Investigators

Summary

Dr. Jacobs’ research interests focus on improving the access, delivery, and quality of care, particularly for traditionally underserved populations. He has over 100 publications, including studies in high-impact journals such as JAMA, Health Affairs, and Cancer. He is the principal investigator on an R37 MERIT award from the National Cancer Institute and has received grant support from several other agencies, including the National Institute on Aging, the American Cancer Society, and the Shadyside Hospital Foundation. He is the Research Chief of the Urology Health…

Summary

Kaposi's sarcoma-associated herpesvirus (KSHV), or HHV-8, is a member of the human herpesvirus family whose DNA sequences have been found in samples of Kaposi's sarcoma (KS). A number of projects in our laboratory are focused on the prevalence of KSHV infection in various cohorts and populations. We are particularly interested in the serological association of KSHV with human prostate cancer and are investigating at a molecular level, potential roles for KSHV in progression and maintenance of this cancer. We are also exploring the events during primary KSHV infection, including…

Summary

The research in my laboratory focuses on using T cell antigen discovery techniques to understand and engineer immunity. One of the areas we are interested in is uncovering the targets of antitumor T cell responses and using this knowledge to engineer novel therapies.

Summary

Dr. Johnston has over two decades of drug discovery experience in the pharmaceutical, biotechnology and academic sectors. Since joining the University of Pittsburgh Department of Pharmacology & Chemical Biology in 2005 to help design and build the infrastructure for a high-throughput drug discovery screening center at the Drug Discovery Institute, Dr. Johnston has led 21 screening campaigns, and reconfigured the NCI 60 cell line assays for cancer drug combination screening. In 2011, Dr. Johnston joined the Department of Pharmaceutical Sciences in the School of Pharmacy to establish…

Summary

I am PhD investigator and medical physicist with expertise in radiopharmaceutical dosimetry and modelling as well as PET- and SPECT-imaged based dosimetry. During my PhD studies, I developed small scale/micro dosimetry models for the thyroid gland to calculate the radiation absorbed doses when treated or exposed to α-particle or Auger-electron emitting radiohalogens (e.g., Astatine and Iodine isotopes). My post-doctoral work and research as a faculty at Johns Hopkins University focused on pre-clinical and clinical projects regarding image quantification and dosimetry of…