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Gabriel Sica

Gabriel Sica

Program: Cancer Therapeutics

(412) 647-3238 UPMC Presbyterian Hospital
200 Lothrop St
Pittsburgh PA

My research has focused predominantly in the pathobiology of lung cancer and how the tumor microenvironment affects the natural biology and response to treatment. Working in collaboration with colleagues from the department of medical oncology we have discovered multiple possible biomarkers for disease management. In the future, I would like to integrate digital pathology analysis platforms into these studies. Specific topics of current investigation include: 1) Small cell lung carcinoma subtypes and genomics; 2) Morphologic features of lung cancer and its stroma, impact on natural biology; 3) Grading of Neuroendocrine Tumors; 4) Senescence in lung carcinoma immune response. In addition, in my role as the co-director of TARPS and as a member of TPIL, I hope to facilitate team based science, especially with regard to tissue based investigations.

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