878.1. PubMed PMID: 29584588; PMCID: PMC5973476.
Duvvuri U, Johnson JT, Chiosea SI. Standardized Margin Assessment Is Needed Before Implementing Negative Margin as a Quality Measure. JAMA Otolaryngol Head Neck Surg. 2018 Jun 1;144(6):541-542. doi: 10.1001/jamaoto.2018.0074. PubMed PMID: 29596555.
Jing Y, Bian Y, Hu Z, Wang L, Xie XQ. Deep Learning for Drug Design: an Artificial Intelligence Paradigm for Drug Discovery in the Big Data Era. AAPS J. 2018 Mar 30;20(3):58. doi: 10.1208/s12248-018-0210-0. PubMed PMID: 29603063.
Redner RL, Beumer JH, Kropf P, Agha M, Boyiadzis M, Dorritie K, Farah R, Hou JZ, Im A, Lim SH, Raptis A, Sehgal A, Christner SM, Normolle D, Johnson DE. A phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia. Leuk Lymphoma. 2018 Nov;59(11):2595-2601. doi: 10.1080/10428194.2018.1443330. PubMed PMID: 29616864; PMCID: PMC6201295.
Zhang X, Cao S, Barila G, Edreira MM, Hong K, Wankhede M, Naim N, Buck M, Altschuler DL. Cyclase-associated protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase. J Biol Chem. 2018 May 18;293(20):7659-7673. doi: 10.1074/jbc.RA118.001779. PubMed PMID: 29618512; PMCID: PMC5961064.
Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, Jia L, Li S, Cancer Genome Atlas Research Network., Xie W, Yang D. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell. 2018 Apr 9;33(4):706-720.e9. doi: 10.1016/j.ccell.2018.03.006. PubMed PMID: 29622465; PMCID: PMC6143179.
Polyzos AA, Wood NI, Williams P, Wipf P, Morton AJ, McMurray CT. XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent. PLoS One. 2018;13(4):e0194580. doi: 10.1371/journal.pone.0194580. PubMed PMID: 29630611; PMCID: PMC5890981.
Grilley-Olson JE, Weiss J, Ivanova A, Villaruz LC, Moore DT, Stinchcombe TE, Lee C, Shan JS, Socinski MA. Phase Ib Study of Bavituximab With Carboplatin and Pemetrexed in Chemotherapy-Naive Advanced Nonsquamous Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2018 Jul;19(4):e481-e487. doi: 10.1016/j.cllc.2018.03.008. PubMed PMID: 29631965.
Bian Y, Xie XS. Computational Fragment-Based Drug Design: Current Trends, Strategies, and Applications. AAPS J. 2018 Apr 9;20(3):59. doi: 10.1208/s12248-018-0216-7. PubMed PMID: 29633051.
Dohopolski MJ, Horne Z, Clump D, Burton SA, Heron DE. Stereotactic Body Radiation Therapy for Pulmonary Oligometastases Arising from Non-lung Primaries in Patients Without Extrapulmonary Disease. Cureus. 2018 Feb 7;10(2):e2167. doi: 10.7759/cureus.2167. PubMed PMID: 29644155; PMCID: PMC5889151.
Prabhu AV, Randhawa S, Clump D, Heron DE, Beriwal S. What Do Patients Think About Their Radiation Oncologists? An Assessment of Online Patient Reviews on Healthgrades. Cureus. 2018 Feb 6;10(2):e2165. doi: 10.7759/cureus.2165. PubMed PMID: 29644154; PMCID: PMC5889152.
Ellingson BM, Aftab DT, Schwab GM, Hessel C, Harris RJ, Woodworth DC, Leu K, Chakhoyan A, Raymond C, Drappatz J, de Groot J, Prados MD, Reardon DA, Schiff D, Chamberlain M, Mikkelsen T, Desjardins A, Holland J, Ping J, Weitzman R, Wen PY, Cloughesy TF. Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma. Neuro Oncol. 2018 Sep 3;20(10):1411-1418. doi: 10.1093/neuonc/noy054. PubMed PMID: 29660005; PMCID: PMC6120362.
Cramer JD, Reddy A, Ferris RL, Duvvuri U, Samant S. Comparison of the seventh and eighth edition american joint committee on cancer oral cavity staging systems. Laryngoscope. 2018 Oct;128(10):2351-2360. doi: 10.1002/lary.27205. PubMed PMID: 29658104.
Kornblum N, Zhao F, Manola J, Klein P, Ramaswamy B, Brufsky A, Stella PJ, Burnette B, Telli M, Makower DF, Cheema P, Truica CI, Wolff AC, Soori GS, Haley B, Wassenaar TR, Goldstein LJ, Miller KD, Sparano JA. Randomized Phase II Trial of Fulvestrant Plus Everolimus or Placebo in Postmenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer Resistant to Aromatase Inhibitor Therapy: Results of PrE0102. J Clin Oncol. 2018 Jun 1;36(16):1556-1563. doi: 10.1200/JCO.2017.76.9331. PubMed PMID: 29664714.
Caldwell RM, Bermudez JG, Thai D, Aonbangkhen C, Schuster BS, Courtney T, Deiters A, Hammer DA, Chenoweth DM, Good MC. Optochemical Control of Protein Localization and Activity within Cell-like Compartments. Biochemistry. 2018 May 8;57(18):2590-2596. doi: 10.1021/acs.biochem.8b00131. PubMed PMID: 29671583.
Kong B, Sun R, Huang M, Chow MD, Zhong XB, Xie W, Lee YH, Guo GL. Fibroblast Growth Factor 15-Dependent and Bile Acid-Independent Promotion of Liver Regeneration in Mice. Hepatology. 2018 Nov;68(5):1961-1976. doi: 10.1002/hep.30041. PubMed PMID: 29672888; PMCID: PMC6195490.
Ling DC, Flickinger JC, Burton SA, Heron DE, Quinn AE, Bejjani GK, Engh JA, Gerszten PC, Amankulor NM, Vargo JA. Long-Term Outcomes After Stereotactic Radiosurgery for Spine Metastases: Radiation Dose-Response for Late Toxicity. Int J Radiat Oncol Biol Phys. 2018 Jul 1;101(3):602-609. doi: 10.1016/j.ijrobp.2018.02.035. PubMed PMID: 29678526.
Bender CM, Merriman JD, Sereika SM, Gentry AL, Casillo FE, Koleck TA, Rosenzweig MQ, Brufsky AM, McAuliffe P, Zhu Y, Conley YP. Trajectories of Cognitive Function and Associated Phenotypic and Genotypic Factors in Breast Cancer. Oncol Nurs Forum. 2018 May 1;45(3):308-326. doi: 10.1188/18.ONF.308-326. PubMed PMID: 29683114; PMCID: PMC6052441.
Dorchak JA, Maria S, Guarinoni JL, Duensing A, Somiari S, Cavanaugh J, Deyarmin B, Hu H, Iida J, Shriver CD, Witt-Enderby PA. The Impact of Hormonal Contraceptives on Breast Cancer Pathology. Horm Cancer. 2018 Aug;9(4):240-253. doi: 10.1007/s12672-018-0332-y. PubMed PMID: 29687205.
Tahata S, Singh SV, Lin Y, Hahm ER, Beumer JH, Christner SM, Rao UN, Sander C, Tarhini AA, Tawbi H, Ferris LK, Wilson M, Rose A, Dietz CM, Hughes E, Fahey JW, Leachman SA, Cassidy PB, Butterfield LH, Zarour HM, Kirkwood JM. Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi. Cancer Prev Res (Phila). 2018 Jul;11(7):429-438. doi: 10.1158/1940-6207.CAPR-17-0268. PubMed PMID: 29691233; PMCID: PMC6030491.
Brown W, Liu J, Tsang M, Deiters A. Cell-Lineage Tracing in Zebrafish Embryos with an Expanded Genetic Code. Chembiochem. 2018 Jun 18;19(12):1244-1249. doi: 10.1002/cbic.201800040. PubMed PMID: 29701891; PMCID: PMC6021189.
Hogle BC, Guan X, Folan MM, Xie W. PXR as a mediator of herb-drug interaction. J Food Drug Anal. 2018 Apr;26(2S):S26-S31. doi: 10.1016/j.jfda.2017.11.007. PubMed PMID: 29703383.
Jayasekera J, Li Y, Schechter CB, Jagsi R, Song J, White J, Luta G, Chapman JW, Feuer EJ, Zellars RC, Stout N, Julian TB, Whelan T, Huang X, Shelley Hwang E, Hopkins JO, Sparano JA, Anderson SJ, Fyles AW, Gray R, Sauerbrei W, Mandelblatt J, Berry DA, CISNET-BOLD Collaborative Group .. Simulation Modeling of Cancer Clinical Trials: Application to Omitting Radiotherapy in Low-risk Breast Cancer. J Natl Cancer Inst. 2018 Dec 1;110(12):1360-1369. doi: 10.1093/jnci/djy059. PubMed PMID: 29718314; PMCID: PMC6292816.
Horne ZD, Dohopolski MJ, Clump DA, Burton SA, Heron DE. Thoracic reirradiation with SBRT for residual/recurrent and new primary NSCLC within or immediately adjacent to a prior high-dose radiation field. Pract Radiat Oncol. 2018 May - Jun;8(3):e117-e123. doi: 10.1016/j.prro.2017.11.011. PubMed PMID: 29724402.
Schurdak ME, Pei F, Lezon TR, Carlisle D, Friedlander R, Taylor DL, Stern AM. A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes. Methods Mol Biol. 2018;1787207-222. doi: 10.1007/978-1-4939-7847-2_16. PubMed PMID: 29736721.
Landmann A, Farrugia DJ, Zhu L, Diego EJ, Johnson RR, Soran A, Dabbs DJ, Clark BZ, Puhalla SL, Jankowitz RC, Brufsky AM, Ahrendt GM, McAuliffe PF, Bhargava R. Low Estrogen Receptor (ER)-Positive Breast Cancer and Neoadjuvant Systemic Chemotherapy: Is Response Similar to Typical ER-Positive or ER-Negative Disease? Am J Clin Pathol. 2018 May 31;150(1):34-42. doi: 10.1093/ajcp/aqy028. PubMed PMID: 29741562.
Yang X, Xia R, Yue C, Zhai W, Du W, Yang Q, Cao H, Chen X, Obando D, Zhu Y, Chen X, Chen JJ, Piganelli J, Wipf P, Jiang Y, Xiao G, Wu C, Jiang J, Lu B. ATF4 Regulates CD4+ T Cell Immune Responses through Metabolic Reprogramming. Cell Rep. 2018 May 8;23(6):1754-1766. doi: 10.1016/j.celrep.2018.04.032. PubMed PMID: 29742431; PMCID: PMC6051420.
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ. Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biol. 2018 Jul;17259-273. doi: 10.1016/j.redox.2018.04.007. PubMed PMID: 29747066; PMCID: PMC6006678.
