Program Members

Summary

I am a behavioral scientist with a research focus on understanding and addressing cancer health disparities. My clinical training as a psychologist and extensive NIH-funded research history includes the design, evaluation and dissemination of behavioral and environmental interventions to address cancer and other chronic conditions. My approach relies heavily on community-based participatory research (CBPR) to identify sociocultural and environmental determinants of health among populations at greater risk of disease (e.g., African Americans, lower income populations, rural residents). For example, I served as PI for the Full Research Project on a community network partnership center grant (U54CA153719) that involved a cluster-randomized trial of a multi-level weight loss intervention for African American women at higher risk of cancer who live in the rural Deep South (Alabama and Mississippi) and a cluster-randomized trial testing the efficacy of a weight loss intervention for African American cancer survivors in the Black Belt of Alabama (R01CA160313). My collective work has cemented my expertise in outreach and engagement, the recruitment and retention of underrepresented groups into biobehavioral research, recruitment of family and non-family support, community-engaged research, mixed-method designs, and dissemination of research findings to multiple audiences (including participants and community partners). I believe membership in the HCC research program will afford me greater access to collaborations and resources to expand my work and adapt research originally conducted in the Deep South to populations in Pennsylvania.

Summary

Currently I work in cancer surveillance via survey methods to investigate factors related to disparities in cancer prevention, access to treatment, quality of life, and cancer-related protective and risk factors across the lifespan. As the Director of the HCC’s Population Survey Facility, I envision collaborations with HCC members that will ultimately result in interdisciplinary work through a population health lens focusing specifically on reducing cancer related health disparities in the HCC catchment area.

Summary

Dr. Belcher’s research focuses on understanding and improving health outcomes among patients with cancer, particularly among patients with high cost and advanced cancers and among socioeconomically disadvantaged and historically excluded populations.
 
Her career development award is investigating how adherence to oral anticancer medication affects pain and quality of life and how financial hardship influences these relationships over time among patients with multiple myeloma. Her prior research identified predictors of poor health outcomes among adults with multiple primary cancers and relationships between financial hardship and quality of life among patients with advanced and high symptom burden cancers. 

Summary

My two areas of research interest include the neuropsychological sequellae of cancer and cancer treatment and the physiological mechanisms underlying these problems and adherence to cancer therapy. More specifically, my research focuses on the changes in cognitive function and mood that occur in patients with cancer. I also examine whether the changes in reproductive hormones that occur as a consequence of cancer therapy are related to changes in cognitive function experienced by women with cancer, and we are investigating candidate genes for correlations with cognitive function in patients with cancer. I also study adherence to therapy in patients with cancer and other chronic conditions and predictors of non-adherence to therapy.

Summary

Interdisciplinary studies of: biobehavioral factors in cancer; the emotional, cognitive, behavioral, and biological consequences of breast cancer risk; the contribution of biobehavioral factors to side effects of medical treatments (surgery, chemotherapy, radiotherapy) and interventions that may ameliorate those effects; interactions between psychological and genetic factors in persistent smoking behavior; and, psychological influences on cancer screening decisions.

Summary

The mission of my research is to improve pain management and quality of life for patients with cancer. am currently funded by the Pitt CTSI KL2 to explore stigma around prescription opioids in adults with advanced cancer, who often have high rates of moderate-to-severe pain and prescription opioid exposure. The second aim of my work is to identify patients at risk for cancer-related pain and neuropathy as early as possible in order to improve access to effective pain management resources. In addition to my own research, I collaborate closely with my mentors Dr. Yael Schenker and Dr. Jessica Merlin, as well as other collaborators across the university, on other relevant projects. For example, I serve as co-I and site PI for a recently funded R01 (PI: Merlin) to understand risks, benefits, and stakeholder perspectives of opioid prescribing for patients with advanced cancer who are expected to live for years with their diagnosis.

