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Conduct Early-Phase (I/II) Clinical Trials investigators

Leonard Appleman

Leonard Appleman

Program: Cancer Therapeutics

412-648-6507 applemanlj@upmc.edu UPMC Cancer Pavilion
5230 Center Ave., Suite 567
Pittsburgh PA
Research Interests and Keywords
  • experimental cancer therapeutics,Kidney cancer and other genitourinary malignancies
Read More about Leonard Appleman
Jan Beumer

Jan Beumer

Program: Cancer Therapeutics

412-623-3216 beumerjh@upmc.edu G27E Hillman Cancer Center
5117 Centre Avenue
Pittsburgh PA
Research Interests and Keywords
  • nucleoside analogues and epigenetic drugs,Pharmacokinetics and metabolism of anti-cancer drugs
Read More about Jan Beumer
Alberto Broniscer

Alberto Broniscer

Program: Cancer Therapeutics

Read More about Alberto Broniscer
Adam Brufsky

Adam Brufsky

Program: Cancer Therapeutics

brufskyam@upmc.edu 300 Halket St
Suite 4628
Pittsburgh PA
Research Interests and Keywords
  • Breast Cancer,Clinical Trials,molecular biology of breast cancer
Read More about Adam Brufsky
Melissa Burgess

Melissa Burgess

Program: Cancer Therapeutics

burgessma@upmc.edu UPMC Cancer Pavilion
5150 Centre Ave.
Pittsburgh PA
Summary

My research is focused on clinical and translational studies of soft tissue and bone sarcomas. Currently, I am investigating an immunotherapy utilizing an anti-PD1 inhibitor for patients with advanced sarcomas. In the future, I plan to further study novel immunotherapeutic approaches for advanced sarcomas, particularly with combinatorial strategies.

Research Interests and Keywords
  • clinical and translational research,Immunotherapy,Medical Oncology,Sarcoma
Read More about Melissa Burgess
Lan Coffman

Lan Coffman

Program: Cancer Biology

412-641-2016 coffmanl@mail.magee.edu The Assembly
5051 Centre Ave
Pittsburgh PA
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Kathleen Dorritie

Kathleen Dorritie

Program: Cancer Therapeutics

Read More about Kathleen Dorritie
Jan Drappatz

Jan Drappatz

Program: Cancer Therapeutics

drappatzj@upmc.edu UPMC Cancer Pavilion
5150 Center Ave
Pittsburgh PA
Summary

My research is directed towards the development of new therapies for primary and secondary brain tumors using targeted drugs, inhibitors of angiogenesis, and immunotherapies. I am also interested in the identification of molecular markers of prognosis in patients with malignant glioma and other primary brain tumors.

Research Interests and Keywords
  • Angiogenesis Inhibitors,brain tumors,CNS tumors,Glioblastoma,Glioma,Immunotherapy,neurologic complications of cancer,prognostic biomarkers,targeted therapies
Read More about Jan Drappatz
Umamaheswar Duvvuri

Umamaheswar Duvvuri

Program: Cancer Therapeutics

duvvuriu@upmc.edu Eye and Ear Institute, Suite 300
203 Lothrop Street
Pittsburgh PA
Research Interests and Keywords
  • Otolaryngology,translational science of head and neck cancer
Read More about Umamaheswar Duvvuri
Annie Im

