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Hua Zhang

Hua Zhang

Program: Cancer Therapeutics

(412) 864-7742 zhangh18@upmc.edu Hillman Cancer Center Research Pavilion
5117 Centre Ave, Suite 2.42d
Pittsburgh PA
Summary

The main research focuses of my lab are:
1. establishing new immunocompetent mouse models for lung cancer and utilizing them to study the therapeutic efficacy and mechanisms of novel combination of targeted therapy with immunotherapy
2. identifying new therapeutic vulnerabilities to overcome drug resistance in lung cancer
3. characterizing the organ-specific tumor immune contexture to develop immunotherapeutic strategies.
4. targeted degradation of KRAS mutants using in vivo PROTAC system. 

Research Interests and Keywords
  • Antitumor Immunity
  • CDK7
  • Immunotherapy
  • Lung Cancer
  • Mouse Modeling
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