McQueeney KE, Salamoun JM, Ahn JG, Pekic P, Blanco IK, Struckman HL, Sharlow ER, Wipf P, Lazo JS. A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion. FASEB J. 2018 Oct;32(10):5661-5673. doi: 10.1096/fj.201701446R. PubMed PMID: 29746167; PMCID: PMC6133700.
Warsow G, Hübschmann D, Kleinheinz K, Nientiedt C, Heller M, Van Coile L, Tolstov Y, Trennheuser L, Wieczorek K, Pecqueux C, Gasch C, Kuru T, Nyarangi-Dix J, Hatiboglu G, Teber D, Perner S, Stenzinger A, Roth W, Hadaschik B, Pahernik S, Jäger D, Grüllich C, Duensing A, Eils R, Schlesner M, Sültmann H, Hohenfellner M, Duensing S. Genomic features of renal cell carcinoma with venous tumor thrombus. Sci Rep. 2018 May 10;8(1):7477. doi: 10.1038/s41598-018-25544-z. PubMed PMID: 29748622; PMCID: PMC5945671.
Boyiadzis MM, Kirkwood JM, Marshall JL, Pritchard CC, Azad NS, Gulley JL. Significance and implications of FDA approval of pembrolizumab for biomarker-defined disease. J Immunother Cancer. 2018 May 14;6(1):35. doi: 10.1186/s40425-018-0342-x. PubMed PMID: 29754585; PMCID: PMC5950135.
Albergotti WG, Abberbock S, Mathews F, Ferris RL, Johnson JT, Duvvuri U, Kim S. Oligometastatic status as predictor of survival in metastatic human papillomavirus-positive oropharyngeal carcinoma. Head Neck. 2018 Aug;40(8):1685-1690. doi: 10.1002/hed.25171. PubMed PMID: 29756301.
Evers R, Piquette-Miller M, Polli JW, Russel FGM, Sprowl JA, Tohyama K, Ware JA, de Wildt SN, Xie W, Brouwer KLR, International Transporter Consortium.. Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium. Clin Pharmacol Ther. 2018 Nov;104(5):900-915. doi: 10.1002/cpt.1115. PubMed PMID: 29756222; PMCID: PMC6424581.
Dhir M, Zenati MS, Hamad A, Singhi AD, Bahary N, Hogg ME, Zeh HJ 3rd, Zureikat AH. FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel for Neoadjuvant Treatment of Resectable and Borderline Resectable Pancreatic Head Adenocarcinoma. Ann Surg Oncol. 2018 Jul;25(7):1896-1903. doi: 10.1245/s10434-018-6512-8. PubMed PMID: 29761331.
Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, Kubo M, Wang L, Wolmark N, Weinshilboum RM. Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Pharmacogenet Genomics. 2018 Jun;28(6):147-152. doi: 10.1097/FPC.0000000000000337. PubMed PMID: 29768301; PMCID: PMC5965682.
Liu YW, Li S, Dai SS. Neutrophils in traumatic brain injury (TBI): friend or foe? J Neuroinflammation. 2018 May 17;15(1):146. doi: 10.1186/s12974-018-1173-x. PubMed PMID: 29776443; PMCID: PMC5960133.
Mantica M, Pritchard A, Lieberman F, Drappatz J. Retrospective study of nivolumab for patients with recurrent high grade gliomas. J Neurooncol. 2018 Sep;139(3):625-631. doi: 10.1007/s11060-018-2907-4. PubMed PMID: 29779086.
Rieser CJ, Zenati M, Hamad A, Al Abbas AI, Bahary N, Zureikat AH, Zeh HJ 3rd, Hogg ME. CA19-9 on Postoperative Surveillance in Pancreatic Ductal Adenocarcinoma: Predicting Recurrence and Changing Prognosis over Time. Ann Surg Oncol. 2018 Nov;25(12):3483-3491. doi: 10.1245/s10434-018-6521-7. PubMed PMID: 29786131.
Kalash R, Glaser SM, Flickinger JC, Burton S, Heron DE, Gerszten PC, Engh JA, Amankulor NM, Vargo JA. Stereotactic body radiation therapy for benign spine tumors: is dose de-escalation appropriate? J Neurosurg Spine. 2018 Aug;29(2):220-225. doi: 10.3171/2017.12.SPINE17920. PubMed PMID: 29799334.
Tsao MS, Kerr KM, Kockx M, Beasley MB, Borczuk AC, Botling J, Bubendorf L, Chirieac L, Chen G, Chou TY, Chung JH, Dacic S, Lantuejoul S, Mino-Kenudson M, Moreira AL, Nicholson AG, Noguchi M, Pelosi G, Poleri C, Russell PA, Sauter J, Thunnissen E, Wistuba I, Yu H, Wynes MW, Pintilie M, Yatabe Y, Hirsch FR. PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project. J Thorac Oncol. 2018 Sep;13(9):1302-1311. doi: 10.1016/j.jtho.2018.05.013. PubMed PMID: 29800747.
Ikeda Y, Zabbarova IV, Birder LA, Wipf P, Getchell SE, Tyagi P, Fry CH, Drake MJ, Kanai AJ. Relaxin-2 therapy reverses radiation-induced fibrosis and restores bladder function in mice. Neurourol Urodyn. 2018 Nov;37(8):2441-2451. doi: 10.1002/nau.23721. PubMed PMID: 29806709; PMCID: PMC6202145.
Zabbarova IV, Ikeda Y, Carder EJ, Wipf P, Wolf-Johnston AS, Birder LA, Yoshimura N, Getchell SE, Almansoori K, Tyagi P, Fry CH, Drake MJ, Kanai AJ. Targeting p75 neurotrophin receptors ameliorates spinal cord injury-induced detrusor sphincter dyssynergia in mice. Neurourol Urodyn. 2018 Nov;37(8):2452-2461. doi: 10.1002/nau.23722. PubMed PMID: 29806700; PMCID: PMC6202156.
Boyiadzis M, Whiteside TL. Exosomes in acute myeloid leukemia inhibit hematopoiesis. Curr Opin Hematol. 2018 Jul;25(4):279-284. doi: 10.1097/MOH.0000000000000439. PubMed PMID: 29846239.
Shimoi M, Watanabe T, Maeda K, Curran DP, Taniguchi T. Radical trans-Hydroboration of Alkynes with N-Heterocyclic Carbene Boranes. Angew Chem Int Ed Engl. 2018 Jul 20;57(30):9485-9490. doi: 10.1002/anie.201804515. PubMed PMID: 29845716.
Chu E. How I treat chemorefractory metastatic colorectal cancer. Clin Adv Hematol Oncol. 2018 May;16(5):340-345. PubMed PMID: 29851930.
Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE Jr, Dees EC, Goetz MP, Olson JA Jr, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Ravdin PM, Keane MM, Gomez Moreno HL, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW Jr. Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer. N Engl J Med. 2018 Jul 12;379(2):111-121. doi: 10.1056/NEJMoa1804710. PubMed PMID: 29860917; PMCID: PMC6172658.
Deiters A. Special Issue on Optochemical and Optogenetic Control of Cellular Processes. Chembiochem. 2018 Jun 18;19(12):1198-1200. doi: 10.1002/cbic.201800277. PubMed PMID: 29873157.
Sun J, Sun L, Li J, Xu J, Wan Z, Ouyang Z, Liang L, Li S, Zeng D. A multi-functional polymeric carrier for simultaneous positron emission tomography imaging and combination therapy. Acta Biomater. 2018 Jul 15;75312-322. doi: 10.1016/j.actbio.2018.06.010. PubMed PMID: 29885530; PMCID: PMC6119490.
Pecqueux C, Arslan A, Heller M, Falkenstein M, Kaczorowski A, Tolstov Y, Sültmann H, Grüllich C, Herpel E, Duensing A, Kristiansen G, Hohenfellner M, Navone NM, Duensing S. FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer. Urol Oncol. 2018 Aug;36(8):365.e15-365.e26. doi: 10.1016/j.urolonc.2018.05.020. PubMed PMID: 29887238.
Özbek U, Lin HM, Lin Y, Weeks DE, Chen W, Shaffer JR, Purcell SM, Feingold E. Statistics for X-chromosome associations. Genet Epidemiol. 2018 Sep;42(6):539-550. doi: 10.1002/gepi.22132. PubMed PMID: 29900581; PMCID: PMC6394852.
Schoemans HM, Goris K, Van Durm R, Fieuws S, De Geest S, Pavletic SZ, Im A, Wolff D, Lee SJ, Greinix H, Duarte RF, Poiré X, Selleslag D, Lewalle P, Kerre T, Graux C, Baron F, Maertens JA, Dobbels F, EBMT Transplantation Complications Working party.. The eGVHD App has the potential to improve the accuracy of graft-versus-host disease assessment: a multicenter randomized controlled trial. Haematologica. 2018 Oct;103(10):1698-1707. doi: 10.3324/haematol.2018.190777. PubMed PMID: 29903762; PMCID: PMC6165809.
Sutera P, Kalash R, Flickinger J, Engh J, Heron DE. Clinical and Molecular Recursive Partitioning Analysis of High-grade Glioma Treated With IMRT. Am J Clin Oncol. 2019 Jan;42(1):27-35. doi: 10.1097/COC.0000000000000470. PubMed PMID: 29912004.
Dabbs DJ, Clark BZ, Serdy K, Onisko A, Brufsky AM, Smalley S, Perkins S, Bhargava R. Pathologist's health-care value in the triage of Oncotype DX® testing: a value-based pathology study of tumour biology with outcomes. Histopathology. 2018 Oct;73(4):692-700. doi: 10.1111/his.13690. PubMed PMID: 29920746.
Beumer JH, Chu E, Allegra C, Tanigawara Y, Milano G, Diasio R, Kim TW, Mathijssen RH, Zhang L, Arnold D, Muneoka K, Boku N, Joerger M. Therapeutic Drug Monitoring in Oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology Recommendations for 5-Fluorouracil Therapy. Clin Pharmacol Ther. 2019 Mar;105(3):598-613. doi: 10.1002/cpt.1124. PubMed PMID: 29923599; PMCID: PMC6309286.
Subervie D, Graff B, Nerkar S, Curran DP, Lalevée J, Lacôte E. Difluorination at Boron Leads to the First Electrophilic Ligated Boryl Radical (NHC-BF2. ). Angew Chem Int Ed Engl. 2018 Aug 6;57(32):10251-10256. doi: 10.1002/anie.201806476. PubMed PMID: 29928777.
Lontos K, Tsagianni A, Yuan JM, Normolle DP, Boyiadzis M, Hou JZ, Swerdlow SH, Dorritie KA. Location matters in early stage nodal diffuse large B-cell lymphoma. Leuk Lymphoma. 2019 Jan;60(1):250-253. doi: 10.1080/10428194.2018.1471600. PubMed PMID: 29932787.
