Selected Member Publications

Ko S, Monga SP. The dark side of human hepatocyte plasticity. Gastroenterology. 2024-06-25; doi: 10.1053/j.gastro.2024.06.011. nihFormattedCitation: Ko S, Monga SP. The dark side of human hepatocyte plasticity. Gastroenterology. 2024;.. PubMed PMID: 38936779.
Scott AL, Jazwinska DE, Kulawiec DG, Zervantonakis IK. Paracrine Ovarian Cancer Cell-Derived CSF1 Signaling Regulates Macrophage Migration Dynamics in a 3D Microfluidic Model that Recapitulates in vivo Infiltration Patterns in Patient-Derived Xenografts. Adv Healthc Mater. 2024-05-28;e2401719. doi: 10.1002/adhm.202401719. nihFormattedCitation: Scott AL, Jazwinska DE, Kulawiec DG, Zervantonakis IK. Paracrine Ovarian Cancer Cell-Derived CSF1 Signaling Regulates Macrophage Migration Dynamics in a 3D Microfluidic Model that Recapitulates in vivo Infiltration Patterns in Patient-Derived Xenografts. Adv Healthc Mater. 2024;:e2401719.. PubMed PMID: 38807270.
Steinman RA, Gandy LM, Qi H, Fertig EJ, Blackford AL, Grandis JR. Career trajectories of MD-PhD physician scientists: The loss of women investigators. Cancer Cell. 2024-05-13; doi: 10.1016/j.ccell.2024.04.006. nihFormattedCitation: Steinman RA, Gandy LM, Qi H, Fertig EJ, Blackford AL, Grandis JR. Career trajectories of MD-PhD physician scientists: The loss of women investigators. Cancer Cell. 2024;.. PubMed PMID: 38701793.
Augustin RC, Cai WL, Luke JJ, Bao R. Facts and hopes in using omics to advance combined immunotherapy strategies. Clin Cancer Res. 2024-05-01; doi: 10.1158/1078-0432.CCR-22-2241. nihFormattedCitation: Augustin RC, Cai WL, Luke JJ, Bao R. Facts and hopes in using omics to advance combined immunotherapy strategies. Clin Cancer Res. 2024;. PMCID: PMC11062841.. PubMed PMID: 38236069; PMCID: PMC11062841.
Chen L, Wang Y, Cai C, Ding Y, Kim RS, Lipchik C, Gavin PG, Yothers G, Allegra CJ, Petrelli NJ, Suga JM, Hopkins JO, Saito NG, Evans T, Jujjavarapu S, Wolmark N, Lucas PC, Paik S, Sun M, Pogue-Geile KL, Lu X. Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. J Clin Oncol. 2024-05-01;JCO2301080. doi: 10.1200/JCO.23.01080. nihFormattedCitation: Chen L, Wang Y, Cai C, Ding Y, Kim RS, Lipchik C, Gavin PG, Yothers G, Allegra CJ, Petrelli NJ, Suga JM, Hopkins JO, Saito NG, Evans T, Jujjavarapu S, Wolmark N, Lucas PC, Paik S, Sun M, Pogue-Geile KL, Lu X. Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. J Clin Oncol. 2024;:JCO2301080. PMCID: PMC11095904.. PubMed PMID: 38315963; PMCID: PMC11095904.
Rumde PH, Burns TF. A Path to Persistence after EGFR Inhibition. Cancer Res. 2024-04-15;84(8):1188-1190. doi: 10.1158/0008-5472.CAN-24-0274. nihFormattedCitation: Rumde PH, Burns TF. A Path to Persistence after EGFR Inhibition. Cancer Res. 2024;84(8):1188-1190. PMCID: PMC11090642.. PubMed PMID: 38616658; PMCID: PMC11090642.
