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Radiation and Oxidative Damage investigators

Christopher Bakkenist

Christopher Bakkenist

bakkenistcj@upmc.edu The Assembly
5051 Centre Ave
Pittsburgh PA
Research Interests and Keywords
  • Cancer pharmacology
  • DNA repair
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Hulya Bayir

Hulya Bayir

(412) 692-5164 Bayihx@upmc.edu UPMC Children's Hospital of Pittsburgh
4401 Penn Ave.
Pittsbrugh PA
Research Interests and Keywords
  • Lipid signaling and lipid imaging in cell death and inflammation; Mitochondrial injury and mitochondria - targeted therapies; Redox biomedicine
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Kara Bernstein

Kara Bernstein

412-864-7742 karab@pitt.edu 5117 Centre Avenue
Hillman Cancer Center Research Pavilion 2.42
Pittsburgh PA
Summary

My work is to determine what genetic factors make some people more likely to develop cancer, particularly breast and ovarian cancers. The genes that we study are important for fixing damage to DNA. If these genes are not operating properly and DNA damage is uncorrected, cancer may develop. DNA damage can be caused by our bodies themselves or from outside sources such as chemicals found in the environment. We are working to better predict who is likely to get cancer by understanding both people's genes and their environmental exposures. By doing so, we aim to create new tailored strategies for treating people's tumors and ultimately prevent patients from developing breast and ovarian cancers at all.

 

Research Interests and Keywords
  • DNA repair, DNA recombination, DNA replication, double-strand break repair, Shu complex, Rad51 paralogs, breast and ovarian cancers
Read More about Kara Bernstein
Marcel Bruchez

Marcel Bruchez

bruchez@cmu.edu Mellon Institute 294A
Pittsburgh PA
Research Interests and Keywords
  • Fluorescence
  • biological microscopy
  • imaging
  • light-harvesting structures
  • biosensors
  • single molecule biophysics
  • protein translation
  • protein folding
  • protein trafficking
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Joel Greenberger

Joel Greenberger

412-647-3602 greenbergerjs@upmc.edu UPMC Shadyside Radiation Oncology
UPMC Cancer Pavilion, POB2, Rm. 533 5150 Centre Avenue
Pittsburgh PA
Summary

Dr. Greenberger is examining the use of manganese superoxide dismutase (MnSOD) plasmid liposome gene therapy and GS-nitroxides, as agents to protect the normal tissues in the esophagus and lung from damage during radiation therapy. Damage to normal tissues during radiation therapy has been a major limitation to the effective treatment of lung cancer. The goal of his research is to improve the quality of life for cancer patients by potentially allowing the use of higher doses of radiation or chemotherapy to effectively treat lung cancer without the damaging side effects.

Research Interests and Keywords
  • Radiation mitigator
  • radiation protection
  • lung cancer
Read More about Joel Greenberger
Patricia Opresko

Patricia Opresko

412-623-7764 plo4@pitt.edu UPMC Hillman Cancer Center Research Pavilion
5117 Centre Avenue, Suite 2.6a
Pittsburgh PA
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Roderick O'Sullivan

Roderick O'Sullivan

osullivanr@upmc.edu Hillman Cancer Center
5117 Centre Avenue Suite 2.6d
Pittsburgh PA
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Heath Skinner

Heath Skinner

412-623-3275 skinnerh@upmc.edu UPMC Hillman Cancer Center, Research Pavilion
Suite 2.6a, 5117 Centre Ave.
Pittsburgh PA
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Donna Stolz

Donna Stolz

412-383-7283 dstolz@pitt.edu S221 BST-South
Pittsburgh PA
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Bennett Van Houten

Bennett Van Houten

vanhoutenb@upmc.edu Hillman Cancer Center
5117 Centre Avenue Lab 2.6e
Pittsburgh PA
Research Interests and Keywords
  • DNA repair
  • cancer pharmacology
  • drug discovery
Read More about Bennett Van Houten
Hong Wang

Hong Wang

how8@pitt.edu 130 De Soto Street
Pittsburgh PA
Research Interests and Keywords
  • Survival analysis and statistics in cancer biomarker research
  • radiation survival analysis
Read More about Hong Wang
Simon Watkins

Simon Watkins

swatkins@pitt.edu S225 BST-South
Pittsburgh PA
Research Interests and Keywords
  • Cellular organization
  • cell-cell communications
  • cell imaging
Read More about Simon Watkins

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