Gebhardt BJ, Vargo JA, Kim H, Houser CJ, Glaser SM, Sukumvanich P, Olawaiye AB, Kelley JL, Edwards RP, Comerci JT, Courtney-Brooks M, Beriwal S. Image-based multichannel vaginal cylinder brachytherapy for the definitive treatment of gynecologic malignancies in the vagina. Gynecol Oncol. 2018 Aug;150(2):293-299. doi: 10.1016/j.ygyno.2018.06.011. PubMed PMID: 29929925.
Lou W, Ting HC, Reynolds CA, Tyurina YY, Tyurin VA, Li Y, Ji J, Yu W, Liang Z, Stoyanovsky DA, Anthonymuthu TS, Frasso MA, Wipf P, Greenberger JS, Bayır H, Kagan VE, Greenberg ML. Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1354-1368. doi: 10.1016/j.bbalip.2018.06.016. PubMed PMID: 29935382.
Jing Y, Bian Y, Hu Z, Wang L, Xie XQ. Correction to: Deep Learning for Drug Design: an Artificial Intelligence Paradigm for Drug Discovery in the Big Data Era. AAPS J. 2018 Jun 25;20(4):79. doi: 10.1208/s12248-018-0243-4. PubMed PMID: 29943256.
Vendetti FP, Karukonda P, Clump DA, Teo T, Lalonde R, Nugent K, Ballew M, Kiesel BF, Beumer JH, Sarkar SN, Conrads TP, O'Connor MJ, Ferris RL, Tran PT, Delgoffe GM, Bakkenist CJ. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. J Clin Invest. 2018 Aug 31;128(9):3926-3940. doi: 10.1172/JCI96519. PubMed PMID: 29952768; PMCID: PMC6118586.
Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS. Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets. J Natl Cancer Inst. 2019 Apr 1;111(4):388-398. doi: 10.1093/jnci/djy110. PubMed PMID: 29961873; PMCID: PMC6449168.
Chao DT, Shah NH, Zeh HJ 3rd, Singhi AD, Bahary N, McGrath KM, Fasanella KE, Zureikat AH, Whitcomb DC, Brand RE. Overweight or Obese Individuals at Eighteen Years of Age Develop Pancreatic Adenocarcinoma at a Significantly Earlier Age. Gastroenterol Res Pract. 2018;20182380596. doi: 10.1155/2018/2380596. PubMed PMID: 29967636; PMCID: PMC6008748.
Saloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM. Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma. Pancreas. 2018 Aug;47(7):856-863. doi: 10.1097/MPA.0000000000001090. PubMed PMID: 29975347; PMCID: PMC6044729.
Retseck J, Nasr A, Lin Y, Lin H, Mendiratta P, Butterfield LH, Tarhini AA. Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma. J Transl Med. 2018 Jul 4;16(1):184. doi: 10.1186/s12967-018-1563-y. PubMed PMID: 29973204; PMCID: PMC6033230.
Heron DE, Suntharalingam N, Winkfield KM, Regine WF. Carl Mansfield, MD, ScD, FACR, FASTRO (1928-2018). Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):765-766. doi: 10.1016/j.ijrobp.2018.03.004. PubMed PMID: 29976486.
Prabhu AV, Karukonda P, Hansberry DR, Heron DE, Thomas CR Jr. A Window to Internet-based Information Seeking of US Fourth-Year Medical Students: Are Radiation Oncology Residency Program Websites Comprehensive? Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):789-791. doi: 10.1016/j.ijrobp.2018.04.005. PubMed PMID: 29976490.
Thakur PC, Miller-Ocuin JL, Nguyen K, Matsuda R, Singhi AD, Zeh HJ, Bahary N. Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer. J Transl Med. 2018 Jul 9;16(1):190. doi: 10.1186/s12967-018-1562-z. PubMed PMID: 29986726; PMCID: PMC6038181.
Naro Y, Ankenbruck N, Thomas M, Tivon Y, Connelly CM, Gardner L, Deiters A. Small Molecule Inhibition of MicroRNA miR-21 Rescues Chemosensitivity of Renal-Cell Carcinoma to Topotecan. J Med Chem. 2018 Jul 26;61(14):5900-5909. doi: 10.1021/acs.jmedchem.7b01891. PubMed PMID: 29993250.
Tramonti A, Paiardini A, Paone A, Bouzidi A, Giardina G, Guiducci G, Magnifico MC, Rinaldo S, McDermott L, Menendez JA, Contestabile R, Cutruzzolà F. Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes. Arch Biochem Biophys. 2018 Sep 1;65371-79. doi: 10.1016/j.abb.2018.07.001. PubMed PMID: 29991441.
Ye J, Das S, Roy A, Wei W, Huang H, Lorenz-Guertin JM, Xu Q, Jacob TC, Wang B, Sun D, Wang QJ. Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway. Mol Neurobiol. 2019 Mar;56(3):2123-2136. doi: 10.1007/s12035-018-1198-2. PubMed PMID: 29992531; PMCID: PMC6394630.
Saydmohammed M, Vollmer LL, Onuoha EO, Maskrey TS, Gibson G, Watkins SC, Wipf P, Vogt A, Tsang M. A High-Content Screen Reveals New Small-Molecule Enhancers of Ras/Mapk Signaling as Probes for Zebrafish Heart Development. Molecules. 2018 Jul 11;23(7): doi: 10.3390/molecules23071691. PubMed PMID: 29997348; PMCID: PMC6099644.
Dai W, Geib SJ, Curran DP. Reactions of N-Heterocyclic Carbene Boranes with 5-Diazo-2,2-dimethyl-1,3-dioxane-4,6-dione: Synthesis of Mono- and Bis-hydrazonyl NHC-Boranes. J Org Chem. 2018 Aug 3;83(15):8775-8779. doi: 10.1021/acs.joc.8b01125. PubMed PMID: 30004702.
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Wang L, Ma S, Hu Z, McGuire TF, Xie XS. Chemogenomics Systems Pharmacology Mapping of Potential Drug Targets for Treatment of Traumatic Brain Injury. J Neurotrauma. 2019 Feb 15;36(4):565-575. doi: 10.1089/neu.2018.5757. PubMed PMID: 30014763; PMCID: PMC6354609.
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Zhu J, Wang P, Li F, Lu J, Shehu AI, Xie W, McMahon D, Ma X. CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitor. Biochem Pharmacol. 2018 Dec;158174-184. doi: 10.1016/j.bcp.2018.10.012. PubMed PMID: 30342022; PMCID: PMC6263788.
Lu P, Cai X, Guo Y, Xu M, Tian J, Locker J, Xie W. Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b. Toxicol Sci. 2019 Feb 1;167(2):581-592. doi: 10.1093/toxsci/kfy263. PubMed PMID: 30346592; PMCID: PMC6358271.
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Li B, Zhu Y, Chen H, Gao H, He H, Zuo N, Pei L, Xie W, Chen L, Ao Y, Wang H. Decreased H3K9ac level of AT2R mediates the developmental origin of glomerulosclerosis induced by prenatal dexamethasone exposure in male offspring rats. Toxicology. 2019 Jan 1;41132-42. doi: 10.1016/j.tox.2018.10.013. PubMed PMID: 30359671.
Bortsov AV, Devor M, Kaunisto MA, Kalso E, Brufsky A, Kehlet H, Aasvang E, Bittner R, Diatchenko L, Belfer I. CACNG2 polymorphisms associate with chronic pain after mastectomy. Pain. 2019 Mar;160(3):561-568. doi: 10.1097/j.pain.0000000000001432. PubMed PMID: 30371558; PMCID: PMC6377334.
Dai W, McFadden TR, Curran DP, Früchtl HA, Walton JC. 5- Endo Cyclizations of NHC-Boraallyl Radicals Bearing Ester Substituents: Characterization of Derived 1,2-Oxaborole Radicals and Boralactones. J Am Chem Soc. 2018 Nov 21;140(46):15868-15875. doi: 10.1021/jacs.8b09288. PubMed PMID: 30369236.
Dressen MS, Muthukrishnan A, Tragon TR, Lieberman FS, Mountz JM. Complementary Molecular and Metabolic Characterization of Meningiomas With DOTATATE and FDG-PET: Advancing Treatment Planning and Prognostication. Clin Nucl Med. 2019 Jan;44(1):e26-e27. doi: 10.1097/RLU.0000000000002328. PubMed PMID: 30371576.
Kansy BA, Shayan G, Jie HB, Gibson SP, Lei YL, Brandau S, Lang S, Schmitt NC, Ding F, Lin Y, Ferris RL. T cell receptor richness in peripheral blood increases after cetuximab therapy and correlates with therapeutic response. Oncoimmunology. 2018;7(11):e1494112. doi: 10.1080/2162402X.2018.1494112. PubMed PMID: 30377562; PMCID: PMC6205044.
Pandey A, Brufsky AM. Metastatic Breast Cancer Patient With Activating HER2 Exon 20 Insertion Mutation With Response to Poziotinib: Case Report of Compassionate Drug Use. Clin Breast Cancer. 2019 Feb;19(1):e7-e11. doi: 10.1016/j.clbc.2018.09.010. PubMed PMID: 30391215.
Heng YJ, Wang J, Ahearn TU, Brown SB, Zhang X, Ambrosone CB, de Andrade VP, Brufsky AM, Couch FJ, King TA, Modugno F, Vachon CM, DuPre NC, Garcia-Closas M, Troester MA, Hunter DJ, Eliassen AH, Tamimi RM, Hankinson SE, Beck AH. Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues. Breast Cancer Res Treat. 2019 Feb;173(3):667-677. doi: 10.1007/s10549-018-5034-1. PubMed PMID: 30387004; PMCID: PMC6391202.
Hu Z, Wang L, Ma S, Kirisci L, Feng Z, Xue Y, Klunk WE, Kamboh MI, Sweet RA, Becker J, Lv Q, Lopez OL, Xie XQ. Synergism of antihypertensives and cholinesterase inhibitors in Alzheimer's disease. Alzheimers Dement (N Y). 2018;4542-555. doi: 10.1016/j.trci.2018.09.001. PubMed PMID: 30386819; PMCID: PMC6205113.
Wu X, Xie S, Wang L, Fan P, Ge S, Xie XQ, Wu W. A computational strategy for finding novel targets and therapeutic compounds for opioid dependence. PLoS One. 2018;13(11):e0207027. doi: 10.1371/journal.pone.0207027. PubMed PMID: 30403753; PMCID: PMC6221321.
Clump DA, Pickering CR, Skinner HD. Predicting Outcome in Head and Neck Cancer: miRNAs with Potentially Big Effects. Clin Cancer Res. 2019 Mar 1;25(5):1441-1442. doi: 10.1158/1078-0432.CCR-18-3078. PubMed PMID: 30413524; PMCID: PMC6415532.
Ofo E, Spiers H, Kim D, Duvvuri U. Transoral Robotic Surgery and the Unknown Primary. ORL J Otorhinolaryngol Relat Spec. 2018;80(3-4):148-155. doi: 10.1159/000490596. PubMed PMID: 30419564.
