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An NCI-designated Comprehensive Cancer Center, affiliated with the University of Pittsburgh School of Medicine
Research
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The Sheikh lab is interested in understanding how various oncogenic drivers impact the response to DNA damage agents in pediatric CNS malignancies. Furthermore, we seek to determine how the alterations in the metabolome of pediatric CNS malignancies impact the response to DNA damage agents. Our ultimate goal is identify novel synergistic therapies that enhance the cell death response of pediatric brain tumors to DNA damage.