Summary

My long-term goal is to develop a program of research focused on preventing tobacco-related cancer mortalities. I have a diverse background in computer science, social network analysis, online social media, and cancer prevention. The focus of my research has been leveraging innovative technologies to study tobacco control. My recent projects include exploring the presence of tobacco companies on social media and analyzing their behavior and strategies in marketing; studying the diffusion of anti-vaccination topics online; interventions for electronic cigarette use by adolescents; modeling new tobacco trends to inform regulatory agencies.

Summary

Dr. Conley’s research interests are in the field of molecular genetics. She has a fully equipped molecular genomics laboratory located within the School of Nursing, and her lab is involved with several research projects. Her current research focuses on genomic and epigenomic studies of patient outcomes after traumatic brain injury, stroke, and therapeutic interventions for cancer, as well as genomic studies of age-related macular degeneration.

Summary

Pathological changes in sensory neurons is thought to contribute to chronic pain associated with fibromyalgia, neuropathic pain, irritable bowel syndrome (IBS), pancreatitis, gastroesophageal reflux disease (GERD) and cancer. In addition to producing debilitating pain sensations, hyperactive sensory neurons can release bioactive peptides that further exacerbate disease. Research in the Davis laboratory focuses on the role of growth factors in the development and adult plasticity of the central and peripheral nervous system. This work is being conducted in collaboration with Dr. Kathryn Albers (Department of Medicine), who has created lines of transgenic mice overexpressing specific growth factors; and Dr. H. Richard Koerber (Department of Neurobiology), who is examining plasticity of second-order spinal cord neurons. Currently, Dr. Davis's research is focused on somatic and visceral pain and growth factors of the NGF and GDNF families. Specifically, he has found that these growth factors (that are required for embryonic development of primary afferents) are upregulated in models of chronic pain. The lab also has strong evidence that this upregulation directly contributes to the development of persistent pain states. The goal of this research is to determine how these changes contribute to the development of chronic pain, with an emphasis on the transcriptional events and downstream signaling that controls the response properties of sensory neurons. This information may lead to identification of new targets that could be the basis of novel therapies for chronic somatic and visceral pain.

Summary

I investigate longitudinal patterns of drug use and reproductive health in pregnant and parenting people. I take a developmental approach, meaning that I am interested in the timing of behavior within the context of important life events such as puberty, adolescence, young adulthood, pregnancy, and menopause. I am also interested in better understanding health-risk behaviors within the context of families, systems, and communities, including the impact of pervasive structural racism and discrimination, sexism, and heterosexism. 

Summary

Dr. Donovan’s research interests are in the development and testing of  interventions to improve symptoms and quality of life among individuals with cancer and their family caregivers (NINR R01NR010735; NR01370; 90RTGE0002). She has specific expertise in the integration of theory and evidence to design and test e-health interventions to improve self-management for families facing chronic and life threatening illnesses and disabilities. Her work has been grounded in the Representational Approach (RA) to patient education, an intervention theory that she co-developed. The RA has been used to guide a wide range of interventions in cancer symptom management, family caregiving, heart failure, end stage renal disease and palliative care. Currently, she is the corresponding PI and co-Director of the National Rehabilitation Research and Training Center on Family Support (NCFS; 90RTGE0002; www.caregiving.pitt.edu). NCFS’ mission is to partner with government, academia, and the broad family support stakeholder community to translate state-of-the-art research and training into services and support programs to improve the care, health, and quality of life of all persons with disabilities and the families who support them. Her current research within NCFS is focused on integrating family caregiver assessments and interventions into an established platform to be relevant to caregivers across a wide range of care recipient illnesses and disabilities.

Summary

Dr. Ferguson is a licensed clinician psychologist and assistant professor of medicine in the Division of Hematology/Oncology. His clinical and research interests are in cancer survivorship and cognitive-behavioral treatment of cancer-related cognitive impairment. 

