News and Announcements

Learn more about the latest news and accomplishments from UPMC Hillman Cancer Center at the links below.
2025

UPMC Hillman Physician-Scientist Recipient of American Society for Clinical Investigation Award

1/28/2025 - Benjamin Nacev, MD, PhD, was acknowledged by the American Society for Clinical Investigation (ASCI) with a 2025 Young Physician-Scientist Award, which recognizes physician-scientists who are early in their first faculty appointment and have made notable achievements in their research. 

Nourishing T Cells to Fight Cancer

1/28/2025 - A team of researchers led by Greg Delgoffe, PhD, have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a murine model of melanoma compared to those grown in traditional growth media.

Updates to Our Genome Stability Program Leadership

1/21/2025 - Roddy O’Sullivan, PhD, is the next co-leader of our Genome Stability Program (GSP). In this role, Dr. O’Sullvan will help to provide oversight for the development, direction, and coordination of the goals and specific aims of the program. Orlando Schärer, PhD, has also been recognized as a Senior Leader within the GSP and will serve as the chairman of the program’s faculty recruitment committee.

New Report Shows UPMC Hillman Cancer Center's Nearly $4 Billion Economic Impact In Pennsylvania

1/16/2025 - A recent report showed that UPMC Hillman generated $3.98 billion in total economic impact in Pennsylvania through its clinical, research and educational missions in Fiscal Year 2023. 

New Interim Director and Interim Deputy Director Announced

1/15/2025 - Kathryn Schmitz, PhD, MPH, professor of medicine in UPSOM’s Division of Hematology/Oncology, is the new interim director, and José P. Zevallos, MD, MPH, chair of otolaryngology at UPMC and the Dr. Eugene N. Myers Professor and chair of the Department of Otolaryngology at UPSOM, is the new interim deputy director of UPMC Hillman Cancer Center.

Trastuzumab Emtansine Improves Long-Term Survival in HER2 Breast Cancer

1/15/2025 - In patients with high-risk HER2-positive breast cancer, postsurgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared to trastuzumab alone, according to the final results of the phase 3 KATHERINE clinical trial led by Charles Geyer, MD, published in the New England Journal of Medicine.

1/2/2025 - Patients with epithelial ovarian cancer, one of the deadliest gynecologic cancers, who lived in disadvantaged neighborhoods had a worse chance of survival compared to those in more advantaged areas, according to a pilot study published in Gynecologic Oncology led by Francesmary Modugno, PhD.

2024

12/20/2024 - Jason Lohmueller, UPMC Hillman Cancer Center, was selected as one of 12 Pitt faculty members to present their research for the 2025 Senior Vice Chancellor’s Research Seminar Series. Dr. Lohmueller will present his lab’s latest technological development called Universal Adaptor CAR T-cell therapy, which will be capable of targeting multiple antigens produced by various tumor cells simultaneously on solid tumors, which make up the bulk of cancers.  

12/17/2024 - Four of the 12 Pitt faculty selected to present their research for the 2025 Senior Vice Chancellor’s Research Seminar Series are members of UPMC Hillman Cancer Center. Jason Lohmueller will present research on Universal Adaptor CAR T Cell Therapy on Jan 17. Sarah Belcher will present research on equitable cancer medication adherence on Feb. 21. Rachel A. Gottschalk will present research on modeling macrophage signaling on March 14. Hatice Ulka Osmanbeyoglu will present research on integrative multiomics to unravel disease mechanisms on Nov. 14. 

Joel Greenberger and Peter Wipf Elected to the National Academy of Inventors

12/12/2024 - UPMC Hillman Cancer Center members Joel S. Greenberger and Peter Wipf have been named 2024 National Academy of Inventors (NAI) fellows. 

Welcome Natacha De Genna as the Assistant Center Director for Community Outreach and Engagement

12/9/2024 - Natacha De Genna, PhD, is the inaugural Assistant Center Director for Community Outreach and Engagement (COE) at UPMC Hillman Cancer Center.