Annie Im

Program: Cancer Therapeutics

imap@upmc.edu Cancer Pavilion, Rm 554
5150 Centre Ave.
Pittsburgh PA
Summary

1) Acute myeloid leukemia (AML) in elderly patients: My research focuses on epigenetic strategies in the treatment of older patients with AML. We are running a clinical trial of a novel induction regimen using epigenetic priming by decitabine followed by cytarabine in older patients with newly diagnosed AML. Epigenetic correlatives studies are planned. 2) Epigenetic strategies to prevent relapse after hematopoietic stem cell transplant: I am interested in the role of epigenetic agents as immunomodulatory therapy to prevent relapse and graft-versus-host disease in patients with AML or MDS who are at high risk for relapse after allogeneic stem cell transplant. We are running a clinical trial using azacitidine maintenance therapy after allogeneic transplant for patients with AML and MDS. Correlative studies evaluating immune reconstitution and T-cell populations are planned. 3) Chronic graft-versus host disease (GVHD): I am interested in the study of chronic GVHD and long-term follow-up of allogeneic stem cell transplant patients. I work in collaboration with the Experimental Transplantation and Immunology Branch of the National Cancer Institute in the area of chronic GVHD. I study the natural history of chronic GVHD, as well as chronic GVHD-specific complications such as bronchiolitis obliterans syndrome.

Research Interests and Keywords
  • Acute Myeloid Leukemia (AML),bronchiolitis obliterans syndrome,chronic graft-versus-host disease (GVHD),Epigenetics,Hematopoietic Stem Cell Transplantation,hypomethylating agents
Read More about Annie Im
Seungwon Kim

Seungwon Kim

Program: Cancer Therapeutics

kimsw2@upmc.edu 200 Lothrop Street
EEI, Suite 500
Pittsburgh PA
Research Interests and Keywords
  • head and neck neoplasms ,Squamous cell carcinoma
Read More about Seungwon Kim
Frank Lieberman

Frank Lieberman

Program: Cancer Therapeutics

liebermanf@upmc.edu Department of Neurology
811 Kaufmann Medical Building 3471 Fifth Avenue
Pittsburgh PA
Research Interests and Keywords
  • and management of CNS neoplasms,molecular genetics and molecular neuropathology in diagnosis,neuro-oncology,Prognosis
Read More about Frank Lieberman
Yan Lin

Yan Lin

Program: Cancer Therapeutics

yal14@pitt.edu 130 De Soto Street
Pittsburgh PA
Research Interests and Keywords
  • Cancer bioinformatics
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Priscilla McAuliffe

Priscilla McAuliffe

Program: Cancer Therapeutics

mcauliffepf@mwri.magee.edu 204 Craft Avenue
Pittsburgh PA
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Alexander Olawaiye

Alexander Olawaiye

Program: Cancer Therapeutics

Read More about Alexander Olawaiye
Priya Rastogi

Priya Rastogi

Program: Cancer Therapeutics

rastogip@upmc.edu UPMC CancerCenter at Magee-Womens Hospital of UPMC
300 Halket Street
Pittsburgh PA
Research Interests and Keywords
  • Breast Cancer,Medical Oncology
Read More about Priya Rastogi
Robert Redner

Robert Redner

Program: Cancer Therapeutics

redner@pitt.edu 2.18A Hillman Research Pavilion
5117 Centre Avenue
Pittsburgh PA
Research Interests and Keywords
  • Acute Myeloid Leukemia,Acute promyelocytic leukemia,malignant and non-malignant hematology ,Myelodysplastic Syndromes
Read More about Robert Redner
D Lansing Taylor

D Lansing Taylor

Program: Cancer Therapeutics

dltaylor@pitt.edu 10045 Biomedical Science Tower 3
3501 Fifth Avenue
Pittsburgh PA
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Sarah Taylor

Sarah Taylor

Program: Cancer Therapeutics

(412) 641-5468 taylorse2@mail.magee.edu Magee-Womens Hospital of UPMC
300 Halket Street
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Liza Villaruz

Liza Villaruz

Program: Cancer Therapeutics

villaruzl@upmc.edu UPMC Cancer Pavilion
5150 Centre Avenue 5th Floor
Pittsburgh PA
Research Interests and Keywords
  • Clinical trials in lung cancer,novel therapeutics
Read More about Liza Villaruz
Norman Wolmark

Norman Wolmark

Program: Cancer Therapeutics

Read More about Norman Wolmark

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