Summary

Kaposi's sarcoma-associated herpesvirus (KSHV), or HHV-8, is a member of the human herpesvirus family whose DNA sequences have been found in samples of Kaposi's sarcoma (KS). A number of projects in our laboratory are focused on the prevalence of KSHV infection in various cohorts and populations. We are particularly interested in the serological association of KSHV with human prostate cancer and are investigating at a molecular level, potential roles for KSHV in progression and maintenance of this cancer. We are also exploring the events during primary KSHV infection, including interactions between the virus and cell membrane, modulation of host gene synthesis, and establishment of viral infection. My lab has also been involved for several years in biobehavioral medicine. Specifically, we are interested in the role of stress and stress hormones in disease pathogenesis. Our current studies involve how stress hormones affect individual cells, the types of damage they may inflict on these cells and the outcomes of these interactions.

Summary

My research interests have been focused on structuring and delivering health information through an informatics-based approach to diverse groups, especially to minority populations. Especially, my research has engaged community residents to assess their needs and understand their circumstances in order to empower them to manage their own health through health communication interventions. Methodologically, I have extensive experience in mining big data to reveal hidden relationships between agents. 

My current project is to apply network analysis to social media data to understand patterns of symptom cluster and unmet needs among ovarian cancer survivors. 

Summary

Michele D. Levine, PhD, a licensed clinical and health psychologist, is Professor of Psychiatry, Psychology and Obstetrics, Gynecology and Reproductive Sciences at the University of Pittsburgh. Dr. Levine’s program of research focuses on relationships among health behaviors and mental health during pregnancy and the postpartum period. Dr. Levine also directs a T32 postdoctoral training grant and an affiliated clinical psychology internship training program at Western Psychiatric Hospital, both of which support clinical research training.

Summary

Dr. Low is a clinical health psychologist focused on using consumer mobile technology including wearable devices and smartphones for remote monitoring of symptoms and functioning during cancer treatment. Her team is interested in using these real-world data to predict clinical outcomes, to support patient self-management and patient-provider communication, and to personalize behavioral interventions aimed at optimizing quality of life.

Summary

I am a Tenured Professor of Medicine at the University of Pittsburgh, the director of Pitt's CHAllenges in Management and Prevention of Pain (CHAMPP) center, and the PI of a NIDA-funded research center, Tailored Retention and Engagement for Equitable Treatment of OUD and Pain (TREETOP), the goal of which is to improve treatment for comorbid opioid use disorder (OUD) and chronic pain. I am a PhD-trained behavioral scientist and an addiction medicine and palliative care physician who treats individuals with opioid misuse/OUD and chronic pain, including chronic cancer-related chronic pain. I have expertise in medical cannabis and have published 5 peer-reviewed paper related to cannabis policy and the use of cannabis among patients with cancer. I and my team recently published a paper in JAMA Oncology on developing consensus among palliative care and addiction specialists on the appropriateness of various opioid management strategies in individuals with advanced cancer-related pain and opioid misuse or OUD. I have also received an NIH-funded K24 grant, entitled "Mentoring the next generation of researchers at the intersection of opioid use disorder and chronic pain," which will not only assist in the mentorship of a new cadre of professionals, but proposes a new research project that leverages existing Delphi-based preliminary data to develop an implementation strategy bundle to promote the adoption and equitable application of evidence-based approaches for managing opioid misuse/OUD and metastatic cancer-related pain.

Summary

Dr. Nilsen's research interests include: 1. Impact of communication and interaction behaviors on nursing care quality of acutely ill older adults; 2. Acceptance and adoption of alternative communication tools to improve symptom management for older adults recovering from surgery for head and neck cancer; and 3. Survivorship and late effects of treatment for head and neck cancer.

Summary

Research in the Orwig laboratory focuses on stem cells, germ lineage development, fertility, and infertility. Our progress investigating reproductive function in fertile individuals provides a basis for understanding the mechanisms of infertility caused by disease, medical treatments, genetic defects, or aging.  Infertility impacts one in seven couples in the United States and can have a devastating impact on relationships and emotional well-being.  The Orwig lab is ideally located in Magee-Womens Research Institute and Magee-Womens Hospital and is committed to translating lab bench discoveries to the clinic for diagnosis, prevention, and treatment of infertility. 