Hugar LA, Yabes JG, Turner RM 2nd, Fam MM, Appleman LJ, Davies BJ, Jacobs BL. Rate and Determinants of Completing Neoadjuvant Chemotherapy in Medicare Beneficiaries With Bladder Cancer: A SEER-Medicare Analysis. Urology. 2019 Feb;124191-197. doi: 10.1016/j.urology.2018.11.001. PubMed PMID: 30423302.
Kesch C, Radtke JP, Wintsche A, Wiesenfarth M, Luttje M, Gasch C, Dieffenbacher S, Pecqueux C, Teber D, Hatiboglu G, Nyarangi-Dix J, Simpfendörfer T, Schönberg G, Dimitrakopoulou-Strauss A, Freitag M, Duensing A, Grüllich C, Jäger D, Götz M, Grabe N, Schweiger MR, Pahernik S, Perner S, Herpel E, Roth W, Wieczorek K, Maier-Hein K, Debus J, Haberkorn U, Giesel F, Galle J, Hadaschik B, Schlemmer HP, Hohenfellner M, Bonekamp D, Sültmann H, Duensing S. Correlation between genomic index lesions and mpMRI and 68Ga-PSMA-PET/CT imaging features in primary prostate cancer. Sci Rep. 2018 Nov 12;8(1):16708. doi: 10.1038/s41598-018-35058-3. PubMed PMID: 30420756; PMCID: PMC6232089.
LaPorte MG, Burnett JC, Colombo R, Bulfer SL, Alverez C, Chou TF, Neitz RJ, Green N, Moore WJ, Yue Z, Li S, Arkin MR, Wipf P, Huryn DM. Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97. ACS Med Chem Lett. 2018 Nov 8;9(11):1075-1081. doi: 10.1021/acsmedchemlett.8b00372. PubMed PMID: 30429948; PMCID: PMC6231190.
Gadgeel SM, Stevenson JP, Langer CJ, Gandhi L, Borghaei H, Patnaik A, Villaruz LC, Gubens M, Hauke R, Yang JC, Sequist LV, Bachman R, Saraf S, Raftopoulos H, Papadimitrakopoulou V. Pembrolizumab and platinum-based chemotherapy as first-line therapy for advanced non-small-cell lung cancer: Phase 1 cohorts from the KEYNOTE-021 study. Lung Cancer. 2018 Nov;125273-281. doi: 10.1016/j.lungcan.2018.08.019. PubMed PMID: 30429032.
Seminotti B, Leipnitz G, Karunanidhi A, Kochersperger C, Roginskaya VY, Basu S, Wang Y, Wipf P, Van Houten B, Mohsen AW, Vockley J. Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers. Hum Mol Genet. 2019 Mar 15;28(6):928-941. doi: 10.1093/hmg/ddy403. PubMed PMID: 30445591; PMCID: PMC6400046.
Geyer CE Jr, Tang G, Mamounas EP, Rastogi P, Paik S, Shak S, Baehner FL, Crager M, Wickerham DL, Costantino JP, Wolmark N. 21-Gene assay as predictor of chemotherapy benefit in HER2-negative breast cancer. NPJ Breast Cancer. 2018;437. doi: 10.1038/s41523-018-0090-6. PubMed PMID: 30456299; PMCID: PMC6235896.
Singh R, Mehrotra S, Gopalakrishnan M, Gojo I, Karp JE, Greer JM, Chen A, Piekarz R, Kiesel BF, Gobburu J, Rudek MA, Beumer JH, ETCTN-6745 study team.. Population pharmacokinetics and exposure-response assessment of veliparib co-administered with temozolomide in patients with myeloid leukemias. Cancer Chemother Pharmacol. 2019 Feb;83(2):319-328. doi: 10.1007/s00280-018-3731-4. PubMed PMID: 30456480; PMCID: PMC6404524.
Beckwitt CH, Brufsky A, Oltvai ZN, Wells A. Statin drugs to reduce breast cancer recurrence and mortality. Breast Cancer Res. 2018 Nov 20;20(1):144. doi: 10.1186/s13058-018-1066-z. PubMed PMID: 30458856; PMCID: PMC6247616.
Gyanchandani R, Kvam E, Heller R, Finehout E, Smith N, Kota K, Nelson JR, Griffin W, Puhalla S, Brufsky AM, Davidson NE, Lee AV. Whole genome amplification of cell-free DNA enables detection of circulating tumor DNA mutations from fingerstick capillary blood. Sci Rep. 2018 Nov 23;8(1):17313. doi: 10.1038/s41598-018-35470-9. PubMed PMID: 30470782; PMCID: PMC6251935.
Cheikhi A, Wallace C, St Croix C, Cohen C, Tang WY, Wipf P, Benos PV, Ambrosio F, Barchowsky A. Mitochondria are a substrate of cellular memory. Free Radic Biol Med. 2019 Jan;130528-541. doi: 10.1016/j.freeradbiomed.2018.11.028. PubMed PMID: 30472365.
Randhawa S, Viqar A, Strother J, Prabhu AV, Xia F, Heron D, Beriwal S. How Do Patients Rate Their Radiation Oncologists in the Modern Era: An Analysis of Vitals.com. Cureus. 2018 Sep 17;10(9):e3312. doi: 10.7759/cureus.3312. PubMed PMID: 30473945; PMCID: PMC6248776.
Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA. Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells. J Biol Chem. 2019 Jan 11;294(2):397-404. doi: 10.1074/jbc.AC118.005899. PubMed PMID: 30478172; PMCID: PMC6333886.
Lieberman FS, Wang M, Robins HI, Tsien CI, Curran WJ Jr, Werner-Wasik M, Smith RP, Schultz C, Hartford AC, Zhang P, Mehta MP. Phase 2 Study of Radiation Therapy Plus Low-Dose Temozolomide Followed by Temozolomide and Irinotecan for Glioblastoma: NRG Oncology RTOG Trial 0420. Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):878-886. doi: 10.1016/j.ijrobp.2018.11.008. PubMed PMID: 30496882.
Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Structural Basis of Polyketide Synthase O-Methylation. ACS Chem Biol. 2018 Dec 21;13(12):3221-3228. doi: 10.1021/acschembio.8b00687. PubMed PMID: 30489068; PMCID: PMC6470024.
Sivananthan A, Shields D, Fisher R, Hou W, Zhang X, Franicola D, Epperly MW, Wipf P, Greenberger JS. Continuous One Year Oral Administration of the Radiation Mitigator, MMS350, after Total-Body Irradiation, Restores Bone Marrow Stromal Cell Proliferative Capacity and Reduces Senescence in Fanconi Anemia (Fanca-/-) Mice. Radiat Res. 2019 Feb;191(2):139-153. doi: 10.1667/RR15199.1. PubMed PMID: 30499383; PMCID: PMC6388094.
Close DA, Wang AX, Kochanek SJ, Shun T, Eiseman JL, Johnston PA. Implementation of the NCI-60 Human Tumor Cell Line Panel to Screen 2260 Cancer Drug Combinations to Generate >3 Million Data Points Used to Populate a Large Matrix of Anti-Neoplastic Agent Combinations (ALMANAC) Database. SLAS Discov. 2019 Mar;24(3):242-263. doi: 10.1177/2472555218812429. PubMed PMID: 30500310.
Mamounas EP, Bandos H, Lembersky BC, Jeong JH, Geyer CE Jr, Rastogi P, Fehrenbacher L, Graham ML, Chia SK, Brufsky AM, Walshe JM, Soori GS, Dakhil SR, Seay TE, Wade JL 3rd, McCarron EC, Paik S, Swain SM, Wickerham DL, Wolmark N. Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncol. 2019 Jan;20(1):88-99. doi: 10.1016/S1470-2045(18)30621-1. PubMed PMID: 30509771.
Boyiadzis MM, Dhodapkar MV, Brentjens RJ, Kochenderfer JN, Neelapu SS, Maus MV, Porter DL, Maloney DG, Grupp SA, Mackall CL, June CH, Bishop MR. Chimeric antigen receptor (CAR) T therapies for the treatment of hematologic malignancies: clinical perspective and significance. J Immunother Cancer. 2018 Dec 4;6(1):137. doi: 10.1186/s40425-018-0460-5. PubMed PMID: 30514386; PMCID: PMC6278156.
von Minckwitz G, Huang CS, Mano MS, Loibl S, Mamounas EP, Untch M, Wolmark N, Rastogi P, Schneeweiss A, Redondo A, Fischer HH, Jacot W, Conlin AK, Arce-Salinas C, Wapnir IL, Jackisch C, DiGiovanna MP, Fasching PA, Crown JP, Wülfing P, Shao Z, Rota Caremoli E, Wu H, Lam LH, Tesarowski D, Smitt M, Douthwaite H, Singel SM, Geyer CE Jr, KATHERINE Investigators.. Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer. N Engl J Med. 2019 Feb 14;380(7):617-628. doi: 10.1056/NEJMoa1814017. PubMed PMID: 30516102.
Kochanek PM, Jackson TC, Jha RM, Clark RSB, Okonkwo DO, Bayır H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au AK, Elmer J, Treble-Barna A, Ikonomovic MD, Shutter LA, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR, Dixon CE. Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. J Neurotrauma. 2019 Feb 1; doi: 10.1089/neu.2018.6203. PubMed PMID: 30520681.
Xu D, Huang S, Wang H, Xie W. Regulation of brain drug metabolizing enzymes and transporters by nuclear receptors. Drug Metab Rev. 2018 Nov;50(4):407-414. doi: 10.1080/03602532.2018.1554673. PubMed PMID: 30501435.
Cramer JD, Ferris RL, Kim S, Duvvuri U. Primary surgery for human papillomavirus-associated oropharyngeal cancer: Survival outcomes with or without adjuvant treatment. Oral Oncol. 2018 Dec;87170-176. doi: 10.1016/j.oraloncology.2018.10.039. PubMed PMID: 30527235; PMCID: PMC6533632.
Rodríguez-Lopéz JL, Ling DC, Heron DE, Beriwal S. Lag Time Between Evidence and Guidelines: Can Clinical Pathways Bridge the Gap? J Oncol Pract. 2019 Mar;15(3):e195-e201. doi: 10.1200/JOP.18.00430. PubMed PMID: 30526227.
Chan WC, Koide K. Total Synthesis of the Reported Structure of Stresgenin B Enabled by the Diastereoselective Cyanation of an Oxocarbenium. Org Lett. 2018 Dec 21;20(24):7798-7802. doi: 10.1021/acs.orglett.8b03219. PubMed PMID: 30525686.
Chiang AN, Liang M, Dominguez-Meijide A, Masaracchia C, Goeckeler-Fried JL, Mazzone CS, Newhouse DW, Kendsersky NM, Yates ME, Manos-Turvey A, Needham PG, Outeiro TF, Wipf P, Brodsky JL. Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorg Med Chem. 2019 Jan 1;27(1):79-91. doi: 10.1016/j.bmc.2018.11.011. PubMed PMID: 30528127; PMCID: PMC6298824.
