Summary
Dr. Ray's primary research interest is in immune regulation of inflammatory diseases of the lung and the gut. Early research from her laboratory led to the identification of NF-kB as a target for glucocorticoid-mediated repression of gene expression and the discovery of GATA-3 as a master regulator of Th2 cells. More recent work from her laboratory has identified a key role for Tregs expressing membrane-bound TGF-beta with cross-talk with the Notch pathway in the regulation of immune tolerance in the airways.