Summary

Dr. Perkins has been continually funded by NIH since 1986 to conduct research focused largely on two broad “themes”. One emphasizes translational studies, drawing on preclinical findings to examine acute effects of nicotine (and cigarette smoking) that may explain persistence of tobacco dependence in humans. That work was recognized in 2020 by American Psychological Assoc’s (APA) Med-Associates Brady-Schuster Award for outstanding behavioral research in psychopharmacology or substance abuse. The second theme aims to improve clinical treatments for smoking cessation. His recent focus has been on development, validation, and extension of an efficient crossover study design procedure to evaluate whether new medications are, or are not, efficacious for helping smokers quit, thereby informing subsequent large and formal randomized trials to confirm such efficacy. Relatedly, he co-authored a smoking cessation treatment guide for health care providers, “Cognitive-behavioral therapy for smoking cessation: a practical guide to the most effective treatments.”  For this work, he was named by the Society for Research on Nicotine and Tobacco (SRNT) as 2022 recipient of the triennial Ove Ferno award for groundbreaking advances in clinical research on nicotine and tobacco use. Today, Dr. Perkins is author of nearly 300 publications, with a citation index (h) above 75 and nearly 20,000 total citations.  He was also elected SRNT president in 2001 and a Fellow of APA, SRNT, and the Society of Behavioral Medicine (SBM).  Finally, he has contributed to the missions of the Univ of Pittsburgh medical school and Psychology department by teaching and mentoring graduate students and medical students. 

Summary

I have conducted behavioral research in a variety of cancer populations including breast, gynecologic, head and neck, and hematological malignancies. I currently hold an NCI K23 Career Development Award examining adherence to the medical regimen for hematological cancer patients who are post allogeneic hematopoietic cell transplantation (HCT) and their family caregivers. Allogeneic HCT is a potentially curative therapy for hematologic disease, but is associated with multiple complications and significant stress to patients and family caregivers (CGs). To enhance outcomes and minimize risks, patients and CGs must work together as a team to carefully adhere to the multi-component post-HCT medical regimen, consisting of multiple daily medications, frequent clinic visits, strict catheter care, health monitoring, and dietary and lifestyle restrictions. Despite the clinical importance of adherence to the post-HCT regimen, particularly during the critical first 100 days post HCT, little research has examined rates or risk factors for nonadherence in this population, or how HCT patients and family caregivers manage each component of the post-HCT regimen together. Further, it is important to develop strategies to help patients and family caregivers better adhere to the regimen. Problem-Solving Therapy (PST), an evidenced-based clinical intervention to enhance coping strategies, will be the basis to build a novel patient-caregiver dyadic intervention for the HCT population.

Summary

Our team’s research is focused on the factors that ensure that all women with breast cancer receive timely diagnoses, treatment, and support. Our research, education, and outreach initiatives are directed toward Black women with breast cancer, women with metastatic breast cancer, and community engagement to address racial and economic breast cancer survival disparity.  Our team is well-published, with over 130 publications and multiple national and international presentations disseminating the results of our research. The Symptom Experience, Management, and Outcomes According to Race and Social Determinants of Health during Breast Cancer Chemotherapy (SEMOARS) study is a multi-site R01-funded study comparing the symptom incidence and distress, symptom reporting methods and outcomes, including the ability to receive the full dose of prescribed chemotherapy between Black and White women as they proceed through chemotherapy. Genetics, epigenetics, and pharmacogenomics are areas of further exploration..Our Ubuntu Pittsburgh Project (UPP) (Pittsburgh Foundation)  for Black women with metastatic breast cancer living in the Pittsburgh Area has offered support, legacy building, and family support to women and their families. We are currently pilot-testing this program in the Pittsburgh area. 