Chen L, Liu Q, Tang Q, Kuang J, Li H, Pu S, Wu T, Yang X, Li R, Zhang J, Zhang Z, Huang Y, Li Y, Zou M, Jiang W, Li T, Gong M, Zhang L, Wang H, Qu A, Xie W, He J. Hepatocyte-specific Sirt6 deficiency impairs ketogenesis. J Biol Chem. 2019 Feb 1;294(5):1579-1589. doi: 10.1074/jbc.RA118.005309. PubMed PMID: 30530497; PMCID: PMC6364758.
Duska LR, Petroni GR, Lothamer H, Faust W Jr, Beumer JH, Christner SM, Mills AM, Fracasso PM, Parsons SJ. A window-of-opportunity clinical trial of dasatinib in women with newly diagnosed endometrial cancer. Cancer Chemother Pharmacol. 2019 Mar;83(3):473-482. doi: 10.1007/s00280-018-3749-7. PubMed PMID: 30535536.
Brown JB, Pai RK, Burgess MA, Chennat J, Zureikat AH. Pathologic Complete Response in a Large Gastric GIST: Using Molecular Markers to Achieve Maximal Response to Neoadjuvant Imatinib. J Natl Compr Canc Netw. 2018 Dec;16(12):1424-1428. doi: 10.6004/jnccn.2018.7063. PubMed PMID: 30545989.
Darrah K, Wang T, Cook I, Cacace M, Deiters A, Leyh TS. Allosteres to regulate neurotransmitter sulfonation. J Biol Chem. 2019 Feb 15;294(7):2293-2301. doi: 10.1074/jbc.RA118.006511. PubMed PMID: 30545938; PMCID: PMC6378965.
Guo GL, Xie W. Metformin action through the microbiome and bile acids. Nat Med. 2018 Dec;24(12):1789-1790. doi: 10.1038/s41591-018-0273-6. PubMed PMID: 30523325.
Naim N, White AD, Reece JM, Wankhede M, Zhang X, Vilardaga JP, Altschuler DL. Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis. J Biol Chem. 2019 Jan 25;294(4):1095-1103. doi: 10.1074/jbc.AC118.004905. PubMed PMID: 30559293; PMCID: PMC6349105.
Sun W, Patel A, Normolle D, Patel K, Ohr J, Lee JJ, Bahary N, Chu E, Streeter N, Drummond S. A phase 2 trial of regorafenib as a single agent in patients with chemotherapy-refractory, advanced, and metastatic biliary tract adenocarcinoma. Cancer. 2019 Mar 15;125(6):902-909. doi: 10.1002/cncr.31872. PubMed PMID: 30561756; PMCID: PMC6402964.
Wang J, Ge Y, Xie XQ. Development and Testing of Druglike Screening Libraries. J Chem Inf Model. 2019 Jan 28;59(1):53-65. doi: 10.1021/acs.jcim.8b00537. PubMed PMID: 30563329.
Yatabe Y, Dacic S, Borczuk AC, Warth A, Russell PA, Lantuejoul S, Beasley MB, Thunnissen E, Pelosi G, Rekhtman N, Bubendorf L, Mino-Kenudson M, Yoshida A, Geisinger KR, Noguchi M, Chirieac LR, Bolting J, Chung JH, Chou TY, Chen G, Poleri C, Lopez-Rios F, Papotti M, Sholl LM, Roden AC, Travis WD, Hirsch FR, Kerr KM, Tsao MS, Nicholson AG, Wistuba I, Moreira AL. Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer. J Thorac Oncol. 2019 Mar;14(3):377-407. doi: 10.1016/j.jtho.2018.12.005. PubMed PMID: 30572031; PMCID: PMC6422775.
Strober WA, Sridharan S, Duvvuri U, Cramer JD. Variation in the Quality of Head and Neck Cancer Care in the United States. JAMA Otolaryngol Head Neck Surg. 2018 Dec 20; doi: 10.1001/jamaoto.2018.3632. PubMed PMID: 30570653; PMCID: PMC6439588.
Qin Q, Xie Y, Floreancig PE. Diarylmethane synthesis through Re2O7-catalyzed bimolecular dehydrative Friedel-Crafts reactions. Chem Sci. 2018 Dec 7;9(45):8528-8534. doi: 10.1039/c8sc03570a. PubMed PMID: 30568776; PMCID: PMC6251338.
Goulden BD, Pacheco J, Dull A, Zewe JP, Deiters A, Hammond GRV. A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product. J Cell Biol. 2019 Mar 4;218(3):1066-1079. doi: 10.1083/jcb.201809026. PubMed PMID: 30591513; PMCID: PMC6400549.
Kochanek SJ, Close DA, Johnston PA. High Content Screening Characterization of Head and Neck Squamous Cell Carcinoma Multicellular Tumor Spheroid Cultures Generated in 384-Well Ultra-Low Attachment Plates to Screen for Better Cancer Drug Leads. Assay Drug Dev Technol. 2019 Jan;17(1):17-36. doi: 10.1089/adt.2018.896. PubMed PMID: 30592624; PMCID: PMC6352515.
Hurvitz SA, O'Shaughnessy J, Mason G, Yardley DA, Jahanzeb M, Brufsky A, Rugo HS, Swain SM, Kaufman PA, Tripathy D, Chu L, Li H, Antao V, Cobleigh M. Central Nervous System Metastasis in Patients with HER2-Positive Metastatic Breast Cancer: Patient Characteristics, Treatment, and Survival from SystHERs. Clin Cancer Res. 2019 Apr 15;25(8):2433-2441. doi: 10.1158/1078-0432.CCR-18-2366. PubMed PMID: 30593513.
Horne ZD, Karukonda P, Kalash R, Edwards RP, Kelley JL, Comerci JT, Olawaiye AB, Courtney-Brooks M, Bochmeier MM, Berger JL, Taylor SE, Sukumvanich P, Beriwal S. Single-Institution Experience in 3D MRI-Based Brachytherapy for Cervical Cancer for 239 Women: Can Dose Overcome Poor Response? Int J Radiat Oncol Biol Phys. 2019 May 1;104(1):157-164. doi: 10.1016/j.ijrobp.2018.12.042. PubMed PMID: 30605752.
Ren T, Yang M, Xiao M, Zhu J, Xie W, Zuo Z. Time-dependent inhibition of carbamazepine metabolism by piperine in anti-epileptic treatment. Life Sci. 2019 Feb 1;218314-323. doi: 10.1016/j.lfs.2018.12.060. PubMed PMID: 30611786.
Teo PT, Hwang MS, Shields WG, Kosterin P, Jang SY, Heron DE, Lalonde RJ, Huq MS. Application of TG-100 risk analysis methods to the acceptance testing and commissioning process of a Halcyon linear accelerator. Med Phys. 2019 Mar;46(3):1341-1354. doi: 10.1002/mp.13378. PubMed PMID: 30620406.
Tapia-Laliena MÁ, Korzeniewski N, Peña-Llopis S, Scholl C, Fröhling S, Hohenfellner M, Duensing A, Duensing S. Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability. Oncogenesis. 2019 Jan 9;8(1):4. doi: 10.1038/s41389-018-0110-2. PubMed PMID: 30631037; PMCID: PMC6328621.
Man VH, He X, Derreumaux P, Ji B, Xie XQ, Nguyen PH, Wang J. Effects of All-Atom Molecular Mechanics Force Fields on Amyloid Peptide Assembly: The Case of Aβ16-22 Dimer. J Chem Theory Comput. 2019 Feb 12;15(2):1440-1452. doi: 10.1021/acs.jctc.8b01107. PubMed PMID: 30633867.
Haas NB, Appleman LJ, Stein M, Redlinger M, Wilks M, Xu X, Onorati A, Kalavacharla A, Kim T, Zhen CJ, Kadri S, Segal JP, Gimotty PA, Davis LE, Amaravadi RK. Autophagy Inhibition to Augment mTOR Inhibition: a Phase I/II Trial of Everolimus and Hydroxychloroquine in Patients with Previously Treated Renal Cell Carcinoma. Clin Cancer Res. 2019 Apr 1;25(7):2080-2087. doi: 10.1158/1078-0432.CCR-18-2204. PubMed PMID: 30635337.
Ghosh A, Shao L, Sampath P, Zhao B, Patel NV, Zhu J, Behl B, Parise RA, Beumer JH, O'Sullivan RJ, DeLuca NA, Thorne SH, Rathinam VAK, Li P, Sarkar SN. Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production. Immunity. 2019 Jan 15;50(1):51-63.e5. doi: 10.1016/j.immuni.2018.12.013. PubMed PMID: 30635239; PMCID: PMC6342484.
Cotticelli MG, Xia S, Lin D, Lee T, Terrab L, Wipf P, Huryn DM, Wilson RB. Ferroptosis as a Novel Therapeutic Target for Friedreich's Ataxia. J Pharmacol Exp Ther. 2019 Apr;369(1):47-54. doi: 10.1124/jpet.118.252759. PubMed PMID: 30635474.
Schuchert MJ, Normolle DP, Awais O, Pennathur A, Wilson DO, Luketich JD, Landreneau RJ. Factors influencing recurrence following anatomic lung resection for clinical stage I non-small cell lung cancer. Lung Cancer. 2019 Feb;128145-151. doi: 10.1016/j.lungcan.2018.12.026. PubMed PMID: 30642447.
Yan C, Huq MS, Heron DE, Beriwal S, Wynn RB. Correlation between real-time intraoperative and postoperative dosimetry and its implications on intraoperative planning. Brachytherapy. 2019 May - Jun;18(3):338-347. doi: 10.1016/j.brachy.2018.12.004. PubMed PMID: 30655047.
Majzner RG, Theruvath JL, Nellan A, Heitzeneder S, Cui Y, Mount CW, Rietberg SP, Linde MH, Xu P, Rota C, Sotillo E, Labanieh L, Lee DW, Orentas RJ, Dimitrov DS, Zhu Z, Croix BS, Delaidelli A, Sekunova A, Bonvini E, Mitra SS, Quezado MM, Majeti R, Monje M, Sorensen PHB, Maris JM, Mackall CL. CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors. Clin Cancer Res. 2019 Apr 15;25(8):2560-2574. doi: 10.1158/1078-0432.CCR-18-0432. PubMed PMID: 30655315.
Klar N, Brufsky A. Extended adjuvant therapy for early-stage breast cancer: Are there markers for its use? Breast J. 2019 Jan;25(1):7-8. doi: 10.1111/tbj.13038. PubMed PMID: 30659735.
Dai W, Curran DP, Walton JC. EPR and Preparative Studies of 5- endo Cyclizations of Radicals Derived from Alkenyl NHC-Boranes Bearing tert-Butyl Ester Substituents. J Org Chem. 2019 Feb 15;84(4):2102-2111. doi: 10.1021/acs.joc.8b03112. PubMed PMID: 30663305.
