Cancer Bioinformatics Services (CBS) provides comprehensive bioinformatics support for translational genomics at UPMC Hillman Cancer Center. CBS provides support for all aspects of genomics studies, from experimental design to data analysis to publication, and for all genomic Next Generation Sequencing (NGS) applications, including RNA Seq, WES, WGS, ATAC Seq, single cell RNA Seq, immunogenomics profiling, neoantigen prediction, microbiome 16S rRNA-gene amplicon and metagenomics shotgun sequencing. CBS also works closely with the computing resources such as the Pittsburgh Supercomputing Center (PSC) and the University of Pittsburgh’s Center for Research Computing (CRC). CBS teaches genomics classes at the Health Science Library System (HSLC) and CRC. CBS supports small projects to larger team science projects such as the Big Data to Knowledge (BD2K), PACURE’s Big Data for Better Health (BD4BH), Breast Cancer Research Foundations AURORA project on metastatic breast cancer and HCC’s SPORE programs.