New Take on Immunotherapy Reinvigorates T cells by Blocking Uptake of Energy-Sapping Cancer Byproducts

12/8/2024 - Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new study that describes how shutting off T cell access to inhibitory metabolites could be a promising new approach to cancer immunotherapy published in Nature Immunology.

Five New Papers Highlight Cancer Inequities, Challenges and Opportunities in South Asia

12/2/2024 - series of five papers published in The Lancet Oncology by a UPMC Hillman Cancer Center-led international team, highlights critical public health challenges related to cancer control in the eight countries that form the South Asian Association for Regional Cooperation and the Rohingya refugee population in Bangladesh

12/2/2024 - Steffi Oesterreich, UPMC Hillman Cancer Center Cancer Biology Program co-lead, honored by the American Association for Cancer Research (AACR) at the San Antonio Breast Cancer Symposium.

Eight UPMC Hillman Cancer Center Members Named Highly Cited Researchers in 2024

11/23/2024 - This week, Clarivate™ named their list of Highly Cited Researchers for 2024 — an elite group that demonstrates significant and broad influence in their field of research. UPMC Hillman Cancer Center has eight members named to the list, including Greg Delgoffe, Kirk Erickson, Valerian Kagan, John Kirkwood, Jeremy Rich, Yulia Tyurina, Dario Vignaliand Simon Watkins. 

11/22/2024 - A team with UPMC Hillman Cancer Center and Pitt faculty and students won first place for their poster presentation at the 2024 Medical Organization of Latino Advancement-National Association of Medical Spanish (MOLA-NAMS) Conference. 

11/12/2024 - Addition of the immunotherapy drug pembrolizumab to standard of care for patients with advanced soft tissue sarcoma of the limb significantly improved disease-free survival, according to the results of the SU2C-SARC032 clinical trial led published in The Lancet by a team of reseachers including UPMC Hillman Cancer Center's Yvonne Mowery.

Novel Immunotherapy Combo Shows Promise in Melanoma

11/7/2024 - Pre-surgery treatment with the novel drug vidutolimod and the PD-1 checkpoint inhibitor nivolumab led to tumor control in 55% of patients with stage 3 cutaneous melanoma, according to the results of a single-arm phase 2 clinical trial led by the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute (NCI).

10/8/2024 - UPMC Hillman Cancer Center member, Alexander Sorkin, has been recognized by ScholarGPS as No. 2 in the world for his lifetime of work in endocytosis as part of their Highly Ranked Scholars classification. 

10/4/2024 - Of the 12 researchers from the University of Pittsburgh included in Research.com’s 2024 ranking of the “best female scientists in the world,” five are faculty at UPMC Hillman Cancer Center: Jane A. Cauley, Anne B. Newman, Theresa L. Nimick-Whiteside, Angela M. Gronenborn, and Donna B. Stolz.

UPMC Hillman Cancer Center Exercise Oncologist Receives Prestigious Presidential Award

9/13/2024 - Kathryn Schmitz, PhD, MPH, has been selected by The President's Council on Sports, Fitness & Nutrition to receive a 2024 Lifetime Impact Award.

Michalopoulos Receives 2024 AASLD Distinguished Achievement Award

8/27/2024 - George K. Michalopoulos, UPMC Hillman Cancer Center member, selected to receive the 2024 American Association for the Study of Liver Diseases (AASLD) Distinguished Achievement Award.

New Study Supports Annual Breast Cancer Screening for Women Over 40

8/27/2024 - Women diagnosed with breast cancer who had regular screening mammograms every year were less likely to have late-stage cancer and had higher overall survival than those who received screening every other year or less often, according to new research led by UPMC Hillman researchers published in the Journal of Clinical Oncology.

Nivolumab and Relatlimab Work Together to Treat Advanced Melanoma

8/13/2024 - UPMC Hillman Cancer Center researchers showed the combination boosted the immune system’s ability to recognize and attack cancer cells, even though some immune cells showed signs of being tired from fighting against the cancer cells.

Jeremy Rich, MD, MHS, MBA, Announced Interim Director

8/7/2024 - Dr. Rich will serve as interim director of UPMC Hillman Cancer Center following the announced departure of Robert Ferris, MD, PhD, and during the national search for a new director.