Hedberg ML, Peyser ND, Bauman JE, Gooding WE, Li H, Bhola NE, Zhu TR, Zeng Y, Brand TM, Kim MO, Jordan RCK, VandenBerg S, Olivas V, Bivona TG, Chiosea SI, Wang L, Mills GB, Johnson JT, Duvvuri U, Ferris RL, Ha P, Johnson DE, Grandis JR. Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer. J Exp Med. 2019 Feb 4;216(2):419-427. doi: 10.1084/jem.20181936. PubMed PMID: 30683736; PMCID: PMC6363423.
Omana-Zapata I, Mutschmann C, Schmitz J, Gibson S, Judge K, Aruda Indig M, Lu B, Taufman D, Sanfilippo AM, Shallenberger W, Graminske S, McLean R, Hsen RI, d'Empaire N, Dean K, O'Gorman M. Accurate and reproducible enumeration of T-, B-, and NK lymphocytes using the BD FACSLyric 10-color system: A multisite clinical evaluation. PLoS One. 2019;14(1):e0211207. doi: 10.1371/journal.pone.0211207. PubMed PMID: 30689658; PMCID: PMC6349332.
Yepuri N, Bahary N, Jain A, Dhir M. Review and Update on the Role of Peritoneal Cytology in the Treatment of Gastric Cancer. J Surg Res. 2019 Mar;235607-614. doi: 10.1016/j.jss.2018.10.049. PubMed PMID: 30691849.
Sutera P, Kalash R, Clump DA, D'Ambrosio D, Mihai A, Burton SA, Heron DE. Stereotactic Ablative Radiation Therapy for Unresectable Colorectal Oligometastases. Adv Radiat Oncol. 2019 Jan-Mar;4(1):57-62. doi: 10.1016/j.adro.2018.09.001. PubMed PMID: 30706011; PMCID: PMC6349603.
Sukari A, Nagasaka M, Alhasan R, Patel D, Wozniak A, Ramchandren R, Vaishampayan U, Weise A, Flaherty L, Jang H, Kim S, Gadgeel S. Cancer Site and Adverse Events Induced by Immune Checkpoint Inhibitors: A Retrospective Analysis of Real-life Experience at a Single Institution. Anticancer Res. 2019 Feb;39(2):781-790. doi: 10.21873/anticanres.13175. PubMed PMID: 30711957.
Cykert S, Eng E, Walker P, Manning MA, Robertson LB, Arya R, Jones NS, Heron DE. A system-based intervention to reduce Black-White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers. Cancer Med. 2019 Mar;8(3):1095-1102. doi: 10.1002/cam4.2005. PubMed PMID: 30714689; PMCID: PMC6434214.
Dai W, Geib SJ, Curran DP. Ring-Opening Reactions of NHC-Boriranes with In Situ Generated HCl: Synthesis of a New Class of NHC-Boralactones. J Am Chem Soc. 2019 Feb 27;141(8):3623-3629. doi: 10.1021/jacs.8b13010. PubMed PMID: 30717598.
Han M, Salamat A, Zhu L, Zhang H, Clark BZ, Dabbs DJ, Carter GJ, Brufsky AM, Jankowitz RC, Puhalla SL, Johnson RR, Soran A, Steiman JG, McAuliffe PF, Diego EJ, Bhargava R. Metaplastic breast carcinoma: a clinical-pathologic study of 97 cases with subset analysis of response to neoadjuvant chemotherapy. Mod Pathol. 2019 Jun;32(6):807-816. doi: 10.1038/s41379-019-0208-x. PubMed PMID: 30723293.
Nghiem P, Bhatia S, Lipson EJ, Sharfman WH, Kudchadkar RR, Brohl AS, Friedlander PA, Daud A, Kluger HM, Reddy SA, Boulmay BC, Riker AI, Burgess MA, Hanks BA, Olencki T, Margolin K, Lundgren LM, Soni A, Ramchurren N, Church C, Park SY, Shinohara MM, Salim B, Taube JM, Bird SR, Ibrahim N, Fling SP, Homet Moreno B, Sharon E, Cheever MA, Topalian SL. Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy. J Clin Oncol. 2019 Mar 20;37(9):693-702. doi: 10.1200/JCO.18.01896. PubMed PMID: 30726175; PMCID: PMC6424137.
Lukasak B, Morihiro K, Deiters A. Aryl Azides as Phosphine-Activated Switches for Small Molecule Function. Sci Rep. 2019 Feb 6;9(1):1470. doi: 10.1038/s41598-018-37023-6. PubMed PMID: 30728367; PMCID: PMC6365568.
Fan P, Wang N, Wang L, Xie XQ. Autophagy And Apoptosis Specifc Knowledgebases-Guided Systems Pharmacology Drug Research. Curr Cancer Drug Targets. 2019 Feb 6; doi: 10.2174/1568009619666190206122149. PubMed PMID: 30727895.
Smith NG, Gyanchandani R, Shah OS, Gurda GT, Lucas PC, Hartmaier RJ, Brufsky AM, Puhalla S, Bahreini A, Kota K, Wald AI, Nikiforov YE, Nikiforova MN, Oesterreich S, Lee AV. Targeted mutation detection in breast cancer using MammaSeq™. Breast Cancer Res. 2019 Feb 8;21(1):22. doi: 10.1186/s13058-019-1102-7. PubMed PMID: 30736836; PMCID: PMC6368740.
Tasker NR, Rastelli EJ, Blanco IK, Burnett JC, Sharlow ER, Lazo JS, Wipf P. In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors. Org Biomol Chem. 2019 Feb 27;17(9):2448-2466. doi: 10.1039/c9ob00025a. PubMed PMID: 30746541.
Minata M, Audia A, Shi J, Lu S, Bernstock J, Pavlyukov MS, Das A, Kim SH, Shin YJ, Lee Y, Koo H, Snigdha K, Waghmare I, Guo X, Mohyeldin A, Gallego-Perez D, Wang J, Chen D, Cheng P, Mukheef F, Contreras M, Reyes JF, Vaillant B, Sulman EP, Cheng SY, Markert JM, Tannous BA, Lu X, Kango-Singh M, Lee LJ, Nam DH, Nakano I, Bhat KP. Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation. Cell Rep. 2019 Feb 12;26(7):1893-1905.e7. doi: 10.1016/j.celrep.2019.01.076. PubMed PMID: 30759398.
Vujanovic L, Chuckran C, Lin Y, Ding F, Sander CA, Santos PM, Lohr J, Mashadi-Hossein A, Warren S, White A, Huang A, Kirkwood JM, Butterfield LH. CD56dim CD16- Natural Killer Cell Profiling in Melanoma Patients Receiving a Cancer Vaccine and Interferon-α. Front Immunol. 2019;1014. doi: 10.3389/fimmu.2019.00014. PubMed PMID: 30761123; PMCID: PMC6361792.
Kulich S, Becker D, Dacic S, Duvvuri U, Ehsan A, Gutkin D, Hou P, Icardi M, Lyle P, Lynch J, Montgomery B, Passero V, Przygodzki R, Colman H. VHA Practice Guideline Recommendations for Diffuse Gliomas. Fed Pract. 2018 Aug;35(Suppl 5):S28-S35. PubMed PMID: 30766402; PMCID: PMC6248149.
Prabhu AV, Quang TS, Funahashi R, Gupta R, Badeti S, Adeeb N, Moore JM, Agarwal N, Heron DE, Beriwal S. A National WestlawNext Database Analysis of Malpractice Litigation in Radiation Oncology. Fed Pract. 2018 Feb;35(Suppl 1):S44-S52. PubMed PMID: 30766389; PMCID: PMC6375516.
Cramer JD, Samant S, Heron DE, Ferris RL, Kim S. Impact of postoperative radiation therapy for deeply invasive oral cavity cancer upstaged to stage III. Head Neck. 2019 May;41(5):1178-1183. doi: 10.1002/hed.25498. PubMed PMID: 30773733; PMCID: PMC6533633.
Cao L, Wang C, Wipf P. Grob-Type Fragmentation Releases Paracyclophane Ring Strain in a Late-Stage Precursor of Haouamine A. Org Lett. 2019 Mar 1;21(5):1538-1541. doi: 10.1021/acs.orglett.9b00424. PubMed PMID: 30779589.
Wu N, Feng Z, He X, Kwon W, Wang J, Xie XQ. Insight of Captagon Abuse by Chemogenomics Knowledgebase-guided Systems Pharmacology Target Mapping Analyses. Sci Rep. 2019 Feb 19;9(1):2268. doi: 10.1038/s41598-018-35449-6. PubMed PMID: 30783122; PMCID: PMC6381188.
Elsayes KM, Kielar AZ, Chernyak V, Morshid A, Furlan A, Masch WR, Marks RM, Kamaya A, Do RKG, Kono Y, Fowler KJ, Tang A, Bashir MR, Hecht EM, Jambhekar K, Lyshchik A, Rodgers SK, Heiken JP, Kohli M, Fetzer DT, Wilson SR, Kassam Z, Mendiratta-Lala M, Singal AG, Lim CS, Cruite I, Lee J, Ash R, Mitchell DG, McInnes MDF, Sirlin CB. LI-RADS: a conceptual and historical review from its beginning to its recent integration into AASLD clinical practice guidance. J Hepatocell Carcinoma. 2019;649-69. doi: 10.2147/JHC.S186239. PubMed PMID: 30788336; PMCID: PMC6368120.
Alevizakos M, Gaitanidis A, Nasioudis D, Msaouel P, Appleman LJ. Sarcomatoid Renal Cell Carcinoma: Population-Based Study of 879 Patients. Clin Genitourin Cancer. 2019 Jun;17(3):e447-e453. doi: 10.1016/j.clgc.2019.01.005. PubMed PMID: 30799129.
Iheagwara UK, Vargo JA, Chen KS, Burton DR, Taylor SE, Berger JL, Boisen MM, Comerci JT, Orr BC, Sukumvanich P, Olawaiye AB, Kelley JL, Edwards RP, Courtney-Brooks MB, Beriwal S. Neoadjuvant Chemoradiation Therapy Followed by Extrafascial Hysterectomy in Locally Advanced Type II Endometrial Cancer Clinically Extending to Cervix. Pract Radiat Oncol. 2019 Feb 22; doi: 10.1016/j.prro.2019.02.007. PubMed PMID: 30802615.
Ngo M, Wechter N, Tsai E, Shun TY, Gough A, Schurdak ME, Schwacha A, Vogt A. A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics. SLAS Discov. 2019 Jul;24(6):669-681. doi: 10.1177/2472555219829740. PubMed PMID: 30802412; PMCID: PMC6586513.
Poloyac SM, Bertz RJ, McDermott LA, Marathe P. Pharmacological Optimization for Successful Traumatic Brain Injury Drug Development. J Neurotrauma. 2019 Apr 10; doi: 10.1089/neu.2018.6295. PubMed PMID: 30816062.