Wang Y, Pattarayan D, Huang H, Zhao Y, Li S, Wang Y, Zhang M, Li S, Yang D. Systematic investigation of chemo-immunotherapy synergism to shift anti-PD-1 resistance in cancer. Nat Commun. 2024-04-12;15(1):3178. doi: 10.1038/s41467-024-47433-y. nihFormattedCitation: Wang Y, Pattarayan D, Huang H, Zhao Y, Li S, Wang Y, Zhang M, Li S, Yang D. Systematic investigation of chemo-immunotherapy synergism to shift anti-PD-1 resistance in cancer. Nat Commun. 2024;15(1):3178. PMCID: PMC11015024.. PubMed PMID: 38609378; PMCID: PMC11015024.
Berg WA, Berg JM, Bandos AI, Vargo A, Chough DM, Lu AH, Ganott MA, Kelly AE, Nair BE, Hartman JY, Waheed U, Hakim CM, Harnist KS, Reginella RF, Shinde DD, Carlin BA, Cohen CS, Wallace LP, Sumkin JH, Zuley ML. Addition of Contrast-enhanced Mammography to Tomosynthesis for Breast Cancer Detection in Women with a Personal History of Breast Cancer: Prospective TOCEM Trial Interim Analysis. Radiology. 2024-04-01;311(1):e231991. doi: 10.1148/radiol.231991. nihFormattedCitation: Berg WA, Berg JM, Bandos AI, Vargo A, Chough DM, Lu AH, Ganott MA, Kelly AE, Nair BE, Hartman JY, Waheed U, Hakim CM, Harnist KS, Reginella RF, Shinde DD, Carlin BA, Cohen CS, Wallace LP, Sumkin JH, Zuley ML. Addition of Contrast-enhanced Mammography to Tomosynthesis for Breast Cancer Detection in Women with a Personal History of Breast Cancer: Prospective TOCEM Trial Interim Analysis. Radiology. 2024;311(1):e231991. PMCID: PMC11070607.. PubMed PMID: 38687218; PMCID: PMC11070607.
Zhang H, Lee S, Muthakana RR, Lu B, Boone DN, Lee D, Wang XS. Intragenic Rearrangement Burden Associates with Immune Cell Infiltration and Response to Immune Checkpoint Blockade in Cancer. Cancer Immunol Res. 2024-03-04;OF1-OF9. doi: 10.1158/2326-6066.CIR-22-0637. nihFormattedCitation: Zhang H, Lee S, Muthakana RR, Lu B, Boone DN, Lee D, Wang XS. Intragenic Rearrangement Burden Associates with Immune Cell Infiltration and Response to Immune Checkpoint Blockade in Cancer. Cancer Immunol Res. 2024;:OF1-OF9. PMCID: PMC11107381.. PubMed PMID: 38345376; PMCID: PMC11107381.
Bailey KM. Therapeutic Hope on the Surface of Ewing Sarcoma. Clin Cancer Res. 2024-03-01; doi: 10.1158/1078-0432.CCR-23-3138. nihFormattedCitation: Bailey KM. Therapeutic Hope on the Surface of Ewing Sarcoma. Clin Cancer Res. 2024;. PMCID: PMC10922950.. PubMed PMID: 38113033; PMCID: PMC10922950.