With the support of the Genentech Health Equity Grant (2020-2022), we led an initiative in cancer as a canvas for all researchers to collaborate in basic and behavioral research to better understand the influence of neighborhood deprivation, discrimination, and lifetime allostasis, measured through telomere length, allostatic load, and immune markers on cancer outcomes. This initiative, Exploring Allostasis, Cellular Aging, and Cancer Outcomes, was renewed for an additional three years (2023- 2025) and is now incorporating all regional patients with cancers in which survival disparities are present.

In collaboration with Magee Womens Hospital, our team leads the Support, Education, and Advocacy Program for Women with Metastatic Breast Cancer (MBC/SEA Program). We developed and maintained a database of 2,000 women with metastatic breast cancer. These findings informed the development of a successful nurse-led primary palliative care intervention for all patients with metastatic breast cancer seen at Magee Women's Hospital. We are partners and leaders in the  Allegheny County Breast Cancer Equity Project, a community outreach program that seeks to assist women in underserved communities to access existing breast cancer resources. In response to local data, plans are to utilize students from the School of Public Health and senior-level student nurses to offer education and support in a structured Community Health clinical.

Summary

Dr. Sabik is a health economist and health services researcher focused on investigating the role of state and federal policies in affecting healthcare access, utilization, and health outcomes among low-income populations, with a particular focus on cancer care for underserved populations. She is currently principal investigator on a project funded by the National Cancer Institute investigating the role of Medicaid policy in breast and cervical cancer screening for low-income women and disparities in screening and outcomes. In addition, she is PI on a Research Scholar Grant from the American Cancer Society to study the impact of state health reform on breast and colorectal cancer diagnosis and treatment. She has also served as an investigator on a number of foundation-funded projects evaluating Medicaid policies and programs at the state and national levels and investigating issues related to the role of the healthcare safety net.

Summary

The Saloman lab focuses on how peripheral nerves shape the incipient tumor microenvironment. Current studies are designed to understand how sensory and sympathetic nerves regulate anti-tumor immunity and cancer pain. Several immune checkpoint proteins are expressed by the neurons that innervate the pancreas and ongoing experiments are investigating the role of these signaling molecules in regulation of the tumor microenvironment. Our overall goal is to understand the role of neural circuits to cancer biology and to harness this knowledge to improve early detection as well as identify targets for novel therapeutic approaches. 

Summary

Dr. Sayette's research focuses on psychological theories of alcohol use and abuse, cigarette smoking, and drug craving, and on cognitive, affective, and social processes in addiction.

Summary

Head and neck squamous cell carcinoma (HNSCC) causes severe pain and stress, which exceeds the levels seen in other cancers. Beyond sensory/pain signaling, the peripheral nervous system has been identified as a component of the cancer microenvironment and may be involved in modulating tumor progression and tumor-associated immunity. The cancer microenvironment is comprised of stromal cells, glial cells, immune cells, neurons (e.g., motor, sensory, sympathetic) and proliferating tumor cells. The Scheff lab seeks to integrate the neurobiology, cancer biology, and immunology fields to fully appreciate neural-immune-cancer communication. The goal of our research is to understand plasticity in peripheral neurons associated with head and neck cancer and to investigate whether therapy targeted to neurons in the cancer microenvironment can alleviate pain and improve anti-tumor immunity. The lab executes translational research through collection of patient-reported outcomes and clinical specimens as well as implementation of molecular, electrophysiological and behavioral studies in preclinical mouse models.

Summary

My primary research interest is in the integration of palliative care services in oncology, with a particular focus on developing new models to improve provision of 'primary' palliative care within oncology practices. Secondary research interests include goals of care discussions, quality of life, healthcare policy in serious illness, surrogate decision making, informed consent, and the impact of language and cultural barriers on patient-clinician communication. 