Wang YQ, Lin WW, Wu N, Wang SY, Chen MZ, Lin ZH, Xie XQ, Feng ZW. Structural insight into the serotonin (5-HT) receptor family by molecular docking, molecular dynamics simulation and systems pharmacology analysis. Acta Pharmacol Sin. 2019 Feb 27; doi: 10.1038/s41401-019-0217-9. PubMed PMID: 30814658.
Kim C, Prabhu AV, Hansberry DR, Agarwal N, Heron DE, Beriwal S. Digital Era of Mobile Communications and Smartphones: A Novel Analysis of Patient Comprehension of Cancer-Related Information Available Through Mobile Applications. Cancer Invest. 2019;37(3):127-133. doi: 10.1080/07357907.2019.1572760. PubMed PMID: 30821518.
Barbosa ACS, Feng Y, Yu C, Huang M, Xie W. Estrogen sulfotransferase in the metabolism of estrogenic drugs and in the pathogenesis of diseases. Expert Opin Drug Metab Toxicol. 2019 Apr;15(4):329-339. doi: 10.1080/17425255.2019.1588884. PubMed PMID: 30822161; PMCID: PMC6428602.
Abecassis I, Sedgewick AJ, Romkes M, Buch S, Nukui T, Kapetanaki MG, Vogt A, Kirkwood JM, Benos PV, Tawbi H. PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy. Sci Rep. 2019 Mar 1;9(1):3309. doi: 10.1038/s41598-019-39542-2. PubMed PMID: 30824778; PMCID: PMC6397203.
Klar N, Rosenzweig M, Diergaarde B, Brufsky A. Features Associated With Long-Term Survival in Patients With Metastatic Breast Cancer. Clin Breast Cancer. 2019 Feb 6; doi: 10.1016/j.clbc.2019.01.014. PubMed PMID: 30827763.
Albrecht TA, Keim-Malpass J, Boyiadzis M, Rosenzweig M. Psychosocial Experiences of Young Adults Diagnosed With Acute Leukemia During Hospitalization for Induction Chemotherapy Treatment. J Hosp Palliat Nurs. 2019 Apr;21(2):167-173. doi: 10.1097/NJH.0000000000000545. PubMed PMID: 30829935; PMCID: PMC6400296.
Singhi AD, George B, Greenbowe JR, Chung J, Suh J, Maitra A, Klempner SJ, Hendifar A, Milind JM, Golan T, Brand RE, Zureikat AH, Roy S, Schrock AB, Miller VA, Ross JS, Ali SM, Bahary N. Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers. Gastroenterology. 2019 Jun;156(8):2242-2253.e4. doi: 10.1053/j.gastro.2019.02.037. PubMed PMID: 30836094.
Ganguly A, Frank D, Kumar N, Cheng YC, Chu E. Cancer Biomarkers for Integrative Oncology. Curr Oncol Rep. 2019 Mar 5;21(4):32. doi: 10.1007/s11912-019-0782-6. PubMed PMID: 30834992.
Chen M, Jing Y, Wang L, Feng Z, Xie XQ. DAKB-GPCRs: An Integrated Computational Platform for Drug Abuse Related GPCRs. J Chem Inf Model. 2019 Apr 22;59(4):1283-1289. doi: 10.1021/acs.jcim.8b00623. PubMed PMID: 30835466.
Ge H, Bian Y, He X, Xie XQ, Wang J. Significantly different effects of tetrahydroberberrubine enantiomers on dopamine D1/D2 receptors revealed by experimental study and integrated in silico simulation. J Comput Aided Mol Des. 2019 Apr;33(4):447-459. doi: 10.1007/s10822-019-00194-z. PubMed PMID: 30840169.
Xu W, Qian J, Zeng F, Li S, Guo W, Chen L, Li G, Zhang Z, Wang QJ, Deng F. Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment. J Exp Clin Cancer Res. 2019 Mar 6;38(1):114. doi: 10.1186/s13046-019-1118-y. PubMed PMID: 30841931; PMCID: PMC6404326.
Jiang X, Wells A, Brufsky A, Neapolitan R. A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis. PLoS One. 2019;14(3):e0213292. doi: 10.1371/journal.pone.0213292. PubMed PMID: 30849111; PMCID: PMC6407919.
Ward MC, Lee NY, Caudell JJ, Zajichek A, Awan MJ, Koyfman SA, Dunlap NE, Zakem SJ, Hassanzadeh C, Marcrom S, Boggs DH, Isrow D, Vargo JA, Heron DE, Siddiqui F, Bonner JA, Beitler JJ, Yao M, Trotti AM, Riaz N, Multi-Institution Re-Irradiation (MIRI) Collaborative.. A competing risk nomogram to predict severe late toxicity after modern re-irradiation for squamous carcinoma of the head and neck. Oral Oncol. 2019 Mar;9080-86. doi: 10.1016/j.oraloncology.2019.01.022. PubMed PMID: 30846182.
Weiss J, Kavanagh B, Deal A, Villaruz L, Stevenson J, Camidge R, Borghaei H, West J, Kirpalani P, Morris D, Lee C, Pecot CV, Zagar T, Stinchcombe T, Pennell N. Phase II study of stereotactic radiosurgery for the treatment of patients with oligoprogression on erlotinib. Cancer Treat Res Commun. 2019;19100126. doi: 10.1016/j.ctarc.2019.100126. PubMed PMID: 30852467.
Heinrich MC, Patterson J, Beadling C, Wang Y, Debiec-Rychter M, Dewaele B, Corless CL, Duensing A, Raut CP, Rubin B, Ordog T, van de Rijn M, Call J, Mühlenberg T, Fletcher JA, Bauer S. Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs). Clin Sarcoma Res. 2019;93. doi: 10.1186/s13569-019-0112-7. PubMed PMID: 30867899; PMCID: PMC6399846.
Kim RS, Song N, Gavin PG, Salgado R, Bandos H, Kos Z, Floris G, Eynden GGVD, Badve S, Demaria S, Rastogi P, Fehrenbacher L, Mamounas EP, Swain SM, Lawrence Wickerham D, Costantino JP, Paik S, Wolmark N, Geyer CE, Lucas PC, Pogue-Geile KL. Stromal Tumor-infiltrating Lymphocytes in NRG Oncology/NSABP B-31 Adjuvant Trial for Early-stage HER2-positive Breast Cancer. J Natl Cancer Inst. 2019 Mar 19; doi: 10.1093/jnci/djz032. PubMed PMID: 30888406.
Gubens MA, Sequist LV, Stevenson JP, Powell SF, Villaruz LC, Gadgeel SM, Langer CJ, Patnaik A, Borghaei H, Jalal SI, Fiore J, Saraf S, Raftopoulos H, Gandhi L. Pembrolizumab in combination with ipilimumab as second-line or later therapy for advanced non-small-cell lung cancer: KEYNOTE-021 cohorts D and H. Lung Cancer. 2019 Apr;13059-66. doi: 10.1016/j.lungcan.2018.12.015. PubMed PMID: 30885353.
Shimoi M, Maeda K, Geib SJ, Curran DP, Taniguchi T. Esters as Radical Acceptors: β-NHC-Borylalkenyl Radicals Induce Lactonization by C-C Bond Formation/Cleavage on Esters. Angew Chem Int Ed Engl. 2019 May 6;58(19):6357-6361. doi: 10.1002/anie.201902001. PubMed PMID: 30891902.
Casal MA, Nolin TD, Beumer JH. Estimation of Kidney Function in Oncology: Implications for Anticancer Drug Selection and Dosing. Clin J Am Soc Nephrol. 2019 Apr 5;14(4):587-595. doi: 10.2215/CJN.11721018. PubMed PMID: 30890575; PMCID: PMC6450339.
Cavallari LH, Van Driest SL, Prows CA, Bishop JR, Limdi NA, Pratt VM, Ramsey LB, Smith DM, Tuteja S, Duong BQ, Hicks JK, Lee JC, Obeng AO, Beitelshees AL, Bell GC, Blake K, Crona DJ, Dressler L, Gregg RA, Hines LJ, Scott SA, Shelton RC, Weitzel KW, Johnson JA, Peterson JF, Empey PE, Skaar TC, IGNITE Network.. Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing. Genet Med. 2019 Mar 21; doi: 10.1038/s41436-019-0484-3. PubMed PMID: 30894703.
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S, CommonMind Consortium., Schizophrenia Working Group of the Psychiatric Genomics Consortium., iPSYCH-GEMS Schizophrenia Working Group., Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038/s41588-019-0364-4. PubMed PMID: 30911161.
Shurin GV, Kruglov O, Ding F, Lin Y, Hao X, Keskinov AA, You Z, Lokshin AE, LaFramboise WA, Falo LD Jr, Shurin MR, Bunimovich YL. Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth. Cancer Res. 2019 May 15;79(10):2736-2747. doi: 10.1158/0008-5472.CAN-18-3872. PubMed PMID: 30914431; PMCID: PMC6522315.
Cykert S, Eng E, Manning MA, Robertson LB, Heron DE, Jones NS, Schaal JC, Lightfoot A, Zhou H, Yongue C, Gizlice Z. A Multi-faceted Intervention Aimed at Black-White Disparities in the Treatment of Early Stage Cancers: The ACCURE Pragmatic Quality Improvement trial. J Natl Med Assoc. 2019 Mar 27; doi: 10.1016/j.jnma.2019.03.001. PubMed PMID: 30928088.
Wan Z, Sun J, Xu J, Moharil P, Chen J, Xu J, Zhu J, Li J, Huang Y, Xu P, Ma X, Xie W, Lu B, Li S. Dual functional immunostimulatory polymeric prodrug carrier with pendent indoximod for enhanced cancer immunochemotherapy. Acta Biomater. 2019 May;90300-313. doi: 10.1016/j.actbio.2019.03.048. PubMed PMID: 30930305; PMCID: PMC6513707.
Bezjak A, Paulus R, Gaspar LE, Timmerman RD, Straube WL, Ryan WF, Garces YI, Pu AT, Singh AK, Videtic GM, McGarry RC, Iyengar P, Pantarotto JR, Urbanic JJ, Sun AY, Daly ME, Grills IS, Sperduto P, Normolle DP, Bradley JD, Choy H. Safety and Efficacy of a Five-Fraction Stereotactic Body Radiotherapy Schedule for Centrally Located Non-Small-Cell Lung Cancer: NRG Oncology/RTOG 0813 Trial. J Clin Oncol. 2019 May 20;37(15):1316-1325. doi: 10.1200/JCO.18.00622. PubMed PMID: 30943123; PMCID: PMC6524984.
An Y, Wang P, Xu P, Tung HC, Xie Y, Kirisci L, Xu M, Ren S, Tian X, Ma X, Xie W. An Unexpected Role of Cholesterol Sulfotransferase and its Regulation in Sensitizing Mice to Acetaminophen-Induced Liver Injury. Mol Pharmacol. 2019 Jun;95(6):597-605. doi: 10.1124/mol.118.114819. PubMed PMID: 30944208; PMCID: PMC6491915.