Casillo SM, Gatesman TA, Chilukuri A, Varadharajan S, Johnson BJ, David Premkumar DR, Jane EP, Plute TJ, Koncar RF, Stanton AJ, Biagi-Junior CAO, Barber CS, Halbert ME, Golbourn BJ, Halligan K, Cruz AF, Mansi NM, Cheney A, Mullett SJ, Land CV, Perez JL, Myers MI, Agrawal N, Michel JJ, Chang YF, Vaske OM, MichaelRaj A, Lieberman FS, Felker J, Shiva S, Bertrand KC, Amankulor N, Hadjipanayis CG, Abdullah KG, Zinn PO, Friedlander RM, Abel TJ, Nazarian J, Venneti S, Filbin MG, Gelhaus SL, Mack SC, Pollack IF, Agnihotri S. An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma. Cell Rep. 2024-01-23;43(1):113557. doi: 10.1016/j.celrep.2023.113557. nihFormattedCitation: Casillo SM, Gatesman TA, Chilukuri A, Varadharajan S, Johnson BJ, David Premkumar DR, Jane EP, Plute TJ, Koncar RF, Stanton AJ, Biagi-Junior CAO, Barber CS, Halbert ME, Golbourn BJ, Halligan K, Cruz AF, Mansi NM, Cheney A, Mullett SJ, Land CV, Perez JL, Myers MI, Agrawal N, Michel JJ, Chang YF, Vaske OM, MichaelRaj A, Lieberman FS, Felker J, Shiva S, Bertrand KC, Amankulor N, Hadjipanayis CG, Abdullah KG, Zinn PO, Friedlander RM, Abel TJ, Nazarian J, Venneti S, Filbin MG, Gelhaus SL, Mack SC, Pollack IF, Agnihotri S. An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma. Cell Rep. 2024;43(1):113557.. PubMed PMID: 38113141.
Lv D, Zhong C, Dixit D, Yang K, Wu Q, Godugu B, Prager BC, Zhao G, Wang X, Xie Q, Bao S, He C, Heiland DH, Rosenfeld MG, Rich JN. EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma. Mol Cell. 2023-12-07; doi: 10.1016/j.molcel.2023.10.025. nihFormattedCitation: Lv D, Zhong C, Dixit D, Yang K, Wu Q, Godugu B, Prager BC, Zhao G, Wang X, Xie Q, Bao S, He C, Heiland DH, Rosenfeld MG, Rich JN. EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma. Mol Cell. 2023;. PMCID: PMC10842222.. PubMed PMID: 37979586; PMCID: PMC10842222.
Marti JLG, Wells JZ, Wells A. Statins as a Secondary Preventive Agent for Metastatic Cancer. J Thorac Oncol. 2023-11-01;18(11):e125-e126. doi: 10.1016/j.jtho.2023.07.027. nihFormattedCitation: Marti JLG, Wells JZ, Wells A. Statins as a Secondary Preventive Agent for Metastatic Cancer. J Thorac Oncol. 2023;18(11):e125-e126.. PubMed PMID: 37879767.
Becich MJ. Clinical Trial Strategies Fueled by Informatics Innovation Catalyze Translational Research. JAMA Netw Open. 2023-10-02;6(10):e2336480. doi: 10.1001/jamanetworkopen.2023.36480. nihFormattedCitation: Becich MJ. Clinical Trial Strategies Fueled by Informatics Innovation Catalyze Translational Research. JAMA Netw Open. 2023;6(10):e2336480.. PubMed PMID: 37796508.
Augustin RC, Newman S, Li A, Joy M, Lyons M, Pham MP, Lucas P, Smith K, Sander C, Isett B, Davar D, Najjar YG, Zarour HM, Kirkwood JM, Luke JJ, Bao R. Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma. J Immunother Cancer. 2023-10-01;11(10): doi: 10.1136/jitc-2023-007567. nihFormattedCitation: Augustin RC, Newman S, Li A, Joy M, Lyons M, Pham MP, Lucas P, Smith K, Sander C, Isett B, Davar D, Najjar YG, Zarour HM, Kirkwood JM, Luke JJ, Bao R. Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma. J Immunother Cancer. 2023;11(10). PMCID: PMC10603348.. PubMed PMID: 37857525; PMCID: PMC10603348.
Wang H, Lu J, Stevens T, Roberts A, Mandel J, Avula R, Ma B, Wu Y, Wang J, Land CV, Finkel T, Vockley JE, Airik M, Airik R, Muzumdar R, Gong Z, Torbenson MS, Prochownik EV. Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation. Cell Rep. 2023-08-29;42(8):112830. doi: 10.1016/j.celrep.2023.112830. nihFormattedCitation: Wang H, Lu J, Stevens T, Roberts A, Mandel J, Avula R, Ma B, Wu Y, Wang J, Land CV, Finkel T, Vockley JE, Airik M, Airik R, Muzumdar R, Gong Z, Torbenson MS, Prochownik EV. Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation. Cell Rep. 2023;42(8):112830. PMCID: PMC10591215.. PubMed PMID: 37481724; PMCID: PMC10591215.
