Investigators

Summary

My research as a neurosurgeon-scientist has focused on the translation of new therapies and intraoperative visualization of glioblastoma (GBM). I direct the Brain Tumor Nanotechnology Laboratory in the Hillman Cancer Center studying the use of magnetic iron-oxide nanoparticles (MIONPs) for the targeted imaging and magnetic hyperthermia therapy (MHT) of GBM after convection-enhanced delivery (CED). This collaborative and translational NIH- funded research involves Johns Hopkins University and Penn State University developing a new treatment for GBM. My research is also focused on the study of fluorescence-guided surgery (FGS) and photodynamic therapy (PDT) of GBM. My team was the first to use Gleolan (5-ALA) and perform FGS on a GBM patient in the US in 2011. We also led the FDA effort for approval of 5-ALA (Gleolan) in the US in June 2017.