Donald DeFranco, PhD

Summary

Dr. DeFranco's laboratory examines glucocorticoid receptor function, focusing predominantly on the mechanisms of glucocorticoid receptor transactivation, interaction with coactivators, subcellular and subnuclear trafficking, interactions with molecular chaperones and processing. Dr. DeFranco is also interested in androgen receptor and estrogen receptor function, with a particular emphasis on examining coregulators that impact androgen action in prostate and the regulation of estrogen receptor function by oxidative stress and TGF' signaling.