Selected Member Publications

NIH Citation: Levitt RC, Kandel MB, Zhuang GZ, Goins WF, Sarantopoulos KD, Glorioso JC. Biosafety and Efficacy of Kv7 Activating rdHSV-CA8* Analgesic Gene Therapy for Chronic Pain Via the Intra-Articular Route in Mice. Mol Ther. 2025;. PMCID: PMC12432987.

NIH Citation: Glorioso JC. Celebrating 25 years of Molecular Therapy. Mol Ther. 2025;. PMCID: PMC12126797.

NIH Citation: Ingusci S, Goins WF, Cohen JB, Miyagawa Y, Knipe DM, Glorioso JC. Next-Generation Replication-Defective HSV Vectors for Delivery of Large DNA Payloads. Mol Ther. 2025;. PMCID: PMC12126788.

NIH Citation: Warner BE, Shair KH. High IgG titers against EBV glycoprotein 42 correlate with lower risk of nasopharyngeal carcinoma. J Clin Invest. 2025;135(4). PMCID: PMC11827836.

NIH Citation: Warner BE, Patel J, Wang R, Adams-Haduch J, Gao YT, Koh WP, Wong KW, Chiang AKS, Yuan JM, Shair KHY. The Epstein-Barr virus nuclear antigen 1 variant associated with nasopharyngeal carcinoma defines the sequence criteria for serologic risk prediction. Clin Cancer Res. 2024;. PMCID: PMC11567791.

NIH Citation: Harioudh MK, Perez J, So L, Maheshwari M, Ebert TS, Hornung V, Savan R, Rouf Banday A, Diamond MS, Rathinam VA, Sarkar SN. The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation. Immunity. 2024;57(8):1812-1827.e7. PMCID: PMC11324410.

NIH Citation: Shang P, Dos Santos Natividade R, Taylor GM, Ray A, Welsh OL, Fiske KL, Sutherland DM, Alsteens D, Dermody TS. NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits. Cell Host Microbe. 2024;. PMCID: PMC11176008.

NIH Citation: Harioudh MK, Perez J, Chong Z, Nair S, So L, McCormick KD, Ghosh A, Shao L, Srivastava R, Soveg F, Ebert TS, Atianand MK, Hornung V, Savan R, Diamond MS, Sarkar SN. Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production. Immunity. 2024;57(3):446-461.e7. PMCID: PMC10939734.

NIH Citation: Nachega JB, Scarsi KK, Gandhi M, Scott RK, Mofenson LM, Archary M, Nachman S, Decloedt E, Geng EH, Wilson L, Rawat A, Mellors JW. Long-acting antiretrovirals and HIV treatment adherence. Lancet HIV. 2023;10(5):e332-e342. PMCID: PMC10734401.

NIH Citation: Paudel S, Warner BE, Wang R, Adams-Haduch J, Reznik AS, Dou J, Huang Y, Gao YT, Koh WP, Bäckerholm A, Yuan JM, Shair KHY. Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma. Clin Cancer Res. 2022;28(23):5221-5230. PMCID: PMC9722633.

NIH Citation: Zhang T, Zhang SW, Zhang SY, Gao SJ, Chen Y, Huang Y. m6A-express: uncovering complex and condition-specific m6A regulation of gene expression. Nucleic Acids Res. 2021;49(20):e116. PMCID: PMC8599805.

NIH Citation: Mellors JW, Guo S, Naqvi A, Brandt LD, Su L, Sun Z, Joseph KW, Demirov D, Halvas EK, Butcher D, Scott B, Hamilton A, Heil M, Karim B, Wu X, Hughes SH. Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas. Sci Adv. 2021;7(42):eabi8795. PMCID: PMC8514100.

NIH Citation: Roth AN, Aravamudhan P, Fernández de Castro I, Tenorio R, Risco C, Dermody TS. Ins and Outs of Reovirus: Vesicular Trafficking in Viral Entry and Egress. Trends Microbiol. 2021;29(4):363-375. PMCID: PMC7523517.