Li Z, Li T, Yates ME, Wu Y, Ferber A, Chen L, Brown DD, Carroll JS, Sikora MJ, Tseng GC, Oesterreich S, Lee AV. The EstroGene Database Reveals Diverse Temporal, Context-Dependent, and Bidirectional Estrogen Receptor Regulomes in Breast Cancer. Cancer Res. 2023-08-15;83(16):2656-2674. doi: 10.1158/0008-5472.CAN-23-0539. nihFormattedCitation: Li Z, Li T, Yates ME, Wu Y, Ferber A, Chen L, Brown DD, Carroll JS, Sikora MJ, Tseng GC, Oesterreich S, Lee AV. The EstroGene Database Reveals Diverse Temporal, Context-Dependent, and Bidirectional Estrogen Receptor Regulomes in Breast Cancer. Cancer Res. 2023;83(16):2656-2674. PMCID: PMC10527051.. PubMed PMID: 37272757; PMCID: PMC10527051.
Cole AJ, Panesso-Gómez S, Shah JS, Ebai T, Jiang Q, Gumusoglu-Acar E, Bello MG, Vlad A, Modugno F, Edwards RP, Buckanovich RJ. Quiescent Ovarian Cancer Cells Secrete Follistatin to Induce Chemotherapy Resistance in Surrounding Cells in Response to Chemotherapy. Clin Cancer Res. 2023-05-15;29(10):1969-1983. doi: 10.1158/1078-0432.CCR-22-2254. nihFormattedCitation: Cole AJ, Panesso-Gómez S, Shah JS, Ebai T, Jiang Q, Gumusoglu-Acar E, Bello MG, Vlad A, Modugno F, Edwards RP, Buckanovich RJ. Quiescent Ovarian Cancer Cells Secrete Follistatin to Induce Chemotherapy Resistance in Surrounding Cells in Response to Chemotherapy. Clin Cancer Res. 2023;29(10):1969-1983. PMCID: PMC10192102.. PubMed PMID: 36795892; PMCID: PMC10192102.
Lv D, Yang K, Rich JN. Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation. Autophagy. 2023-03-01;19(3):1034-1035. doi: 10.1080/15548627.2022.2114765. nihFormattedCitation: Lv D, Yang K, Rich JN. Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation. Autophagy. 2023;19(3):1034-1035. PMCID: PMC9980508.. PubMed PMID: 35980802; PMCID: PMC9980508.
Lee D, Gimple RC, Wu X, Prager BC, Qiu Z, Wu Q, Daggubati V, Mariappan A, Gopalakrishnan J, Sarkisian MR, Raleigh DR, Rich JN. Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling. J Clin Invest. 2023-01-17;133(2): doi: 10.1172/JCI163592. nihFormattedCitation: Lee D, Gimple RC, Wu X, Prager BC, Qiu Z, Wu Q, Daggubati V, Mariappan A, Gopalakrishnan J, Sarkisian MR, Raleigh DR, Rich JN. Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling. J Clin Invest. 2023;133(2). PMCID: PMC9843063.. PubMed PMID: 36394953; PMCID: PMC9843063.
Onkar SS, Carleton NM, Lucas PC, Bruno TC, Lee AV, Vignali DAA, Oesterreich S. The Great Immune Escape: Understanding the Divergent Immune Response in Breast Cancer Subtypes. Cancer Discov. 2023-01-09;13(1):23-40. doi: 10.1158/2159-8290.CD-22-0475. nihFormattedCitation: Onkar SS, Carleton NM, Lucas PC, Bruno TC, Lee AV, Vignali DAA, Oesterreich S. The Great Immune Escape: Understanding the Divergent Immune Response in Breast Cancer Subtypes. Cancer Discov. 2023;13(1):23-40. PMCID: PMC9833841.. PubMed PMID: 36620880; PMCID: PMC9833841.