Summary

I am an exercise oncology researcher. My work focuses on large clinical trials related to physical activity and cancer, across the cancer control continuum, from primary prevention to addressing the needs of advanced cancer patients. The central mission of my work is to make exercise standard of care in oncology. Therefore, in addition to the efficacy trials my lab conducts, I am also actively involved in national and international efforts related to implementation of exercise for people living with and beyond cancer. UPMC Hillman Cancer Center is a vibrant community of science with an enormous network, which forms a tremendous platform from which to conduct both efficacy and implementation trials. The spirit of entrepreneurism at HCC allows innovation in keeping with my central mission. I currently lead 3 large NIH funded trials ranging from primary prevention to advanced cancer patients, all with an exercise oncology focus. In my role as leader of the exercise oncology initiative, my goal is to partner with the clinicians of HCC to discern the best ways to ensure that all cancer patients are informed about the benefits of exercise, supported to become active, and referred to appropriate resources (to include outpatient rehabilitation).  

My work has appeared in JAMA, New England Journal of Medicine, JAMA Oncology, JNCI, and JCO, among other prestigious journals. I am the lead author on the first exercise guidelines for cancer patients and survivors from 2010, and senior author on the update from 2019.  I have won numerous prestigious scientific awards, among them the Citation Award from the American College of Sports Medicine and the Distinguished Scientist Award from the Society of Behavioral Medicine. 

Summary

I am a PhD-prepared biostatistician and have collaborated with cancer researchers, primarily in the University of Pittsburgh School of Nursing, for more than 25 years in the area of behavioral and biomedical science, particularly symptom science and the possible toxic effects of cancer treatments and their impact on adherence to cancer treatments.

Summary

Dr. Shadel's research ranges from basic human laboratory work designed to understand the biopsychosocial mechanisms that contribute to smoking initiation and cessation, to the evaluation of cognitive-behavioral and pharmacological smoking cessation interventions in the clinic and public health settings. He has been continuously funded as a principal investigator by the National Cancer Institute and National Institute on Drug Abuse since 1999. Dr. Shadel's current grants examine how tobacco advertising contributes to adolescent smoking behavior, and the psychosocial mechanisms that underlie relapse in adult smokers.

Summary

My primary research focus is on biobehavioral interactions in persons with cancer and neurologic conditions. I am particularly interested in the area of neuro-oncology, working with both patients and family caregivers to improve outcomes and health care delivery.

Summary

Dr. Shiffman's research focuses on tobacco use and nicotine dependence and their development, the nicotine withdrawal syndrome, smoking relapse, behavioral and pharmacological treatment for smoking, and tobacco control. Dr. Shiffman is currently conducting two trials, both focused on non-daily smokers, who are a substantial and growing fraction of adult smokers. The first study focuses on assessing the effects of switching to very low nicotine content cigarettes (VLNCCs) among intermittent smokers (ITS). This is a two-arm randomized study with an own-cigarette baseline control. After a 2-week baseline period smoking their own cigarettes, ITS will be randomized for 10 weeks to smoke experimental cigarettes, either (a) normal nicotine content cigarettes, or VLNCCs. Change in cigarette consumption is the primary end-point, and biomarkers of smoke exposure and measures of smoking intensity are also assessed. The second study focuses on the effect of as-needed oral Nicotine Replacement Therapy (NRT) for smoking cessation in ITS, and to study the process of relapse in ITS, using Ecological Momentary Assessment (EMA). Reviews of ITS have called for research on ITS' relapse process, and for evaluation of cessation methods, including medications, among ITS. This will be a double-blind, randomized, placebo-controlled trial of oral NRT for smoking cessation in ITS. EMA data collection includes two weeks of baseline data on ad lib smoking patterns and 6 weeks of post-quit data, using methods we successfully fielded in our previous research. This will capture data on craving, withdrawal, and relapse among ITS, and relate relapse contexts to baseline smoking patterns.