NIH Citation: Li T, Wang X, Ju E, da Silva SR, Chen L, Zhang X, Wei S, Gao SJ. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nat Commun. 2021;12(1):1055. PMCID: PMC7887217.

NIH Citation: Halvas EK, Joseph KW, Brandt LD, Guo S, Sobolewski MD, Jacobs JL, Tumiotto C, Bui JK, Cyktor JC, Keele BF, Morse GD, Bale MJ, Shao W, Kearney MF, Coffin JM, Rausch JW, Wu X, Hughes SH, Mellors JW. HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus. J Clin Invest. 2020;130(11):5847-5857. PMCID: PMC7598056.

NIH Citation: Bartlett DL. Better Biomarkers for Surgeons Treating Cancer. JAMA Surg. 2020;155(7):580.

NIH Citation: Kim E, Erdos G, Huang S, Kenniston TW, Balmert SC, Carey CD, Raj VS, Epperly MW, Klimstra WB, Haagmans BL, Korkmaz E, Falo LD Jr, Gambotto A. Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development. EBioMedicine. 2020;55:102743. PMCID: PMC7128973.

NIH Citation: Lentscher AJ, McCarthy MK, May NA, Davenport BJ, Montgomery SA, Raghunathan K, McAllister N, Silva LA, Morrison TE, Dermody TS. Chikungunya virus replication in skeletal muscle cells is required for disease development. J Clin Invest. 2020;130(3):1466-1478. PMCID: PMC7269570.

NIH Citation: Ge Y, Wang H, Ren J, Liu W, Chen L, Chen H, Ye J, Dai E, Ma C, Ju S, Guo ZS, Liu Z, Bartlett DL. Oncolytic vaccinia virus delivering tethered IL-12 enhances antitumor effects with improved safety. J Immunother Cancer. 2020;8(1). PMCID: PMC7103801.

NIH Citation: Ju E, Li T, Liu Z, da Silva SR, Wei S, Zhang X, Wang X, Gao SJ. Specific Inhibition of Viral MicroRNAs by Carbon Dots-Mediated Delivery of Locked Nucleic Acids for Therapy of Virus-Induced Cancer. ACS Nano. 2020;14(1):476-487. PMCID: PMC7119180.

NIH Citation: Spudich S, Robertson KR, Bosch RJ, Gandhi RT, Cyktor JC, Mar H, Macatangay BJ, Lalama CM, Rinaldo C, Collier AC, Godfrey C, Eron JJ, McMahon D, Jacobs JL, Koontz D, Hogg E, Vecchio A, Mellors JW. Persistent HIV-infected cells in cerebrospinal fluid are associated with poorer neurocognitive performance. J Clin Invest. 2019;129(8):3339-3346. PMCID: PMC6668666.

NIH Citation: Li T, Ju E, Gao SJ. Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. J Clin Invest. 2019;129(8):3310-3323. PMCID: PMC6668677.

NIH Citation: Ghosh A, Shao L, Sampath P, Zhao B, Patel NV, Zhu J, Behl B, Parise RA, Beumer JH, O'Sullivan RJ, DeLuca NA, Thorne SH, Rathinam VAK, Li P, Sarkar SN. Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production. Immunity. 2019;50(1):51-63.e5. PMCID: PMC6342484.

NIH Citation: Guo ZS, Lu B, Guo Z, Giehl E, Feist M, Dai E, Liu W, Storkus WJ, He Y, Liu Z, Bartlett DL. Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics. J Immunother Cancer. 2019;7(1):6. PMCID: PMC6325819.

NIH Citation: Liu Z, Ge Y, Wang H, Ma C, Feist M, Ju S, Guo ZS, Bartlett DL. Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nat Commun. 2018;9(1):4682. PMCID: PMC6224581.