Summary
Dr. Hegde is a cancer researcher focused on translational drug development for hematologic malignancies, including acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPNs). Her research integrates molecular and cellular biology, patient-derived models, and in vivo studies to identify and develop targeted therapies for genetically defined leukemia subtypes, with a particular focus on JAK2-driven malignancies and therapy resistance. Her work aims to translate mechanistic discoveries into more effective and less toxic therapeutic strategies that improve outcomes for patients with blood cancers.