Paniccia A, Polanco PM, Boone BA, Wald AI, McGrath K, Brand RE, Khalid A, Kubiliun N, O'Broin-Lennon AM, Park WG, Klapman J, Tharian B, Inamdar S, Fasanella K, Nasr J, Chennat J, Das R, DeWitt J, Easler JJ, Bick B, Singh H, Fairley KJ, Sarkaria S, Sawas T, Skef W, Slivka A, Tavakkoli A, Thakkar S, Kim V, Vanderveldt HD, Richardson A, Wallace MB, Brahmbhatt B, Engels M, Gabbert C, Dugum M, El-Dika S, Bhat Y, Ramrakhiani S, Bakis G, Rolshud D, Millspaugh G, Tielleman T, Schmidt C, Mansour J, Marsh W, Ongchin M, Centeno B, Monaco SE, Ohori NP, Lajara S, Thompson ED, Hruban RH, Bell PD, Smith K, Permuth JB, Vandenbussche C, Ernst W, Grupillo M, Kaya C, Hogg M, He J, Wolfgang CL, Lee KK, Zeh H, Zureikat A, Nikiforova MN, Singhi AD. Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts. Gastroenterology. 2023-01-01;164(1):117-133.e7. doi: 10.1053/j.gastro.2022.09.028. nihFormattedCitation: Paniccia A, Polanco PM, Boone BA, Wald AI, McGrath K, Brand RE, Khalid A, Kubiliun N, O'Broin-Lennon AM, Park WG, Klapman J, Tharian B, Inamdar S, Fasanella K, Nasr J, Chennat J, Das R, DeWitt J, Easler JJ, Bick B, Singh H, Fairley KJ, Sarkaria S, Sawas T, Skef W, Slivka A, Tavakkoli A, Thakkar S, Kim V, Vanderveldt HD, Richardson A, Wallace MB, Brahmbhatt B, Engels M, Gabbert C, Dugum M, El-Dika S, Bhat Y, Ramrakhiani S, Bakis G, Rolshud D, Millspaugh G, Tielleman T, Schmidt C, Mansour J, Marsh W, Ongchin M, Centeno B, Monaco SE, Ohori NP, Lajara S, Thompson ED, Hruban RH, Bell PD, Smith K, Permuth JB, Vandenbussche C, Ernst W, Grupillo M, Kaya C, Hogg M, He J, Wolfgang CL, Lee KK, Zeh H, Zureikat A, Nikiforova MN, Singhi AD. Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts. Gastroenterology. 2023;164(1):117-133.e7. PMCID: PMC9844531.. PubMed PMID: 36209796; PMCID: PMC9844531.
Atiya HI, Frisbie L, Goldfeld E, Orellana T, Donnellan N, Modugno F, Calderon M, Watkins S, Zhang R, Elishaev E, Soong TR, Vlad A, Coffman L. Endometriosis-Associated Mesenchymal Stem Cells Support Ovarian Clear Cell Carcinoma through Iron Regulation. Cancer Res. 2022-12-16;82(24):4680-4693. doi: 10.1158/0008-5472.CAN-22-1294. nihFormattedCitation: Atiya HI, Frisbie L, Goldfeld E, Orellana T, Donnellan N, Modugno F, Calderon M, Watkins S, Zhang R, Elishaev E, Soong TR, Vlad A, Coffman L. Endometriosis-Associated Mesenchymal Stem Cells Support Ovarian Clear Cell Carcinoma through Iron Regulation. Cancer Res. 2022;82(24):4680-4693. PMCID: PMC9755968.. PubMed PMID: 36219681; PMCID: PMC9755968.
