Program: Cancer Therapeutics
The Wipf group develops tools of synthetic organic chemistry in the search for innovative new therapies and therapeutics. We identify original synthetic methods, strategies and molecular mechanisms, and we apply them in medicinal chemistry and chemical biology, total synthesis, and natural products chemistry. We select target molecules on the basis of their unique architectures and biological activities, as well as for showcasing our synthetic methods. We employ insights from flow and photochemistry, material science and nanoparticle research to improve synthetic access and modify the properties of our target compounds. Most significantly, we are committed to collaborative drug discovery and development in diverse therapeutic areas, including oncology, neurodegeneration, fibrosis, neuromuscular diseases, inflammation, and immunology.
Research Interests and Keywords
- Anti-cancer therapeutics,Anti-Inflammatory Agents,Drug Discovery,heterocyclic chemistry,kinase inhibitors,medicinal chemistry,mitochondrial targeting,natural products,organic synthesis,radiation dermatitis,radiation mitigation,Radiation Protection,reactive oxygen species scavengers,Toll-Like Receptors