Weekes C, Lockhart AC, Lee JJ, Sturm I, Cleton A, Huang F, Lenz HJ. A phase 1b study evaluating the safety and pharmacokinetics of regorafenib in combination with cetuximab in patients with advanced solid tumors. Int J Cancer. 2019 Apr 8; doi: 10.1002/ijc.32317. PubMed PMID: 30958892.
Lopez LV, Yatsenko SA, Burgess M, Schoedel K, Rao UNM. Dermatofibrosarcoma protuberans with fibrosarcomatous transformation: our experience, molecular evaluation of selected cases, and short literature review. Int J Dermatol. 2019 Apr 10; doi: 10.1111/ijd.14462. PubMed PMID: 30968395.
Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10; doi: 10.1136/gutjnl-2018-317817. PubMed PMID: 30971436.
Jonna S, Feldman RA, Swensen J, Gatalica Z, Korn WM, Borghaei H, Ma PC, Nieva JJ, Spira AI, Vanderwalde AM, Wozniak AJ, Kim ES, Liu SV. Detection of NRG1 Gene Fusions in Solid Tumors. Clin Cancer Res. 2019 Apr 15; doi: 10.1158/1078-0432.CCR-19-0160. PubMed PMID: 30988082.
Li Y, Pu S, Liu Q, Li R, Zhang J, Wu T, Chen L, Li H, Yang X, Zou M, Xiao J, Xie W, He J. An integrin-based nanoparticle that targets activated hepatic stellate cells and alleviates liver fibrosis. J Control Release. 2019 Jun 10;30377-90. doi: 10.1016/j.jconrel.2019.04.022. PubMed PMID: 31004666.
Gebhardt BJ, Rangaswamy B, Thomas J, Kelley J, Sukumvanich P, Edwards R, Comerci J, Olawaiye A, Courtney-Brooks M, Boisen M, Berger J, Beriwal S. Magnetic resonance imaging response in patients treated with definitive radiation therapy for medically inoperable endometrial cancer-Does it predict treatment response? Brachytherapy. 2019 Apr 17; doi: 10.1016/j.brachy.2019.03.005. PubMed PMID: 31005602.
Maganty A, Turner RM 2nd, Yabes JG, Davies BJ, Heron DE, Jacobs BL. Downstream Studies Following the Use of Bone Scan in the Staging of Muscle-invasive Bladder Cancer. Urology. 2019 Apr 18; doi: 10.1016/j.urology.2019.04.009. PubMed PMID: 31005656.
Bernard ME, Sutera PA, Iarrobino NA, Quan K, Burton SA, Bahary N, Hogg M, Zureikat A, Heron DE. Initial Results of a Prospective Study of Adjuvant Pancreatic Stereotactic Body Radiation Therapy for Close or Positive Margins. Adv Radiat Oncol. 2019 Apr-Jun;4(2):294-301. doi: 10.1016/j.adro.2018.11.007. PubMed PMID: 31011674; PMCID: PMC6460098.
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Kochanek SJ, Close DA, Wang AX, Shun T, Empey PE, Eiseman JL, Johnston PA. Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy. SLAS Discov. 2019 Jul;24(6):653-668. doi: 10.1177/2472555219844566. PubMed PMID: 31039321.
Xie Y, Xu M, Deng M, Li Z, Wang P, Ren S, Guo Y, Ma X, Fan J, Billiar TR, Xie W. Activation of Pregnane X Receptor Sensitizes Mice to Hemorrhagic Shock Induced Liver Injury. Hepatology. 2019 Apr 30; doi: 10.1002/hep.30691. PubMed PMID: 31038762.
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Yamada T, Hamada M, Floreancig P, Nakabachi A. Diaphorin, a polyketide synthesized by an intracellular symbiont of the Asian citrus psyllid, is potentially harmful for biological control agents. PLoS One. 2019;14(5):e0216319. doi: 10.1371/journal.pone.0216319. PubMed PMID: 31048920; PMCID: PMC6497295.
Xu J, Sun J, Ho PY, Luo Z, Ma W, Zhao W, Rathod SB, Fernandez CA, Venkataramanan R, Xie W, Yu AM, Li S. Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis. Biomaterials. 2019 Jul;21025-40. doi: 10.1016/j.biomaterials.2019.04.025. PubMed PMID: 31054369; PMCID: PMC6538300.
Kho DH, Uddin MH, Chatterjee M, Vogt A, Raz A, Wu GS. GP78 Cooperates with Dual-Specificity Phosphatase 1 To Stimulate Epidermal Growth Factor Receptor-Mediated Extracellular Signal-Regulated Kinase Signaling. Mol Cell Biol. 2019 Jun 1;39(11): doi: 10.1128/MCB.00485-18. PubMed PMID: 31061093; PMCID: PMC6517599.
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Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S, CommonMind Consortium., Schizophrenia Working Group of the Psychiatric Genomics Consortium., iPSYCH-GEMS Schizophrenia Working Group., Demontis D, Børglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA. Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038/s41588-019-0435-6. PubMed PMID: 31086353.
Donnenberg AD, Kanias T, Triulzi DJ, Dennis CJ, Moore LR, Meyer EM, Sinchar D, Kiss JE, Normolle DP, Gladwin MT. Current good manufacturing practices-compliant manufacture and measurement of biotin-labeled red blood cells. Cytotherapy. 2019 May 13; doi: 10.1016/j.jcyt.2019.04.052. PubMed PMID: 31097327.
Zhou Z, Feng Z, Hu D, Yang P, Gur M, Bahar I, Cristofanilli M, Gradishar WJ, Xie XQ, Wan Y. A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy. EBioMedicine. 2019 May 14; doi: 10.1016/j.ebiom.2019.05.011. PubMed PMID: 31101597.
Brufsky A, Mitra D, Davis KL, Nagar SP, McRoy L, Cotter MJ, Stearns V. Treatment Patterns and Outcomes Associated With Palbociclib Plus Letrozole for Postmenopausal Women With HR-/HER2- Advanced Breast Cancer Enrolled in an Expanded Access Program. Clin Breast Cancer. 2019 Apr 18; doi: 10.1016/j.clbc.2019.04.005. PubMed PMID: 31104984.
Bardhan A, Deiters A. Development of photolabile protecting groups and their application to the optochemical control of cell signaling. Curr Opin Struct Biol. 2019 May 24;57164-175. doi: 10.1016/j.sbi.2019.03.028. PubMed PMID: 31132552.
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Theodoraki MN, Yerneni S, Gooding WE, Ohr J, Clump DA, Bauman JE, Ferris RL, Whiteside TL. Circulating exosomes measure responses to therapy in head and neck cancer patients treated with cetuximab, ipilimumab, and IMRT. Oncoimmunology. 2019;8(7):1593805. doi: 10.1080/2162402X.2019.1593805. PubMed PMID: 31143513; PMCID: PMC6527269.
Ling DC, Vargo JA, Burton SA, Heron DE, Beriwal S. Salvage Curative-Intent Re-irradiation Stereotactic Body Radiation Therapy for Isolated, Pelvic and/or Para-aortic Recurrences of Gynecologic Malignancies. Pract Radiat Oncol. 2019 May 28; doi: 10.1016/j.prro.2019.05.012. PubMed PMID: 31150869.
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Kim H, Huq MS, Heron DE, Lalonde R, Houser CJ, Champ CE, Beriwal S. Assessment of deep inspiration breath hold technique setup reproducibility using mega voltage imaging for left breast cancer radiation therapy-integrated network study. Med Dosim. 2019 May 29; doi: 10.1016/j.meddos.2019.04.006. PubMed PMID: 31153678.
Yan J, Tung HC, Li S, Niu Y, Garbacz WG, Lu P, Bi Y, Li Y, He J, Xu M, Ren S, Monga SP, Schwabe RF, Yang D, Xie W. Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice. Gastroenterology. 2019 Jun 3; doi: 10.1053/j.gastro.2019.05.066. PubMed PMID: 31170413.
Miedel MT, Gavlock DC, Jia S, Gough A, Taylor DL, Stern AM. Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System. Sci Rep. 2019 Jun 6;9(1):8341. doi: 10.1038/s41598-019-44756-5. PubMed PMID: 31171849; PMCID: PMC6554298.
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Turner MT, Geltzeiler M, Albergotti WG, Duvvuri U, Ferris RL, Kim S, Wang EW. Reconstruction of TORS oropharyngectomy defects with the nasoseptal flap via transpalatal tunnel. J Robot Surg. 2019 Jun 10; doi: 10.1007/s11701-019-00984-5. PubMed PMID: 31183606.
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Taylor DL, Gough A, Schurdak ME, Vernetti L, Chennubhotla CS, Lefever D, Pei F, Faeder JR, Lezon TR, Stern AM, Bahar I. Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology. Handb Exp Pharmacol. 2019 Jun 15; doi: 10.1007/164_2019_239. PubMed PMID: 31201557.
Garcia CA, Bhatnagar M, Rodenbach R, Chu E, Marks S, Graham-Pardus A, Kriner J, Winfield M, Minnier C, Leahy J, Hanchett S, Baird E, Arnold RM, Levenson JE. Standardization of Inpatient CPR Status Discussions and Documentation Within the Division of Hematology-Oncology at UPMC Shadyside: Results From PDSA Cycles 1 and 2. J Oncol Pract. 2019 Jun 17;JOP1800416. doi: 10.1200/JOP.18.00416. PubMed PMID: 31206337.
Feng Y, Xie Y, Xu M, Li L, Selcer KW, Oberly PJ, Poloyac SM, Wang H, Li C, Dong F, Yu C, Xie W. Hepatic steroid sulfatase critically determines estrogenic activities of conjugated equine estrogens in human cells in vitro and in mice. J Biol Chem. 2019 Jun 19; doi: 10.1074/jbc.RA119.009181. PubMed PMID: 31217279.
Liu R, Tzounopoulos T, Wipf P. Synthesis and Optimization of Kv7 (KCNQ) Potassium Channel Agonists: The Role of Fluorines in Potency and Selectivity. ACS Med Chem Lett. 2019 Jun 13;10(6):929-935. doi: 10.1021/acsmedchemlett.9b00097. PubMed PMID: 31223450; PMCID: PMC6580556.
Long K, Kostman SJ, Fernandez C, Burnett JC, Huryn DM. Do Zebrafish Obey Lipinski Rules? ACS Med Chem Lett. 2019 Jun 13;10(6):1002-1006. doi: 10.1021/acsmedchemlett.9b00063. PubMed PMID: 31223462; PMCID: PMC6580538.
Blanco MJ, Huryn DM. Women in Medicinal Chemistry Special Issue. ACS Med Chem Lett. 2019 Jun 13;10(6):834. doi: 10.1021/acsmedchemlett.9b00199. PubMed PMID: 31223431; PMCID: PMC6580375.