Onkar SS, Carleton NM, Lucas PC, Bruno TC, Lee AV, Vignali DAA, Oesterreich S. The Great Immune Escape: Understanding the Divergent Immune Response in Breast Cancer Subtypes. Cancer Discov. 2022-12-06;OF1-OF18. doi: 10.1158/2159-8290.CD-22-0475. nihFormattedCitation: Onkar SS, Carleton NM, Lucas PC, Bruno TC, Lee AV, Vignali DAA, Oesterreich S. The Great Immune Escape: Understanding the Divergent Immune Response in Breast Cancer Subtypes. Cancer Discov. 2022;:OF1-OF18.. PubMed PMID: 36473061.
Cillo AR, Mukherjee E, Bailey NG, Onkar S, Daley J, Salgado C, Li X, Liu D, Ranganathan S, Burgess M, Sembrat J, Weiss K, Watters R, Bruno TC, Vignali DAA, Bailey KM. Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks. Clin Cancer Res. 2022-11-14;28(22):4968-4982. doi: 10.1158/1078-0432.CCR-22-1471. nihFormattedCitation: Cillo AR, Mukherjee E, Bailey NG, Onkar S, Daley J, Salgado C, Li X, Liu D, Ranganathan S, Burgess M, Sembrat J, Weiss K, Watters R, Bruno TC, Vignali DAA, Bailey KM. Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks. Clin Cancer Res. 2022;28(22):4968-4982. PMCID: PMC9669190.. PubMed PMID: 36074145; PMCID: PMC9669190.
Tao Y, Ma X, Palmer D, Schwartz R, Lu X, Osmanbeyoglu HU. Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers. Nucleic Acids Res. 2022-10-28;50(19):10869-10881. doi: 10.1093/nar/gkac881. nihFormattedCitation: Tao Y, Ma X, Palmer D, Schwartz R, Lu X, Osmanbeyoglu HU. Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers. Nucleic Acids Res. 2022;50(19):10869-10881. PMCID: PMC9638905.. PubMed PMID: 36243974; PMCID: PMC9638905.
Weiss KR, Bailey KM. A Druggable Rheostat for Ewing Sarcoma? Clin Cancer Res. 2022-10-14;28(20):4360-4362. doi: 10.1158/1078-0432.CCR-22-1794. nihFormattedCitation: Weiss KR, Bailey KM. A Druggable Rheostat for Ewing Sarcoma? Clin Cancer Res. 2022;28(20):4360-4362. PMCID: PMC9588653.. PubMed PMID: 35921177; PMCID: PMC9588653.
Gimple RC, Yang K, Halbert ME, Agnihotri S, Rich JN. Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity. Nat Rev Cancer. 2022-09-01;22(9):497-514. doi: 10.1038/s41568-022-00486-x. nihFormattedCitation: Gimple RC, Yang K, Halbert ME, Agnihotri S, Rich JN. Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity. Nat Rev Cancer. 2022;22(9):497-514.. PubMed PMID: 35710946.
Kim YS, Tang PW, Welles JE, Pan W, Javed Z, Elhaw AT, Mythreye K, Kimball SR, Hempel N. HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence. Redox Biol. 2022-07-01;53102329. doi: 10.1016/j.redox.2022.102329. nihFormattedCitation: Kim YS, Tang PW, Welles JE, Pan W, Javed Z, Elhaw AT, Mythreye K, Kimball SR, Hempel N. HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence. Redox Biol. 2022;53:102329. PMCID: PMC9121325.. PubMed PMID: 35594792; PMCID: PMC9121325.
