Find a Member

Full Investigator List

Finding the right member is just a click away.

Lawrence Kane

Lawrence Kane

Program: Cancer Immunology and Immunotherapy

412-383-6880 E-1054 BSTWR
200 Lothrop St.
Pittsburgh PA

My lab is focused on the study of signal transduction pathways that regulate antigen-dependent activation of T cells and mast cells. Toward that end, we are engaged in several specific projects: 1. Understanding the signaling pathways downstream of Carma1, MALT1 and Bcl10 (CBM complex) in T cells 2. Defining biochemical and spatial regulation of NF-kB activation by the TCR/CD3 complex, along with CD28 co-stimulation 3. Understanding signal transduction pathways downstream of the transmembrane proteins Tim-1 and Tim-3, in T cells and mast cells

Research Interests and Keywords
  • co-stimulation
  • Immunology
  • kinases
  • Mast Cells
  • Signal Transduction
  • T cells
Read More about Lawrence Kane

View Investigators by Last Name

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z