Summary

My research focuses on the intersection of media and health, with a particular interest in investigating how we can use media and technology in ways that promote health. My work has examined the association between social media use and mental health outcomes, the spread of misinformation on social media, and online marketing of emerging tobacco products (e.g. hookah, e-cigarettes). Much of this work uses novel methodologies such as combining in-depth qualitative, quantitative, and social network data. I am currently conducting pilot trials in area high schools to test a media literacy-based tobacco prevention program as well as a large-scale study investigating nicotine and tobacco misinformation on youth-oriented social media platforms. As a part of my research, I utilize community-based participatory methods, especially when working with adolescents and emerging adults. I am also committed to developing the research, presentation, and publishing skills of undergraduate and graduate students by providing enriching mentoring opportunities.

Summary

Lauren Terhorst is a professor in the Department of Occupational Therapy with secondary appointments in the School of Nursing and the Clinical and Translational Science Institute. She is also the co-director of the SHRS Data Center. Her primary area of expertise is related to applications of statistical methodology in health science research. She is a co-investigator and biostatistician on several grants from agencies such as the National Institutes of Health and Patient Centered Outcomes Research Institute (PCORI). She serves as a reviewer for peer-reviewed journals and national funding agencies. She has more than 100 peer-reviewed publications in journals of high impact in health science. She is active in teaching and mentors SHRS students in methodology and statistics.

Summary

Dr. Thomas is a leader in promoting self-advocacy among patients with cancer. She has developed a model and measure of how patients advocate for their needs and priorities within the context of their cancer experience – the Self-Advocacy in Cancer Survivorship Model. Currently, her research evaluates the impact of a theoretically-based, patient-centered serious game (a motivational video game) intervention on women with advanced cancer’s self-advocacy skills, symptom burden, and use of health care services (R37CA262025 - NCT04813276). She also works with clinical nurses to understand how nurses can promote self-advocacy among their patients. Dr. Thomas’s other areas of interest include cancer symptom management, caregiver burden, instrument development and testing, and financial distress related to chronic health problems.  

Summary

My research interests focus on studying the relationship between environmental hazards and cancer, examining whether socio-cultural, biological, and behavioral determinants may mediate or moderate these relationships. I use a broad toolkit of research methods, including quantitative and qualitative methods, geographic information systems (GIS), and spatial statistics, to characterize risk factors and test hypotheses. 

Summary

Dr. van Londen is a medical oncologist and geriatrician whose research interests focus on a wide variety of topics relevant to cancer survivorship via multiple collaborations. However, her primary research focus relates to the assessment and management of adverse effects of adjuvant endocrine therapy in older cancer survivors.

Summary

My obesity management and disease prevention experiences encompass several clinical (university-based and private psychology practice), research (NIH clinical trials and translational studies) and training (developing/mentoring diverse practitioners and programs in the community) roles. Most of my work involves the design and pragmatic application of evidence-based lifestyle behavior change interventions as a roadmap for more widespread dissemination of disease prevention programs to benefit public health. I serve as Principal Investigator (PI) in the multi-site longitudinal follow-up of the Diabetes Prevention Program Outcomes Study (DPPOS) cohort to examine: 1) the effectiveness of early metformin treatment (initiated during pre-diabetes) on the development of cardiovascular disease and cancer; 2) the longer term impact of the intensive lifestyle treatment, continued (in less intensive form) during DPPOS; and 3) the clinical course of dysglycemia, associated metabolic abnormalities, and the development of long term disease outcomes among all randomized treatment groups.

Summary

The focus of my research is the genetics of postoperative symptoms. Specifically, I am studying the association of several genes and postoperative and post-discharge nausea and vomiting in women following surgery for breast and ovarian cancer. We would like to be able to understand why some women do not respond to antiemetic medications, and to predict who is at greatest risk.

Summary

I am a medical oncologist specializing in genitourinary cancers. My research interests are in symptom management and quality of life for patients with genitourinary cancers, particularly for patients with prostate cancer undergoing androgen deprivation therapy.