Lv D, Gimple RC, Zhong C, Wu Q, Yang K, Prager BC, Godugu B, Qiu Z, Zhao L, Zhang G, Dixit D, Lee D, Shen JZ, Li X, Xie Q, Wang X, Agnihotri S, Rich JN. PDGF signaling inhibits mitophagy in glioblastoma stem cells through N(6)-methyladenosine. Dev Cell. 2022-06-20;57(12):1466-1481.e6. doi: 10.1016/j.devcel.2022.05.007. nihFormattedCitation: Lv D, Gimple RC, Zhong C, Wu Q, Yang K, Prager BC, Godugu B, Qiu Z, Zhao L, Zhang G, Dixit D, Lee D, Shen JZ, Li X, Xie Q, Wang X, Agnihotri S, Rich JN. PDGF signaling inhibits mitophagy in glioblastoma stem cells through N(6)-methyladenosine. Dev Cell. 2022;57(12):1466-1481.e6. PMCID: PMC9239307.. PubMed PMID: 35659339; PMCID: PMC9239307.
Labrie M, Brugge JS, Mills GB, Zervantonakis IK. Therapy resistance: opportunities created by adaptive responses to targeted therapies in cancer. Nat Rev Cancer. 2022-06-01;22(6):323-339. doi: 10.1038/s41568-022-00454-5. nihFormattedCitation: Labrie M, Brugge JS, Mills GB, Zervantonakis IK. Therapy resistance: opportunities created by adaptive responses to targeted therapies in cancer. Nat Rev Cancer. 2022;22(6):323-339. PMCID: PMC9149051.. PubMed PMID: 35264777; PMCID: PMC9149051.
Wang XS, Lee S, Zhang H, Tang G, Wang Y. An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data. Nat Commun. 2022-05-26;13(1):2936. doi: 10.1038/s41467-022-30449-7. nihFormattedCitation: Wang XS, Lee S, Zhang H, Tang G, Wang Y. An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data. Nat Commun. 2022;13(1):2936. PMCID: PMC9135729.. PubMed PMID: 35618721; PMCID: PMC9135729.
Li Z, McGinn O, Wu Y, Bahreini A, Priedigkeit NM, Ding K, Onkar S, Lampenfeld C, Sartorius CA, Miller L, Rosenzweig M, Cohen O, Wagle N, Richer JK, Muller WJ, Buluwela L, Ali S, Bruno TC, Vignali DAA, Fang Y, Zhu L, Tseng GC, Gertz J, Atkinson JM, Lee AV, Oesterreich S. ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation. Nat Commun. 2022-04-19;13(1):2011. doi: 10.1038/s41467-022-29498-9. nihFormattedCitation: Li Z, McGinn O, Wu Y, Bahreini A, Priedigkeit NM, Ding K, Onkar S, Lampenfeld C, Sartorius CA, Miller L, Rosenzweig M, Cohen O, Wagle N, Richer JK, Muller WJ, Buluwela L, Ali S, Bruno TC, Vignali DAA, Fang Y, Zhu L, Tseng GC, Gertz J, Atkinson JM, Lee AV, Oesterreich S. ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation. Nat Commun. 2022;13(1):2011. PMCID: PMC9019037.. PubMed PMID: 35440136; PMCID: PMC9019037.
Hubert CG, Rich JN. Patient-derived explants as tumor models. Cancer Cell. 2022-04-11;40(4):348-350. doi: 10.1016/j.ccell.2022.03.004. nihFormattedCitation: Hubert CG, Rich JN. Patient-derived explants as tumor models. Cancer Cell. 2022;40(4):348-350.. PubMed PMID: 35364017.
Koudelka A, Cechova V, Rojas M, Mitash N, Bondonese A, St Croix C, Ross MA, Freeman BA. Fatty acid nitroalkene reversal of established lung fibrosis. Redox Biol. 2022-04-01;50102226. doi: 10.1016/j.redox.2021.102226. nihFormattedCitation: Koudelka A, Cechova V, Rojas M, Mitash N, Bondonese A, St Croix C, Ross MA, Freeman BA. Fatty acid nitroalkene reversal of established lung fibrosis. Redox Biol. 2022;50:102226. PMCID: PMC8844680.. PubMed PMID: 35150970; PMCID: PMC8844680.
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