When Tumors Collide: Analysis of Mixed-Type Breast Cancer Reveals Complexity

7/24/2024 - Histopathological/molecular profiling of individual tumor regions for patients with mixed invasive ductal and lobular carcinoma may guide clinical decision-making and benefit patients, according to study published in PNAS led by UPMC Hillman Cancer Center researchers.

Michelle Williams, PhD, Joins UPMC Hillman Cancer Center

7/23/2024 - Dr. Williams is Assistant Professor in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh. 

Joel Maust, PhD, and Alina Chaudry, MPH, Join UPMC Hillman Cancer Center

7/19/2024 - Two new members have joined the Research Administration team at UPMC Hillman Cancer Center. Dr. Joel Maust joined May 1, 2024 as a scientific writer and Alina Chaudry joined July 1, 2024 as a research program manager. 

Hadjipanayis Elected AANS/CNS Tumor Section Chair

7/18/2024 - Costas G. Hadjipanayis, UPMC Hillman Cancer Center member, elected chair of the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors.

Devanjan Sikder, DVM, PhD, Joins UPMC Hillman Cancer Center

7/18/2024 - Dr. "Dev" Sikder is Associate Professor in the Department of Medicine, Division of Malignant Hematology/Oncology at the University of Pittsburgh and Director of the Hematopoietic Stem Cell (HSC) Lab and Immune Monitoring and Cellular Products Laboratory (IMCPL).

7/17/2024 - UPMC Hillman Cancer Center researchers have developed a nudge, embedded in electronic health records, that could reduce overtreatment of older patients with early-stage breast cancer. 

Hormone Therapy for Breast Cancer Linked with Lower Dementia Risk

7/16/2024 - Hormone modulating therapy used for the treatment of breast cancer was associated with a 7% lower risk of developing Alzheimer’s disease and related dementias later in life, according to a new study published in JAMA Network Open by a team of researches, including UPMC Hillman Cancer Center researcher Francesmary Modugno.

New CTP and CIIP Research Program Leads

5/30/2024 - After a search, thorough consideration of several highly talented individuals, and consultation with our external advisory board UPMC Hillman Cancer Center is pleased to announce Dr. Jan Beumer as our new co-leader for the Cancer Therapeutics Program (CTP) and Dr. Greg Delgoffe as our new co-leader for Cancer Immunology & Immunotherapy Program (CIIP).

Study Suggests It May Be Safe to De-escalate Surgery in Middle-Aged Breast Cancer Patients

5/22/2024 - Surgery involving sentinel lymph node biopsy for middle-aged women with estrogen receptor-positive (ER+) breast cancer may do more harm than good, according to a new study led by UPMC Hillman Cancer Center researchers.  

Electronic Survey Helps Integrate Exercise as Standard of Care at UPMC Hillman Cancer Center

5/9/2024 - For people living with cancer, exercise can improve quality of life, sleep and energy levels and help with side effects of cancer treatment. And even though physicians and oncology researchers agree about these benefits, a recent survey found that only 15% of cancer patients had been referred to an exercise program.  

Dogma-Challenging Telomere Findings May Offer New Insights for Cancer Treatments

5/7/2024 - A new study led by UUPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.  

Affordable Care Act Expansions Improved Access to Cancer Care, Study Suggests

5/6/2024 - Insurance expansions under the Affordable Care Act (ACA) were linked with an increase in patients receiving care at accredited cancer hospitals in Pennsylvania, according to a study published in Health Services Research by University of Pittsburgh researchers.  

Jeffrey Brodsky, PhD, Yuan Chang, MD, and Patrick Moore, MD, MPH, Elected to American Academy of Arts and Sciences

4/24/2024 - Drs. Brodsky, Chang, and Moore, faculty members of UPMC Hillman Cancer Center, have been elected to the the American Academy of Arts and Sciences. The Academy is a beacon of excellence and leadership across a wide range of disciplines with the mission to unite leaders and innovators from every field of human endeavor to advance the public good.  

Bennett Van Houten, PhD, Named AAAS Fellow

4/18/2024 - Dr. Van Houten, co-director of the Genome Stability Program at UPMC Hillman Cancer Center, and Richard M. Cyert Professor of Molecular Oncology and professor of pharmacology and chemical biology in the University of Pittsburgh School of Medicine, has been recognized by AAAS with one of the most distinct honors in the scientific community. 

New Insights Could Unlock Immunotherapy for Rare, Deadly Eye Cancer

4/16/2024 - New research from UPMC Hillman Cancer Center explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient’s T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer. 

Norman Wolmark, MD, Receives the Medallion for the Advancement of Surgical Care

4/10/2024 - The Medallion for the Advancement of Surgical Care was awarded to Dr. Wolmark by the American Surgical Association, our nation’s oldest and most prestigious surgical association. 

Marija Balic, MD, ScD, MBA, Joins UPMC Hillman Cancer Center

3/27/2024 - Dr. Balic is professor in the Department of Medicine, Division of Hematology/Oncology at the University of Pittsburgh, sees patients at the outpatient clinic of UPMC Magee Breast Cancer Clinic, and serves as co-director of Magee Women's Cancer Program, clinical co-leader of the Women’s Cancer Research Center, and Scientific Director of the NSABP Foundation Translational Research Program. 

CAMILLA Trial Results Offer Potential New Colorectal Cancer Treatment Option

3/11/2024 - Researchers led by Anwaar Saeed, MD, published their results from the CAMILLA trial showing that combining cabozantinib and durvalumab in patients with chemotherapy-refractory colorectal cancer is a promising treatment, potentially expanding treatment options for patients with microsatellite stable advanced colorectal cancer.

Saad Sheikh, MD, Joins UPMC Hillman Cancer Center

3/5/2024 - Dr. Sheikh will develop an active research program focusing on basic and translational research in pediatric cancers and will work to develop collaborations among other members of the Pediatric Cancers Disease Team and UPMC Hillman.

Tatiana Moiseeva, PhD, Joins UPMC Hillman Cancer Center

3/1/2024 - Dr. Moiseeva will develop an independently-funded research program in genome stability, which includes collaborative efforts with basic and clinical faculty across the cancer center. She is primarily interested in the investigation of the initiation in DNA replication in human cells.

New Test Could Predict Immunotherapy Responders for Broader Range of Cancers than Current Tools

2/13/2024 - A newly identified genetic marker could potentially predict which patients are likely to respond to immunotherapy in cancer types that have lacked such tools until now, according to a study published in Cancer Immunology Research, led by University of Pittsburgh researchers.

Novel Clinical Trial to Treat Glioblastoma with Innovative Photodynamic Therapy

2/6/2024 - A first of its kind clinical trial in the United States to treat glioblastoma will be launching in early 2024 at UPMC and UPMC Hillman Cancer Center led by Jan Drappatz, MD, and Costas G. Hadjipanayis, MD, PhD.

Growth Factor Administration in Pancreatic Cancer Treatment

1/31/2024 - Led by Amer Zureikat, MD, UPMC Hillman Cancer Center researchers and colleagues found that the administration of G-CSF during neoadjuvant therapy was associated with worse oncologic outcomes and overall survival in patients with resected pancreatic cancer.

Continuing a Legacy of Excellence

1/30/2024 - As Chuck Bogosta's 25-year tenure with UPMC concludes, current UPMC Hillman Cancer Center president Elizabeth Wild steps into an expanded executive leadership role, assuming full administrative leadership of the Hillman network.

1/24/2024 - With colleagues from multiple institutions, Dr. Bailey discusses the overall improvements of pediatric cancer outcomes, while recognizing the ongoing challenges in the disparity of outcomes across cancer types and patients.

Kathryn Schmitz, PhD, MPH, Named Associate Director of Population Sciences

1/2/2023 - Kathryn Schmitz, PhD, MPH, has been named the new Associate Director of Population Sciences. Dr. Schmitz is an exercise oncology researcher and professor of medicine in the Division of Hematology/Oncology as well as the director of UPMC Hillman’s Exercise Oncology efforts.

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